DK124950B - Analogifremgangsmåde til fremstilling af 1-phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dioner. - Google Patents

Analogifremgangsmåde til fremstilling af 1-phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dioner.

Info

Publication number
DK124950B
DK124950B DK566968AA DK566968A DK124950B DK 124950 B DK124950 B DK 124950B DK 566968A A DK566968A A DK 566968AA DK 566968 A DK566968 A DK 566968A DK 124950 B DK124950 B DK 124950B
Authority
DK
Denmark
Prior art keywords
diones
benzodiazepine
phenyl
alkyl
preparation
Prior art date
Application number
DK566968AA
Other languages
Danish (da)
English (en)
Inventor
K Zeile
R Giesemann
K Weber
P Danneberg
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of DK124950B publication Critical patent/DK124950B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK566968AA 1967-11-24 1968-11-20 Analogifremgangsmåde til fremstilling af 1-phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dioner. DK124950B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Publications (1)

Publication Number Publication Date
DK124950B true DK124950B (da) 1972-12-11

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
DK566968AA DK124950B (da) 1967-11-24 1968-11-20 Analogifremgangsmåde til fremstilling af 1-phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dioner.

Country Status (13)

Country Link
AT (1) AT280290B (enExample)
BE (1) BE724364A (enExample)
BR (1) BR6804236D0 (enExample)
CH (1) CH523265A (enExample)
DE (1) DE1810423B2 (enExample)
DK (1) DK124950B (enExample)
ES (2) ES360410A1 (enExample)
FR (2) FR1593335A (enExample)
GB (1) GB1173540A (enExample)
IE (1) IE32504B1 (enExample)
IL (1) IL31146A (enExample)
NL (1) NL6815755A (enExample)
SE (1) SE356979B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (de) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim Neue substituiert 1,3-Dihydro-2H-1 ^-benzodiazepine^-one
BE793460A (fr) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim Nouvelles 1-aryl-3h,1,4-benzodiazepine-2,5-(1h
WO2000066106A2 (en) 1999-04-30 2000-11-09 The Regents Of The University Of Michigan Use of benzodiazepines for treating autoimmune diseases induced by apoptosis
US7144880B2 (en) 1999-04-30 2006-12-05 Regents Of The University Of Michigan Compositions relating to novel compounds and targets thereof
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
WO2006074358A1 (en) 2005-01-03 2006-07-13 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
WO2007053193A2 (en) 2005-06-01 2007-05-10 The Regents Of The University Of Michigan Unsolvated benzodiazepine compositions and methods
AU2006308655B2 (en) 2005-11-01 2010-09-23 The Regents Of The University Of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
CA2659549C (en) 2006-06-09 2013-07-30 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
CA2783589A1 (en) 2007-03-09 2008-09-18 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
EP2146722A4 (en) * 2007-05-10 2011-08-03 Amr Technology Inc ARYL AND HETEROARYL SUBSTITUTED TETRAHYDROBENZO-1,4-DIAZEPINES AND THEIR USE FOR BLOCKING THE RECOVERY OF NOREPINEPHRIN, DOPAMINE AND SEROTONINE
ES2614498T3 (es) 2007-09-14 2017-05-31 The Regents Of The University Of Michigan Inhibidores de ATPasa F1F0 y métodos relacionados
UA99839C2 (ru) 2007-11-06 2012-10-10 Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган Бензодиазепиноновые соединения, применяемые при лечении кожных состояний
JP5567573B2 (ja) 2008-09-11 2014-08-06 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン アリールグアニジンf1f0−atpアーゼ阻害剤およびそれと関連する方法
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
EP2470020A4 (en) 2009-09-18 2013-03-13 Univ Michigan BENZODIAZEPINONE COMPOUNDS AND TREATMENT METHODS THEREWITH
US9126978B2 (en) 2009-11-17 2015-09-08 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
JP5856064B2 (ja) 2009-11-17 2016-02-09 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 治療特性を有する1,4−ベンゾジアゼピン−2,5−ジオンおよび関連化合物
US11465978B2 (en) 2013-09-11 2022-10-11 The Administrators Of The Tulane Educational Fund Anthranilic amides and the use thereof

Also Published As

Publication number Publication date
SE356979B (enExample) 1973-06-12
BE724364A (enExample) 1969-05-22
FR1593335A (enExample) 1970-05-25
DE1810423A1 (de) 1969-10-09
BR6804236D0 (pt) 1973-02-08
FR8310M (enExample) 1970-11-23
IL31146A (en) 1972-04-27
AT280290B (de) 1970-04-10
CH523265A (de) 1972-05-31
NL6815755A (enExample) 1969-05-28
GB1173540A (en) 1969-12-10
IE32504B1 (en) 1973-08-22
ES378977A1 (es) 1973-01-16
IE32504L (en) 1969-05-24
ES360410A1 (es) 1970-11-01
DE1810423C3 (enExample) 1973-10-11
IL31146A0 (en) 1969-01-29
DE1810423B2 (de) 1973-03-22

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