ID902B - Turunan-turunan imidazoindolizina dan proses pembuatannya - Google Patents

Turunan-turunan imidazoindolizina dan proses pembuatannya

Info

Publication number
ID902B
ID902B IDP469892A ID924698A ID902B ID 902 B ID902 B ID 902B ID P469892 A IDP469892 A ID P469892A ID 924698 A ID924698 A ID 924698A ID 902 B ID902 B ID 902B
Authority
ID
Indonesia
Prior art keywords
substituted
pharmaceutically acceptable
imidazoindolizine
unsubstituted phenyl
imidazoindolizina
Prior art date
Application number
IDP469892A
Other languages
English (en)
Indonesian (id)
Inventor
Yasushi Honma
Yasuo Sekine
Sumihiro Nomura
Kazuaki Naito
Hiroshi Narita
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of ID902B publication Critical patent/ID902B/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
IDP469892A 1991-09-10 1992-09-10 Turunan-turunan imidazoindolizina dan proses pembuatannya ID902B (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30856091 1991-09-10
JP5304492 1992-01-27

Publications (1)

Publication Number Publication Date
ID902B true ID902B (id) 1996-09-09

Family

ID=26393753

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP469892A ID902B (id) 1991-09-10 1992-09-10 Turunan-turunan imidazoindolizina dan proses pembuatannya

Country Status (16)

Country Link
US (1) US5268377A (hr)
EP (1) EP0531876B1 (hr)
JP (1) JP2590797B2 (hr)
KR (1) KR0168457B1 (hr)
AT (1) ATE146474T1 (hr)
AU (1) AU644539B2 (hr)
CA (1) CA2077420C (hr)
DE (1) DE69216013T2 (hr)
DK (1) DK0531876T3 (hr)
ES (1) ES2098403T3 (hr)
FI (1) FI98369C (hr)
GR (1) GR3022106T3 (hr)
ID (1) ID902B (hr)
IL (1) IL103021A (hr)
MY (1) MY129927A (hr)
SG (1) SG42962A1 (hr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06271576A (ja) * 1993-03-19 1994-09-27 Upjohn Co:The イミダゾール誘導体の製法
FR2712592B1 (fr) * 1993-11-17 1995-12-22 Adir Nouveaux dérivés tricycliques azotés, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
BR112015030326A2 (pt) 2013-06-05 2017-08-29 Synergy Pharmaceuticals Inc Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
TW201811759A (zh) 2016-06-29 2018-04-01 加拿大蒙特利爾大學 二芳基甲基雜環

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1047148A1 (ru) * 1981-03-30 1986-12-23 Институт физико-органической химии и углехимии АН УССР Бензилиденпроизводные имидазо-[4,5-L]-индолизинов,обладающие бактериостатической и фунгистатической активностью
US4686226A (en) * 1985-09-03 1987-08-11 Merck & Co., Inc. Substituted benzo[b]furo- and benzo[b]thieno quinolizines
US4812462A (en) * 1986-04-01 1989-03-14 Warner-Lambert Company 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid analogs having antihypertensive activity
US4816463A (en) * 1986-04-01 1989-03-28 Warner-Lambert Company Substituted diimidazo [1,5-a: 4',5'-d]pyridines having antihypertensive activity
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
DE3928177A1 (de) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
IL96019A0 (en) * 1989-10-31 1991-07-18 Fujisawa Pharmaceutical Co Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
JPH05279365A (ja) 1993-10-26
JP2590797B2 (ja) 1997-03-12
CA2077420C (en) 1998-08-25
IL103021A0 (en) 1993-02-21
ES2098403T3 (es) 1997-05-01
EP0531876A2 (en) 1993-03-17
AU2205692A (en) 1993-03-11
EP0531876B1 (en) 1996-12-18
SG42962A1 (en) 1997-10-17
CA2077420A1 (en) 1993-03-11
FI98369B (fi) 1997-02-28
GR3022106T3 (en) 1997-03-31
DK0531876T3 (hr) 1997-02-17
FI98369C (fi) 1997-06-10
US5268377A (en) 1993-12-07
DE69216013D1 (de) 1997-01-30
FI924043A0 (fi) 1992-09-10
KR930006024A (ko) 1993-04-20
EP0531876A3 (en) 1993-05-05
ATE146474T1 (de) 1997-01-15
KR0168457B1 (ko) 1999-01-15
AU644539B2 (en) 1993-12-09
DE69216013T2 (de) 1997-05-07
FI924043A (fi) 1993-03-11
MY129927A (en) 2007-05-31
IL103021A (en) 1996-10-16

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