ID29236A - Benzopiran-benzopiran dan benzoksepin-benzoksepin, komposisi-komposisi famaseutikal yang mengandungnya, dan proses penyiapannya - Google Patents

Benzopiran-benzopiran dan benzoksepin-benzoksepin, komposisi-komposisi famaseutikal yang mengandungnya, dan proses penyiapannya

Info

Publication number
ID29236A
ID29236A IDW00200101656A ID20011656A ID29236A ID 29236 A ID29236 A ID 29236A ID W00200101656 A IDW00200101656 A ID W00200101656A ID 20011656 A ID20011656 A ID 20011656A ID 29236 A ID29236 A ID 29236A
Authority
ID
Indonesia
Prior art keywords
famaseutical
benzoxins
benzopirans
compositions
beneficial
Prior art date
Application number
IDW00200101656A
Other languages
English (en)
Indonesian (id)
Inventor
Michel Brunet
Jean J Zeiller
Jean J Berthelon
Francis Cintard
Gauy Augert
Daniel Guerrier
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ID29236A publication Critical patent/ID29236A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06—Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
IDW00200101656A 1998-12-29 1999-12-20 Benzopiran-benzopiran dan benzoksepin-benzoksepin, komposisi-komposisi famaseutikal yang mengandungnya, dan proses penyiapannya ID29236A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9816574A FR2787789B1 (fr) 1998-12-29 1998-12-29 Benzopyranes et benzoxepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparations

Publications (1)

Publication Number Publication Date
ID29236A true ID29236A (id) 2001-08-16

Family

ID=9534619

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW00200101656A ID29236A (id) 1998-12-29 1999-12-20 Benzopiran-benzopiran dan benzoksepin-benzoksepin, komposisi-komposisi famaseutikal yang mengandungnya, dan proses penyiapannya

Country Status (19)

Country Link
US (1) US6596758B1 (ko)
EP (1) EP1140893B1 (ko)
JP (1) JP4607331B2 (ko)
KR (1) KR100684088B1 (ko)
CN (2) CN1173967C (ko)
AU (1) AU759892B2 (ko)
BR (1) BR9916633A (ko)
CA (1) CA2356680C (ko)
CZ (1) CZ300086B6 (ko)
FR (1) FR2787789B1 (ko)
HK (1) HK1047584B (ko)
HU (1) HUP0104839A3 (ko)
ID (1) ID29236A (ko)
NO (1) NO20013242L (ko)
PL (1) PL196524B1 (ko)
RU (1) RU2228333C2 (ko)
SK (1) SK9022001A3 (ko)
WO (1) WO2000039113A1 (ko)
ZA (1) ZA200106177B (ko)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1432696A1 (en) * 2001-10-04 2004-06-30 Wyeth Chroman derivatives as 5-hydroxytryptamine-6 ligands
FR2845386B1 (fr) * 2002-10-07 2006-06-30 Merck Sante Sas Nouveaux derives metastables de benzoxepines utilisables dans le traitement des dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparation
US7456205B2 (en) 2003-02-26 2008-11-25 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Benzopyran compounds, process for preparing the same and their use
NZ546834A (en) * 2003-10-01 2010-03-26 Adolor Corp Spirocyclic heterocyclic derivatives and methods of their use
US6887896B1 (en) * 2003-10-29 2005-05-03 Allergan, Inc. 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity
SI1535612T1 (sl) * 2003-11-28 2006-12-31 Merck Sante Sas Zdravljenje hiperurikemije
DE602004006085T2 (de) * 2004-04-27 2007-12-27 Merck Santé Neue 1-Methoxy-2-phenyl-ethene zur Herstellung von 5-Carboxaldehyde-2-3-dihydrobenzoxepinen
PT1600446E (pt) * 2004-05-18 2008-01-23 Merck Sante Sas Novos derivados de 3,3-dimetil-5-ciano-benzoxepina úteis para a preparação de derivados de 5-formil-benzoxepina
DK1609786T3 (da) * 2004-06-25 2011-11-14 Merck Sante Sas Nye 5-alkenon-3,3-dimethyl-benzoxepin-derivater til anvendelse i fremstillingen af antidiabetiske pentadiensyrer
US20070021612A1 (en) * 2004-11-04 2007-01-25 University Of Notre Dame Du Lac Processes and compounds for preparing histone deacetylase inhibitors and intermediates thereof
US7235688B1 (en) 2004-11-04 2007-06-26 University Of Notre Dame Du Lac Process for preparing histone deacetylase inhibitors and intermediates thereof
CA2589363A1 (en) * 2004-12-13 2006-06-22 Eli Lilly And Company Spiro derivatives as lipoxygenase inhibitors
EP2532390B1 (en) * 2005-02-16 2016-08-17 Md Bioalpha Co., Ltd. Pharmaceutical composition for liver diseases.
US7598261B2 (en) * 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) * 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
AU2007294968A1 (en) * 2006-09-12 2008-03-20 Adolor Corporation Use of N-containing spirocompounds for the enhancement of cognitive function
CN101172978A (zh) * 2006-11-02 2008-05-07 中国人民解放军军事医学科学院毒物药物研究所 六元杂环化合物,其制备方法及其医药用途
US20100173983A1 (en) * 2007-03-16 2010-07-08 David Brown Method for inducing autophagy
ES2562798T3 (es) * 2008-08-09 2016-03-08 Merck Patent Gmbh Uso de compuestos de indol como cosmético
US20110144130A1 (en) * 2008-08-12 2011-06-16 Merck Patent Gesellschaft Mit Beschrankter Haftung Use of 5-(7-methoxy-3,3-dimethyl-2,3-dihydro-1-benzoxepin-5-yl)-3-methyl-penta-2,4-dienoic acid as a cosmetic
US10221143B2 (en) 2015-03-03 2019-03-05 Arizona Board Of Regents On Behalf Of Arizona State University Substituted anilines for treatment of animal diseases
US10112917B2 (en) 2015-03-03 2018-10-30 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic compounds
US10231947B2 (en) 2017-01-23 2019-03-19 Arizona Board Of Regents On Behalf Of Arizona State University Isochroman compounds and methods of use thereof
US10238655B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Dihydroindene and tetrahydronaphthalene compounds
US10238626B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic compounds
CN108371712B (zh) * 2018-01-18 2020-12-25 华北理工大学 咖啡因与PPARγ激动剂联合制备AD药物中的用途
WO2022053416A1 (en) 2020-09-08 2022-03-17 Merck Patent Gmbh Improvement of water-holding capacity of skin by oxeglitazar

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004744A (en) * 1988-12-13 1991-04-02 Bayer Aktiengesellschaft Pyridazinones as pesticides
EP0412939A3 (en) * 1989-08-11 1991-09-04 Ciba-Geigy Ag Certain benzopyran and benzothiopyran derivatives
US4946860A (en) * 1989-11-03 1990-08-07 Rorer Pharmaceutical Corporation Benzothiopyranyl derivatives as HMG-CoA reductase inhibitors
ATE163544T1 (de) * 1991-12-18 1998-03-15 Salk Inst For Biological Studi Mitteln zur modulierung von verfahren durch retinoid rezeptoren und dafür nützliche verbindungen
US5391569A (en) * 1992-09-29 1995-02-21 Adir Et Compagnie New chromene compounds having a triene side chain
DE69516903T2 (de) * 1994-12-30 2000-10-26 Ligand Pharmaceuticals, Inc. Retinoid trienverbindungen und verfahren
US5675033A (en) * 1995-06-06 1997-10-07 Allergan 2,4-pentadienoic acid derivatives having retinoid-like biological activity

Also Published As

Publication number Publication date
CN1554651A (zh) 2004-12-15
FR2787789B1 (fr) 2002-06-14
JP2003517449A (ja) 2003-05-27
AU2432900A (en) 2000-07-31
JP4607331B2 (ja) 2011-01-05
BR9916633A (pt) 2001-09-25
EP1140893B1 (en) 2003-03-05
PL196524B1 (pl) 2008-01-31
NO20013242D0 (no) 2001-06-28
CA2356680C (en) 2010-03-23
RU2228333C2 (ru) 2004-05-10
HUP0104839A2 (hu) 2002-04-29
CN1173967C (zh) 2004-11-03
PL349448A1 (en) 2002-07-29
CN1359383A (zh) 2002-07-17
HK1047584B (zh) 2005-05-27
WO2000039113A1 (en) 2000-07-06
HUP0104839A3 (en) 2003-01-28
NO20013242L (no) 2001-06-28
KR20010101339A (ko) 2001-11-14
CN1307171C (zh) 2007-03-28
KR100684088B1 (ko) 2007-02-16
CZ20012387A3 (cs) 2001-11-14
EP1140893A1 (en) 2001-10-10
ZA200106177B (en) 2002-12-24
AU759892B2 (en) 2003-05-01
CZ300086B6 (cs) 2009-01-28
HK1047584A1 (en) 2003-02-28
CA2356680A1 (en) 2000-07-06
US6596758B1 (en) 2003-07-22
SK9022001A3 (en) 2002-04-04
FR2787789A1 (fr) 2000-06-30

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