ID27206A - Generasi produk-produk perbanyakan gena dari protein-protein fusi simerik melalui pemutusan endoprotease ubikuitus - Google Patents
Generasi produk-produk perbanyakan gena dari protein-protein fusi simerik melalui pemutusan endoprotease ubikuitusInfo
- Publication number
- ID27206A ID27206A IDW20002666A ID20002666A ID27206A ID 27206 A ID27206 A ID 27206A ID W20002666 A IDW20002666 A ID W20002666A ID 20002666 A ID20002666 A ID 20002666A ID 27206 A ID27206 A ID 27206A
- Authority
- ID
- Indonesia
- Prior art keywords
- expression
- sequence encoding
- endoprotease
- ubikuitus
- simeric
- Prior art date
Links
- 101710118538 Protease Proteins 0.000 title abstract 2
- 108020001507 fusion proteins Proteins 0.000 title abstract 2
- 102000037865 fusion proteins Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000002067 Protein Subunits Human genes 0.000 abstract 2
- 108010001267 Protein Subunits Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5406—IL-4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5425—IL-9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Sorting Of Articles (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9810999.4A GB9810999D0 (en) | 1998-05-21 | 1998-05-21 | Materials and methods relating to the expression of genes |
Publications (1)
Publication Number | Publication Date |
---|---|
ID27206A true ID27206A (id) | 2001-03-08 |
Family
ID=10832516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW20002666A ID27206A (id) | 1998-05-21 | 1999-05-21 | Generasi produk-produk perbanyakan gena dari protein-protein fusi simerik melalui pemutusan endoprotease ubikuitus |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1080206B1 (id) |
JP (1) | JP2002515251A (id) |
KR (1) | KR20010052383A (id) |
CN (1) | CN1308679A (id) |
AT (1) | ATE236259T1 (id) |
AU (1) | AU753785B2 (id) |
CA (1) | CA2333144A1 (id) |
DE (1) | DE69906509D1 (id) |
ES (1) | ES2201718T3 (id) |
GB (1) | GB9810999D0 (id) |
ID (1) | ID27206A (id) |
NZ (1) | NZ508863A (id) |
WO (1) | WO1999060135A1 (id) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6586411B1 (en) * | 2000-08-16 | 2003-07-01 | Mayo Foundation For Medical Education And Research | System for monitoring the location of transgenes |
AU7593001A (en) | 2000-07-14 | 2002-01-30 | Zycos Inc | Alpha-msh related compounds and methods of use |
EP1369128A1 (en) * | 2002-06-07 | 2003-12-10 | Procorde GmbH | Inhibitors of glycoprotein VI and their therapeutic use |
WO2004103295A2 (en) * | 2003-05-14 | 2004-12-02 | Bayer Pharmaceuticals Corporation | Interleukin-9 antagonist muteins and their pharmacological methods of use |
US7709224B2 (en) * | 2003-06-03 | 2010-05-04 | Biosante Pharmaceuticals, Inc. | Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site |
US7485291B2 (en) * | 2003-06-03 | 2009-02-03 | Cell Genesys, Inc. | Compositions and methods for generating multiple polypeptides from a single vector using a virus derived peptide cleavage site, and uses thereof |
FR2856069A1 (fr) * | 2003-06-10 | 2004-12-17 | Bionexis | Molecules de ciblage et de liberation de composes therapeutiques et leur utilisation |
CA2615983A1 (en) | 2005-07-21 | 2007-02-01 | Abbott Laboratories | Multiple gene expression including sorf constructs and methods with polyproteins, pro-proteins, and proteolysis |
WO2009032954A1 (en) * | 2007-09-04 | 2009-03-12 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Deletions in domain ii of pseudomonas exotoxin a that reduce non-specific toxicity |
US8715964B2 (en) | 2008-05-11 | 2014-05-06 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Expression of IL-12 family heterodimers |
WO2011042874A1 (en) * | 2009-10-06 | 2011-04-14 | Ecole Polytechnique Federale De Lausanne (Epfl) | Visualization of proprotein convertase activity in living cells and tissues |
US9428736B2 (en) | 2010-09-02 | 2016-08-30 | Mayo Foundation For Medical Education And Research | Vesicular stomatitis viruses |
US9951117B2 (en) | 2010-09-02 | 2018-04-24 | Mayo Foundation For Medical Education And Research | Vesicular stomatitis viruses |
US20170291934A1 (en) * | 2014-09-22 | 2017-10-12 | Charles C. Reed | Improved therapeutic control of heterodimeric and single chain forms of interleukin-12 |
AU2016334401A1 (en) * | 2015-10-10 | 2018-04-26 | Intrexon Corporation | Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12 |
EP3715367B1 (en) * | 2018-09-17 | 2024-06-12 | GI Innovation, Inc. | Fusion protein comprising il-2 protein and cd80 protein, and use thereof |
WO2020198145A1 (en) * | 2019-03-22 | 2020-10-01 | The Johns Hopkins University | Gene delivery particles to induce tumor-derived antigen presenting cells |
AU2022246917A1 (en) * | 2021-04-02 | 2023-10-12 | Krystal Biotech, Inc. | Viral vectors for cancer therapy |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0212532A1 (en) * | 1985-08-12 | 1987-03-04 | Syntex (U.S.A.) Inc. | Method for producing fusion proteins |
DE69004964T2 (de) * | 1989-08-11 | 1994-03-24 | Zymogenetics Inc | Zellenzuchtverfahren für die produktion von aktiviertem protein-c. |
AU716466B2 (en) * | 1995-09-27 | 2000-02-24 | Medical Research Council | Recombinant viruses incorporating a protease cleavable protein |
-
1998
- 1998-05-21 GB GBGB9810999.4A patent/GB9810999D0/en not_active Ceased
-
1999
- 1999-05-21 EP EP99923745A patent/EP1080206B1/en not_active Expired - Lifetime
- 1999-05-21 AU AU40508/99A patent/AU753785B2/en not_active Ceased
- 1999-05-21 AT AT99923745T patent/ATE236259T1/de not_active IP Right Cessation
- 1999-05-21 ID IDW20002666A patent/ID27206A/id unknown
- 1999-05-21 ES ES99923745T patent/ES2201718T3/es not_active Expired - Lifetime
- 1999-05-21 NZ NZ508863A patent/NZ508863A/xx unknown
- 1999-05-21 JP JP2000549741A patent/JP2002515251A/ja active Pending
- 1999-05-21 WO PCT/GB1999/001609 patent/WO1999060135A1/en not_active Application Discontinuation
- 1999-05-21 CN CN99808292A patent/CN1308679A/zh active Pending
- 1999-05-21 KR KR1020007013081A patent/KR20010052383A/ko not_active Application Discontinuation
- 1999-05-21 CA CA002333144A patent/CA2333144A1/en not_active Abandoned
- 1999-05-21 DE DE69906509T patent/DE69906509D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU753785B2 (en) | 2002-10-31 |
WO1999060135A8 (en) | 2000-01-13 |
ES2201718T3 (es) | 2004-03-16 |
ATE236259T1 (de) | 2003-04-15 |
EP1080206B1 (en) | 2003-04-02 |
EP1080206A1 (en) | 2001-03-07 |
NZ508863A (en) | 2003-03-28 |
JP2002515251A (ja) | 2002-05-28 |
KR20010052383A (ko) | 2001-06-25 |
GB9810999D0 (en) | 1998-07-22 |
CN1308679A (zh) | 2001-08-15 |
DE69906509D1 (de) | 2003-05-08 |
CA2333144A1 (en) | 1999-11-25 |
WO1999060135A1 (en) | 1999-11-25 |
AU4050899A (en) | 1999-12-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ID27206A (id) | Generasi produk-produk perbanyakan gena dari protein-protein fusi simerik melalui pemutusan endoprotease ubikuitus | |
DK1218504T3 (da) | GL50 molekyler og anvendelser deraf | |
ES2177475T1 (es) | Genes de corynebacterium glutamicum que codifican proteinas de una ruta metabolica. | |
WO2002006457A3 (en) | Novel lipase genes | |
WO2005003315A3 (en) | Compositions and methods for peptide-assisted transfection | |
AU6518386A (en) | Novel vector comprising DNA sequences containing a part of polyhedral structural gene from Bombyx Mori nuclear polyhedrosis virus, and use of said vector to produce gene products by genetic engineering | |
DE60144021D1 (de) | Für zellzyklusproteine kodierende nukleinsäure und deren verwendung | |
WO2000052164A3 (en) | Potassium channel molecules and uses therefor | |
CY1106593T1 (el) | Μια κωδικευουσα ακολουθια mycobacterium tuberculosis για εκφραση ετερολογων πρωτεϊνων | |
WO2002002771A3 (en) | Human sparc-homologous (hsparc-h1) gene and methods and uses thereof | |
WO2001032872A3 (en) | Twik potassium channel molecules and uses therefor | |
WO2003020912A3 (en) | Novel clark protein and nucleic acid molecules and uses therefor | |
SE0303093D0 (sv) | Expression vector, host cell and method for producing fusion proteins | |
WO2003040312A3 (en) | Multifunctional green fluorescent protein and uses thereof | |
HK1089457A1 (en) | Recombinant igf expression systems | |
WO2003025182A1 (fr) | Adn de surexpression d'une hormone de croissance et utilisation | |
WO2003104449A3 (en) | IMPROVEMENTS IN PROTEIN PRODUCTION | |
AU2002234132A1 (en) | 13245, a novel human myotonic dystrophy type protein kinase and uses therefor | |
DE60124910D1 (de) | Menschliche twik-8 moleküle und ihre verwendung | |
WO2002070708A3 (en) | Glutamate receptor modulatory proteins and nucleic acids encoding them | |
DK0959130T3 (da) | Kloning og udtrykkelse af nyt glucoamylasegen fra Endomyces fibuliger | |
ATE386129T1 (de) | Produktion eukaryontischer proteine und nukleinsäuremoleküle in c. elegans | |
WO2002000709A3 (en) | Cerebellin homologous polypeptides and therapeutic uses thereof | |
WO2002016579A3 (en) | Nucleic acids, vectors, host cells, polypeptides and uses thereof | |
WO2003005958A3 (en) | Hypertension associated transcription factors and uses therefor |