ID26972A - TIOESTER ASAM S-SUBSTITUSI 11β-BENZALDOKSIN ESTRA-4,9-DIENAKARBONAT, PROSES UNTUK MEMBUAT DAN SEDIAAN FARMASI YANG TERDIRI DARI SENYAWA INI - Google Patents
TIOESTER ASAM S-SUBSTITUSI 11β-BENZALDOKSIN ESTRA-4,9-DIENAKARBONAT, PROSES UNTUK MEMBUAT DAN SEDIAAN FARMASI YANG TERDIRI DARI SENYAWA INIInfo
- Publication number
- ID26972A ID26972A IDW20001706A ID20001706A ID26972A ID 26972 A ID26972 A ID 26972A ID W20001706 A IDW20001706 A ID W20001706A ID 20001706 A ID20001706 A ID 20001706A ID 26972 A ID26972 A ID 26972A
- Authority
- ID
- Indonesia
- Prior art keywords
- estra
- tioester
- dienacarbonate
- benzaldoxins
- substitution
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 238000006467 substitution reaction Methods 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003862 glucocorticoid Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 102000003998 progesterone receptors Human genes 0.000 abstract 1
- 108090000468 progesterone receptors Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 150000007970 thio esters Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19809845A DE19809845A1 (de) | 1998-03-03 | 1998-03-03 | S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID26972A true ID26972A (id) | 2001-02-22 |
Family
ID=7860080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW20001706A ID26972A (id) | 1998-03-03 | 1999-02-10 | TIOESTER ASAM S-SUBSTITUSI 11β-BENZALDOKSIN ESTRA-4,9-DIENAKARBONAT, PROSES UNTUK MEMBUAT DAN SEDIAAN FARMASI YANG TERDIRI DARI SENYAWA INI |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6365582B1 (pl) |
| EP (1) | EP1060187B1 (pl) |
| JP (1) | JP3796405B2 (pl) |
| KR (1) | KR100488823B1 (pl) |
| CN (1) | CN1208341C (pl) |
| AT (1) | ATE237627T1 (pl) |
| AU (1) | AU749163B2 (pl) |
| BG (1) | BG64735B1 (pl) |
| BR (1) | BR9908458A (pl) |
| CA (1) | CA2322471C (pl) |
| CZ (1) | CZ20003125A3 (pl) |
| DE (2) | DE19809845A1 (pl) |
| DK (1) | DK1060187T3 (pl) |
| EA (1) | EA002766B1 (pl) |
| EE (1) | EE04242B1 (pl) |
| ES (1) | ES2197634T3 (pl) |
| HU (1) | HUP0100962A3 (pl) |
| ID (1) | ID26972A (pl) |
| IL (1) | IL137851A (pl) |
| IS (1) | IS5579A (pl) |
| NO (1) | NO316977B1 (pl) |
| NZ (1) | NZ506048A (pl) |
| PL (1) | PL193687B1 (pl) |
| PT (1) | PT1060187E (pl) |
| SK (1) | SK284177B6 (pl) |
| TR (1) | TR200002506T2 (pl) |
| UA (1) | UA59437C2 (pl) |
| WO (1) | WO1999045023A1 (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19906152B4 (de) | 1999-02-10 | 2005-02-10 | Jenapharm Gmbh & Co. Kg | Wirkstoffhaltige Laminate für Transdermalsysteme |
| BR0013710A (pt) * | 1999-08-31 | 2002-05-07 | Jenapharm Gmbh | Mesoprogestinas (moduladores de receptor para progesterona) como um componente de composições para a terapia de reposição de hormÈnios (hrt) |
| US8193252B1 (en) | 1999-08-31 | 2012-06-05 | Bayer Pharma AG | Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders |
| US7629334B1 (en) * | 1999-08-31 | 2009-12-08 | Bayer Schering Pharma Aktiengesellschaft | Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT) |
| UA77150C2 (en) * | 1999-08-31 | 2006-11-15 | Schering Ag | Use of mesoprogestins j867, j912, or j1042 for female contraception, pharmaceutical composition and kit (variants) |
| CA2382580C (en) * | 1999-08-31 | 2009-05-19 | Jenapharm Gmbh & Co. Kg | Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders |
| EP1285927A3 (de) * | 2001-08-16 | 2005-06-29 | Schering Aktiengesellschaft | Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems |
| DE10221034A1 (de) * | 2002-05-03 | 2003-11-20 | Schering Ag | 17alpha-Fluoralkyl-11ß-benzaldoxim-Steroide, Verfahren zu deren Herstellung, diese Steroide enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln |
| AU2003255355A1 (en) * | 2002-08-02 | 2004-02-25 | Schering Aktiengesellschaft | Progesterone receptor modulators having an increased antigonadotropic activity for use in female fertility testing and hormone replacement therapy |
| DE10236405A1 (de) * | 2002-08-02 | 2004-02-19 | Schering Ag | Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie |
| DE102005059222B4 (de) * | 2005-12-08 | 2007-10-11 | Bayer Schering Pharma Ag | 11ß-Benzaldoximderivate von D-Homoestra-4,9-dien-3-onen |
| HUE036870T2 (hu) | 2006-10-24 | 2018-08-28 | Repros Therapeutics Inc | Az endometriális proliferáció elnyomására szolgáló készítmények és módszerek |
| AU2008222829A1 (en) * | 2007-03-07 | 2008-09-12 | Janssen Pharmaceutica N.V. | Steroids derivatives as selective progesterone receptor modulators |
| TWI539953B (zh) | 2008-04-28 | 2016-07-01 | 瑞波若斯治療學公司 | 用於治療乳癌之組成物和方法 |
| DE102009034525A1 (de) * | 2009-07-21 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
| EP3865502A1 (en) | 2010-03-22 | 2021-08-18 | Allergan Pharmaceuticals International Limited | Compositions and methods for non-toxic delivery of cdb-2914 |
| EP2664325A1 (en) * | 2012-05-16 | 2013-11-20 | PregLem S.A. | Methods for preventing or treating androgen mediated diseases |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4039677A (en) * | 1976-03-01 | 1977-08-02 | Syntex (U.S.A.) Inc. | Novel 1-phenethylimidazoles |
| ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
| DE3504421A1 (de) * | 1985-02-07 | 1986-08-07 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue 11ss-phenyl-gonane, deren herstellung und diese enthaltende pharmazeutische praeparate |
| DE4332284C2 (de) * | 1993-09-20 | 1997-05-28 | Jenapharm Gmbh | 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE4332283A1 (de) * | 1993-09-20 | 1995-04-13 | Jenapharm Gmbh | Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US5576310A (en) * | 1994-09-20 | 1996-11-19 | Jenapharm Gmbh | 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds |
| IL115738A (en) | 1994-10-24 | 2002-05-23 | Schering Ag | Competitive progesterone antagonists for regulating female fertility as required |
| ZA9510926B (en) * | 1994-12-23 | 1996-07-03 | Schering Ag | Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception |
| KR100434238B1 (ko) | 1995-03-14 | 2004-07-16 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 경관팽창및신장조절을위한산화질소공여체또는산화질소억제제의용도 |
-
1998
- 1998-03-03 DE DE19809845A patent/DE19809845A1/de not_active Ceased
-
1999
- 1999-02-10 NZ NZ506048A patent/NZ506048A/en unknown
- 1999-02-10 JP JP2000534565A patent/JP3796405B2/ja not_active Expired - Fee Related
- 1999-02-10 TR TR2000/02506T patent/TR200002506T2/xx unknown
- 1999-02-10 PT PT99915475T patent/PT1060187E/pt unknown
- 1999-02-10 EE EEP200000500A patent/EE04242B1/xx not_active IP Right Cessation
- 1999-02-10 ID IDW20001706A patent/ID26972A/id unknown
- 1999-02-10 ES ES99915475T patent/ES2197634T3/es not_active Expired - Lifetime
- 1999-02-10 PL PL99342449A patent/PL193687B1/pl unknown
- 1999-02-10 BR BR9908458-9A patent/BR9908458A/pt not_active Application Discontinuation
- 1999-02-10 AU AU34067/99A patent/AU749163B2/en not_active Ceased
- 1999-02-10 HU HU0100962A patent/HUP0100962A3/hu unknown
- 1999-02-10 DK DK99915475T patent/DK1060187T3/da active
- 1999-02-10 EA EA200000896A patent/EA002766B1/ru not_active IP Right Cessation
- 1999-02-10 US US09/622,803 patent/US6365582B1/en not_active Expired - Fee Related
- 1999-02-10 WO PCT/DE1999/000408 patent/WO1999045023A1/de not_active Ceased
- 1999-02-10 CA CA002322471A patent/CA2322471C/en not_active Expired - Fee Related
- 1999-02-10 IL IL13785199A patent/IL137851A/xx not_active IP Right Cessation
- 1999-02-10 AT AT99915475T patent/ATE237627T1/de not_active IP Right Cessation
- 1999-02-10 SK SK1305-2000A patent/SK284177B6/sk unknown
- 1999-02-10 CZ CZ20003125A patent/CZ20003125A3/cs unknown
- 1999-02-10 EP EP99915475A patent/EP1060187B1/de not_active Expired - Lifetime
- 1999-02-10 DE DE59905075T patent/DE59905075D1/de not_active Expired - Fee Related
- 1999-02-10 KR KR10-2000-7009712A patent/KR100488823B1/ko not_active Expired - Fee Related
- 1999-02-10 CN CNB998036080A patent/CN1208341C/zh not_active Expired - Fee Related
- 1999-10-02 UA UA2000105635A patent/UA59437C2/uk unknown
-
2000
- 2000-07-28 IS IS5579A patent/IS5579A/is unknown
- 2000-08-28 BG BG104712A patent/BG64735B1/bg unknown
- 2000-09-01 NO NO20004362A patent/NO316977B1/no unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ID26972A (id) | TIOESTER ASAM S-SUBSTITUSI 11β-BENZALDOKSIN ESTRA-4,9-DIENAKARBONAT, PROSES UNTUK MEMBUAT DAN SEDIAAN FARMASI YANG TERDIRI DARI SENYAWA INI | |
| BRPI0510909A2 (pt) | composto de ligaÇço fÁrmaco-ligante citotàxico, formulaÇço farmacÊutica, mÉtodo para matar uma cÉlula e mÉtodo para retardar ou interromper o crescimento de tumor | |
| ATE454379T1 (de) | Benzothiazepin-derivate für die behandlung von hyperlipidemia | |
| CY1107438T1 (el) | Παραγωγα καρβοξυλικου οξεος, τα οποια παρεμποδιζουν την συνδεσιν ιντεγκρινων εις τους υποδοχεις των | |
| ATE308327T1 (de) | Verwendung von 2-hydroxy-5-phenylazobenzoesäure- derivaten als wirkstoffe zur chemoprävention und chemotherapie von kolonkrebs | |
| EA200500088A1 (ru) | Трициклические модуляторы ядерного рецептора стероидного гормона | |
| DE3819539A1 (de) | Inhibitoren von neutraler endopeptidase | |
| AU4831899A (en) | 5-HT1F agonists | |
| EP0244832A2 (de) | Ungesättigte Fettsäuren enthaltende Zubereitungen für die Synthese von Prostaglandinen und Hydroxyfettsäuren in biologischen Systemen | |
| IL146312A (en) | 3-(2-oxo-pyridinyl)-acylamino-propanoic acid derivatives that inhibit the binding of integrins to their receptors and pharmaceutical compositions comprising the same | |
| ID29025A (id) | Fenilalkenoilguanidina-fenilalkenoilguanidina yang disubstitusi asam empedu, proses pembuatannya, penggunaannya sebagai obat atau diaknostik dan obat-obat yang mengandungnya | |
| TR200504091T2 (tr) | (7alfa,17alfa)-17-hidroksi-7-metil-19-nor-17-pregn-5(10)-en 20-in-3-on içeren yüksek saflıkta bileşim. | |
| ATE222499T1 (de) | Pharmazeutische zusammensetzung enthaltend einen embryonalen extrakt und verfahren zu ihrer herstellung | |
| BR0308601A (pt) | inibidores de carboxipeptidase b de plasma | |
| HUP0105307A3 (en) | Acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as tace inhibitors and pharmaceutical compositions thereof and process for preparation the compounds | |
| Poras et al. | Modulation of disulfide dual ENKephalinase inhibitors (DENKIs) activity by a transient N-protection for pain alleviation by oral route | |
| EP1707560A4 (en) | HYDROXAMIC ACID DERIVATIVE AND THE DERIVATIVE INHIBITOR OF THE GENERATION OF AGE | |
| AR012341A1 (es) | Compuesto derivados de estradienos, composicion farmaceutica que los contiene y el uso de los mismos para la fabricacion de medicamentos | |
| AU2003208505A1 (en) | Process for preparation of a pharmaceutical composition containing acid labile compounds | |
| JPH0769883A (ja) | アロマターゼ阻害剤 | |
| DE59900775D1 (de) | Ungesättigte 14,15-cyclopropano-androstane, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische präparate | |
| WO2023288069A1 (en) | Methods of using substituted flavones for treating bone disorders | |
| DE50007708D1 (de) | Ungesättigte 14,15-cyclopropano-androstane, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen |