ID24356A - Proses pembuatan 1h-indol-3-glioksamida yang disubstitusi pada posisi 4 - Google Patents

Proses pembuatan 1h-indol-3-glioksamida yang disubstitusi pada posisi 4

Info

Publication number
ID24356A
ID24356A IDW991675A ID991675A ID24356A ID 24356 A ID24356 A ID 24356A ID W991675 A IDW991675 A ID W991675A ID 991675 A ID991675 A ID 991675A ID 24356 A ID24356 A ID 24356A
Authority
ID
Indonesia
Prior art keywords
glyoxamamide
indol
substituted
making
glyoxamamide substituted
Prior art date
Application number
IDW991675A
Other languages
English (en)
Indonesian (id)
Inventor
Vien Van Khau
Michael John Martinelli
Joseph Matthew Pawlak
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID24356A publication Critical patent/ID24356A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/14Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom with carbocyclic rings directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IDW991675A 1997-06-26 1998-06-22 Proses pembuatan 1h-indol-3-glioksamida yang disubstitusi pada posisi 4 ID24356A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5089197P 1997-06-26 1997-06-26
US5087797P 1997-06-26 1997-06-26

Publications (1)

Publication Number Publication Date
ID24356A true ID24356A (id) 2000-07-13

Family

ID=26728795

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW991675A ID24356A (id) 1997-06-26 1998-06-22 Proses pembuatan 1h-indol-3-glioksamida yang disubstitusi pada posisi 4

Country Status (24)

Country Link
US (1) US5986106A (es)
EP (1) EP0887342A3 (es)
JP (1) JP2002506460A (es)
KR (1) KR20010014167A (es)
CN (2) CN1268119A (es)
AR (1) AR013137A1 (es)
AU (1) AU735516B2 (es)
BR (1) BR9810481A (es)
CA (1) CA2293459A1 (es)
CO (1) CO4950517A1 (es)
EA (1) EA002119B1 (es)
EG (1) EG22077A (es)
HU (1) HUP0003019A3 (es)
ID (1) ID24356A (es)
IL (1) IL133624A0 (es)
NO (1) NO996432L (es)
NZ (1) NZ501780A (es)
PE (1) PE84199A1 (es)
PL (1) PL337690A1 (es)
TR (1) TR200000440T2 (es)
TW (1) TW455581B (es)
UA (1) UA56245C2 (es)
WO (1) WO1999000360A1 (es)
ZA (1) ZA985561B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3054399A (en) 1998-03-31 1999-10-25 Shionogi & Co., Ltd. Pyrrolo(1,2-a)pyrazine sPLA2 inhibitor
US6133453A (en) * 1998-05-15 2000-10-17 Pharm-Eco Laboratories, Inc. Method for making substituted indoles
CA2332528A1 (en) 1998-05-21 1999-11-25 Shionogi & Co., Ltd. Pyrrolo[1,2-b]pyridazine spla2 inhibitory
CA2346334A1 (en) * 1998-10-14 2000-04-20 Shionogi & Co., Ltd. Composition for treating or preventing ischemia reperfusion injury
US6380397B1 (en) * 1999-04-15 2002-04-30 Eli Lilly And Company Process for preparing 4-substituted-1H-indole-3-glyoxamides
DE19962300A1 (de) * 1999-12-23 2001-06-28 Asta Medica Ag Substituierte N-Benzyl-Indol-3-yl-glyoxylsäure-Derivate mit Antitumorwirkung
JPWO2002070477A1 (ja) * 2001-03-01 2004-07-02 小野薬品工業株式会社 2−メチルインドール−4−酢酸、その製造方法およびその合成中間体の製造方法
CN104292145A (zh) * 2014-10-12 2015-01-21 湖南华腾制药有限公司 一种6-溴吲哚衍生物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2145573A1 (de) * 1971-09-11 1973-03-15 Thiemann Chem Pharm Fab Indol-verbindungen, derivate derselben und verfahren zu ihrer herstellung
JPS55127367A (en) * 1979-03-23 1980-10-02 Shiono Koryo Kk Novel process for preparation of 4-(2-hydroxy-3- isopropylaminopropoxy)indole
RU2128169C1 (ru) * 1994-04-01 1999-03-27 Эли Лилли Энд Компани Iн-индол-3-глиоксиламиды, ингибирующие spla2-медиируемое выделение жирных кислот, фармацевтическая композиция
US5705501A (en) * 1994-11-17 1998-01-06 Molecular Geriatrics Corporation Certain substituted 1-aryl-3-morpholinopropanones to treat Alzheimer's Disease

Also Published As

Publication number Publication date
PE84199A1 (es) 1999-09-11
NZ501780A (en) 2002-08-28
AR013137A1 (es) 2000-12-13
TR200000440T2 (tr) 2000-07-21
CA2293459A1 (en) 1999-01-07
EA002119B1 (ru) 2001-12-24
EA200000069A1 (ru) 2000-06-26
US5986106A (en) 1999-11-16
NO996432D0 (no) 1999-12-23
JP2002506460A (ja) 2002-02-26
WO1999000360A1 (en) 1999-01-07
NO996432L (no) 2000-02-09
IL133624A0 (en) 2001-04-30
EP0887342A2 (en) 1998-12-30
HUP0003019A3 (en) 2001-02-28
ZA985561B (en) 2000-01-10
KR20010014167A (ko) 2001-02-26
AU7961398A (en) 1999-01-19
UA56245C2 (uk) 2003-05-15
PL337690A1 (en) 2000-08-28
AU735516B2 (en) 2001-07-12
BR9810481A (pt) 2000-09-12
CO4950517A1 (es) 2000-09-01
EG22077A (en) 2002-07-31
HUP0003019A2 (hu) 2001-01-29
EP0887342A3 (en) 1999-01-07
CN1343662A (zh) 2002-04-10
CN1268119A (zh) 2000-09-27
TW455581B (en) 2001-09-21

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ID24356A (id) Proses pembuatan 1h-indol-3-glioksamida yang disubstitusi pada posisi 4