ID23053A - Karboksamida yang digunakan sebagai agonis 5-ht <if> - Google Patents

Karboksamida yang digunakan sebagai agonis 5-ht <if>

Info

Publication number
ID23053A
ID23053A IDW991411A ID991411A ID23053A ID 23053 A ID23053 A ID 23053A ID W991411 A IDW991411 A ID W991411A ID 991411 A ID991411 A ID 991411A ID 23053 A ID23053 A ID 23053A
Authority
ID
Indonesia
Prior art keywords
agonist
carboxamide used
carboxamides
amino
carboxamide
Prior art date
Application number
IDW991411A
Other languages
English (en)
Indonesian (id)
Inventor
Michael Edward Flaugh
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID23053A publication Critical patent/ID23053A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyamides (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Organic Insulating Materials (AREA)
  • Conductive Materials (AREA)
  • Internal Circuitry In Semiconductor Integrated Circuit Devices (AREA)
  • Semiconductor Integrated Circuits (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IDW991411A 1997-06-04 1998-01-06 Karboksamida yang digunakan sebagai agonis 5-ht <if> ID23053A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4858497P 1997-06-04 1997-06-04

Publications (1)

Publication Number Publication Date
ID23053A true ID23053A (id) 2000-01-20

Family

ID=21955349

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW991411A ID23053A (id) 1997-06-04 1998-01-06 Karboksamida yang digunakan sebagai agonis 5-ht <if>

Country Status (21)

Country Link
EP (1) EP0882726B1 (ko)
JP (1) JP2002502419A (ko)
KR (1) KR20010013409A (ko)
CN (1) CN1259049A (ko)
AT (1) ATE240953T1 (ko)
AU (1) AU729786B2 (ko)
BR (1) BR9810610A (ko)
CA (1) CA2291624A1 (ko)
DE (1) DE69814735T2 (ko)
DK (1) DK0882726T3 (ko)
EA (1) EA001718B1 (ko)
ES (1) ES2199410T3 (ko)
HU (1) HUP0004142A3 (ko)
ID (1) ID23053A (ko)
IL (1) IL133279A0 (ko)
NO (1) NO995963L (ko)
NZ (1) NZ501569A (ko)
PL (1) PL337221A1 (ko)
PT (1) PT882726E (ko)
TR (1) TR199903014T2 (ko)
WO (1) WO1998055115A1 (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6608079B1 (en) 1998-12-11 2003-08-19 Eli Lilly And Company Indole derivatives and their use as 5-HT1F agonists
EP1184373A4 (en) 1999-04-20 2004-10-20 Meiji Seika Kaisha TRICYCLIC CONNECTIONS
NZ527771A (en) * 1999-08-04 2005-04-29 Icagen Inc Methods for treating or preventing anxiety
WO2001010380A2 (en) * 1999-08-04 2001-02-15 Icagen, Inc. Benzanilides as potassium channel openers
US6495550B2 (en) 1999-08-04 2002-12-17 Icagen, Inc. Pyridine-substituted benzanilides as potassium ion channel openers
TWI263497B (en) 2002-03-29 2006-10-11 Lilly Co Eli Pyridinoylpiperidines as 5-HT1F agonists
MXPA05011223A (es) 2003-04-18 2006-01-26 Lilly Co Eli Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas 5-htif.
UA82711C2 (en) 2003-09-12 2008-05-12 Эли Лилли Энд Компани Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists
EP1697305B1 (en) 2003-12-17 2007-08-15 Eli Lilly And Company Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-ht1f agonists
WO2007018168A1 (ja) * 2005-08-08 2007-02-15 Astellas Pharma Inc. アシルグアニジン誘導体またはその塩
US20100324017A1 (en) * 2007-02-07 2010-12-23 Isao Kinoyama Acylguanidine derivative
US8697869B2 (en) * 2010-03-22 2014-04-15 Actelion Pharmaceuticals Ltd. 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9H-carbazole derivatives and their use as prostaglandin D2 receptor modulators
WO2011123654A1 (en) 2010-04-02 2011-10-06 Colucid Pharmaceuticals, Inc. Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists
WO2014167327A1 (en) * 2013-04-09 2014-10-16 Cresset Biomolecular Discovery Ltd The treatment of inflammatory disorders
TWI776175B (zh) 2019-07-09 2022-09-01 美商美國禮來大藥廠 大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體,以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備
CN112125836A (zh) * 2020-10-15 2020-12-25 濮阳惠成电子材料股份有限公司 有机电致光电材料中间体n-苯基咔唑-3-羧酸乙酯的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226566D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
NZ305166A (en) * 1995-03-20 1998-12-23 Lilly Co Eli 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles; preparation and medicaments
EP0749962B1 (en) * 1995-06-23 2000-11-02 Eli Lilly And Company 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta(7,6-B)indoles

Also Published As

Publication number Publication date
EP0882726A1 (en) 1998-12-09
WO1998055115A1 (en) 1998-12-10
ES2199410T3 (es) 2004-02-16
DE69814735D1 (de) 2003-06-26
EA199901113A1 (ru) 2000-08-28
NZ501569A (en) 2001-11-30
NO995963D0 (no) 1999-12-03
PL337221A1 (en) 2000-08-14
HUP0004142A3 (en) 2002-10-28
NO995963L (no) 1999-12-03
DE69814735T2 (de) 2004-03-25
KR20010013409A (ko) 2001-02-26
CA2291624A1 (en) 1998-12-10
CN1259049A (zh) 2000-07-05
PT882726E (pt) 2003-09-30
AU729786B2 (en) 2001-02-08
AU7795598A (en) 1998-12-21
JP2002502419A (ja) 2002-01-22
TR199903014T2 (xx) 2000-05-22
IL133279A0 (en) 2001-04-30
EP0882726B1 (en) 2003-05-21
DK0882726T3 (da) 2003-09-22
ATE240953T1 (de) 2003-06-15
HUP0004142A2 (hu) 2001-05-28
EA001718B1 (ru) 2001-08-27
BR9810610A (pt) 2000-09-12

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