ID22073A - Turunan-turunan nitrometil tiobenzena sebagai bahan penghambat aldosa reduktase - Google Patents
Turunan-turunan nitrometil tiobenzena sebagai bahan penghambat aldosa reduktaseInfo
- Publication number
- ID22073A ID22073A IDW990564A ID990564A ID22073A ID 22073 A ID22073 A ID 22073A ID W990564 A IDW990564 A ID W990564A ID 990564 A ID990564 A ID 990564A ID 22073 A ID22073 A ID 22073A
- Authority
- ID
- Indonesia
- Prior art keywords
- tiobenzena
- nitromethy
- aldosa
- decreased
- reducing
- Prior art date
Links
- 230000000903 blocking effect Effects 0.000 title 1
- 230000003247 decreasing effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 102000016912 Aldehyde Reductase Human genes 0.000 abstract 1
- 108010053754 Aldehyde reductase Proteins 0.000 abstract 1
- 208000002177 Cataract Diseases 0.000 abstract 1
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- 206010012655 Diabetic complications Diseases 0.000 abstract 1
- 208000022873 Ocular disease Diseases 0.000 abstract 1
- 208000017442 Retinal disease Diseases 0.000 abstract 1
- 206010038923 Retinopathy Diseases 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
- C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
- C07C317/40—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
- C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
- C07C317/42—Y being a hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
- C07C323/49—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Furan Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9615887A FR2757509B1 (fr) | 1996-12-23 | 1996-12-23 | Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID22073A true ID22073A (id) | 1999-09-02 |
Family
ID=9499031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW990564A ID22073A (id) | 1996-12-23 | 1997-12-12 | Turunan-turunan nitrometil tiobenzena sebagai bahan penghambat aldosa reduktase |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US6509499B1 (es) |
| EP (1) | EP0946503B1 (es) |
| JP (1) | JP2001507001A (es) |
| KR (1) | KR20000069678A (es) |
| CN (1) | CN1112356C (es) |
| AT (1) | ATE215069T1 (es) |
| AU (1) | AU728562B2 (es) |
| BR (1) | BR9714069A (es) |
| CA (1) | CA2275665A1 (es) |
| CZ (1) | CZ227799A3 (es) |
| DE (1) | DE69711429T2 (es) |
| DK (1) | DK0946503T3 (es) |
| ES (1) | ES2172829T3 (es) |
| FR (1) | FR2757509B1 (es) |
| HU (1) | HUP0002054A3 (es) |
| ID (1) | ID22073A (es) |
| NO (1) | NO313325B1 (es) |
| PL (1) | PL334188A1 (es) |
| PT (1) | PT946503E (es) |
| RU (1) | RU2184110C2 (es) |
| SK (1) | SK282820B6 (es) |
| TR (1) | TR199901442T2 (es) |
| UA (1) | UA56205C2 (es) |
| WO (1) | WO1998028265A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2884820B1 (fr) * | 2005-04-25 | 2007-07-27 | Merck Sante Soc Par Actions Si | Nouveaux inhibiteurs specifiques de la caspase-10 |
| US8158667B2 (en) | 2006-08-21 | 2012-04-17 | Kador Peter F | Topical treatment of cataracts in dogs |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8718619D0 (en) * | 1987-08-06 | 1987-09-09 | Ici Plc | Pharmaceutical compositions |
| DE3835200A1 (de) * | 1988-10-15 | 1990-05-03 | Bayer Ag | Fluoralkyl-schwefel-arylverbindungen, deren verwendung, deren herstellung und vorprodukte zu deren herstellung |
| IE63463B1 (en) * | 1989-02-06 | 1995-04-19 | Zeneca Ltd | Phenylsulphone derivatives |
| US5120876A (en) * | 1989-11-29 | 1992-06-09 | E. I. Du Pont De Nemours And Company | Fluorinated sulfones/ketones for nonlinear optics |
| GB9016978D0 (en) | 1990-08-02 | 1990-09-19 | Ici Plc | Acetamide derivatives |
| US5250570A (en) | 1990-08-02 | 1993-10-05 | Imperial Chemical Industries Plc | Amidobenzene derivatives, compositions and use |
| GB9016980D0 (en) * | 1990-08-02 | 1990-09-19 | Ici Plc | Amidobenzenes |
| GB9016984D0 (en) | 1990-08-02 | 1990-09-19 | Ici Plc | Aniline derivatives |
-
1996
- 1996-12-23 FR FR9615887A patent/FR2757509B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-12 CZ CZ992277A patent/CZ227799A3/cs unknown
- 1997-12-12 AT AT97953797T patent/ATE215069T1/de not_active IP Right Cessation
- 1997-12-12 EP EP97953797A patent/EP0946503B1/fr not_active Expired - Lifetime
- 1997-12-12 AU AU57571/98A patent/AU728562B2/en not_active Ceased
- 1997-12-12 CA CA002275665A patent/CA2275665A1/en not_active Abandoned
- 1997-12-12 BR BR9714069-4A patent/BR9714069A/pt not_active IP Right Cessation
- 1997-12-12 PT PT97953797T patent/PT946503E/pt unknown
- 1997-12-12 DE DE69711429T patent/DE69711429T2/de not_active Expired - Fee Related
- 1997-12-12 US US09/331,662 patent/US6509499B1/en not_active Expired - Fee Related
- 1997-12-12 HU HU0002054A patent/HUP0002054A3/hu unknown
- 1997-12-12 PL PL97334188A patent/PL334188A1/xx unknown
- 1997-12-12 ES ES97953797T patent/ES2172829T3/es not_active Expired - Lifetime
- 1997-12-12 TR TR1999/01442T patent/TR199901442T2/xx unknown
- 1997-12-12 KR KR1019997005722A patent/KR20000069678A/ko not_active Ceased
- 1997-12-12 SK SK833-99A patent/SK282820B6/sk unknown
- 1997-12-12 JP JP52831998A patent/JP2001507001A/ja active Pending
- 1997-12-12 RU RU99115476/04A patent/RU2184110C2/ru not_active IP Right Cessation
- 1997-12-12 ID IDW990564A patent/ID22073A/id unknown
- 1997-12-12 DK DK97953797T patent/DK0946503T3/da active
- 1997-12-12 WO PCT/EP1997/006981 patent/WO1998028265A1/fr not_active Ceased
- 1997-12-12 CN CN97180948A patent/CN1112356C/zh not_active Expired - Fee Related
- 1997-12-12 UA UA99074125A patent/UA56205C2/uk unknown
-
1999
- 1999-06-22 NO NO19993082A patent/NO313325B1/no not_active IP Right Cessation
-
2002
- 2002-11-12 US US10/291,677 patent/US20030203966A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20000069678A (ko) | 2000-11-25 |
| JP2001507001A (ja) | 2001-05-29 |
| FR2757509A1 (fr) | 1998-06-26 |
| DE69711429D1 (en) | 2002-05-02 |
| FR2757509B1 (fr) | 1999-03-26 |
| SK282820B6 (sk) | 2002-12-03 |
| DE69711429T2 (de) | 2002-10-31 |
| WO1998028265A1 (fr) | 1998-07-02 |
| US20030203966A1 (en) | 2003-10-30 |
| UA56205C2 (uk) | 2003-05-15 |
| HUP0002054A3 (en) | 2002-09-30 |
| NO313325B1 (no) | 2002-09-16 |
| ES2172829T3 (es) | 2002-10-01 |
| PT946503E (pt) | 2002-09-30 |
| EP0946503A1 (fr) | 1999-10-06 |
| HUP0002054A2 (hu) | 2000-11-28 |
| CZ227799A3 (cs) | 1999-11-17 |
| NO993082L (no) | 1999-08-20 |
| ATE215069T1 (de) | 2002-04-15 |
| RU2184110C2 (ru) | 2002-06-27 |
| PL334188A1 (en) | 2000-02-14 |
| SK83399A3 (en) | 1999-12-10 |
| TR199901442T2 (xx) | 1999-09-21 |
| CA2275665A1 (en) | 1998-07-02 |
| AU5757198A (en) | 1998-07-17 |
| AU728562B2 (en) | 2001-01-11 |
| US6509499B1 (en) | 2003-01-21 |
| NO993082D0 (no) | 1999-06-22 |
| EP0946503B1 (fr) | 2002-03-27 |
| DK0946503T3 (da) | 2002-06-10 |
| BR9714069A (pt) | 2000-05-09 |
| CN1241997A (zh) | 2000-01-19 |
| CN1112356C (zh) | 2003-06-25 |
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