ID21577A - Komposisi-komposisi yang berguna untuk tranferase protein farnesil - Google Patents
Komposisi-komposisi yang berguna untuk tranferase protein farnesilInfo
- Publication number
- ID21577A ID21577A IDW990085A ID990085A ID21577A ID 21577 A ID21577 A ID 21577A ID W990085 A IDW990085 A ID W990085A ID 990085 A ID990085 A ID 990085A ID 21577 A ID21577 A ID 21577A
- Authority
- ID
- Indonesia
- Prior art keywords
- compositions use
- compounds
- farnesil
- tranferase
- protein tranferase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71329796A | 1996-09-13 | 1996-09-13 | |
| US87745397A | 1997-06-17 | 1997-06-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID21577A true ID21577A (id) | 1999-06-24 |
Family
ID=27108965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW990085A ID21577A (id) | 1996-09-13 | 1997-09-11 | Komposisi-komposisi yang berguna untuk tranferase protein farnesil |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0934303B1 (sk) |
| JP (1) | JP2001500515A (sk) |
| KR (1) | KR20000036110A (sk) |
| CN (1) | CN1237164A (sk) |
| AT (1) | ATE286044T1 (sk) |
| AU (1) | AU5196698A (sk) |
| BR (1) | BR9712980A (sk) |
| CA (1) | CA2266014A1 (sk) |
| CZ (1) | CZ84599A3 (sk) |
| DE (1) | DE69732123T2 (sk) |
| ES (1) | ES2234036T3 (sk) |
| ID (1) | ID21577A (sk) |
| IL (1) | IL128951A0 (sk) |
| NO (1) | NO991235L (sk) |
| NZ (1) | NZ334454A (sk) |
| PL (1) | PL332192A1 (sk) |
| SK (1) | SK33699A3 (sk) |
| TR (1) | TR199901275T2 (sk) |
| WO (1) | WO1998011091A2 (sk) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6524832B1 (en) | 1994-02-04 | 2003-02-25 | Arch Development Corporation | DNA damaging agents in combination with tyrosine kinase inhibitors |
| CA2293706C (en) * | 1997-06-17 | 2008-11-18 | Schering Corporation | N-substituted urea inhibitors of farnesyl-protein transferase |
| US5939416A (en) * | 1997-06-17 | 1999-08-17 | Schering Corporation | Benzo (5,6) cycloheptapyridine compounds useful as farnesyl protein transferase inhibitors |
| US6358968B1 (en) | 1997-06-17 | 2002-03-19 | Schering Corporation | N-substituted urea inhibitors of farnesyl-protein transferase |
| JP2002519427A (ja) | 1998-07-02 | 2002-07-02 | メルク エンド カムパニー インコーポレーテッド | プレニル蛋白トランスフェラーゼ阻害薬 |
| WO2000001382A1 (en) | 1998-07-02 | 2000-01-13 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| US6316462B1 (en) | 1999-04-09 | 2001-11-13 | Schering Corporation | Methods of inducing cancer cell death and tumor regression |
| WO2001051127A1 (en) | 2000-01-12 | 2001-07-19 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| AU2001229320A1 (en) | 2000-01-12 | 2001-07-24 | Merck And Co., Inc. | Inhibitors of prenyl-protein transferase |
| AU2001227757A1 (en) | 2000-01-12 | 2001-07-24 | Merck And Co., Inc. | Inhibitors of prenyl-protein transferase |
| WO2001077114A1 (en) | 2000-04-10 | 2001-10-18 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| KR920014799A (ko) * | 1991-01-18 | 1992-08-25 | 나오가따 다이도 | 신규벤조[5,6]시클로헵타[1,2-b]피리딘 유도체 및 이를 함유하는 항알레르기제 |
| ZA947969B (en) * | 1993-10-15 | 1996-07-12 | Schering Corp | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| ATE210652T1 (de) * | 1993-10-15 | 2001-12-15 | Schering Corp | Tricyclische carbamat-derivate zur inhibierung der g-protein funktion und für die behandlung von proliferativen erkrankungen |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| US5700806A (en) * | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| IL117798A (en) * | 1995-04-07 | 2001-11-25 | Schering Plough Corp | Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them |
| JP3193725B2 (ja) * | 1995-12-22 | 2001-07-30 | シェーリング コーポレイション | Ｇ―タンパク質機能の阻害および増殖性疾患の処置に有用な三環式アミド |
-
1997
- 1997-09-11 AT AT97946875T patent/ATE286044T1/de not_active IP Right Cessation
- 1997-09-11 CA CA002266014A patent/CA2266014A1/en not_active Abandoned
- 1997-09-11 TR TR1999/01275T patent/TR199901275T2/xx unknown
- 1997-09-11 JP JP10514032A patent/JP2001500515A/ja not_active Ceased
- 1997-09-11 IL IL12895197A patent/IL128951A0/xx unknown
- 1997-09-11 CZ CZ99845A patent/CZ84599A3/cs unknown
- 1997-09-11 PL PL97332192A patent/PL332192A1/xx unknown
- 1997-09-11 WO PCT/US1997/019976 patent/WO1998011091A2/en active IP Right Grant
- 1997-09-11 KR KR1019997002133A patent/KR20000036110A/ko not_active Application Discontinuation
- 1997-09-11 EP EP97946875A patent/EP0934303B1/en not_active Expired - Lifetime
- 1997-09-11 SK SK336-99A patent/SK33699A3/sk unknown
- 1997-09-11 AU AU51966/98A patent/AU5196698A/en not_active Abandoned
- 1997-09-11 CN CN97199597A patent/CN1237164A/zh active Pending
- 1997-09-11 BR BR9712980-1A patent/BR9712980A/pt unknown
- 1997-09-11 ES ES97946875T patent/ES2234036T3/es not_active Expired - Lifetime
- 1997-09-11 NZ NZ334454A patent/NZ334454A/xx unknown
- 1997-09-11 DE DE69732123T patent/DE69732123T2/de not_active Expired - Lifetime
- 1997-09-11 ID IDW990085A patent/ID21577A/id unknown
-
1999
- 1999-03-12 NO NO991235A patent/NO991235L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0934303A2 (en) | 1999-08-11 |
| NZ334454A (en) | 2000-08-25 |
| BR9712980A (pt) | 2000-04-18 |
| DE69732123D1 (de) | 2005-02-03 |
| DE69732123T2 (de) | 2005-12-08 |
| JP2001500515A (ja) | 2001-01-16 |
| SK33699A3 (en) | 2000-03-13 |
| IL128951A0 (en) | 2000-02-17 |
| ATE286044T1 (de) | 2005-01-15 |
| EP0934303B1 (en) | 2004-12-29 |
| CA2266014A1 (en) | 1998-03-19 |
| NO991235L (no) | 1999-05-10 |
| WO1998011091A2 (en) | 1998-03-19 |
| WO1998011091A3 (en) | 1998-06-11 |
| CZ84599A3 (cs) | 1999-07-14 |
| NO991235D0 (no) | 1999-03-12 |
| ES2234036T3 (es) | 2005-06-16 |
| PL332192A1 (en) | 1999-08-30 |
| AU5196698A (en) | 1998-04-02 |
| KR20000036110A (ko) | 2000-06-26 |
| CN1237164A (zh) | 1999-12-01 |
| TR199901275T2 (xx) | 1999-09-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL332242A1 (en) | Tricyclic inhibitors of proteinous farnesil transferase | |
| ID21577A (id) | Komposisi-komposisi yang berguna untuk tranferase protein farnesil | |
| ID22156A (id) | Turunan substitusi benzosikloheptapiridina yang berguna untuk menghambat fernesil protein transferase | |
| ID22067A (id) | Senyawa-senyawa yang berguna untuk inhibisi transferase protein farnesil | |
| ID22002A (id) | Derivatif benzosikloheptapiridin tersubstitusi yang berguna untuk penghalangan transferase protein farnesil |