ID21577A - Komposisi-komposisi yang berguna untuk tranferase protein farnesil - Google Patents
Komposisi-komposisi yang berguna untuk tranferase protein farnesilInfo
- Publication number
- ID21577A ID21577A IDW990085A ID990085A ID21577A ID 21577 A ID21577 A ID 21577A ID W990085 A IDW990085 A ID W990085A ID 990085 A ID990085 A ID 990085A ID 21577 A ID21577 A ID 21577A
- Authority
- ID
- Indonesia
- Prior art keywords
- compositions use
- compounds
- farnesil
- tranferase
- protein tranferase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71329796A | 1996-09-13 | 1996-09-13 | |
US87745397A | 1997-06-17 | 1997-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ID21577A true ID21577A (id) | 1999-06-24 |
Family
ID=27108965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW990085A ID21577A (id) | 1996-09-13 | 1997-09-11 | Komposisi-komposisi yang berguna untuk tranferase protein farnesil |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0934303B1 (ko) |
JP (1) | JP2001500515A (ko) |
KR (1) | KR20000036110A (ko) |
CN (1) | CN1237164A (ko) |
AT (1) | ATE286044T1 (ko) |
AU (1) | AU5196698A (ko) |
BR (1) | BR9712980A (ko) |
CA (1) | CA2266014A1 (ko) |
CZ (1) | CZ84599A3 (ko) |
DE (1) | DE69732123T2 (ko) |
ES (1) | ES2234036T3 (ko) |
ID (1) | ID21577A (ko) |
IL (1) | IL128951A0 (ko) |
NO (1) | NO991235L (ko) |
NZ (1) | NZ334454A (ko) |
PL (1) | PL332192A1 (ko) |
SK (1) | SK33699A3 (ko) |
TR (1) | TR199901275T2 (ko) |
WO (1) | WO1998011091A2 (ko) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6524832B1 (en) | 1994-02-04 | 2003-02-25 | Arch Development Corporation | DNA damaging agents in combination with tyrosine kinase inhibitors |
US6358968B1 (en) | 1997-06-17 | 2002-03-19 | Schering Corporation | N-substituted urea inhibitors of farnesyl-protein transferase |
US5939416A (en) * | 1997-06-17 | 1999-08-17 | Schering Corporation | Benzo (5,6) cycloheptapyridine compounds useful as farnesyl protein transferase inhibitors |
JP2002506444A (ja) * | 1997-06-17 | 2002-02-26 | シェーリング コーポレイション | ファルネシルタンパク質トランスフェラーゼの新規n置換尿素インヒビター |
US6410534B1 (en) | 1998-07-02 | 2002-06-25 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
WO2000001382A1 (en) | 1998-07-02 | 2000-01-13 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
US6316462B1 (en) | 1999-04-09 | 2001-11-13 | Schering Corporation | Methods of inducing cancer cell death and tumor regression |
AU2001229320A1 (en) | 2000-01-12 | 2001-07-24 | Merck And Co., Inc. | Inhibitors of prenyl-protein transferase |
US6350755B1 (en) | 2000-01-12 | 2002-02-26 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
WO2001051127A1 (en) | 2000-01-12 | 2001-07-19 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
AU2001251445A1 (en) | 2000-04-10 | 2001-10-23 | Merck And Co., Inc. | Inhibitors of prenyl-protein transferase |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
KR920014799A (ko) * | 1991-01-18 | 1992-08-25 | 나오가따 다이도 | 신규벤조[5,6]시클로헵타[1,2-b]피리딘 유도체 및 이를 함유하는 항알레르기제 |
US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
ES2164716T3 (es) * | 1993-10-15 | 2002-03-01 | Schering Corp | Compuestos triciclicos de carbamato utiles para inhibir la funcion de la proteina-g y para el tratamiento de enfermedades proliferativas. |
DE69429440T2 (de) * | 1993-10-15 | 2002-08-08 | Schering Corp | Tricyclische sulfonamide-derivate zur inhibierung der g-protein funktion und fur die bekandlung von proliferativen erkrantungen |
IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
US5700806A (en) * | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
IL117798A (en) * | 1995-04-07 | 2001-11-25 | Schering Plough Corp | Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them |
CA2240846C (en) * | 1995-12-22 | 2002-07-16 | Schering Corporation | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases |
-
1997
- 1997-09-11 IL IL12895197A patent/IL128951A0/xx unknown
- 1997-09-11 TR TR1999/01275T patent/TR199901275T2/xx unknown
- 1997-09-11 NZ NZ334454A patent/NZ334454A/xx unknown
- 1997-09-11 WO PCT/US1997/019976 patent/WO1998011091A2/en active IP Right Grant
- 1997-09-11 JP JP10514032A patent/JP2001500515A/ja not_active Ceased
- 1997-09-11 AT AT97946875T patent/ATE286044T1/de not_active IP Right Cessation
- 1997-09-11 KR KR1019997002133A patent/KR20000036110A/ko not_active Application Discontinuation
- 1997-09-11 BR BR9712980-1A patent/BR9712980A/pt unknown
- 1997-09-11 AU AU51966/98A patent/AU5196698A/en not_active Abandoned
- 1997-09-11 ID IDW990085A patent/ID21577A/id unknown
- 1997-09-11 PL PL97332192A patent/PL332192A1/xx unknown
- 1997-09-11 DE DE69732123T patent/DE69732123T2/de not_active Expired - Lifetime
- 1997-09-11 CZ CZ99845A patent/CZ84599A3/cs unknown
- 1997-09-11 ES ES97946875T patent/ES2234036T3/es not_active Expired - Lifetime
- 1997-09-11 SK SK336-99A patent/SK33699A3/sk unknown
- 1997-09-11 CA CA002266014A patent/CA2266014A1/en not_active Abandoned
- 1997-09-11 CN CN97199597A patent/CN1237164A/zh active Pending
- 1997-09-11 EP EP97946875A patent/EP0934303B1/en not_active Expired - Lifetime
-
1999
- 1999-03-12 NO NO991235A patent/NO991235L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ATE286044T1 (de) | 2005-01-15 |
DE69732123T2 (de) | 2005-12-08 |
IL128951A0 (en) | 2000-02-17 |
EP0934303A2 (en) | 1999-08-11 |
NO991235D0 (no) | 1999-03-12 |
PL332192A1 (en) | 1999-08-30 |
CN1237164A (zh) | 1999-12-01 |
WO1998011091A3 (en) | 1998-06-11 |
NZ334454A (en) | 2000-08-25 |
WO1998011091A2 (en) | 1998-03-19 |
SK33699A3 (en) | 2000-03-13 |
KR20000036110A (ko) | 2000-06-26 |
NO991235L (no) | 1999-05-10 |
CZ84599A3 (cs) | 1999-07-14 |
TR199901275T2 (xx) | 1999-09-21 |
AU5196698A (en) | 1998-04-02 |
BR9712980A (pt) | 2000-04-18 |
DE69732123D1 (de) | 2005-02-03 |
JP2001500515A (ja) | 2001-01-16 |
EP0934303B1 (en) | 2004-12-29 |
ES2234036T3 (es) | 2005-06-16 |
CA2266014A1 (en) | 1998-03-19 |
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