ID1037B - Eter isonitril dan senyawa-senyawa kompleks radioaktifnya - Google Patents

Eter isonitril dan senyawa-senyawa kompleks radioaktifnya

Info

Publication number
ID1037B
ID1037B IDP355186A ID863551A ID1037B ID 1037 B ID1037 B ID 1037B ID P355186 A IDP355186 A ID P355186A ID 863551 A ID863551 A ID 863551A ID 1037 B ID1037 B ID 1037B
Authority
ID
Indonesia
Prior art keywords
isonitril
eter
complex compounds
radioactive complex
radioactive
Prior art date
Application number
IDP355186A
Other languages
English (en)
Inventor
Paul Louis Bergstein
Vinayakam Subramanyam
Original Assignee
Dut Pont Merck Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27123612&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ID1037(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dut Pont Merck Pharmaceutical filed Critical Dut Pont Merck Pharmaceutical
Publication of ID1037B publication Critical patent/ID1037B/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/10—Isocyanides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Position Fixing By Use Of Radio Waves (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
IDP355186A 1985-12-23 1986-12-22 Eter isonitril dan senyawa-senyawa kompleks radioaktifnya ID1037B (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81247085A 1985-12-23 1985-12-23
US92509186A 1986-11-06 1986-11-06

Publications (1)

Publication Number Publication Date
ID1037B true ID1037B (id) 1996-10-24

Family

ID=27123612

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP355186A ID1037B (id) 1985-12-23 1986-12-22 Eter isonitril dan senyawa-senyawa kompleks radioaktifnya

Country Status (20)

Country Link
US (1) US4988827A (id)
EP (1) EP0233368B1 (id)
JP (2) JPH0755914B2 (id)
KR (1) KR940011456B1 (id)
CN (1) CN1057470C (id)
AU (1) AU594407B2 (id)
CA (1) CA1305160C (id)
DE (1) DE3673000D1 (id)
DK (1) DK173003B1 (id)
ES (1) ES2036171T3 (id)
FI (1) FI91747C (id)
GR (1) GR3000681T3 (id)
HU (1) HU201301B (id)
ID (1) ID1037B (id)
IE (1) IE59758B1 (id)
IL (1) IL81055A (id)
MX (1) MX168821B (id)
NO (1) NO166640C (id)
PT (1) PT83996B (id)
SU (1) SU1635903A3 (id)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5028699A (en) * 1987-09-11 1991-07-02 E. I. Du Pont De Nemours And Company Process for preparing Tc-99m tris(isonitrile) copper complexes
US4885100A (en) * 1987-09-11 1989-12-05 E. I. Du Pont De Nemours And Company Tris(isonitrile)copper(I) adducts for preparing radionuclide complexes
US5008418A (en) * 1987-09-11 1991-04-16 E. I. Du Pont De Nemours And Company Tris(isonitrile)copper(I) adducts for preparing radionuclide complexes
US4864051A (en) * 1988-09-02 1989-09-05 E. R. Squibb & Sons, Inc. Process for preparing 2-methoxyisobutylisonitrile
JPH05508162A (ja) * 1990-06-18 1993-11-18 マリンクロッド・メディカル・インコーポレイテッド イソニトリルリガンド含有金属―放射性核種錯化合物
US5210270A (en) * 1991-11-25 1993-05-11 Institute Of Nuclear Energy Research Method for synthesis and 99m C labelling of 2-alkoxyisobutylisonitrile
US5420321A (en) * 1993-08-03 1995-05-30 The Du Pont Merck Pharmaceutical Company Tris(isonitrile)copper(i) sulfates for preparing radionuclide complexes
DE4445004A1 (de) * 1994-12-16 1996-06-20 Consortium Elektrochem Ind Zusammensetzung zur delokalisierten Kennzeichnung von Gegenständen, ihre Herstellung und Verwendung
US5961952A (en) * 1996-01-24 1999-10-05 Dupont Pharmaceuticals Company 99m Tc-tertiary-butyl isonitrile as breast tumor imaging agents
US6416733B1 (en) 1996-10-07 2002-07-09 Bristol-Myers Squibb Pharma Company Radiopharmaceuticals for imaging infection and inflammation
US20030124053A1 (en) * 1996-10-07 2003-07-03 Barrett John Andrew Radiopharmaceuticals for imaging infection and inflammation
US6548663B1 (en) 1998-03-31 2003-04-15 Bristol-Myers Squibb Pharma Company Benzodiazepine vitronectin receptor antagonist pharmaceuticals
US6537520B1 (en) 1998-03-31 2003-03-25 Bristol-Myers Squibb Pharma Company Pharmaceuticals for the imaging of angiogenic disorders
US6524553B2 (en) * 1998-03-31 2003-02-25 Bristol-Myers Squibb Pharma Company Quinolone vitronectin receptor antagonist pharmaceuticals
CA2326978A1 (en) 1998-04-03 1999-10-14 Milind Rajopadhye Radiopharmaceuticals for imaging infection and inflammation and for imaging and treatment of cancer
AU2371400A (en) 1998-12-18 2000-07-03 Du Pont Pharmaceuticals Company Vitronectin receptor antagonist pharmaceuticals
CA2727746A1 (en) 1998-12-18 2000-06-22 Bristol-Myers Squibb Pharma Company Quinolone vitronectin receptor antagonist pharmaceuticals
US6794518B1 (en) 1998-12-18 2004-09-21 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
US6569402B1 (en) 1998-12-18 2003-05-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
US6511649B1 (en) * 1998-12-18 2003-01-28 Thomas D. Harris Vitronectin receptor antagonist pharmaceuticals
US6656448B1 (en) 2000-02-15 2003-12-02 Bristol-Myers Squibb Pharma Company Matrix metalloproteinase inhibitors
WO2001087354A2 (en) * 2000-05-17 2001-11-22 Bristol-Myers Squibb Pharma Company Use of small molecule radioligands for diagnostic imaging
BR0106717A (pt) * 2000-06-01 2002-04-16 Bristol Myers Squibb Pharma Co Compostos, composição farmacêutica e usos dos compostos de lactama inovadora
JP2004512382A (ja) * 2000-11-03 2004-04-22 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー 心臓灌流および心臓炎症の２核種同時イメージング
CN1136921C (zh) * 2001-04-27 2004-02-04 北京师范大学 一种心肌显像剂及其制备方法
US20090062256A1 (en) * 2001-06-01 2009-03-05 Bristol-Myers Squibb Pharma Company LACTAMS SUBSTITUTED BY CYCLIC SUCCINATES AS INHIBITORS OF Abeta PROTEIN PRODUCTION
JP2004537573A (ja) * 2001-08-08 2004-12-16 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー 心臓灌流およびビトロネクチン受容体を標的とするイメージング剤の同時イメージング
US6838074B2 (en) 2001-08-08 2005-01-04 Bristol-Myers Squibb Company Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
US20050106100A1 (en) * 2003-09-03 2005-05-19 Harris Thomas D. Compounds containing matrix metalloproteinase substrates and methods of their use
AU2006266074A1 (en) * 2005-06-30 2007-01-11 Bristol-Myers Squibb Pharma Company Hydrazide conjugates as imaging agents
US20110236308A1 (en) * 2006-04-19 2011-09-29 The General Hospital Corporation Aryl Bidentate Isonitriles and Their Uses
US7563920B2 (en) 2006-10-30 2009-07-21 Draximage Limited Methods for preparing 2-methoxyisobutylisonitrile and tetrakis(2-methoxyisobutylisonitrile)copper(I) tetrafluoroborate
EP2821394A1 (en) * 2013-07-01 2015-01-07 Fundacion MEDINA. Centro de Excelencia en Investigacion de Medicamentos Innovadores en Andalucia Compounds with antibacterial activity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1215142B (de) * 1964-07-09 1966-04-28 Bayer Ag Verfahren zur Herstellung von araliphatischen Isonitrilen
GB1187755A (en) * 1968-02-24 1970-04-15 Bayer Ag A Process for the Production of Isonitriles
DE1962898A1 (de) * 1969-12-16 1971-06-24 Bayer Ag Verfahren zur Herstellung von Isonitrilen
JPS57165370A (en) * 1981-03-18 1982-10-12 Ici Ltd Triazole or imidazole compounds, manufacture and fungicidal or plant growth regulant agent
US4347251A (en) * 1981-07-13 1982-08-31 American Cyanamid Company Novel 3-substituted amino-1-substituted heteroaryl-2-pyrazolines
US4452774A (en) * 1982-04-30 1984-06-05 President And Fellows Of Harvard College Isonitrile radionuclide complexes for labelling and imaging agents
DE3343673A1 (de) * 1983-12-02 1985-09-05 Basf Ag, 6700 Ludwigshafen Verfahren zur gleichzeitigen herstellung von nitrilen und acrylamid bzw. methacrylamid
US4707544A (en) * 1984-11-28 1987-11-17 President And Fellows Of Harvard College Metal-isonitrile adducts for preparing radionuclide complexes for labelling and imaging agents
US4735793A (en) * 1985-08-30 1988-04-05 Massachusetts Institute Of Technology Carboxy, carboalkoxy and carbamile substituted isonitrile radionuclide complexes

Also Published As

Publication number Publication date
US4988827A (en) 1991-01-29
DK623886D0 (da) 1986-12-22
NO166640C (no) 1991-08-21
NO865247L (no) 1987-06-24
HUT43557A (en) 1987-11-30
GR3000681T3 (en) 1991-09-27
FI865260A (fi) 1987-06-24
JP2774940B2 (ja) 1998-07-09
HU201301B (en) 1990-10-28
CN1057585A (zh) 1992-01-08
CN1057470C (zh) 2000-10-18
FI865260A0 (fi) 1986-12-22
MX168821B (es) 1993-06-10
FI91747C (fi) 1994-08-10
KR870005976A (ko) 1987-07-08
KR940011456B1 (ko) 1994-12-15
CA1305160C (en) 1992-07-14
IE863353L (en) 1987-06-23
JPH07242615A (ja) 1995-09-19
DK173003B1 (da) 1999-11-01
DE3673000D1 (de) 1990-08-30
AU6684286A (en) 1987-06-25
JPS62201363A (ja) 1987-09-05
IE59758B1 (en) 1994-03-23
FI91747B (fi) 1994-04-29
DK623886A (da) 1987-06-24
SU1635903A3 (ru) 1991-03-15
ES2036171T3 (es) 1996-07-16
PT83996B (pt) 1989-07-31
IL81055A (en) 1991-07-18
EP0233368A1 (en) 1987-08-26
EP0233368B1 (en) 1990-07-25
IL81055A0 (en) 1987-03-31
NO865247D0 (no) 1986-12-22
PT83996A (en) 1987-01-01
NO166640B (no) 1991-05-13
JPH0755914B2 (ja) 1995-06-14
AU594407B2 (en) 1990-03-08

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