HUT67325A - New selective aromatase inhibiting 4(5)-imidazoles and pharmaceutical compositions containing them - Google Patents

New selective aromatase inhibiting 4(5)-imidazoles and pharmaceutical compositions containing them

Info

Publication number
HUT67325A
HUT67325A HU9303653A HU9303653A HUT67325A HU T67325 A HUT67325 A HU T67325A HU 9303653 A HU9303653 A HU 9303653A HU 9303653 A HU9303653 A HU 9303653A HU T67325 A HUT67325 A HU T67325A
Authority
HU
Hungary
Prior art keywords
imidazoles
pharmaceutical compositions
compositions containing
aromatase inhibiting
new selective
Prior art date
Application number
HU9303653A
Other languages
English (en)
Other versions
HU9303653D0 (en
Inventor
Arto Johannes Karjalainen
Arja Marketta Kalapudas
Marja-Liisa Soedervall
Risto Arvo Sakari Lammintausta
Reino Olavi Pelkonen
Jarmo Sakari Salonen
Aire Marja Laine
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919113142A external-priority patent/GB9113142D0/en
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of HU9303653D0 publication Critical patent/HU9303653D0/hu
Publication of HUT67325A publication Critical patent/HUT67325A/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU9303653A 1991-06-18 1993-12-17 New selective aromatase inhibiting 4(5)-imidazoles and pharmaceutical compositions containing them HUT67325A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919113142A GB9113142D0 (en) 1991-06-18 1991-06-18 New selective aromatase inhibiting 4(5)-imidazoles
GB919125924A GB9125924D0 (en) 1991-06-18 1991-12-05 Stereoisomers of an imidazole derivative

Publications (2)

Publication Number Publication Date
HU9303653D0 HU9303653D0 (en) 1994-04-28
HUT67325A true HUT67325A (en) 1995-03-28

Family

ID=26299089

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9303653A HUT67325A (en) 1991-06-18 1993-12-17 New selective aromatase inhibiting 4(5)-imidazoles and pharmaceutical compositions containing them

Country Status (25)

Country Link
US (1) US5559141A (hu)
EP (1) EP0589975A1 (hu)
JP (1) JPH06508119A (hu)
KR (1) KR940701386A (hu)
CN (1) CN1068819A (hu)
AU (1) AU665002B2 (hu)
BG (1) BG98306A (hu)
CA (1) CA2111469A1 (hu)
CZ (1) CZ280293A3 (hu)
FI (1) FI935658A0 (hu)
GB (1) GB9125924D0 (hu)
HR (1) HRP920170A2 (hu)
HU (1) HUT67325A (hu)
IE (1) IE921963A1 (hu)
IL (2) IL102216A (hu)
LT (1) LT3164B (hu)
LV (1) LV10093B (hu)
MX (1) MX9203000A (hu)
NO (1) NO934688D0 (hu)
NZ (1) NZ243139A (hu)
PT (1) PT100604A (hu)
SI (1) SI9200113A (hu)
SK (1) SK144393A3 (hu)
TW (1) TW206217B (hu)
WO (1) WO1992022537A1 (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2273704B (en) * 1992-12-16 1997-01-22 Orion Yhtymae Oy Triazolyl diaryl selective aromatase inhibiting compounds
SE9302333D0 (sv) * 1993-07-06 1993-07-06 Ab Astra New compounds
CA2250231A1 (en) * 1996-04-03 1997-10-09 Robert P. Gomez Inhibitors of farnesyl-protein transferase
US6063930A (en) * 1996-04-03 2000-05-16 Merck & Co., Inc. Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6080870A (en) * 1996-04-03 2000-06-27 Merck & Co., Inc. Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6297239B1 (en) * 1997-10-08 2001-10-02 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
KR20030031132A (ko) 2000-07-28 2003-04-18 스미또모 세이야꾸 가부시키가이샤 피롤 유도체
EP1680109A4 (en) 2003-10-07 2009-05-06 Renovis Inc AMIDE DERIVATIVES AS ION CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE DERIVATIVES
US20080300243A1 (en) * 2005-02-28 2008-12-04 Kelly Michael G Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same
US7576099B2 (en) 2005-02-28 2009-08-18 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
US7902247B2 (en) * 2008-01-09 2011-03-08 Allergan, Inc. Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605661A (en) * 1984-06-18 1986-08-12 Eli Lilly And Company Aromastase inhibiting α,α-diarylimidazole-4(5)-propionitriles, α,α-diarylimidazole-4(5)-propionamides, and 4(5)-(2,2-diarylethyl)imidazoles
GB2210875B (en) * 1987-10-09 1991-05-29 Farmos Oy Aromatase inhibiting 4(5)-imidazoles
GB2248058B (en) * 1990-09-21 1994-09-14 Orion Yhtymae Oy Aromatase inhibiting 4(5)-imidazoles
AU627559B2 (en) * 1989-03-30 1992-08-27 Farmos-Yhtyma Oy Novel aromatase inhibiting 4(5)-imidazoles
US5439928A (en) * 1989-03-30 1995-08-08 Orion-Yhtyma Oy Aromatase inhibiting 4(5)-imidazoles

Also Published As

Publication number Publication date
SI9200113A (en) 1992-12-31
JPH06508119A (ja) 1994-09-14
FI935658A (fi) 1993-12-16
CN1068819A (zh) 1993-02-10
TW206217B (hu) 1993-05-21
LT3164B (en) 1995-02-27
EP0589975A1 (en) 1994-04-06
AU1978392A (en) 1993-01-12
AU665002B2 (en) 1995-12-14
CA2111469A1 (en) 1992-12-23
IE921963A1 (en) 1992-12-30
SK144393A3 (en) 1994-11-09
IL115439A0 (en) 1995-12-31
NO934688L (no) 1993-12-17
NZ243139A (en) 1994-08-26
FI935658A0 (fi) 1993-12-16
KR940701386A (ko) 1994-05-28
IL102216A0 (en) 1993-01-14
GB9125924D0 (en) 1992-02-05
WO1992022537A1 (en) 1992-12-23
NO934688D0 (no) 1993-12-17
HU9303653D0 (en) 1994-04-28
LV10093B (en) 1995-02-20
BG98306A (bg) 1994-08-30
CZ280293A3 (en) 1994-05-18
US5559141A (en) 1996-09-24
MX9203000A (es) 1993-02-01
LV10093A (lv) 1994-05-10
LTIP175A (lt) 1994-08-25
HRP920170A2 (en) 1994-08-31
IL102216A (en) 1996-06-18
PT100604A (pt) 1993-10-29

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Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee
DNF4 Restoration of lapsed final protection
DFD9 Temporary protection cancelled due to non-payment of fee