HUT53675A - Process for producing insulin preproduct in streptomycetes - Google Patents
Process for producing insulin preproduct in streptomycetesInfo
- Publication number
- HUT53675A HUT53675A HU895649A HU564989A HUT53675A HU T53675 A HUT53675 A HU T53675A HU 895649 A HU895649 A HU 895649A HU 564989 A HU564989 A HU 564989A HU T53675 A HUT53675 A HU T53675A
- Authority
- HU
- Hungary
- Prior art keywords
- streptomycetes
- preproduct
- lys
- gene
- producing insulin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3837273A DE3837273A1 (de) | 1987-05-05 | 1988-11-03 | Verfahren zur herstellung eines insulin-vorprodukts in streptomyceten |
DE19893927449 DE3927449A1 (de) | 1989-08-19 | 1989-08-19 | Verfahren zur herstellung eines insulin-vorprodukts in streptomyceten |
Publications (3)
Publication Number | Publication Date |
---|---|
HU895649D0 HU895649D0 (en) | 1990-01-28 |
HUT53675A true HUT53675A (en) | 1990-11-28 |
HU209596B HU209596B (en) | 1994-08-29 |
Family
ID=25873834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU895649A HU209596B (en) | 1988-11-03 | 1989-11-02 | Process for producing of insuline pro-product in streptomyceten |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0367163B1 (hu) |
JP (1) | JPH02219588A (hu) |
KR (1) | KR900008040A (hu) |
CN (1) | CN1042378A (hu) |
AT (1) | ATE132531T1 (hu) |
AU (1) | AU619054B2 (hu) |
CA (1) | CA2002062A1 (hu) |
DE (1) | DE58909556D1 (hu) |
DK (1) | DK546889A (hu) |
ES (1) | ES2081826T3 (hu) |
FI (1) | FI95600C (hu) |
GR (1) | GR3018738T3 (hu) |
HU (1) | HU209596B (hu) |
IE (1) | IE893530L (hu) |
IL (1) | IL92178A (hu) |
NO (1) | NO894363L (hu) |
NZ (1) | NZ231222A (hu) |
PT (1) | PT92177B (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3714866A1 (de) * | 1987-05-05 | 1988-11-24 | Hoechst Ag | Verfahren zur herstellung von fremdproteinen in streptomyceten |
DE4012818A1 (de) * | 1990-04-21 | 1991-10-24 | Hoechst Ag | Verfahren zur herstellung von fremdproteinen in streptomyceten |
US5426036A (en) * | 1987-05-05 | 1995-06-20 | Hoechst Aktiengesellschaft | Processes for the preparation of foreign proteins in streptomycetes |
KR100188800B1 (ko) | 1990-09-05 | 1999-06-01 | 이센브룩, 라피세 | 프리프로인슐린을 인슐린으로 전환시키기 위한 효소적 방법 |
GB9513967D0 (en) * | 1995-07-08 | 1995-09-06 | Univ Leicester | Insulin |
RU2458989C1 (ru) | 2008-08-07 | 2012-08-20 | Байокон Лимитид | Способ получения аналогов инсулина из их соответствующих предшественников (варианты) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3418274A1 (de) * | 1984-05-17 | 1985-11-21 | Hoechst Ag, 6230 Frankfurt | Signalpeptid fuer die exkretion von peptiden in streptomyceten |
DK129385A (da) * | 1985-03-22 | 1986-09-23 | Novo Industri As | Peptider og fremstilling deraf |
DK437786D0 (da) * | 1986-09-12 | 1986-09-12 | Nordisk Gentofte | Insulinprecursorer |
DE3707150A1 (de) * | 1987-03-06 | 1988-09-15 | Hoechst Ag | Tendamistat-derivate |
DE3714866A1 (de) * | 1987-05-05 | 1988-11-24 | Hoechst Ag | Verfahren zur herstellung von fremdproteinen in streptomyceten |
-
1989
- 1989-10-28 EP EP89120056A patent/EP0367163B1/de not_active Expired - Lifetime
- 1989-10-28 DE DE58909556T patent/DE58909556D1/de not_active Expired - Fee Related
- 1989-10-28 ES ES89120056T patent/ES2081826T3/es not_active Expired - Lifetime
- 1989-10-28 AT AT89120056T patent/ATE132531T1/de not_active IP Right Cessation
- 1989-11-01 FI FI895184A patent/FI95600C/fi not_active IP Right Cessation
- 1989-11-01 IL IL9217889A patent/IL92178A/en not_active IP Right Cessation
- 1989-11-01 NZ NZ231222A patent/NZ231222A/xx unknown
- 1989-11-01 AU AU43950/89A patent/AU619054B2/en not_active Ceased
- 1989-11-02 NO NO89894363A patent/NO894363L/no unknown
- 1989-11-02 KR KR1019890015844A patent/KR900008040A/ko active IP Right Grant
- 1989-11-02 HU HU895649A patent/HU209596B/hu not_active IP Right Cessation
- 1989-11-02 IE IE893530A patent/IE893530L/xx unknown
- 1989-11-02 CA CA002002062A patent/CA2002062A1/en not_active Abandoned
- 1989-11-02 PT PT92177A patent/PT92177B/pt not_active IP Right Cessation
- 1989-11-02 JP JP1287282A patent/JPH02219588A/ja active Pending
- 1989-11-02 DK DK546889A patent/DK546889A/da not_active Application Discontinuation
- 1989-11-03 CN CN89108320A patent/CN1042378A/zh active Pending
-
1996
- 1996-01-19 GR GR960400123T patent/GR3018738T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN1042378A (zh) | 1990-05-23 |
EP0367163B1 (de) | 1996-01-03 |
HU895649D0 (en) | 1990-01-28 |
JPH02219588A (ja) | 1990-09-03 |
NO894363L (no) | 1990-05-04 |
GR3018738T3 (en) | 1996-04-30 |
DK546889D0 (da) | 1989-11-02 |
ES2081826T3 (es) | 1996-03-16 |
AU619054B2 (en) | 1992-01-16 |
KR900008040A (ko) | 1990-06-02 |
FI95600B (fi) | 1995-11-15 |
EP0367163A3 (de) | 1991-03-06 |
EP0367163A2 (de) | 1990-05-09 |
NZ231222A (en) | 1991-08-27 |
DK546889A (da) | 1990-05-04 |
IL92178A (en) | 1995-11-27 |
IL92178A0 (en) | 1990-07-26 |
HU209596B (en) | 1994-08-29 |
PT92177B (pt) | 1995-06-30 |
CA2002062A1 (en) | 1990-05-03 |
NO894363D0 (no) | 1989-11-02 |
IE893530L (en) | 1990-05-03 |
AU4395089A (en) | 1990-05-10 |
ATE132531T1 (de) | 1996-01-15 |
FI895184A0 (fi) | 1989-11-01 |
DE58909556D1 (de) | 1996-02-15 |
FI95600C (fi) | 1996-02-26 |
PT92177A (pt) | 1990-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HMM4 | Cancellation of final prot. due to non-payment of fee |