HUT43815A - Process for producing new pirrolidine derivatives and pharmaceutical compositions containing the new compounds - Google Patents
Process for producing new pirrolidine derivatives and pharmaceutical compositions containing the new compoundsInfo
- Publication number
- HUT43815A HUT43815A HU862609A HU260986A HUT43815A HU T43815 A HUT43815 A HU T43815A HU 862609 A HU862609 A HU 862609A HU 260986 A HU260986 A HU 260986A HU T43815 A HUT43815 A HU T43815A
- Authority
- HU
- Hungary
- Prior art keywords
- new
- pharmaceutical compositions
- compositions containing
- producing
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21234/85A IT1190378B (it) | 1985-06-21 | 1985-06-21 | Derivati pirrolidonici |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT43815A true HUT43815A (en) | 1987-12-28 |
| HU196225B HU196225B (en) | 1988-10-28 |
Family
ID=11178795
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU862609A HU196225B (en) | 1985-06-21 | 1986-06-20 | Process for producing new pirrolidine derivatives and pharmaceutical compositions containing the new compounds |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4824861A (hu) |
| EP (1) | EP0207681B1 (hu) |
| JP (1) | JPS62461A (hu) |
| KR (1) | KR930006766B1 (hu) |
| AT (1) | ATE73821T1 (hu) |
| AU (1) | AU587258B2 (hu) |
| CA (1) | CA1284248C (hu) |
| DE (1) | DE3684368D1 (hu) |
| DK (1) | DK290286A (hu) |
| ES (2) | ES8800164A1 (hu) |
| FI (1) | FI82446C (hu) |
| GR (1) | GR861577B (hu) |
| HU (1) | HU196225B (hu) |
| IL (1) | IL79136A (hu) |
| IT (1) | IT1190378B (hu) |
| NO (1) | NO168428C (hu) |
| NZ (1) | NZ216550A (hu) |
| PH (1) | PH22851A (hu) |
| PT (2) | PT82813B (hu) |
| ZA (1) | ZA864444B (hu) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1209644B (it) * | 1985-06-21 | 1989-08-30 | Isf Spa | Composti farmacologicamente attivi. |
| DK356288A (da) * | 1987-07-30 | 1989-01-31 | Lonza Ag | Fremgangsmaade til fremstilling af n-((4-hydroxy-pyrrolidin-2-on-1-yl)-acetyl)-glycinamid |
| IL93051A0 (en) * | 1989-01-17 | 1990-11-05 | Hoffmann La Roche | ((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing them |
| CH680293A5 (hu) * | 1990-06-26 | 1992-07-31 | Lonza Ag | |
| US6229011B1 (en) * | 1997-08-22 | 2001-05-08 | Hoffman-La Roche Inc. | N-aroylphenylalanine derivative VCAM-1 inhibitors |
| ID30057A (id) | 1999-02-18 | 2001-11-01 | Hoffmann La Roche | Turunan fenilalaninol |
| HUP0200155A3 (en) | 1999-02-18 | 2005-04-28 | Hoffmann La Roche | Thioamide derivatives, pharmaceutical compositions containing them and their use |
| WO2009145839A1 (en) * | 2008-04-04 | 2009-12-03 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Polyamine compounds that bind tar rna of hiv and methods of treating viral disorders |
| CN101914052B (zh) * | 2010-08-02 | 2012-06-27 | 胡建荣 | 一种奥拉西坦化合物的制备方法 |
| CN102351770B (zh) * | 2011-08-12 | 2012-07-04 | 江西新先锋医药有限公司 | 一种奥拉西坦化合物及其药物组合物 |
| CN112724062B (zh) * | 2021-01-19 | 2022-03-15 | 江苏诚信药业有限公司 | 一种奥拉西坦杂质b的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH470396A (de) * | 1963-08-12 | 1969-03-31 | Hoffmann La Roche | Verfahren zur Herstellung von 4-Imidazolidon-Verbindungen |
| IT1045043B (it) * | 1975-08-13 | 1980-04-21 | Isf Spa | Derivati pirrolidinici |
| AT360980B (de) * | 1976-01-14 | 1981-02-10 | Pliva Pharm & Chem Works | Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins |
| YU39660B (en) * | 1976-01-14 | 1985-03-20 | Pliva Pharm & Chem Works | Process for obtaining 2-oxo-1-pyrrolidine acetamide |
| GB1539817A (en) * | 1976-10-22 | 1979-02-07 | Ucb Sa | N-substituted lactams |
| IT1075564B (it) * | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| IT1141287B (it) * | 1979-06-13 | 1986-10-01 | Nattermann A & Cie | Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono |
| FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
| EP0115473A3 (de) * | 1983-01-27 | 1987-01-21 | Ciba-Geigy Ag | Substituierte Pyrrolidinonderivate und Verfahren zu ihrer Herstellung |
| IT1209644B (it) * | 1985-06-21 | 1989-08-30 | Isf Spa | Composti farmacologicamente attivi. |
| JPH0681502B2 (ja) * | 1988-07-14 | 1994-10-12 | 富士通電装株式会社 | 並列運転保護回路 |
-
1985
- 1985-06-21 IT IT21234/85A patent/IT1190378B/it active
-
1986
- 1986-06-06 FI FI862420A patent/FI82446C/fi not_active IP Right Cessation
- 1986-06-13 ZA ZA864444A patent/ZA864444B/xx unknown
- 1986-06-16 NZ NZ216550A patent/NZ216550A/xx unknown
- 1986-06-17 EP EP86304653A patent/EP0207681B1/en not_active Expired - Lifetime
- 1986-06-17 AT AT86304653T patent/ATE73821T1/de not_active IP Right Cessation
- 1986-06-17 DE DE8686304653T patent/DE3684368D1/de not_active Expired - Lifetime
- 1986-06-17 IL IL79136A patent/IL79136A/xx unknown
- 1986-06-18 GR GR861577A patent/GR861577B/el unknown
- 1986-06-20 PT PT82813A patent/PT82813B/pt not_active IP Right Cessation
- 1986-06-20 HU HU862609A patent/HU196225B/hu not_active IP Right Cessation
- 1986-06-20 JP JP61144686A patent/JPS62461A/ja active Pending
- 1986-06-20 PH PH33922A patent/PH22851A/en unknown
- 1986-06-20 ES ES556353A patent/ES8800164A1/es not_active Expired
- 1986-06-20 KR KR1019860004920A patent/KR930006766B1/ko active IP Right Grant
- 1986-06-20 AU AU58919/86A patent/AU587258B2/en not_active Ceased
- 1986-06-20 NO NO862486A patent/NO168428C/no unknown
- 1986-06-20 CA CA000512114A patent/CA1284248C/en not_active Expired - Fee Related
- 1986-06-20 ES ES556351A patent/ES8801201A1/es not_active Expired
- 1986-06-20 PT PT82815A patent/PT82815B/pt not_active IP Right Cessation
- 1986-06-20 DK DK290286A patent/DK290286A/da not_active Application Discontinuation
-
1987
- 1987-12-11 US US07/131,862 patent/US4824861A/en not_active Expired - Lifetime
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |