HUT40436A - Process for production pirrolo-benzimidasoles and medical preparatives containing thereof - Google Patents
Process for production pirrolo-benzimidasoles and medical preparatives containing thereofInfo
- Publication number
- HUT40436A HUT40436A HU854775A HU477585A HUT40436A HU T40436 A HUT40436 A HU T40436A HU 854775 A HU854775 A HU 854775A HU 477585 A HU477585 A HU 477585A HU T40436 A HUT40436 A HU T40436A
- Authority
- HU
- Hungary
- Prior art keywords
- benzimidasoles
- pirrolo
- production
- preparatives containing
- medical preparatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- BKOVMXWXILSWCU-UHFFFAOYSA-N pyrrolo[3,2-e]benzimidazole Chemical class C1=CC2=NC=CC2=C2N=CN=C21 BKOVMXWXILSWCU-UHFFFAOYSA-N 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843445669 DE3445669A1 (de) | 1984-12-14 | 1984-12-14 | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT40436A true HUT40436A (en) | 1986-12-28 |
| HU194241B HU194241B (en) | 1988-01-28 |
Family
ID=6252801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU854775A HU194241B (en) | 1984-12-14 | 1985-12-13 | Process for production pirrolo-benzimidasoles and medical preparatives containing thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US4710510A (hu) |
| EP (1) | EP0186010B1 (hu) |
| JP (1) | JPS61158984A (hu) |
| AT (1) | ATE49970T1 (hu) |
| AU (1) | AU580822B2 (hu) |
| CA (1) | CA1262908A (hu) |
| CS (1) | CS276403B6 (hu) |
| DD (1) | DD242045A5 (hu) |
| DE (2) | DE3445669A1 (hu) |
| DK (1) | DK579185A (hu) |
| ES (1) | ES8702409A1 (hu) |
| FI (1) | FI79318C (hu) |
| GR (1) | GR852979B (hu) |
| HU (1) | HU194241B (hu) |
| SU (1) | SU1440348A3 (hu) |
| ZA (1) | ZA859382B (hu) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3501497A1 (de) * | 1985-01-18 | 1986-07-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| DE3531678A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3626664A1 (de) * | 1986-08-07 | 1988-02-11 | Boehringer Mannheim Gmbh | Tricyclische benzotriazole, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3639466A1 (de) * | 1986-11-18 | 1988-05-19 | Thomae Gmbh Dr K | Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE3642315A1 (de) * | 1986-12-11 | 1988-06-23 | Boehringer Mannheim Gmbh | Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3701277A1 (de) * | 1987-01-17 | 1988-07-28 | Boehringer Mannheim Gmbh | Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel |
| DE3740985A1 (de) * | 1987-12-03 | 1989-06-15 | Boehringer Mannheim Gmbh | Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation |
| DE3855327D1 (de) * | 1987-12-30 | 1996-07-04 | Orion Yhtymae Oy | Heterocyclische Verbindungen |
| US4963677A (en) * | 1987-12-30 | 1990-10-16 | Orion Corporation Ltd. | Heterocyclic lactam compounds |
| DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| DE4027592A1 (de) * | 1990-08-31 | 1992-03-05 | Beiersdorf Ag | Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
| EP1370527A1 (en) * | 2001-03-06 | 2003-12-17 | AstraZeneca AB | Indolone derivatives having vascular-damaging activity |
| EP1377549A1 (en) * | 2001-03-12 | 2004-01-07 | Millennium Pharmaceuticals, Inc. | Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor |
| CA2553968A1 (en) * | 2004-01-23 | 2005-08-11 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments of inflammatory and neuropathic pain |
| EP2895476B1 (en) | 2012-09-13 | 2016-06-22 | F.Hoffmann-La Roche Ag | 2-oxo-2,3-dihydro-indoles for the treatment of cns disorders |
| KR102633122B1 (ko) | 2014-08-01 | 2024-02-05 | 누에볼루션 에이/에스 | 브로모도메인에 대하여 활성을 갖는 화합물 |
| GB201709456D0 (en) | 2017-06-14 | 2017-07-26 | Ucb Biopharma Sprl | Therapeutic agents |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234571A (en) * | 1979-06-11 | 1980-11-18 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone |
| DE3163018D1 (en) * | 1980-02-02 | 1984-05-17 | Beecham Group Plc | Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them |
| FR2476644A1 (fr) * | 1980-02-21 | 1981-08-28 | Sarget Lab | Orthoarylydeneaminophenethylamine, leur preparation et leur utilisation therapeutique |
| DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| SU1068439A1 (ru) * | 1982-10-28 | 1984-01-23 | Новокузнецкий научно-исследовательский химико-фармацевтический институт | Производные имидазо(4,5- @ ) индолов |
| US4579865A (en) * | 1983-02-14 | 1986-04-01 | Usv Pharmaceutical Corp. | Benzofuranyl carbamates |
| US4548943A (en) * | 1984-05-11 | 1985-10-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory, analgesic, or anti-primary dysmenorrheal arylmethylene- and arylmethylindenoimidazoles |
| PL144822B1 (en) * | 1984-05-12 | 1988-07-30 | Boehringer Mannheim Gmbh | Method of obtaining novel pyrolobenzimidazoles |
| DE3501497A1 (de) * | 1985-01-18 | 1986-07-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| DE3531678A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1984
- 1984-12-14 DE DE19843445669 patent/DE3445669A1/de not_active Withdrawn
-
1985
- 1985-12-06 AT AT85115547T patent/ATE49970T1/de not_active IP Right Cessation
- 1985-12-06 DE DE8585115547T patent/DE3575725D1/de not_active Expired - Lifetime
- 1985-12-06 EP EP85115547A patent/EP0186010B1/de not_active Expired - Lifetime
- 1985-12-09 ZA ZA859382A patent/ZA859382B/xx unknown
- 1985-12-09 AU AU51006/85A patent/AU580822B2/en not_active Ceased
- 1985-12-10 US US06/807,260 patent/US4710510A/en not_active Expired - Fee Related
- 1985-12-10 ES ES549776A patent/ES8702409A1/es not_active Expired
- 1985-12-12 GR GR852979A patent/GR852979B/el unknown
- 1985-12-12 FI FI854926A patent/FI79318C/fi not_active IP Right Cessation
- 1985-12-12 CS CS859195A patent/CS276403B6/cs unknown
- 1985-12-12 DD DD85284206A patent/DD242045A5/de not_active IP Right Cessation
- 1985-12-13 SU SU853995762A patent/SU1440348A3/ru active
- 1985-12-13 DK DK579185A patent/DK579185A/da not_active Application Discontinuation
- 1985-12-13 HU HU854775A patent/HU194241B/hu not_active IP Right Cessation
- 1985-12-13 JP JP60279391A patent/JPS61158984A/ja active Granted
- 1985-12-13 CA CA000497668A patent/CA1262908A/en not_active Expired
-
1987
- 1987-10-01 US US07/103,895 patent/US4810801A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3445669A1 (de) | 1986-06-19 |
| EP0186010A1 (de) | 1986-07-02 |
| US4810801A (en) | 1989-03-07 |
| FI854926A (fi) | 1986-06-15 |
| JPS61158984A (ja) | 1986-07-18 |
| AU580822B2 (en) | 1989-02-02 |
| CS276403B6 (en) | 1992-05-13 |
| ES8702409A1 (es) | 1987-01-16 |
| GR852979B (hu) | 1986-04-08 |
| DK579185D0 (da) | 1985-12-13 |
| DE3575725D1 (de) | 1990-03-08 |
| SU1440348A3 (ru) | 1988-11-23 |
| HU194241B (en) | 1988-01-28 |
| US4710510A (en) | 1987-12-01 |
| DK579185A (da) | 1986-06-15 |
| JPH0471914B2 (hu) | 1992-11-16 |
| AU5100685A (en) | 1986-06-19 |
| ATE49970T1 (de) | 1990-02-15 |
| FI79318C (fi) | 1989-12-11 |
| FI79318B (fi) | 1989-08-31 |
| CA1262908A (en) | 1989-11-14 |
| EP0186010B1 (de) | 1990-01-31 |
| ES549776A0 (es) | 1987-01-16 |
| CS919585A3 (en) | 1992-01-15 |
| DD242045A5 (de) | 1987-01-14 |
| ZA859382B (en) | 1986-08-27 |
| FI854926A0 (fi) | 1985-12-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUT40436A (en) | Process for production pirrolo-benzimidasoles and medical preparatives containing thereof | |
| HU913193D0 (en) | 17betha-substituted 4-aza-5alpha-androstane-3-on derivatives, process for their production and for the production of medical preparations containing them | |
| PT77898A (en) | Process for the preparation of substituted 4-amino-methylenochromanes and 4-aminomethylenecromenes acting on the blood circulation and application thereof in the preparation of pharmaceutical compositions acting on the blood circulation | |
| HU903961D0 (en) | Process for producing 11-beta-aryl-4-oestrenes and pharmaceutical preparatives containing these compounds | |
| DE3260540D1 (en) | 2-aryl-3,4-diaza-bicyclo(4.n.0)alken-(2)-ones-(5), process for their preparation, and medicines containing these compounds | |
| PT76495A (en) | Process for preparing new imidazolphenyl-tetrahydropyridazines | |
| ES8607916A1 (es) | Un procedimiento para la preparacion de medicamentos influenciadores de la circulacion sanguinea, que contienen compuestos de bis (carboxamida) | |
| EP0214592A3 (en) | Pyrrolobenzimidazoles, pyrrolobenzoxazoles and pyrrolobenzothiazoles, process for their preparation and medicaments containing these products | |
| DE3371515D1 (en) | Cycloalkyl derivatives of benzisoselenazolones, process for their preparation and pharmaceutical compositions containing them | |
| DE3277971D1 (en) | Acylamino-4-aza-1-adamantanes, process for their preparation and their therapeutic use | |
| ES8802612A1 (es) | Procedimiento para preparar derivados de benzisoselenazolilo | |
| EP0207483A3 (en) | Benzimidazoles, process for their preparation, medicaments containing them and intermediates | |
| HUT44781A (en) | Process for production of 2-benzimidasolile-alkyl-tioderivatives and medical preparatives containing them as active substance | |
| HUT44515A (en) | Process for producing isoquinolinol compounds of heart activity increasing, phosphodiesterase iii inhibiting and/or renal vasodilating activity and pharmaceutical composition containing them | |
| HUT48585A (en) | Process for production of perhydrobenz /c,d/ sulphonamids and medical preparatives containing these compounds as active substance | |
| HUT45989A (en) | Process for production of derivatives of 1,4-dihydropiridine and medical preparatives containing them as active substance | |
| JPS5753475A (en) | Novel thiazolyl-2-oxamic acid derivative, manufacture and medicine containing same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |