HUP9904592A2 - 1,2-Ditiolán-származékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyászati készítmények - Google Patents

1,2-Ditiolán-származékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyászati készítmények

Info

Publication number
HUP9904592A2
HUP9904592A2 HU9904592A HUP9904592A HUP9904592A2 HU P9904592 A2 HUP9904592 A2 HU P9904592A2 HU 9904592 A HU9904592 A HU 9904592A HU P9904592 A HUP9904592 A HU P9904592A HU P9904592 A2 HUP9904592 A2 HU P9904592A2
Authority
HU
Hungary
Prior art keywords
compounds
dithiolane
derivatives
production
group
Prior art date
Application number
HU9904592A
Other languages
English (en)
Inventor
Yves Charton
Solo Goldstein
Claude Guillonneau
Pierre Lestage
Brian Lockhart
Original Assignee
Adir Et Compagnie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir Et Compagnie filed Critical Adir Et Compagnie
Publication of HU9904592D0 publication Critical patent/HU9904592D0/hu
Publication of HUP9904592A2 publication Critical patent/HUP9904592A2/hu
Publication of HUP9904592A3 publication Critical patent/HUP9904592A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A találmány tárgyát (I) általános képletű vegyületek képezik, ahol Ra jelentése lineáris vagy elágazó láncú C1-C8 alkiléncsoport, a Rb jelentése egyszeres kötés vagy lineáris vagy elágazó láncú C1-C6alkiléncsoport, Z jelentése tiokarbamát vagy tioamidcsoport, amelyek adott esetbenhelyettesítettek, T jelentése adott esetben helyettesített morfolinocsoport. A találmánytárgyához tartoznak a vegyületek izomerjei és gyógyászati szempontbólelfogadható savakkal vagy bázisokkal képzett addíciós sói. A találmányszerinti vegyületek antioxidáns hatásúak. Ó
HU9904592A 1998-12-15 1999-12-15 1,2-dithiolane-derivatives, process for their production and medicaments containing them HUP9904592A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9815821A FR2787109B1 (fr) 1998-12-15 1998-12-15 Nouveaux derives de 1,2-dithiolane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
HU9904592D0 HU9904592D0 (en) 2000-02-28
HUP9904592A2 true HUP9904592A2 (hu) 2001-04-28
HUP9904592A3 HUP9904592A3 (en) 2001-09-28

Family

ID=9533988

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9904592A HUP9904592A3 (en) 1998-12-15 1999-12-15 1,2-dithiolane-derivatives, process for their production and medicaments containing them

Country Status (22)

Country Link
US (1) US6150358A (hu)
EP (1) EP1010698B1 (hu)
JP (1) JP3256787B2 (hu)
KR (1) KR20000057059A (hu)
CN (1) CN1131226C (hu)
AT (1) ATE215080T1 (hu)
AU (1) AU756213B2 (hu)
BR (1) BR9908661A (hu)
CA (1) CA2292248C (hu)
DE (1) DE69901088D1 (hu)
DK (1) DK1010698T3 (hu)
EA (1) EA003424B1 (hu)
ES (1) ES2174582T3 (hu)
FR (1) FR2787109B1 (hu)
HK (1) HK1027348A1 (hu)
HU (1) HUP9904592A3 (hu)
NO (1) NO996179L (hu)
NZ (1) NZ501783A (hu)
PL (1) PL337172A1 (hu)
PT (1) PT1010698E (hu)
SI (1) SI1010698T1 (hu)
ZA (1) ZA997707B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413707B1 (en) 2000-12-29 2002-07-02 Eastman Kodak Company Photographic element with yellow dye-forming coupler and stabilizing compound having improved light stability
US7202270B2 (en) * 2003-06-20 2007-04-10 Sami Labs Limited Convenient stable non-hygroscopic crystalline solid forms of racemic and chiral LA-plus salts: process for their manufacture and uses
JP2010520333A (ja) * 2007-03-01 2010-06-10 セダーズ−シナイ メディカル センター 〔１，２〕−ジチオラン部分を含有する抗酸化剤重合体およびその使用
US9028874B2 (en) * 2008-01-03 2015-05-12 Cedars-Sinai Medical Center Antioxidant nanosphere comprising [1,2]-dithiolane moieties
US8603531B2 (en) * 2008-06-02 2013-12-10 Cedars-Sinai Medical Center Nanometer-sized prodrugs of NSAIDs
ES2529060T3 (es) 2008-11-24 2015-02-16 Cedars-Sinai Medical Center Derivados antioxidantes de la camptotecina y nanoesferas antineoplásicas antioxidantes de los mismos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU586174A1 (ru) * 1976-04-26 1977-12-30 Уфимский Нефтяной Институт Способ получени 1,3-дитиациклоалканов
US4178291A (en) * 1976-12-03 1979-12-11 E. R. Squibb & Sons, Inc. Substituted acyl derivatives of amino acids
CH656382A5 (de) * 1983-10-24 1986-06-30 Sandoz Ag Sulfoxide, verfahren zu ihrer herstellung und ihre verwendung.
FR2707983A1 (fr) * 1993-07-21 1995-01-27 Pf Medicament Nouveaux dérivés de l'acide lipoïque et dihydrolipoïque, leur préparation et leur application en thérapeutique humaine.
IL123887A0 (en) * 1997-04-02 1998-10-30 Sankyo Co Dithiolan derivatives their use and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
SI1010698T1 (en) 2002-06-30
BR9908661A (pt) 2000-10-17
DK1010698T3 (da) 2002-07-22
CA2292248C (fr) 2004-04-13
KR20000057059A (ko) 2000-09-15
PL337172A1 (en) 2000-06-19
NZ501783A (en) 2000-09-29
FR2787109B1 (fr) 2001-01-19
CN1257072A (zh) 2000-06-21
PT1010698E (pt) 2002-07-31
US6150358A (en) 2000-11-21
EA199901034A3 (ru) 2000-10-30
HK1027348A1 (en) 2001-01-12
JP3256787B2 (ja) 2002-02-12
AU6523899A (en) 2000-06-22
EA199901034A1 (ru) 2000-10-30
DE69901088D1 (de) 2002-05-02
NO996179L (no) 2000-06-16
FR2787109A1 (fr) 2000-06-16
CN1131226C (zh) 2003-12-17
JP2000178270A (ja) 2000-06-27
HU9904592D0 (en) 2000-02-28
EP1010698A1 (fr) 2000-06-21
HUP9904592A3 (en) 2001-09-28
ATE215080T1 (de) 2002-04-15
ES2174582T3 (es) 2002-11-01
EA003424B1 (ru) 2003-04-24
AU756213B2 (en) 2003-01-09
NO996179D0 (no) 1999-12-14
CA2292248A1 (fr) 2000-06-15
ZA997707B (en) 2000-06-27
EP1010698B1 (fr) 2002-03-27

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