HUP9904438A2 - Eljárás a {2-[4-(alfa-fenil-p-klór-benzil)-piperazin-1-il]-etoxi}-ecetsav előállítására - Google Patents
Eljárás a {2-[4-(alfa-fenil-p-klór-benzil)-piperazin-1-il]-etoxi}-ecetsav előállításáraInfo
- Publication number
- HUP9904438A2 HUP9904438A2 HU9904438A HUP9904438A HUP9904438A2 HU P9904438 A2 HUP9904438 A2 HU P9904438A2 HU 9904438 A HU9904438 A HU 9904438A HU P9904438 A HUP9904438 A HU P9904438A HU P9904438 A2 HUP9904438 A2 HU P9904438A2
- Authority
- HU
- Hungary
- Prior art keywords
- phenyl
- ethoxy
- chloro
- benzyl
- alpha
- Prior art date
Links
- ZKLPARSLTMPFCP-UHFFFAOYSA-N Cetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 abstract 7
- 239000002253 acid Substances 0.000 abstract 5
- LVJDQBJDVOYDLA-UHFFFAOYSA-N 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetamide Chemical compound C1CN(CCOCC(=O)N)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 LVJDQBJDVOYDLA-UHFFFAOYSA-N 0.000 abstract 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 239000002184 metal Chemical class 0.000 abstract 2
- 239000003444 phase transfer catalyst Substances 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9904438A HU226641B1 (en) | 1999-11-30 | 1999-11-30 | Process for producing {2-[4-(alpha-phenyl-p-chloro-benzyl)-piperazine-1-yl]-ethoxy}-acetic acid |
| AT00981508T ATE280165T1 (de) | 1999-11-30 | 2000-11-29 | Verfahren zur herstellung von 2-(4-(alpha-phenyl- p-chlorobenzyl)piperazin-1-yl)ethoxyessigsäure und zwischenprodukte dafür |
| PCT/HU2000/000123 WO2001040211A1 (en) | 1999-11-30 | 2000-11-29 | A PROCESS FOR THE PREPARATION OF {2-[4-(α-PHENYL-p-CHLOROBENZYL)PIPERAZIN-1-YL]ETHOXY}ACETIC ACID AND NOVEL INTERMEDIATES THEREFOR |
| US10/148,704 US6908999B2 (en) | 1999-11-30 | 2000-11-29 | Process for the preparation of {2-[4-α-phenyl-p-chlorobenzyl)piperazin-1-yl]ethoxy} acetic acid and novel intermediates therefor |
| RU2002118101/04A RU2248974C2 (ru) | 1999-11-30 | 2000-11-29 | Способ получения {2-[4-(альфа-фенил-п-хлорбензил)пиперазин-1-ил]-этокси}-уксусной кислоты и новые промежуточные соединения |
| EP00981508A EP1233954B1 (en) | 1999-11-30 | 2000-11-29 | A process for the preparation of 2- 4-(alpha-phenyl-p-chlorobenzyl)piperazin-1-yl]ethoxy acetic acid and novel intermediates therefor |
| DE60015177T DE60015177T2 (de) | 1999-11-30 | 2000-11-29 | Verfahren zur herstellung von 2-[4-(alpha-phenyl-p-chlorobenzyl)piperazin-1-yl]ethoxyessigsäure und zwischenprodukte dafür |
| CZ2002-1712A CZ304892B6 (cs) | 1999-11-30 | 2000-11-29 | Způsob přípravy {2-[4-(α-fenyl-p-chlorbenzyl)piperazin-1-yl]ethoxy}octové kyseliny a nové meziprodukty |
| SI200030569T SI1233954T1 (en) | 1999-11-30 | 2000-11-29 | A process for the preparation of 2- 4-(alpha-phenyl-p-chlorobenzyl)piperazin-1-yl)ethoxy acetic acid and novel intermediates therefor |
| JP2001541895A JP4763954B2 (ja) | 1999-11-30 | 2000-11-29 | ｛２−［４−（α−フェニル−ｐ−クロロベンジル）ピペラジン−１−イル］エトキシ｝酢酸の製法及びそのための新規な中間体 |
| SK752-2002A SK285641B6 (sk) | 1999-11-30 | 2000-11-29 | Spôsob prípravy {2-[4-(alfa-fenyl-p-chlórbenzyl)piperazin-1- yl]etoxy}octovej kyseliny a nové medziprodukty |
| UA2002065341A UA72949C2 (uk) | 1999-11-30 | 2000-11-29 | СПОСІБ ОДЕРЖАННЯ {2-[4-(α-ФЕНІЛ-П-ХЛОРБЕНЗИЛ)ПІПЕРАЗИН-1-ІЛ]-ЕТОКСІ}ОЦТОВОЇ КИСЛОТИ І ПРОМІЖНІ СПОЛУКИ |
| PL354677A PL200046B1 (pl) | 1999-11-30 | 2000-11-29 | Proces otrzymywania kwasu {2-[4-(α-fenylo-p-chlorobenzylo)piperazyno-1-ilo] etoksy}octowego, związki pośrednie oraz proces ich otrzymywania |
| AU18742/01A AU1874201A (en) | 1999-11-30 | 2000-11-29 | A process for the preparation of (2-(4-(alpha-phenyl-p-chlorobenzyl)piperazin-1-yl)ethoxy) acetic acid and novel intermediates therefor |
| HR20020470A HRP20020470B1 (en) | 1999-11-30 | 2002-05-28 | A PROCESS FOR THE PREPARATION OF {2-[4-(alpha-PHENYL-p-CHLORBENZYL)-PIPERAZIN-1-YL]ETHOXY} ACETIC ACID AND NOVEL INTERMEDIATES THEREFOR |
| BG106760A BG65455B1 (bg) | 1999-11-30 | 2002-05-30 | МЕТОД ЗА ПОЛУЧАВАНЕ НА {2-[4-(алфа-ФЕНИЛ-р-ХЛОРОБЕНЗИЛ) ПИПЕРАЗИН-1-ИЛ]ЕТОКСИ}ОЦЕТНА КИСЕЛИНА И НОВИ МЕЖДИННИ СЪЕДИНЕНИЯ |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9904438A HU226641B1 (en) | 1999-11-30 | 1999-11-30 | Process for producing {2-[4-(alpha-phenyl-p-chloro-benzyl)-piperazine-1-yl]-ethoxy}-acetic acid |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| HU9904438D0 HU9904438D0 (en) | 2000-01-28 |
| HUP9904438A2 true HUP9904438A2 (hu) | 2001-12-28 |
| HUP9904438A3 HUP9904438A3 (en) | 2002-01-28 |
| HU226641B1 HU226641B1 (en) | 2009-05-28 |
Family
ID=90000074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9904438A HU226641B1 (en) | 1999-11-30 | 1999-11-30 | Process for producing {2-[4-(alpha-phenyl-p-chloro-benzyl)-piperazine-1-yl]-ethoxy}-acetic acid |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HU226641B1 (hu) |
-
1999
- 1999-11-30 HU HU9904438A patent/HU226641B1/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9904438A3 (en) | 2002-01-28 |
| HU9904438D0 (en) | 2000-01-28 |
| HU226641B1 (en) | 2009-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC9A | Change of name, address |
Owner name: EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDOE RESZV, HU Free format text: FORMER OWNER(S): EGIS GYOGYSZERGYAR RT., HU |
|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |