HUP9903732A2 - cGMP-szintjét növelő szerek alkalmazása a jóindulatú prosztatatúltengés kezelésére szolgáló gyógyszerkészítmények előállítására - Google Patents
cGMP-szintjét növelő szerek alkalmazása a jóindulatú prosztatatúltengés kezelésére szolgáló gyógyszerkészítmények előállításáraInfo
- Publication number
- HUP9903732A2 HUP9903732A2 HU9903732A HUP9903732A HUP9903732A2 HU P9903732 A2 HUP9903732 A2 HU P9903732A2 HU 9903732 A HU9903732 A HU 9903732A HU P9903732 A HUP9903732 A HU P9903732A HU P9903732 A2 HUP9903732 A2 HU P9903732A2
- Authority
- HU
- Hungary
- Prior art keywords
- benign prostatic
- prostatic hyperplasia
- preparation
- pharmaceutical compositions
- treating benign
- Prior art date
Links
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 title abstract 2
- 208000004403 Prostatic Hyperplasia Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 2
- 206010020853 Hypertonic bladder Diseases 0.000 abstract 1
- 206010071289 Lower urinary tract symptoms Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 239000000695 adrenergic alpha-agonist Substances 0.000 abstract 1
- 208000006111 contracture Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 abstract 1
- 235000013928 guanylic acid Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány tárgya eljárás a jóindűlatú prősztatatúltengés, azinstabil hólyag-összehúzódásők és az alsó húgyúti tünetek kezelésére,amely abban áll, hőgy egy ilyen kezelésre szőrűló betegnek valamely, aciklikűs gűanőzin-mőnőfőszfát-szintjét növelő hatóanyagnak, ahatóanyag sójának, szőlvátjának vagy ezek bármelyikét tartalmazógyógyászati készítménynek a hatás kifejtéséhez szükséges mennyiségétadagőlják, adőtt esetben egy a-adrenergantagőnista hatóanyaggalegyütt, mégpedig vagy űgyanabban a gyógyászati készítményben, vagykülön-külön. ŕ
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10509798P | 1998-10-21 | 1998-10-21 |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9903732D0 HU9903732D0 (en) | 1999-12-28 |
HUP9903732A2 true HUP9903732A2 (hu) | 2000-08-28 |
HUP9903732A3 HUP9903732A3 (en) | 2002-01-28 |
Family
ID=22304008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9903732A HUP9903732A3 (en) | 1998-10-21 | 1999-10-20 | Use of cgmp elevators for the preparation of pharmaceutical compositions treating benign prostatic hyperplasia |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1020190A3 (hu) |
JP (1) | JP2000128804A (hu) |
KR (1) | KR20000029222A (hu) |
AR (1) | AR020850A1 (hu) |
AU (1) | AU5597799A (hu) |
CA (1) | CA2287122A1 (hu) |
CO (1) | CO5150210A1 (hu) |
HU (1) | HUP9903732A3 (hu) |
IL (1) | IL132406A0 (hu) |
PE (1) | PE20001282A1 (hu) |
ZA (1) | ZA996622B (hu) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW536402B (en) | 1998-06-26 | 2003-06-11 | Yamanouchi Pharma Co Ltd | Pharmaceutical composition for the therapy of voiding dysfunction |
BRPI0014526C1 (pt) | 1999-09-16 | 2021-05-25 | Mitsubishi Tanabe Pharma Corp | compostos cíclicos de seis elementos contendo nitrogênio aromático, composição farmacêutica e uso do mesmo |
TWI265925B (en) | 1999-10-11 | 2006-11-11 | Pfizer | Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them |
MXPA02010693A (es) | 2000-04-28 | 2003-03-10 | Tanabe Seiyaku Co | Compuestos ciclicos. |
US7273868B2 (en) | 2000-04-28 | 2007-09-25 | Tanabe Seiyaku Co., Ltd. | Pyrazine derivatives |
IT1318674B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Faramaci per l'incontinenza. |
JP2001288115A (ja) * | 2001-02-07 | 2001-10-16 | Yamanouchi Pharmaceut Co Ltd | 下部尿路症治療剤 |
WO2002062389A1 (fr) * | 2001-02-08 | 2002-08-15 | Ono Pharmaceutical Co., Ltd. | Remedes pour des maladies urinaires contenant des agents de regulation du recepteur de lpa |
NZ527741A (en) | 2001-02-26 | 2005-02-25 | Tanabe Seiyaku Co | Pyridopyrimidine or naphthyridine derivative |
DE10135815A1 (de) | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
BRPI0616633A2 (pt) * | 2005-09-29 | 2011-06-28 | Bayer Healthcare Ag | inibidores de pde e combinações dos mesmos para o tratamento de transtornos urológicos |
US20070093493A1 (en) * | 2005-10-12 | 2007-04-26 | Lilly Icos Llc | Treatment of benign prostatic hypertrophy and lower urinary tract symptoms |
AR058119A1 (es) * | 2005-12-20 | 2008-01-23 | Pfizer Prod Inc | Combinacion farmaceutica para el tratamiento de sintomas del tracto urinario inferior (stui) |
RU2010115647A (ru) * | 2007-10-02 | 2011-11-10 | Донг-А Фарм.Ко., Лтд. (Kr) | Композиция и способ лечения или профилактики доброкачественной гиперплазии предстательной железы и симптомов со стороны нижних отделов мочевыводящих путей |
KR20110062943A (ko) * | 2009-12-04 | 2011-06-10 | 주식회사종근당 | 퀴나졸린 유도체를 유효성분으로 하는 전립선 비대증 예방 또는 치료제 |
EP2875824B1 (en) | 2012-05-11 | 2018-01-03 | KAEL-GemVax Co.,Ltd | Composition for preventing or treating cachexia |
WO2013167299A1 (en) | 2012-05-11 | 2013-11-14 | Kael-Gemvax Co., Ltd. | Anti-inflammatory peptides and composition comprising the same |
US10967000B2 (en) | 2012-07-11 | 2021-04-06 | Gemvax & Kael Co., Ltd. | Cell-penetrating peptide, conjugate comprising same and composition comprising same |
US9907838B2 (en) | 2013-04-19 | 2018-03-06 | Gemvax & Kael Co., Ltd. | Composition and methods for treating ischemic damage |
RU2677277C2 (ru) | 2013-06-07 | 2019-01-16 | Джемвакс Энд Каэл Ко., Лтд. | Биологические маркеры, которые могут быть использованы в иммунотерапии рака |
KR20160039152A (ko) | 2013-06-21 | 2016-04-08 | 주식회사 젬백스앤카엘 | 호르몬 분비 조절제, 이를 포함하는 조성물, 및 이를 사용한 호르몬 분비 조절 방법 |
ES2773296T3 (es) | 2013-10-23 | 2020-07-10 | Gemvax & Kael Co Ltd | Composición para tratar y prevenir la hiperplasia prostática benigna |
US10034922B2 (en) | 2013-11-22 | 2018-07-31 | Gemvax & Kael Co., Ltd. | Peptide having angiogenesis inhibitory activity and composition containing same |
JP6367950B2 (ja) | 2013-12-17 | 2018-08-01 | ジェムバックス アンド カエル カンパニー,リミティド | 前立腺癌治療用組成物 |
WO2015156649A1 (ko) | 2014-04-11 | 2015-10-15 | 주식회사 젬백스앤카엘 | 섬유증 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
US10662223B2 (en) | 2014-04-30 | 2020-05-26 | Gemvax & Kael Co., Ltd. | Composition for organ, tissue, or cell transplantation, kit, and transplantation method |
KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
CN107405380B (zh) | 2015-02-27 | 2021-04-20 | 珍白斯凯尔有限公司 | 用于预防听觉损伤的肽及其包含该肽的组合物 |
KR102638286B1 (ko) | 2015-07-02 | 2024-02-20 | 주식회사 젬백스앤카엘 | 항바이러스 활성 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
KR20180123512A (ko) | 2016-04-07 | 2018-11-16 | 주식회사 젬백스앤카엘 | 텔로머라제 활성 증가 및 텔로미어 연장 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9114760D0 (en) * | 1991-07-09 | 1991-08-28 | Pfizer Ltd | Therapeutic agents |
GB9401090D0 (en) * | 1994-01-21 | 1994-03-16 | Glaxo Lab Sa | Chemical compounds |
DE19540642A1 (de) * | 1995-11-01 | 1997-05-07 | Stief Christian Georg Priv Doz | Verwendung von Inhibitoren der Phosphodiesterase bei der Behandlung von Prostataerkrankungen |
DE19642322A1 (de) * | 1996-10-14 | 1998-04-16 | Bayer Ag | Neue 3-Heterocyclyl-substituierte Pyrazolderivate |
DE19709126A1 (de) * | 1997-03-06 | 1998-09-10 | Bayer Ag | Arylamin-, -oxy-, -thio-substituierte Dihydropurinone und Pyrazolopyrimidine |
AU3621097A (en) * | 1997-07-09 | 1999-02-08 | Wolf-Georg Forssmann | Use of phosphordiesterase inhibitors in the treatment of prostatic diseases |
-
1999
- 1999-10-14 IL IL13240699A patent/IL132406A0/xx unknown
- 1999-10-15 EP EP99308148A patent/EP1020190A3/en not_active Withdrawn
- 1999-10-19 PE PE1999001053A patent/PE20001282A1/es not_active Application Discontinuation
- 1999-10-19 CA CA002287122A patent/CA2287122A1/en not_active Abandoned
- 1999-10-20 JP JP11297837A patent/JP2000128804A/ja active Pending
- 1999-10-20 ZA ZA9906622A patent/ZA996622B/xx unknown
- 1999-10-20 AR ARP990105301A patent/AR020850A1/es not_active Application Discontinuation
- 1999-10-20 AU AU55977/99A patent/AU5597799A/en not_active Abandoned
- 1999-10-20 HU HU9903732A patent/HUP9903732A3/hu unknown
- 1999-10-21 CO CO99066723A patent/CO5150210A1/es unknown
- 1999-10-21 KR KR1019990045737A patent/KR20000029222A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU5597799A (en) | 2000-05-04 |
HUP9903732A3 (en) | 2002-01-28 |
JP2000128804A (ja) | 2000-05-09 |
EP1020190A3 (en) | 2000-10-25 |
EP1020190A2 (en) | 2000-07-19 |
AR020850A1 (es) | 2002-05-29 |
CO5150210A1 (es) | 2002-04-29 |
CA2287122A1 (en) | 2000-04-21 |
IL132406A0 (en) | 2001-03-19 |
HU9903732D0 (en) | 1999-12-28 |
ZA996622B (en) | 2001-04-20 |
KR20000029222A (ko) | 2000-05-25 |
PE20001282A1 (es) | 2000-11-18 |
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