HUP9901433A3 - Hydrophobic taxane derivatives and medicaments comprising them - Google Patents

Hydrophobic taxane derivatives and medicaments comprising them

Info

Publication number
HUP9901433A3
HUP9901433A3 HU9901433A HUP9901433A HUP9901433A3 HU P9901433 A3 HUP9901433 A3 HU P9901433A3 HU 9901433 A HU9901433 A HU 9901433A HU P9901433 A HUP9901433 A HU P9901433A HU P9901433 A3 HUP9901433 A3 HU P9901433A3
Authority
HU
Hungary
Prior art keywords
medicaments
taxane derivatives
hydrophobic taxane
hydrophobic
derivatives
Prior art date
Application number
HU9901433A
Other languages
English (en)
Original Assignee
Liposome Company Inc Princeton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Company Inc Princeton filed Critical Liposome Company Inc Princeton
Publication of HUP9901433A2 publication Critical patent/HUP9901433A2/hu
Publication of HUP9901433A3 publication Critical patent/HUP9901433A3/hu
Publication of HU226325B1 publication Critical patent/HU226325B1/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
HU9901433A 1995-09-12 1996-09-12 Hydrolysis-promoting hydrophobic taxane derivatives, medicaments comprising them and the use of medicaments HU226325B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US357595P 1995-09-12 1995-09-12
PCT/US1996/014631 WO1997010234A1 (en) 1995-09-12 1996-09-12 Hydrolysis-promoting taxane hydrophobic derivatives

Publications (3)

Publication Number Publication Date
HUP9901433A2 HUP9901433A2 (hu) 2001-04-28
HUP9901433A3 true HUP9901433A3 (en) 2001-05-28
HU226325B1 HU226325B1 (en) 2008-08-28

Family

ID=21706522

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901433A HU226325B1 (en) 1995-09-12 1996-09-12 Hydrolysis-promoting hydrophobic taxane derivatives, medicaments comprising them and the use of medicaments

Country Status (22)

Country Link
US (1) US5703117A (hu)
EP (1) EP0902783B1 (hu)
JP (1) JP4192208B2 (hu)
KR (1) KR100401220B1 (hu)
CN (1) CN1100770C (hu)
AT (2) ATE309235T1 (hu)
CA (1) CA2231750C (hu)
CZ (1) CZ288562B6 (hu)
DE (2) DE69635428T2 (hu)
DK (2) DK0902783T3 (hu)
ES (2) ES2179208T3 (hu)
HK (1) HK1016169A1 (hu)
HU (1) HU226325B1 (hu)
IL (1) IL123595A (hu)
MX (1) MX9801871A (hu)
NO (1) NO319521B1 (hu)
NZ (1) NZ318300A (hu)
PL (1) PL187738B1 (hu)
PT (1) PT902783E (hu)
SK (1) SK283199B6 (hu)
TR (1) TR199800443T1 (hu)
WO (1) WO1997010234A1 (hu)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107332A (en) * 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6667053B1 (en) * 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
TR200002243T2 (tr) * 1997-11-10 2000-12-21 Memorial Sloan-Kettering Cancer Center Arsenik trioksitin hazırlanması için işlem ve bunların kanser tedavisi için kullanımı.
BR9911031A (pt) * 1998-05-20 2002-01-29 Liposome Co Inc Novas formulações em partìculas
US6146659A (en) * 1998-07-01 2000-11-14 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
DE60004630T2 (de) * 1999-01-12 2004-06-17 Quanam Medical Corp., Santa Clara Arzneimittel und verfahren zur verabreichung von wasserunlöslichen paclitaxelderivaten
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
CA2410632A1 (en) 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
US6607689B1 (en) * 2000-08-29 2003-08-19 Micron Technology, Inc. Layer thickness control for stereolithography utilizing variable liquid elevation and laser focal length
EP1304103B1 (en) * 2001-10-22 2008-12-31 Viroblock SA New non-phospholipid lipid vesicles (npLV) and their use in cosmetic, therapeutic and prophylactic applications
AU2002351169B2 (en) * 2001-11-26 2007-09-20 Intas Pharmaceuticals Limited Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions
WO2004002455A1 (en) * 2002-06-26 2004-01-08 Medigene Oncology Gmbh Novel method of stabilizing diagnostic and therapeutic compounds in a cationic carrier system
WO2004069224A2 (en) 2003-02-03 2004-08-19 Neopharm, Inc. Stable sterile filterable liposomal encapsulated taxane and other antineoplastic drugs
CN105879114A (zh) * 2005-02-18 2016-08-24 阿布拉西斯生物科学公司 用于整合入医疗装置的疏水性改善的药物
WO2006110862A2 (en) * 2005-04-12 2006-10-19 Wisconsin Alumni Research Foundation Micelle composition of polymer and passenger drug
MX2010011165A (es) * 2008-04-10 2011-02-22 Abraxis Bioscience Llc Composiciones de derivados de taxano hidrofobos y sus usos.
TW200942233A (en) * 2008-04-10 2009-10-16 Abraxis Bioscience Llc Compositions of hydrophobic taxane derivatives and uses thereof
EP2480207B1 (en) 2009-09-25 2016-11-09 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
CN105503844A (zh) * 2015-12-11 2016-04-20 上海大学 C-13和c-7位结构改造的紫杉醇类化合物及其制备方法
CN111004195B (zh) * 2019-12-03 2022-01-28 沈阳药科大学 卡巴他赛弱碱性衍生物及其制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
HU225294B1 (en) * 1992-12-23 2006-09-28 Bristol Myers Squibb Co Oxazoline derivatives for synthesis of sidechain-bearing taxanes and preparation thereof
IL108316A (en) * 1993-01-15 2006-10-31 Univ Florida State History of C-10 Texan and pharmaceuticals containing them
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives

Also Published As

Publication number Publication date
DK1229030T3 (da) 2006-02-13
HU226325B1 (en) 2008-08-28
ATE216377T1 (de) 2002-05-15
HUP9901433A2 (hu) 2001-04-28
NO981071D0 (no) 1998-03-11
DK0902783T3 (da) 2002-07-22
CA2231750C (en) 2006-07-11
NZ318300A (en) 1999-08-30
HK1016169A1 (en) 1999-10-29
DE69620802T2 (de) 2002-10-10
JP4192208B2 (ja) 2008-12-10
WO1997010234A1 (en) 1997-03-20
DE69620802D1 (de) 2002-05-23
ATE309235T1 (de) 2005-11-15
AU6975696A (en) 1997-04-01
DE69635428T2 (de) 2006-06-14
CN1202166A (zh) 1998-12-16
SK283199B6 (sk) 2003-03-04
CN1100770C (zh) 2003-02-05
SK33498A3 (en) 1998-08-05
TR199800443T1 (xx) 1998-06-22
ES2252347T3 (es) 2006-05-16
KR19990044409A (ko) 1999-06-25
CZ288562B6 (cs) 2001-07-11
MX9801871A (es) 1998-05-31
KR100401220B1 (ko) 2004-03-20
CZ71198A3 (cs) 1998-07-15
IL123595A0 (en) 1998-10-30
AU706290B2 (en) 1999-06-10
PL325477A1 (en) 1998-07-20
EP0902783A1 (en) 1999-03-24
DE69635428D1 (de) 2005-12-15
PL187738B1 (pl) 2004-09-30
NO981071L (no) 1998-05-12
ES2179208T3 (es) 2003-01-16
EP0902783B1 (en) 2002-04-17
NO319521B1 (no) 2005-08-22
EP0902783A4 (hu) 1999-03-24
US5703117A (en) 1997-12-30
IL123595A (en) 2000-10-31
PT902783E (pt) 2002-09-30
CA2231750A1 (en) 1997-03-20
JP2001519755A (ja) 2001-10-23

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: CEPHALON LIMITED, GB

Free format text: FORMER OWNER(S): THE LIPOSOME COMPANY, INC., US