HUP9901039A2 - Neisseria meningitidis B-csoportba tartozó külső-membrán-fehérjéjének (MB3) expressziója élesztőben, továbbá vakcinák - Google Patents
Neisseria meningitidis B-csoportba tartozó külső-membrán-fehérjéjének (MB3) expressziója élesztőben, továbbá vakcinákInfo
- Publication number
- HUP9901039A2 HUP9901039A2 HU9901039A HUP9901039A HUP9901039A2 HU P9901039 A2 HUP9901039 A2 HU P9901039A2 HU 9901039 A HU9901039 A HU 9901039A HU P9901039 A HUP9901039 A HU P9901039A HU P9901039 A2 HUP9901039 A2 HU P9901039A2
- Authority
- HU
- Hungary
- Prior art keywords
- pipe
- expression
- yeast
- outer membrane
- belonging
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 3
- 241000588650 Neisseria meningitidis Species 0.000 title abstract 2
- 239000012528 membrane Substances 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 210000002418 meninge Anatomy 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 230000005924 vaccine-induced immune response Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1097296P | 1996-02-01 | 1996-02-01 | |
| US2044096P | 1996-06-13 | 1996-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP9901039A2 true HUP9901039A2 (hu) | 1999-07-28 |
Family
ID=26681820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9901039A HUP9901039A2 (hu) | 1996-02-01 | 1997-01-31 | Neisseria meningitidis B-csoportba tartozó külső-membrán-fehérjéjének (MB3) expressziója élesztőben, továbbá vakcinák |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0877816A1 (no) |
| JP (1) | JP2001508758A (no) |
| KR (1) | KR19990082265A (no) |
| AU (1) | AU2115897A (no) |
| HU (1) | HUP9901039A2 (no) |
| IL (1) | IL125420A0 (no) |
| NO (1) | NO983474L (no) |
| PL (1) | PL328096A1 (no) |
| WO (1) | WO1997028273A1 (no) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL338146A1 (en) | 1997-07-17 | 2000-09-25 | North American Vaccine | Immunogenic complex combinations consisting of meningococcal porine of b group and h. influenzae polysaccharide |
| MX339406B (es) | 1998-05-01 | 2016-05-25 | Novartis Vaccines & Diagnostic | Antigenos de neisseria meningitidis y composiciones que los contienen. |
| DE69941406D1 (de) * | 1998-07-06 | 2009-10-22 | Tosoh Corp | IL-6 Rezeptor IL-6-gekoppeltes Fusionsprotein |
| JP4524816B2 (ja) * | 1998-07-06 | 2010-08-18 | 東ソー株式会社 | Ｉｌ−６レセプター・ｉｌ−６直結融合蛋白質 |
| GB9818004D0 (en) * | 1998-08-18 | 1998-10-14 | Smithkline Beecham Biolog | Novel compounds |
| EP1228217B1 (en) | 1999-04-30 | 2012-11-21 | Novartis Vaccines and Diagnostics S.r.l. | Conserved neisserial antigens |
| MXPA01011499A (es) | 1999-05-13 | 2002-06-04 | American Cyanamid Co | Formulaciones de combinacion de adyuvantes. |
| CN102580072A (zh) * | 1999-05-19 | 2012-07-18 | 诺华疫苗和诊断有限公司 | 组合式奈瑟球菌组合物 |
| EP1069133A1 (en) * | 1999-07-13 | 2001-01-17 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Neisseria meningitidis compounds and anti-infection applications thereof |
| GB9928196D0 (en) * | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| CN1433471A (zh) * | 1999-11-29 | 2003-07-30 | 启龙股份公司 | 85kgDa奈瑟球菌的抗原 |
| DK1248647T3 (da) | 2000-01-17 | 2010-09-27 | Novartis Vaccines & Diagnostic | Ydre membranvesikel (OMV) vaccine omfattende N. meningitidis serogruppe B ydre membranproteiner |
| JP4846160B2 (ja) | 2000-02-28 | 2011-12-28 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | ナイセリア属のタンパク質のハイブリッド発現 |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| ES2775098T3 (es) | 2002-10-11 | 2020-07-23 | Glaxosmithkline Biologicals Sa | Vacunas de polipéptidos para protección amplia contra linajes meningocócicos hipervirulentos |
| ES2411080T3 (es) | 2003-01-30 | 2013-07-04 | Novartis Ag | Vacunas inyectables contra múltiples serogrupos de meningococos |
| JP2006262846A (ja) * | 2005-03-25 | 2006-10-05 | Niigata Bio Research Park Kk | 酵母による２−デオキシ−シロ−イノソースの合成および精製する方法並びに得られた２−デオキシ−シロ−イノソース |
| KR100919704B1 (ko) * | 2007-09-12 | 2009-10-06 | 한국생명공학연구원 | 효모에서 재조합단백질을 고효율로 분비발현시키는 방법 |
| JP2011116658A (ja) * | 2008-03-13 | 2011-06-16 | Chemo-Sero-Therapeutic Research Inst | 豚萎縮性鼻炎用薬剤の製造方法 |
| WO2015073801A1 (en) | 2013-11-14 | 2015-05-21 | Duke University | Tetanus toxoid and ccl3 improve dc vaccines |
| CN106146679B (zh) * | 2015-04-23 | 2019-02-01 | 中国医学科学院医学生物学研究所 | 一种纯化细菌荚膜多糖的方法 |
| PL3294762T3 (pl) | 2015-05-11 | 2022-04-25 | Impossible Foods Inc. | Konstrukty ekspresyjne i sposoby inżynierii genetycznej drożdży metylotroficznych |
| BR112018013376A2 (pt) * | 2015-12-30 | 2018-12-18 | Dsm Ip Assets Bv | hidrólise enzimática parcial de triacilgliceróis |
| KR20210153106A (ko) | 2019-04-17 | 2021-12-16 | 임파서블 푸즈 인크. | 단백질 생산을 위한 물질 및 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356170A (en) * | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| NZ239643A (en) * | 1990-09-17 | 1996-05-28 | North American Vaccine Inc | Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group. |
| US5268273A (en) * | 1990-12-14 | 1993-12-07 | Phillips Petroleum Company | Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same |
| US5439808A (en) * | 1993-07-23 | 1995-08-08 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis |
-
1997
- 1997-01-31 WO PCT/US1997/001687 patent/WO1997028273A1/en not_active Application Discontinuation
- 1997-01-31 PL PL97328096A patent/PL328096A1/xx unknown
- 1997-01-31 EP EP97906470A patent/EP0877816A1/en not_active Ceased
- 1997-01-31 JP JP52788197A patent/JP2001508758A/ja active Pending
- 1997-01-31 KR KR1019980705994A patent/KR19990082265A/ko not_active Application Discontinuation
- 1997-01-31 HU HU9901039A patent/HUP9901039A2/hu unknown
- 1997-01-31 IL IL12542097A patent/IL125420A0/xx unknown
- 1997-01-31 AU AU21158/97A patent/AU2115897A/en not_active Abandoned
-
1998
- 1998-07-28 NO NO983474A patent/NO983474L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR19990082265A (ko) | 1999-11-25 |
| AU2115897A (en) | 1997-08-22 |
| NO983474L (no) | 1998-09-30 |
| EP0877816A1 (en) | 1998-11-18 |
| WO1997028273A1 (en) | 1997-08-07 |
| NO983474D0 (no) | 1998-07-28 |
| JP2001508758A (ja) | 2001-07-03 |
| IL125420A0 (en) | 1999-03-12 |
| PL328096A1 (en) | 1999-01-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP9901039A2 (hu) | Neisseria meningitidis B-csoportba tartozó külső-membrán-fehérjéjének (MB3) expressziója élesztőben, továbbá vakcinák | |
| AU657487B2 (en) | Nucleotide sequence coding for an outer membrane protein from neisseria meningitidis and use of said protein in vaccine preparations | |
| WO1990006696A3 (en) | Meningococcal class 1 outer-membrane protein vaccine | |
| EP1006782A4 (en) | POLYPEPTIDES FUSIONED WITH ALFALFAMOSAIC VIRALS OR ILARVIRAL CAPSIDES | |
| DK1002110T3 (da) | Immunsvar mod HPV-antigener fremkaldt af sammensætninger, som omfatter et HPV-antigen og et stressprotein eller en ekspressionsvektor i stand til at ekspressere disse proteiner | |
| NO913518L (no) | Vaksiner for ikke typebestembar haemophilus influenzae. | |
| ATE229978T1 (de) | Helicobacter proteine und impstoffe | |
| DE3472114D1 (en) | Plasmids and modified strains of vibrio cholerae, their preparation and derived vaccines | |
| NO20000774D0 (no) | Mutanter og gram-negative mukøse bakterier, og anvendelse derav i vaksiner | |
| AU7481498A (en) | Immuno-reactive peptide ctl epitopes of human cytomegalovirus | |
| NO912825D0 (no) | Fremgangsmaate for fremstilling av cokonjugate vaksiner omfattende immunogenisk protein, hiv-beslektede peptider og anioniske grupper. | |
| CA2014033A1 (en) | Compositions and treatments for pneumonia in animals | |
| EA200300640A1 (ru) | Фармацевтические композиции, усиливающие иммуногенность антигенов со слабой иммуногенностью | |
| DK1267924T3 (da) | Immunterapeutiske metoder og sammensætninger | |
| DE69728289D1 (de) | Immunoreaktive peptid ctl epitope von menschlichem cytomegalovirus | |
| FI924457A0 (fi) | Kompositioner och behandlingsfoerfarande foer lunginflammation i djur | |
| EP1105157A4 (en) | PROTEIN ADMINISTRATION SYSTEM USING PARTICLES LIKE THE HUMAN PAPILLOMAVIRUS. | |
| DE60130634D1 (de) | Identifizierung von antigenen peptiden durch zytotoxische t-lymphozyten aktiviert von dendritischen zellhybriden | |
| DK0952771T3 (da) | Hidtil ukendte saponinpræparater og anvendelser deraf | |
| CA2133108A1 (en) | Pasteurella haemolytica type a-1 bacterin-toxoid vaccine | |
| Alkadah et al. | Different profile and distribution of antigen specific T cells induced by intranasal and intrarectal immunization with rotavirus 2/6-VLP with and without LT-R192G | |
| MY126769A (en) | Dna sequence encoding the specific and antigenic outer membrane protein of salmonella typhi | |
| Czerkinsky et al. | Lymphoid cell populations dynamics and the mucosal immune response in humans | |
| ES2017258A6 (es) | Un metodo para producir peptidos antigenicos relacionados con el antigeno p97 asociado a melanoma. | |
| CA2007248A1 (en) | Meningococcal class 1 outer-membrane protein vaccine |