IL125420A0 - Expression of group b neisseria meningitidis outer membrane (mb3) protein from yeast and vaccines containing said protein - Google Patents

Expression of group b neisseria meningitidis outer membrane (mb3) protein from yeast and vaccines containing said protein

Info

Publication number
IL125420A0
IL125420A0 IL12542097A IL12542097A IL125420A0 IL 125420 A0 IL125420 A0 IL 125420A0 IL 12542097 A IL12542097 A IL 12542097A IL 12542097 A IL12542097 A IL 12542097A IL 125420 A0 IL125420 A0 IL 125420A0
Authority
IL
Israel
Prior art keywords
protein
yeast
expression
group
outer membrane
Prior art date
Application number
IL12542097A
Original Assignee
North American Vaccine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by North American Vaccine Inc filed Critical North American Vaccine Inc
Publication of IL125420A0 publication Critical patent/IL125420A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
IL12542097A 1996-02-01 1997-01-31 Expression of group b neisseria meningitidis outer membrane (mb3) protein from yeast and vaccines containing said protein IL125420A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1097296P 1996-02-01 1996-02-01
US2044096P 1996-06-13 1996-06-13
PCT/US1997/001687 WO1997028273A1 (en) 1996-02-01 1997-01-31 Expression of group b neisseria meningitidis outer membrane (mb3) protein from yeast and vaccines

Publications (1)

Publication Number Publication Date
IL125420A0 true IL125420A0 (en) 1999-03-12

Family

ID=26681820

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12542097A IL125420A0 (en) 1996-02-01 1997-01-31 Expression of group b neisseria meningitidis outer membrane (mb3) protein from yeast and vaccines containing said protein

Country Status (9)

Country Link
EP (1) EP0877816A1 (en)
JP (1) JP2001508758A (en)
KR (1) KR19990082265A (en)
AU (1) AU2115897A (en)
HU (1) HUP9901039A2 (en)
IL (1) IL125420A0 (en)
NO (1) NO983474L (en)
PL (1) PL328096A1 (en)
WO (1) WO1997028273A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010021953A (en) 1997-07-17 2001-03-15 추후제출 Immunogenic conjugates comprising a group b meningococcal porin and an h. influenzae polysaccharide
ES2294629T3 (en) 1998-05-01 2008-04-01 Novartis Vaccines And Diagnostics, Inc. ANTIGENS OF NEISSERIA AND COMPOSITIONS.
JP4524816B2 (en) * 1998-07-06 2010-08-18 東ソー株式会社 IL-6 receptor / IL-6 direct fusion protein
WO2000001731A1 (en) * 1998-07-06 2000-01-13 Tosoh Corporation Fused protein with direct bond of il-6-receptor to il-6
GB9818004D0 (en) * 1998-08-18 1998-10-14 Smithkline Beecham Biolog Novel compounds
ES2397918T3 (en) 1999-04-30 2013-03-12 Novartis Vaccines And Diagnostics S.R.L. Neisserial antigens conserved
HUP0201220A3 (en) 1999-05-13 2004-07-28 Wyeth Holdings Corp Madison Adjuvant combination formulations
EP1860191A3 (en) * 1999-05-19 2008-02-13 Novartis Vaccines and Diagnostics S.r.l. Combination neisserial compositions
EP1069133A1 (en) * 1999-07-13 2001-01-17 Institut National De La Sante Et De La Recherche Medicale (Inserm) Neisseria meningitidis compounds and anti-infection applications thereof
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
AU1875301A (en) 1999-11-29 2001-06-04 Chiron S.P.A. 85kda neisserial antigen
PT2289545T (en) 2000-01-17 2016-09-06 Glaxosmithkline Biologicals Sa Supplemented omv vaccine against meningococcus
ATE352631T1 (en) 2000-02-28 2007-02-15 Novartis Vaccines & Diagnostic HETEROLOGUE EXPRESSION OF NEISSERIA PROTEINS
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
SI2353608T1 (en) 2002-10-11 2020-12-31 Glaxosmithkline Biologicals Sa Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
US10272147B2 (en) 2003-01-30 2019-04-30 Glaxosmithkline Biologicals S.A. Injectable vaccines against multiple meningococcal serogroups
JP2006262846A (en) * 2005-03-25 2006-10-05 Niigata Bio Research Park Kk Method for synthesizing and purifying 2-deoxy-scyllo-inosose with yeast and obtained 2-deoxy-scyllo-inosose
KR100919704B1 (en) * 2007-09-12 2009-10-06 한국생명공학연구원 An Effective Method for Expressing and Secreting Recombinant Proteins in Yeast
JP2011116658A (en) * 2008-03-13 2011-06-16 Chemo-Sero-Therapeutic Research Inst Manufacturing method of medicine for swine atrophic rhinitis
WO2015073801A1 (en) 2013-11-14 2015-05-21 Duke University Tetanus toxoid and ccl3 improve dc vaccines
CN106146679B (en) * 2015-04-23 2019-02-01 中国医学科学院医学生物学研究所 A kind of method of purification of bacterial capsular polysaccharide
EP3397759A2 (en) * 2015-12-30 2018-11-07 DSM IP Assets B.V. Partial enzymatic hydrolysis of triacylglycerols
SG11202111468SA (en) * 2019-04-17 2021-11-29 Impossible Foods Inc Materials and methods for protein production

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
NZ239643A (en) * 1990-09-17 1996-05-28 North American Vaccine Inc Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group.
US5268273A (en) * 1990-12-14 1993-12-07 Phillips Petroleum Company Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis

Also Published As

Publication number Publication date
HUP9901039A2 (en) 1999-07-28
AU2115897A (en) 1997-08-22
EP0877816A1 (en) 1998-11-18
NO983474L (en) 1998-09-30
JP2001508758A (en) 2001-07-03
KR19990082265A (en) 1999-11-25
WO1997028273A1 (en) 1997-08-07
NO983474D0 (en) 1998-07-28
PL328096A1 (en) 1999-01-04

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