HUP9900993A3 - Nitric oxide donors capable of reducing toxicity from drugs - Google Patents

Nitric oxide donors capable of reducing toxicity from drugs

Info

Publication number
HUP9900993A3
HUP9900993A3 HU9900993A HUP9900993A HUP9900993A3 HU P9900993 A3 HUP9900993 A3 HU P9900993A3 HU 9900993 A HU9900993 A HU 9900993A HU P9900993 A HUP9900993 A HU P9900993A HU P9900993 A3 HUP9900993 A3 HU P9900993A3
Authority
HU
Hungary
Prior art keywords
drugs
nitric oxide
oxide donors
reducing toxicity
donors capable
Prior art date
Application number
HU9900993A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11373387&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9900993(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of HUP9900993A2 publication Critical patent/HUP9900993A2/hu
Publication of HUP9900993A3 publication Critical patent/HUP9900993A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Underground Structures, Protecting, Testing And Restoring Foundations (AREA)
HU9900993A 1996-02-26 1997-02-24 Nitric oxide donors capable of reducing toxicity from drugs HUP9900993A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI000352A IT1282686B1 (it) 1996-02-26 1996-02-26 Composti in grado di ridurre la tossicita' da farmaci

Publications (2)

Publication Number Publication Date
HUP9900993A2 HUP9900993A2 (hu) 1999-09-28
HUP9900993A3 true HUP9900993A3 (en) 2000-10-30

Family

ID=11373387

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900993A HUP9900993A3 (en) 1996-02-26 1997-02-24 Nitric oxide donors capable of reducing toxicity from drugs

Country Status (16)

Country Link
US (1) US7087588B2 (cg-RX-API-DMAC10.html)
EP (2) EP1221326A3 (cg-RX-API-DMAC10.html)
JP (1) JP2000506133A (cg-RX-API-DMAC10.html)
KR (1) KR19990087113A (cg-RX-API-DMAC10.html)
AT (1) ATE220920T1 (cg-RX-API-DMAC10.html)
AU (1) AU706591B2 (cg-RX-API-DMAC10.html)
BR (1) BR9707739A (cg-RX-API-DMAC10.html)
CA (1) CA2247848C (cg-RX-API-DMAC10.html)
DE (1) DE69714253T2 (cg-RX-API-DMAC10.html)
DK (1) DK0904110T3 (cg-RX-API-DMAC10.html)
ES (1) ES2180938T3 (cg-RX-API-DMAC10.html)
HU (1) HUP9900993A3 (cg-RX-API-DMAC10.html)
IT (1) IT1282686B1 (cg-RX-API-DMAC10.html)
PT (1) PT904110E (cg-RX-API-DMAC10.html)
RU (1) RU2192247C2 (cg-RX-API-DMAC10.html)
WO (1) WO1997031654A1 (cg-RX-API-DMAC10.html)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US6043232A (en) * 1997-07-23 2000-03-28 Nitromed, Inc. Nitroso esters of beta-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs
GB9801398D0 (en) 1998-01-22 1998-03-18 Anggard Erik E Chemical compounds
IT1298338B1 (it) * 1998-03-05 1999-12-20 Nicox Sa Composizioni farmaceutiche per l'ulcera
JP2002528495A (ja) 1998-10-30 2002-09-03 ニトロメド インコーポレーテッド ニトロソ化およびニトロシル化された非ステロイド抗炎症性化合物、組成物および使用方法
TWI243672B (en) 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs
TWI262791B (en) 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
US6552078B2 (en) 1999-10-27 2003-04-22 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
EP1246621A4 (en) 1999-12-23 2004-11-24 Nitromed Inc NITROSED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS FOR THEIR USE
WO2001054680A2 (en) * 2000-01-26 2001-08-02 Cedars-Sinai Medical Center Method for using potassium channel activation for delivering a medicant to an abnormal brain region and/or a malignant tumor
US7018979B1 (en) 2000-01-26 2006-03-28 Cedars-Sinai Medical Center Method for using potassium channel agonists for delivering a medicant to an abnormal brain region and/or a malignant tumor
EP1406609B1 (en) 2000-12-21 2006-09-06 Nitromed, Inc. Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
EP1219306A1 (en) * 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
US7211561B2 (en) 2001-10-12 2007-05-01 Cedars-Sinai Medical Center Method for inducing selective cell death of malignant cells by activation of calcium-activated potassium channels (KCa)
WO2003088961A1 (en) 2002-04-19 2003-10-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disorders
JP2006501161A (ja) 2002-06-11 2006-01-12 ニトロメッド インク． ニトロソ化および／またはニトロシル化シクロオキシゲナーゼ−２選択的阻害剤、組成物ならびに使用方法
JP2005535642A (ja) 2002-06-28 2005-11-24 ニトロメッド インコーポレーティッド オキシムおよび／またはヒドラゾンを含有するニトロソ化および／またはニトロシル化シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法
JP2005539089A (ja) 2002-07-03 2005-12-22 ニトロメッド インコーポレーティッド ニトロソ化非ステロイド性抗炎症化合物、組成物および使用方法
WO2004010945A2 (en) 2002-07-29 2004-02-05 Nitromed, Inc. Cyclooxygenase- 2 selective inhibitors, compositions and methods of use
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
CN1914149A (zh) * 2004-01-27 2007-02-14 默克弗罗斯特公司 用于治疗处于血栓形成心血管事件危险中的患者的环氧合酶－2为媒的疾病或状况的组合治疗
KR20070045187A (ko) * 2004-06-10 2007-05-02 고쿠리츠다이가쿠호진 도호쿠다이가쿠 항암제의 효과 증강제
JP2007325501A (ja) * 2004-08-25 2007-12-20 Tottori Univ 非ステロイド性抗炎症薬による動物の消化管副作用の予防・治療方法
WO2006128121A2 (en) 2005-05-27 2006-11-30 The University Of North Carolina At Chapel Hill Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
US20100240745A1 (en) * 2009-03-20 2010-09-23 Nicox S.A. Method of treatment of inflammation in hypertensive patients
EP4249001A3 (en) 2009-08-21 2023-11-29 Novan, Inc. Topical gels
DK2467173T3 (da) 2009-08-21 2019-07-29 Novan Inc Sårbandager, fremgangsmåder til anvendelse heraf og fremgangsmåder til dannelse deraf
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
WO2012118819A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same
JO3350B1 (ar) 2011-03-07 2019-03-13 Merck Sharp & Dohme مشتقات حلقية غير متجانسة محتوية على مجموعات أمينو أولية ومركبات داي أزينيومديولات
RU2539630C1 (ru) * 2013-07-09 2015-01-20 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Способ профилактики ишемии сетчатки в эксперименте

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5570683A (en) 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
IT1256345B (it) 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
CA2173582C (en) 1993-10-06 2006-11-28 Piero Del Soldato Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
DE69512232T2 (de) 1994-05-10 2000-02-24 Nicox S.A., Paris Nitroverbindingen und ihre zubereitungen mit entzündungsremmenden, schmertzlindernden und antithrombotischen wirkungen
US5597809A (en) * 1994-06-23 1997-01-28 Massachusetts Eye & Ear Infirmary Treatment of optic neuritis
US5703073A (en) 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US5620416A (en) 1995-06-07 1997-04-15 North Carolina State University Methods of using topical agents with systemically administered active agents

Also Published As

Publication number Publication date
DE69714253D1 (de) 2002-08-29
KR19990087113A (ko) 1999-12-15
ITMI960352A1 (it) 1997-08-26
EP0904110A1 (en) 1999-03-31
ATE220920T1 (de) 2002-08-15
US7087588B2 (en) 2006-08-08
IT1282686B1 (it) 1998-03-31
RU2192247C2 (ru) 2002-11-10
DK0904110T3 (da) 2002-11-11
EP0904110B1 (en) 2002-07-24
DE69714253T2 (de) 2003-03-06
US20040242651A1 (en) 2004-12-02
EP1221326A2 (en) 2002-07-10
ITMI960352A0 (cg-RX-API-DMAC10.html) 1996-02-26
CA2247848C (en) 2008-07-15
AU2092497A (en) 1997-09-16
AU706591B2 (en) 1999-06-17
ES2180938T3 (es) 2003-02-16
CA2247848A1 (en) 1997-09-04
HUP9900993A2 (hu) 1999-09-28
JP2000506133A (ja) 2000-05-23
BR9707739A (pt) 1999-07-27
PT904110E (pt) 2002-12-31
EP1221326A3 (en) 2004-01-14
WO1997031654A1 (en) 1997-09-04

Similar Documents

Publication Publication Date Title
HUP9900993A3 (en) Nitric oxide donors capable of reducing toxicity from drugs
IL105806A0 (en) Aminoquinoline derivatives and pharmaceutical compositions containing the same
IL106431A0 (en) Aminediol derivatives and pharmaceutical compositions containing the same
CZ99396A3 (en) Macrolide compounds and pharmaceutical composition containing thereof
IL105218A0 (en) Hexanones and pharmaceutical compositions containing them
IL105223A0 (en) Cyclohexane-ylidenes and pharmaceutical compositions containing them
HU9602188D0 (en) Novel carbamate derivative and medicinal composition containing the same
ZA94345B (en) C7 Taxane derivatives and pharmaceutical compositions containing them
IL111221A0 (en) N-alkyl-n- arylpyrimidinamine derivatives and pharmaceutical compositions containing them
HUP9904149A3 (en) Nitrate esters of corticoid compounds and pharmaceutical applications thereof
IL114622A0 (en) Heteroaryl-oxazolidinones and pharmaceutical compositions containing them
HUP0000474A3 (en) Arylethenesulfonamide derivatives and drug composition containing the same
AU2137497A (en) Taxoid anti-tumor agents and pharmaceutical compositions thereof
AU3460297A (en) Taxane derivatives and drugs containing the same
HUP9904335A3 (en) Arylpiperidinol and arylpiperidine derivatives and drugs containing the same
HUP0004398A3 (en) Alpha-aryl-n-alkylnitrones and pharmaceutical compositions containing the same
IL110988A0 (en) 4-arylamino-benzopyran derivatives and pharmaceutical compositions containing the same
IL133097A0 (en) Aroyl-piperazine derivatives pharmaceutical compositions containing the same and the use thereof
GB2271059B (en) Pharmaceutical compositions comprising aconitane derivatives and tetrahydroprotoberberine derivatives.
IL107449A0 (en) Compositions and methods for reducing toxicity and increasing the efficacy of drugs
HUP9901452A3 (en) Bicyclic-aromatic compounds and pharmaceutical compositions containing them
IL106098A0 (en) Heteroarylnaphthalenes and pharmaceutical compositions containing them
IL104623A0 (en) Biphenyl-substituted quinoline derivatives and pharmaceutical compositions containing the same
IL130093A0 (en) Hexanitrohexaazaisowurtzitane compositions and explosive compositions containing the same
HUT65713A (en) Thienyl-pyrrolidinyl-carbapenem-derivatives providing antibiotic effect and pharmaceutical compositions containing it

Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: NICOX S.A., FR

Free format text: FORMER OWNER(S): NICOX S.A., FR

FD9A Lapse of provisional protection due to non-payment of fees