HUP9802705A3 - Aromatic compounds process for producing them and pharmaceutical compositions containing them - Google Patents
Aromatic compounds process for producing them and pharmaceutical compositions containing themInfo
- Publication number
- HUP9802705A3 HUP9802705A3 HU9802705A HUP9802705A HUP9802705A3 HU P9802705 A3 HUP9802705 A3 HU P9802705A3 HU 9802705 A HU9802705 A HU 9802705A HU P9802705 A HUP9802705 A HU P9802705A HU P9802705 A3 HUP9802705 A3 HU P9802705A3
- Authority
- HU
- Hungary
- Prior art keywords
- producing
- pharmaceutical compositions
- compositions containing
- aromatic compounds
- compounds process
- Prior art date
Links
- 150000001491 aromatic compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/18—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9512475.6A GB9512475D0 (en) | 1995-06-20 | 1995-06-20 | Aromatic compounds |
GBGB9601465.9A GB9601465D0 (en) | 1996-01-25 | 1996-01-25 | Aromatic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9802705A2 HUP9802705A2 (hu) | 1999-02-01 |
HUP9802705A3 true HUP9802705A3 (en) | 1999-03-29 |
Family
ID=26307242
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9802705A HUP9802705A3 (en) | 1995-06-20 | 1996-06-17 | Aromatic compounds process for producing them and pharmaceutical compositions containing them |
Country Status (29)
Country | Link |
---|---|
US (2) | US6100258A (hu) |
EP (1) | EP0847391B1 (hu) |
JP (1) | JP3949167B2 (hu) |
KR (1) | KR19990023007A (hu) |
CN (1) | CN1114598C (hu) |
AR (1) | AR004670A1 (hu) |
AT (1) | ATE211132T1 (hu) |
AU (1) | AU699691B2 (hu) |
BG (1) | BG63778B1 (hu) |
BR (1) | BR9608908A (hu) |
CA (1) | CA2220529A1 (hu) |
CZ (1) | CZ290924B6 (hu) |
DE (1) | DE69618210T2 (hu) |
DK (1) | DK0847391T3 (hu) |
EE (1) | EE9700342A (hu) |
ES (1) | ES2169248T3 (hu) |
HR (1) | HRP960289B1 (hu) |
HU (1) | HUP9802705A3 (hu) |
IL (1) | IL118663A (hu) |
MX (1) | MX9710261A (hu) |
MY (1) | MY132432A (hu) |
NO (1) | NO311131B1 (hu) |
NZ (1) | NZ311083A (hu) |
PL (1) | PL324166A1 (hu) |
PT (1) | PT847391E (hu) |
RU (1) | RU2198878C2 (hu) |
SK (1) | SK282458B6 (hu) |
TW (1) | TW502026B (hu) |
WO (1) | WO1997000864A1 (hu) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9514160D0 (en) * | 1994-07-25 | 1995-09-13 | Zeneca Ltd | Aromatic compounds |
GB9417532D0 (en) * | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
TW434240B (en) * | 1995-06-20 | 2001-05-16 | Zeneca Ltd | Aromatic compounds, preparation thereof and pharmaceutical composition comprising same |
TW502026B (en) * | 1995-06-20 | 2002-09-11 | Zeneca Ltd | Aromatic compounds useful as antagonists of e-type prostaglandins, processes for the preparation thereof, pharmaceutical compositions comprising the compounds, and intermediates |
EP0752421B1 (en) | 1995-07-07 | 2005-10-12 | AstraZeneca AB | Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists |
US5981195A (en) * | 1995-07-26 | 1999-11-09 | Nps Pharmaceuticals, Inc. | Chimeric receptors and methods for identifying compounds active at metabotropic glutamate receptors |
DE69826286T2 (de) * | 1997-06-27 | 2005-11-24 | Fujisawa Pharmaceutical Co., Ltd. | Derivate mit einem aromatischen ring |
GB9903476D0 (en) * | 1999-02-17 | 1999-04-07 | Zeneca Ltd | Therapeutic agents |
AU6589801A (en) * | 2000-04-28 | 2001-11-12 | F. Hoffmann-La Roche Ag | P-(sulfonyl)aryl and heteroaryls |
SE0100873D0 (sv) * | 2001-03-13 | 2001-03-13 | Astrazeneca Ab | Method of treatment |
ATE391503T1 (de) | 2001-10-23 | 2008-04-15 | Serono Lab | Pyrazolidinon-verbindungen als liganden des ep2 und/oder ep4 prostaglandin-rezeptoren |
JP4554931B2 (ja) | 2001-12-20 | 2010-09-29 | メルク セローノ ソシエテ アノニム | プロスタグランジン調節物質としてのピロリジン誘導体 |
JP4754820B2 (ja) | 2002-06-10 | 2011-08-24 | メルク セローノ ソシエテ アノニム | プロスタグランジン作動薬としてのγラクタムおよびその使用 |
EP1534679A4 (en) * | 2002-08-30 | 2007-06-06 | Biostratum Inc | INHIBITORS OF POST-AMADORI ADVANCED GLYCATION ENDPRODUCTS |
DE602005019090D1 (de) | 2004-12-06 | 2010-03-11 | Merck Serono Sa Coinsins | Pyrrolidin-2-on-Derivate zur Verwendung als DP1-Rezeptoragonisten |
AU2005318372A1 (en) | 2004-12-23 | 2006-06-29 | Glaxo Group Limited | Pyridine compounds for the treatment of prostaglandin mediated diseases |
US20060269579A1 (en) * | 2005-05-25 | 2006-11-30 | Musculoskeletal Research Llc | Compositions for treating osteoarthritis |
US7767710B2 (en) | 2005-05-25 | 2010-08-03 | Calosyn Pharma, Inc. | Method for treating osteoarthritis |
BRPI0807942A2 (pt) | 2007-02-16 | 2014-07-01 | Ono Pharmaceutical Co | Agente terapêutico para distúrbio de excreção urinária |
US20090163440A1 (en) * | 2007-09-26 | 2009-06-25 | Waddell David D | Ion-Channel Regulator Compositions and Methods of Using Same |
AR081331A1 (es) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos |
AR081626A1 (es) | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos |
WO2011133920A1 (en) | 2010-04-23 | 2011-10-27 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
US20120101282A1 (en) | 2010-10-22 | 2012-04-26 | Pascal Dott | Process for the preparation of nicotinamide derivatives |
US8759380B2 (en) | 2011-04-22 | 2014-06-24 | Cytokinetics, Inc. | Certain heterocycles, compositions thereof, and methods for their use |
RS58594B1 (sr) * | 2013-12-17 | 2019-05-31 | Lilly Co Eli | Jedinjenja dimetilbenzoeve kiseline |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3632760A (en) * | 1969-06-25 | 1972-01-04 | Merck & Co Inc | Treatment of inflammation |
US3657430A (en) * | 1969-06-25 | 1972-04-18 | Merck & Co Inc | Composition and methods for treating inflammation |
DE2120091A1 (de) * | 1971-04-24 | 1972-11-09 | Agfa-Gevaert Ag, 5090 Leverkusen | Farbbildner für das Peroxid-Farbverstärkungs-Verfahren |
US4350822A (en) * | 1975-03-12 | 1982-09-21 | American Cyanamid Company | Antilipidemicpara-[aryl(alkyl or alkenyl)amino]benzoic acid derivatives |
AU510758B2 (en) * | 1976-01-19 | 1980-07-10 | The Dow Chemical Company | P-benzylaminobenzoic acids |
GB1576007A (en) * | 1976-02-11 | 1980-10-01 | Beecham Group Ltd | Hypolipidaemic compositions |
US4206145A (en) * | 1976-02-11 | 1980-06-03 | Beecham Group Limited | Hypolipidaemic compounds and compositions |
EP0000816A1 (en) * | 1977-08-06 | 1979-02-21 | Beecham Group Plc | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them |
US4152452A (en) * | 1977-10-06 | 1979-05-01 | William H. Rorer, Inc. | Method of topically treating inflammation |
GB2041363B (en) * | 1979-01-19 | 1982-10-06 | Pfizer Ltd | N-benzyl-imidazoles |
US4277496A (en) * | 1979-06-04 | 1981-07-07 | Laboratorios Bago S.A. | Methods of treating mammals suffering from inflammation and pain |
US4578390A (en) * | 1981-12-14 | 1986-03-25 | Merck & Co., Inc. | Hydroxybenzylamino derivatives as anti-inflammatory agents |
CA1193598A (en) * | 1982-05-06 | 1985-09-17 | Rafael Foguet | 2-amino-benzoic acid derivatives and processes for their production |
US5105017A (en) * | 1983-07-18 | 1992-04-14 | Eli Lilly And Company | Leukotriene antagonist intermediates |
GB8320699D0 (en) * | 1983-08-01 | 1983-09-01 | Wellcome Found | Ethylenediamines |
US4614617A (en) * | 1985-02-25 | 1986-09-30 | G. D. Searle & Co. | Intermediates for 8-chlorodibenz[(b,f)][1,4]oxazepine-10(11H)-carboxylic acid, 2-(sulfinyl- and sulfonyl-containing acyl)hydrazides |
US4631287A (en) * | 1985-04-16 | 1986-12-23 | Usv Pharmaceutical Corp. | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4728668A (en) * | 1985-04-16 | 1988-03-01 | Usv Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4725619A (en) * | 1985-04-16 | 1988-02-16 | Usv Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4704386A (en) * | 1985-08-29 | 1987-11-03 | G. D. Searle & Co. | 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(phenylsulfinyl-, and phenylsulfonyl)alkanoyl]hydrazides |
US4937373A (en) * | 1988-12-08 | 1990-06-26 | Hoffmann-La Roche Inc. | Substituted naphthalene carboxylic acids |
DE3903989A1 (de) * | 1989-02-10 | 1990-09-20 | Basf Ag | Diphenylheteroalkylderivate, ihre herstellung und daraus hergestellte arzneimittel und kosmetika |
IL99246A0 (en) * | 1990-09-10 | 1992-07-15 | Abbott Lab | Angiotensin ii receptor antagonists and pharmaceutical compositions containing them |
US5250548A (en) * | 1990-09-10 | 1993-10-05 | Abbott Laboratories | Angiotensin II receptor antagonists |
US5284954A (en) * | 1990-09-10 | 1994-02-08 | Abbott Laboratories | Process for the preparation of tetrazoles |
US5210206A (en) * | 1990-09-10 | 1993-05-11 | Abbott Laboratories | 1,3-oxazolyl substituted biphenyl |
GB9021813D0 (en) * | 1990-10-08 | 1990-11-21 | Ici Plc | Tricyclic heterocycles |
SG64322A1 (en) * | 1991-05-10 | 1999-04-27 | Rhone Poulenc Rorer Int | Bis mono and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase |
US5480883A (en) * | 1991-05-10 | 1996-01-02 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
GB9120640D0 (en) * | 1991-09-27 | 1991-11-06 | Ici Plc | Tricyclic heterocycles |
US5324743A (en) * | 1992-12-10 | 1994-06-28 | Eli Lilly And Company | Leukotriene B4 antagonists |
DE4241632A1 (de) * | 1992-12-10 | 1994-06-16 | Thomae Gmbh Dr K | Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
US5420270A (en) * | 1993-10-07 | 1995-05-30 | G. D. Searle & Co. | Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5441950A (en) * | 1994-06-09 | 1995-08-15 | G. D. Searle & Co. | Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use |
GB9514160D0 (en) * | 1994-07-25 | 1995-09-13 | Zeneca Ltd | Aromatic compounds |
GB9417532D0 (en) * | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
GB9420557D0 (en) * | 1994-10-12 | 1994-11-30 | Zeneca Ltd | Aromatic compounds |
US5530157A (en) * | 1995-02-16 | 1996-06-25 | Scios Nova Inc. | Anti-inflammatory benzoic acid derivatives |
TW502026B (en) * | 1995-06-20 | 2002-09-11 | Zeneca Ltd | Aromatic compounds useful as antagonists of e-type prostaglandins, processes for the preparation thereof, pharmaceutical compositions comprising the compounds, and intermediates |
TW434240B (en) * | 1995-06-20 | 2001-05-16 | Zeneca Ltd | Aromatic compounds, preparation thereof and pharmaceutical composition comprising same |
EP0752421B1 (en) * | 1995-07-07 | 2005-10-12 | AstraZeneca AB | Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists |
-
1996
- 1996-06-12 TW TW085107057A patent/TW502026B/zh not_active IP Right Cessation
- 1996-06-16 IL IL11866396A patent/IL118663A/en not_active IP Right Cessation
- 1996-06-17 US US08/973,915 patent/US6100258A/en not_active Expired - Fee Related
- 1996-06-17 EE EE9700342A patent/EE9700342A/xx unknown
- 1996-06-17 KR KR1019970709477A patent/KR19990023007A/ko active IP Right Grant
- 1996-06-17 CZ CZ19974110A patent/CZ290924B6/cs not_active IP Right Cessation
- 1996-06-17 DK DK96920937T patent/DK0847391T3/da active
- 1996-06-17 MX MX9710261A patent/MX9710261A/es unknown
- 1996-06-17 AU AU62321/96A patent/AU699691B2/en not_active Ceased
- 1996-06-17 BR BR9608908A patent/BR9608908A/pt not_active Application Discontinuation
- 1996-06-17 CA CA002220529A patent/CA2220529A1/en not_active Abandoned
- 1996-06-17 JP JP50365497A patent/JP3949167B2/ja not_active Expired - Fee Related
- 1996-06-17 PT PT96920937T patent/PT847391E/pt unknown
- 1996-06-17 PL PL96324166A patent/PL324166A1/xx unknown
- 1996-06-17 CN CN96196394A patent/CN1114598C/zh not_active Expired - Fee Related
- 1996-06-17 HU HU9802705A patent/HUP9802705A3/hu unknown
- 1996-06-17 DE DE69618210T patent/DE69618210T2/de not_active Expired - Fee Related
- 1996-06-17 AT AT96920937T patent/ATE211132T1/de not_active IP Right Cessation
- 1996-06-17 RU RU98100866/04A patent/RU2198878C2/ru not_active IP Right Cessation
- 1996-06-17 NZ NZ311083A patent/NZ311083A/xx unknown
- 1996-06-17 EP EP96920937A patent/EP0847391B1/en not_active Expired - Lifetime
- 1996-06-17 ES ES96920937T patent/ES2169248T3/es not_active Expired - Lifetime
- 1996-06-17 WO PCT/GB1996/001443 patent/WO1997000864A1/en not_active Application Discontinuation
- 1996-06-17 SK SK1733-97A patent/SK282458B6/sk unknown
- 1996-06-18 HR HR960289A patent/HRP960289B1/xx not_active IP Right Cessation
- 1996-06-19 MY MYPI96002482A patent/MY132432A/en unknown
- 1996-06-20 AR ARP960103225A patent/AR004670A1/es not_active Application Discontinuation
-
1997
- 1997-12-19 NO NO19975984A patent/NO311131B1/no unknown
-
1998
- 1998-01-09 BG BG102174A patent/BG63778B1/bg unknown
-
2000
- 2000-04-03 US US09/541,306 patent/US6313148B1/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP9802705A3 (en) | Aromatic compounds process for producing them and pharmaceutical compositions containing them | |
HUP9900055A3 (en) | 4-aryl-1-phenylalkyl-1,2,3,6-tetrahydropyridin -derivatives, process for producing them and pharmaceutical compositions containing them | |
HU9603484D0 (en) | Pharmaceutical compositions and process for producing symptom-transduction | |
HUP9601529A3 (en) | Pyrimidinedion-, pyrimidinetrion-, triazinedion-, tetrahydro-quinazolinedion- derivatives, pharmaceutical compositions containing them, process for producing them and their use | |
HUP9602511A3 (en) | Aryl-diazinone derivatives, pharmaceutical compositions containing them, and process for producing all these | |
HUP9603433A3 (en) | 4-6-diaryl-pyrimidine-derivatives, process for producing them and pharmaceutical compositions containing them | |
HUP0004334A3 (en) | Substituted 1,2,3,4-tetrahydronaphthalene derivatives, process for producing them and pharmaceutical compositions containing them | |
HUP9603023A3 (en) | Substituted (sulfonimidamido)benzoyl-guanidine derivatives, process for producing them and pharmaceutical compositions containing them | |
HUP9602681A1 (en) | Hydroxy-pyridinone derivatives, process for producing them and pharmaceutical compositions containing them | |
HUP9601034A3 (en) | Aryl-alkyl-pyridazinone compounds, process for producing them, and pharmaceutical compositions containing them | |
HU9602640D0 (en) | Substituted benzoyl-guanidine derivatives, process for producing them and pharmaceutical compositions containing them | |
HUP9602748A3 (en) | Novel n-pyrimidinyl-sulfonamides, process for producing them and pharmaceutical compositions containing them | |
HUP0003823A2 (en) | Cyanoguanidines process for producing them and pharmaceutical compositions containing them | |
HU9400934D0 (en) | Thiadiazinone derivatives, pharmaceutical compositions containing them and process for producing them | |
HUP9900105A3 (en) | Momopiperazine derivatives, process for producing them and pharmaceutical compositions containing them | |
ZA966154B (en) | Aminophenylphosphonic acid compounds process for preparing them and pharmaceutical compositions containing them | |
ZA963350B (en) | Cycloheaxane compounds process for their preparation and pharmaceutical compositions containing them | |
HU9503932D0 (en) | Substituted benzol-sulfonyl-ureas and-thioureas, pharmaceutical compositions containing them and process for producing them | |
HUT76129A (en) | Arthropocidal compounds, compositions containing them and process for their preparation | |
HUP9601331A3 (en) | Piperazine- and homopiperazine-derivatives, process for producing them and pharmaceutical compositions containing them | |
HUT73982A (en) | Substituted benzol-sulfonyl-ureas and -thioureas, process for producing them, pharmaceutical compositions containing them, and their use | |
HUP9601976A3 (en) | 4-fluoralkyl benzoylguanidines, process for producing them and pharmaceutical compositions containing these compounds | |
HU9503422D0 (en) | New compounds, pharmaceutical compositions containing them and process for producing them | |
HUP9600213A3 (en) | 4-mercapto-benzoyl-guanidine derivatives, process for producing them and pharmaceutical compositions containing them | |
HUP0004177A3 (en) | 4,5-diaryloxazole derivatives, pharmaceutical compositions containing them and process for producing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |