HUP9801680A2 - Peptidek és ezeket tartalmazó gyógyászati készítmények autoimmun betegségek kezelésére - Google Patents
Peptidek és ezeket tartalmazó gyógyászati készítmények autoimmun betegségek kezeléséreInfo
- Publication number
- HUP9801680A2 HUP9801680A2 HU9801680A HUP9801680A HUP9801680A2 HU P9801680 A2 HUP9801680 A2 HU P9801680A2 HU 9801680 A HU9801680 A HU 9801680A HU P9801680 A HUP9801680 A HU P9801680A HU P9801680 A2 HUP9801680 A2 HU P9801680A2
- Authority
- HU
- Hungary
- Prior art keywords
- amino acid
- peptides
- side chain
- independently represent
- acid residue
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 125000000539 amino acid group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004404 heteroalkyl group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010037660 Pyrexia Diseases 0.000 abstract 1
- 208000024780 Urticaria Diseases 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
A találmány tárgyát az alábbi aminősav-szekvenciával rendelkezőpeptidek vagy ezek származékai, vagy módősűlatai képezik: Ala-Xaa1-Leű-Xaa2-Phe-Xaa3-Xaa4-Xaa5-(Xaa6)n ahől Xaa1 és Xaa4 egymástól függetlenül egy őlyan aminősavma-radékőtjelent, amely egy alkil-vagy heterőalkilőldalláncőt tartalmazhat,amely egy hidrőxil-, aminő- vagy gűanidűlcsőpőrttal lehethelyettesítve, Xaa2 és Xaa6 egymástól függetlenül egy őlyan aminősavmaradékőt jelent,amely egy alkil- vay heterőalkil-őldalláncőt hőrdőzhat, amely egyhidrőxilcsőpőrttal lehet helyettesítve, Xaa3 és Xaa5 egymástól függetlenül egy őlyan aminősavmaradékőt jelent,amely egy hidrőfób őldalláncőt hőrdőzhat, és n értéke 1 vagy 0. A találmány szerinti peptidek és származékaikfelhasználhatók gyó- gyászati készítményként aűtőimműn betegek,szervátültetést kísérő ki-lökődéses főlyamat, gyűlladás és hasőnlókkezelésére és megelőzésére. ŕ
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11759295 | 1995-04-07 | ||
| JP7344649A JPH08333390A (ja) | 1995-04-07 | 1995-11-24 | ペプチド及びそれからなる自己免疫疾患治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9801680A2 true HUP9801680A2 (hu) | 1998-11-30 |
| HUP9801680A3 HUP9801680A3 (en) | 1999-06-28 |
Family
ID=26455689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9801680A HUP9801680A3 (en) | 1995-04-07 | 1996-04-03 | Peptides and remedy for autoimmune diseases comprising the same |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0821003B1 (hu) |
| JP (1) | JPH08333390A (hu) |
| KR (1) | KR19980703610A (hu) |
| CN (1) | CN1183784A (hu) |
| AT (1) | ATE247664T1 (hu) |
| AU (1) | AU704656B2 (hu) |
| CA (1) | CA2217679C (hu) |
| DE (1) | DE69629559T2 (hu) |
| ES (1) | ES2203685T3 (hu) |
| HU (1) | HUP9801680A3 (hu) |
| NO (1) | NO974566L (hu) |
| NZ (1) | NZ304437A (hu) |
| WO (1) | WO1996031529A1 (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6858210B1 (en) | 1998-06-09 | 2005-02-22 | La Jolla Pharmaceutical Co. | Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same |
| IL125262A0 (en) * | 1998-07-07 | 1999-03-12 | Yeda Res & Dev | Synthetic peptides and pharmaceutical compositions comprising them |
| US6913749B2 (en) | 1998-11-02 | 2005-07-05 | Resistentia Pharmaceuticals Ab | Immunogenic polypeptides for inducing anti-self IgE responses |
| US6935730B2 (en) | 2000-04-03 | 2005-08-30 | Unicorn Image Products Co. Ltd. Of Zhuhai | One-way valve, valve unit assembly, and ink cartridge using the same |
| EP1504102A2 (en) | 2002-05-21 | 2005-02-09 | Resistentia Pharmaceuticals AB | Chimeric ige polypeptides and host cells |
| CN1169829C (zh) | 2002-06-27 | 2004-10-06 | 北京大学人民医院 | 非t细胞结合肽及其用途 |
| US20110104186A1 (en) | 2004-06-24 | 2011-05-05 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
| WO2016190660A1 (ko) * | 2015-05-26 | 2016-12-01 | 주식회사 젬백스앤카엘 | 신규 펩티드 및 이를 포함한 조성물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2072356A1 (en) * | 1989-12-29 | 1991-06-30 | James L. Urban | Diagnosis and treatment of diseases |
| JP3516681B2 (ja) * | 1991-06-24 | 2004-04-05 | カイロン コーポレイション | Ｃ型肝炎ウイルス（ｈｃｖ）ポリペプチド |
| WO1993006135A1 (en) * | 1991-09-23 | 1993-04-01 | Genentech, Inc. | Diagnosing and treating autoimmune disorders |
| CA2144044A1 (en) * | 1992-09-14 | 1994-03-31 | The Brigham And Women's Hospital | Reagents and methods for treating rheumatoid arthritis |
-
1995
- 1995-11-24 JP JP7344649A patent/JPH08333390A/ja active Pending
-
1996
- 1996-04-03 CA CA002217679A patent/CA2217679C/en not_active Expired - Fee Related
- 1996-04-03 WO PCT/JP1996/000917 patent/WO1996031529A1/ja not_active Application Discontinuation
- 1996-04-03 CN CN96193769A patent/CN1183784A/zh active Pending
- 1996-04-03 DE DE69629559T patent/DE69629559T2/de not_active Expired - Lifetime
- 1996-04-03 NZ NZ304437A patent/NZ304437A/xx unknown
- 1996-04-03 HU HU9801680A patent/HUP9801680A3/hu unknown
- 1996-04-03 AU AU51622/96A patent/AU704656B2/en not_active Ceased
- 1996-04-03 AT AT96908337T patent/ATE247664T1/de not_active IP Right Cessation
- 1996-04-03 EP EP96908337A patent/EP0821003B1/en not_active Expired - Lifetime
- 1996-04-03 ES ES96908337T patent/ES2203685T3/es not_active Expired - Lifetime
- 1996-04-03 KR KR1019970707009A patent/KR19980703610A/ko not_active Application Discontinuation
-
1997
- 1997-10-02 NO NO974566A patent/NO974566L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU5162296A (en) | 1996-10-23 |
| EP0821003A1 (en) | 1998-01-28 |
| CN1183784A (zh) | 1998-06-03 |
| NO974566D0 (no) | 1997-10-02 |
| DE69629559T2 (de) | 2004-06-17 |
| MX9707662A (es) | 1997-11-29 |
| WO1996031529A1 (fr) | 1996-10-10 |
| CA2217679C (en) | 2008-03-25 |
| DE69629559D1 (de) | 2003-09-25 |
| AU704656B2 (en) | 1999-04-29 |
| EP0821003B1 (en) | 2003-08-20 |
| ES2203685T3 (es) | 2004-04-16 |
| KR19980703610A (ko) | 1998-12-05 |
| NO974566L (no) | 1997-11-26 |
| JPH08333390A (ja) | 1996-12-17 |
| CA2217679A1 (en) | 1996-10-10 |
| NZ304437A (en) | 1999-01-28 |
| ATE247664T1 (de) | 2003-09-15 |
| HUP9801680A3 (en) | 1999-06-28 |
| EP0821003A4 (en) | 2000-05-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5270150B2 (ja) | 細菌感染の治療 | |
| BRPI0507822A (pt) | método e composição farmacêutica para a prevenção ou o tratamento de uma doença ou uma condição autoimune ou infecciosa, método e composição farmacêutica para a prevenção ou o tratamento de uma doença ou uma condição do sangue, método e composição farmacêutica para modular a formação de células do sangue, método e composição farmacêutica para intensificar a mobilização periférico da célula tronco, método e composição farmacêutica para a prevenção ou o tratamento de uma doença ou uma condição metabólica, método e composição farmacêutica para a prevenção ou o tratamento das condições associadas com doses mieloablativas de quimioradioterapia suportadas pelo transplante autólogo de medula óssea ou de células tronco do sangue periférico (asct) ou pelo transplante alogenéico de medula óssea (bmt), método e composição farmacêutica para aumentar o efeito de um fator estimulante de células do sangue, método e composição farmacêutica para intensificar a colonização de células tronco do sangue doadas em um receptor mieloablatado, método e composição farmacêutica para a prevenção ou o tratamento de uma doença ou uma condição bacteriana, composição farmacêutica para o tratamento ou a prevenção de uma indicação selecionada do grupo que consiste em doença ou condição autoimune, doença viral, infecção viral, doença hematológica, deficiências hematológicas, trombocitopenia, pancitopenia, granulopenia, hiperlipidemia, hipercolesterolemia, glucosuria, hiperglicemia, diabetes, aids, hiv-1, distúrbios de células t auxiliares, deficiências de células dendrìticas, deficiências de macrofagos, distúrbios de células tronco hematopoiéticas incluindo distúrbios com plaquetas, linfócitos, células do plasma e neutrófilos, condições pré-leucêmicas, condições leucêmicas, distúrbios do sistema imunológico resultantes da terapia de quimioterapia ou de radiação, distúrbios do sistema imunológico humano resultantes do tratamento das doenças de deficiência imunológica e infecções bacterianas, composição farmacêutica para o tratamento ou a prevenção de um indicação selecionada do grupo que consiste em doença hematológica, deficiências hematológicas, trombocitopenia, pancitopenia, granulopenia, deficiências de células dendrìticas, deficiências de macrofagos, distúrbios de células tronco hematopoiéticas incluindo distúrbios com plaquetas, linfócitos, células do plasma e neutrófilos, condições pré-leucêmicas, condições leucêmicas, sìndrome mielodisplástiacas, malignidades não mielóides, anemia plástica e insuficiência da medula óssea, peptìdeo purificado, peptìdeo quimérico purificado, peptìdeo quimérico, composição farmacêutica, composição farmacêutica para a prevenção ou o tratamento de uma condição associada com um agente infeccioso de sars, método de processamento a baixa temperatura de hidrolisato proteolìtico de caseìna e hidrolisato de proteìna de caseìna | |
| ATE242633T1 (de) | Dialkylfumarate zur behandlung von autoimmunerkrankungen | |
| KR960703015A (ko) | 후천성 면역결핍증 치료용 약물의 제조시 노나- 및 데카펩타이드의 용도(Use of nona-and decapeptides in the preparation of a durg for the treatment of AIDS) | |
| GR3031919T3 (en) | PEPTIDES OF HUMAN p53 PROTEIN FOR USE IN HUMAN T CELL RESPONSE INDUCING COMPOSITIONS, AND HUMAN p53 PROTEIN-SPECIFIC CYTOTOXIC T-LYMPHOCYTES. | |
| PT689550E (pt) | Peptidos antimicrobianos de neutrofilos bovinos | |
| NO980195L (no) | Cyklosporinderivater med anti-HIV-effekt | |
| ATE108662T1 (de) | Antimikrobielle peptide, zusammensetzungen, die diese enthalten, und verwendungen daraus. | |
| ATE184598T1 (de) | Enniatine und enniatinderivate zur bekämpfung von endoparasiten | |
| AU7489687A (en) | Translation of mrna | |
| AU6020099A (en) | Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein | |
| HUP9801680A2 (hu) | Peptidek és ezeket tartalmazó gyógyászati készítmények autoimmun betegségek kezelésére | |
| EA027343B1 (ru) | Имплантируемые устройства медицинского назначения с повышенной иммунной толерантностью и способы изготовления и имплантирования | |
| ATE426402T1 (de) | Medizinische zusammensetzungen enthaltend 2-amino-2-a2-(4-octylphenyl)ethylupropan-1,3-di l | |
| CA2453112A1 (en) | New cationic peptides of the dermaseptin family isolated from the skin secretion of phyllomedusa hypochondrialls | |
| US4435384A (en) | Transfer factor composition and skin treatment | |
| PT1025849E (pt) | Metodos para deteccao e tratamento de individuos tendo celulas anormais que expressam antigenios do peptideo hla-a2/tirosinase | |
| Edelstein et al. | Studies on the in vitro spermicidal activity of synthetic magainins | |
| NO980300L (no) | Nye höymolekylære humane MP52 proteiner | |
| NO942360L (no) | Vaksine og polypeptider som er nyttige for denne | |
| ATE239502T1 (de) | Impfung mit peptiden von mhc klasse ii molekülen zur behandlung von autoimmunkrankheiten | |
| RU95120588A (ru) | Циклогексапептиды, их смеси, способ их получения и применения | |
| CA2404696A1 (en) | Medicament containing tissue inhibitor of metalloproteinases-2 (timp-2) as an osteoanabolically active substance | |
| ES2138668T3 (es) | Nuevos derivados de peptidos terapeuticamente activos en la cadena de coagulacion sanguinea, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| DE68913212D1 (de) | Ein reines faktor i-protein und verfahren zur herstellung. |