MX9707662A - Peptidas y agente terapeutico para enfermedades autoinmunes que contienen las mismas. - Google Patents

Peptidas y agente terapeutico para enfermedades autoinmunes que contienen las mismas.

Info

Publication number
MX9707662A
MX9707662A MX9707662A MX9707662A MX9707662A MX 9707662 A MX9707662 A MX 9707662A MX 9707662 A MX9707662 A MX 9707662A MX 9707662 A MX9707662 A MX 9707662A MX 9707662 A MX9707662 A MX 9707662A
Authority
MX
Mexico
Prior art keywords
amino acid
peptides
side chain
independently represent
acid residue
Prior art date
Application number
MX9707662A
Other languages
English (en)
Other versions
MXPA97007662A (es
Inventor
Nobuyuki Yamagata
Kenji Ogata
Masako Wagatsuma
Hitoshi Takanashi
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan filed Critical Hoechst Japan
Publication of MX9707662A publication Critical patent/MX9707662A/es
Publication of MXPA97007662A publication Critical patent/MXPA97007662A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invencion se relaciona con una peptida que tiene la siguiente secuencia de amino cido: Ala-Xaa1-Leu-Xaa2-Phe-Xaa3-Xaa4-Xaa5-(Xaa6)n (en donde Xaa1 y Xaa4 cada un representa independientemente un residuo de amino cido que puede tener una cadena lateral de alquilo o heteroalquilo que puede estar substituída por un grupo hidroxi, amino o guanidilo; Xaa2 y Xaa6 cada uno representa independientemente un residuo de amino cido que puede tener una cadena lateral de alquilo o heteroalquilo que puede estar substituída por un grupo hidroxilo; Xaa3 y Xaa5 cada un representa independientemente un residuo de amino cido que puede tener una cadena lateral hidrofobica; y n representa 1 o 0), o derivados de la misma y una modificacion de la misma. Los péptidos o derivados de la misma de conformidad con la presente invencion es ??til como una composicion francaéutica para la prevencion y tratamiento de enfermedades autoinmunes, reaccion de rechazo inherente en el trasplante de organo, inflamacion o lo semejante.
MXPA/A/1997/007662A 1995-04-07 1997-10-06 Peptidas y agente terapeutico para enfermedades autoinmunes que contienen las mismas MXPA97007662A (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP7-117592 1995-04-07
JP11759295 1995-04-07
JP7/117592 1995-04-07
JP7-344649 1995-11-24
JP7344649A JPH08333390A (ja) 1995-04-07 1995-11-24 ペプチド及びそれからなる自己免疫疾患治療剤
JP7/344649 1995-11-24
PCT/JP1996/000917 WO1996031529A1 (fr) 1995-04-07 1996-04-03 Peptides et medicaments contre les maladies auto-immunes contenant ces peptides

Publications (2)

Publication Number Publication Date
MX9707662A true MX9707662A (es) 1997-11-29
MXPA97007662A MXPA97007662A (es) 1998-07-03

Family

ID=

Also Published As

Publication number Publication date
JPH08333390A (ja) 1996-12-17
CN1183784A (zh) 1998-06-03
AU704656B2 (en) 1999-04-29
DE69629559T2 (de) 2004-06-17
WO1996031529A1 (fr) 1996-10-10
NO974566L (no) 1997-11-26
EP0821003A4 (en) 2000-05-24
ES2203685T3 (es) 2004-04-16
ATE247664T1 (de) 2003-09-15
DE69629559D1 (de) 2003-09-25
AU5162296A (en) 1996-10-23
NO974566D0 (no) 1997-10-02
CA2217679C (en) 2008-03-25
KR19980703610A (ko) 1998-12-05
HUP9801680A2 (hu) 1998-11-30
NZ304437A (en) 1999-01-28
EP0821003A1 (en) 1998-01-28
CA2217679A1 (en) 1996-10-10
HUP9801680A3 (en) 1999-06-28
EP0821003B1 (en) 2003-08-20

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