ATE239502T1 - Impfung mit peptiden von mhc klasse ii molekülen zur behandlung von autoimmunkrankheiten - Google Patents
Impfung mit peptiden von mhc klasse ii molekülen zur behandlung von autoimmunkrankheitenInfo
- Publication number
- ATE239502T1 ATE239502T1 AT94904861T AT94904861T ATE239502T1 AT E239502 T1 ATE239502 T1 AT E239502T1 AT 94904861 T AT94904861 T AT 94904861T AT 94904861 T AT94904861 T AT 94904861T AT E239502 T1 ATE239502 T1 AT E239502T1
- Authority
- AT
- Austria
- Prior art keywords
- peptides
- treatment
- mhc class
- vaccination
- molecules
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 102000018713 Histocompatibility Antigens Class II Human genes 0.000 title abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 108091054438 MHC class II family Proteins 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
- 108700018351 Major Histocompatibility Complex Proteins 0.000 abstract 3
- 230000028993 immune response Effects 0.000 abstract 3
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 abstract 3
- 102000003886 Glycoproteins Human genes 0.000 abstract 2
- 108090000288 Glycoproteins Proteins 0.000 abstract 2
- 230000002939 deleterious effect Effects 0.000 abstract 2
- 108700028369 Alleles Proteins 0.000 abstract 1
- 108010027412 Histocompatibility Antigens Class II Proteins 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 108091007491 NSP3 Papain-like protease domains Proteins 0.000 abstract 1
- 102000015636 Oligopeptides Human genes 0.000 abstract 1
- 108010038807 Oligopeptides Proteins 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000005784 autoimmunity Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99294292A | 1992-12-17 | 1992-12-17 | |
| PCT/US1993/012351 WO1994013320A1 (en) | 1992-12-17 | 1993-12-16 | Vaccination with peptide of mhc class ii molecules for treatment of autoimmune disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239502T1 true ATE239502T1 (de) | 2003-05-15 |
Family
ID=25538911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94904861T ATE239502T1 (de) | 1992-12-17 | 1993-12-16 | Impfung mit peptiden von mhc klasse ii molekülen zur behandlung von autoimmunkrankheiten |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0674526B1 (de) |
| JP (1) | JPH08509204A (de) |
| AT (1) | ATE239502T1 (de) |
| AU (1) | AU5872594A (de) |
| CA (1) | CA2152075C (de) |
| DE (1) | DE69332956D1 (de) |
| WO (1) | WO1994013320A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6045796A (en) * | 1992-12-17 | 2000-04-04 | Anergen, Inc. | Vaccination with peptide of MHC class II molecules for treatment of autoimmune disease |
| EP0723458A4 (de) * | 1994-06-16 | 1998-03-11 | Univ Leland Stanford Junior | Die immunmodulation mittels fragmenten der klasse ii-alpha-untereinheit |
| IT1274592B (it) * | 1994-08-05 | 1997-07-18 | Angela Turiano | Composizione farmaceutica per la terapia tumorale contenente xenoantigeni |
| US20030118594A1 (en) * | 1995-06-07 | 2003-06-26 | Bishwajit Nag | Stable formulations of mhc-peptide complexes |
| WO2000061632A1 (en) * | 1999-04-12 | 2000-10-19 | Stanford University | Interaction of mhc class ii proteins with members of the pcna family of proteins |
| EP1715343B1 (de) * | 2005-04-20 | 2009-12-09 | F. Hoffmann-La Roche Ag | Verfahren zur Identifizierung von Epitopen in Zusammenhang mit Immunogenität bei Biopharmazeutika |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1327162C (en) * | 1987-04-09 | 1994-02-22 | Board Of Trustees Of The Leland Stanford Junior University (The) | Method for prophylactically treating an individual for an autoimmune disease |
| JPH06507630A (ja) * | 1991-03-22 | 1994-09-01 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルベニア | 哺乳類ｔ細胞の応答を調節する方法 |
-
1993
- 1993-12-16 AU AU58725/94A patent/AU5872594A/en not_active Abandoned
- 1993-12-16 AT AT94904861T patent/ATE239502T1/de not_active IP Right Cessation
- 1993-12-16 CA CA002152075A patent/CA2152075C/en not_active Expired - Fee Related
- 1993-12-16 DE DE69332956T patent/DE69332956D1/de not_active Expired - Lifetime
- 1993-12-16 WO PCT/US1993/012351 patent/WO1994013320A1/en not_active Ceased
- 1993-12-16 JP JP6514538A patent/JPH08509204A/ja not_active Ceased
- 1993-12-16 EP EP94904861A patent/EP0674526B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2152075A1 (en) | 1994-06-23 |
| EP0674526B1 (de) | 2003-05-07 |
| DE69332956D1 (de) | 2003-06-12 |
| EP0674526A1 (de) | 1995-10-04 |
| CA2152075C (en) | 2001-04-10 |
| EP0674526A4 (de) | 1997-01-15 |
| JPH08509204A (ja) | 1996-10-01 |
| AU5872594A (en) | 1994-07-04 |
| WO1994013320A1 (en) | 1994-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |