HUP9800976A2 - 3-Fenil-1,4-dialkil-1,2,4-triazolium-sók és az ezeket tartalmazó gyógyszerkészítmények - Google Patents

3-Fenil-1,4-dialkil-1,2,4-triazolium-sók és az ezeket tartalmazó gyógyszerkészítmények

Info

Publication number
HUP9800976A2
HUP9800976A2 HU9800976A HUP9800976A HUP9800976A2 HU P9800976 A2 HUP9800976 A2 HU P9800976A2 HU 9800976 A HU9800976 A HU 9800976A HU P9800976 A HUP9800976 A HU P9800976A HU P9800976 A2 HUP9800976 A2 HU P9800976A2
Authority
HU
Hungary
Prior art keywords
dialkyl
phenyl
pharmaceutical compositions
compositions containing
fluorocarbon
Prior art date
Application number
HU9800976A
Other languages
English (en)
Inventor
Christopher R. Dalton
John M. Kane
John H. Kehne
Original Assignee
Hoechst Marion Roussel, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel, Inc. filed Critical Hoechst Marion Roussel, Inc.
Publication of HUP9800976A2 publication Critical patent/HUP9800976A2/hu
Publication of HUP9800976A3 publication Critical patent/HUP9800976A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány tárgyát az (I) általánős képletű vegyületek, és az ezekettartalmazó gyógyszerkészítmények képezik. Az (I) általánős képletben R jelentése halőgénatőm, triflűőr-metil-csőpőrt, 1-4 szénatőmszámúalkilcsőpőrt, vagy 1-4 szénatőmszámú alkőxicsőpőrt; n jelentése 0, 1 vagy 2; R1 és R4 jelentése egymástól függetlenül 1-3 szénatőmszámúalkilcsőpőrt; és A jelentése valamely gyógyászatilag elfőgadható aniőn. A találmányszerinti vegyületek antidepresszáns hatással rendelkeznek. ŕ
HU9800976A 1995-04-20 1996-03-22 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and pharmaceutical compositions containing them HUP9800976A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42674495A 1995-04-20 1995-04-20

Publications (2)

Publication Number Publication Date
HUP9800976A2 true HUP9800976A2 (hu) 1998-08-28
HUP9800976A3 HUP9800976A3 (en) 2000-07-28

Family

ID=23692036

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800976A HUP9800976A3 (en) 1995-04-20 1996-03-22 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US5856350A (hu)
EP (1) EP0821676B1 (hu)
JP (1) JP3717185B2 (hu)
KR (1) KR100385380B1 (hu)
CN (1) CN1182422A (hu)
AR (1) AR002733A1 (hu)
AT (1) ATE194334T1 (hu)
AU (1) AU704798B2 (hu)
CA (1) CA2216787C (hu)
DE (1) DE69609172T2 (hu)
DK (1) DK0821676T3 (hu)
ES (1) ES2149463T3 (hu)
GR (1) GR3034345T3 (hu)
HU (1) HUP9800976A3 (hu)
IL (1) IL117941A0 (hu)
MX (1) MX9708031A (hu)
NO (1) NO974810L (hu)
NZ (1) NZ305657A (hu)
PT (1) PT821676E (hu)
TW (1) TW362097B (hu)
WO (1) WO1996033177A1 (hu)
ZA (1) ZA962983B (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6362342B1 (en) * 1999-06-29 2002-03-26 Lion Bioscience Ag Triazole compounds and methods of making same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1481761A (fr) * 1965-06-03 1967-05-19 Basf Ag Sels de triazolium et procédé pour leur préparation
JPS5063119A (hu) * 1973-10-05 1975-05-29
US4230715A (en) * 1979-09-04 1980-10-28 Richardson-Merrell Inc. 1,2,4-Triazole-3-thiols as antisecretory agents
EP0036711B1 (en) * 1980-03-22 1985-12-04 Fbc Limited Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use
DD205549A1 (de) * 1982-06-23 1983-12-28 Wolfen Filmfab Veb Diazotypiematerial
US4775688A (en) * 1985-12-11 1988-10-04 Merrell Dow Pharmaceuticals Inc. 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and their use as antidepressants
US5436252A (en) * 1986-12-19 1995-07-25 Merrell Dow Pharmaceuticals Inc. 5-aryl-3H-1,2,4-triazol-3-ones and their use in the treatment of neurodegenerative disorders
US4946856A (en) * 1986-12-19 1990-08-07 Merrell Dow Pharmaceuticals Inc. 5-phenyl-3H-1,2,4-triazol-3-ones and their use as anticonvulsants
US5158968A (en) * 1987-01-27 1992-10-27 Merrell Dow Pharmaceuticals Inc. 3-aryl-5-alkylthio-4H-1,2,4-traizoles for treatment of hyperreflexia due to spinal trauma
US4981863A (en) * 1987-01-27 1991-01-01 Merrell Dow Pharmaceuticals 3-aryl-5-alkylthio-4H-1,2,4-triazoles
US5143933A (en) * 1987-01-27 1992-09-01 Merrell Dow Pharmaceuticals Inc. 3-aryl-5-alkylthio-4H-1,2,4-triazoles
US4847276A (en) * 1988-09-06 1989-07-11 Merrell Dow Pharmaceuticals Inc. Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione
US4966909A (en) * 1989-12-20 1990-10-30 Merrell Dow Pharmaceuticals 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants
US5331002A (en) * 1990-04-19 1994-07-19 Merrell Dow Pharmaceuticals Inc. 5-aryl-4-alkyl-3H-1,2,4-triazole-3-thiones useful as memory enhancers
DE4230466A1 (de) * 1992-09-11 1994-03-17 Basf Ag Verfahren zur katalytischen Herstellung von Kondensationsprodukten des Formaldehyds

Also Published As

Publication number Publication date
JPH11503759A (ja) 1999-03-30
JP3717185B2 (ja) 2005-11-16
KR100385380B1 (ko) 2003-10-10
TW362097B (en) 1999-06-21
ES2149463T3 (es) 2000-11-01
PT821676E (pt) 2000-10-31
CN1182422A (zh) 1998-05-20
US5856350A (en) 1999-01-05
NO974810L (no) 1997-12-18
CA2216787C (en) 2001-05-22
MX9708031A (es) 1997-11-29
CA2216787A1 (en) 1996-10-24
GR3034345T3 (en) 2000-12-29
ZA962983B (en) 1996-10-22
WO1996033177A1 (en) 1996-10-24
KR19990007807A (ko) 1999-01-25
IL117941A0 (en) 1996-08-04
AU704798B2 (en) 1999-05-06
EP0821676B1 (en) 2000-07-05
HUP9800976A3 (en) 2000-07-28
DE69609172D1 (de) 2000-08-10
EP0821676A1 (en) 1998-02-04
DK0821676T3 (da) 2000-11-20
ATE194334T1 (de) 2000-07-15
AU5371996A (en) 1996-11-07
DE69609172T2 (de) 2001-03-22
NZ305657A (en) 1998-05-27
NO974810D0 (no) 1997-10-17
AR002733A1 (es) 1998-04-29

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