ES2149463T3 - Sales de 3-fenil-1,4-dialquil-1,2,4-triazolio y su utilizacion como antidepresores. - Google Patents

Sales de 3-fenil-1,4-dialquil-1,2,4-triazolio y su utilizacion como antidepresores.

Info

Publication number
ES2149463T3
ES2149463T3 ES96910552T ES96910552T ES2149463T3 ES 2149463 T3 ES2149463 T3 ES 2149463T3 ES 96910552 T ES96910552 T ES 96910552T ES 96910552 T ES96910552 T ES 96910552T ES 2149463 T3 ES2149463 T3 ES 2149463T3
Authority
ES
Spain
Prior art keywords
sub
antidepressants
dialkyl
phenyl
triazole salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96910552T
Other languages
English (en)
Inventor
Christopher R Dalton
John M Kane
John H Kehne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2149463T3 publication Critical patent/ES2149463T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Abstract

ESTA INVENCION TRATA DEL TRATAMIENTO DE LA DEPRESION MEDIANTE LA ADMINISTRACION DE NUEVAS SALES DE 3 ES HALOGENO, TRIFLUOROMETILO, ALQUILO INFERIOR C SUB,1-4} O ALCOXI INFERIOR C SUB,1-4}, N ES CERO, 1 O 2, Y R SUB,1} Y R SUB,4} REPRESENTAN INDEPENDIENTEMENTE ALQUILO INFERIOR C SUB,1-3}; Y A SUP,-} REPRESENTA UN ANION FARMACEUTICAMENTE ACEPTABLE.
ES96910552T 1995-04-20 1996-03-22 Sales de 3-fenil-1,4-dialquil-1,2,4-triazolio y su utilizacion como antidepresores. Expired - Lifetime ES2149463T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42674495A 1995-04-20 1995-04-20

Publications (1)

Publication Number Publication Date
ES2149463T3 true ES2149463T3 (es) 2000-11-01

Family

ID=23692036

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96910552T Expired - Lifetime ES2149463T3 (es) 1995-04-20 1996-03-22 Sales de 3-fenil-1,4-dialquil-1,2,4-triazolio y su utilizacion como antidepresores.

Country Status (22)

Country Link
US (1) US5856350A (es)
EP (1) EP0821676B1 (es)
JP (1) JP3717185B2 (es)
KR (1) KR100385380B1 (es)
CN (1) CN1182422A (es)
AR (1) AR002733A1 (es)
AT (1) ATE194334T1 (es)
AU (1) AU704798B2 (es)
CA (1) CA2216787C (es)
DE (1) DE69609172T2 (es)
DK (1) DK0821676T3 (es)
ES (1) ES2149463T3 (es)
GR (1) GR3034345T3 (es)
HU (1) HUP9800976A3 (es)
IL (1) IL117941A0 (es)
MX (1) MX9708031A (es)
NO (1) NO974810L (es)
NZ (1) NZ305657A (es)
PT (1) PT821676E (es)
TW (1) TW362097B (es)
WO (1) WO1996033177A1 (es)
ZA (1) ZA962983B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6362342B1 (en) * 1999-06-29 2002-03-26 Lion Bioscience Ag Triazole compounds and methods of making same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1481761A (fr) * 1965-06-03 1967-05-19 Basf Ag Sels de triazolium et procédé pour leur préparation
JPS5063119A (es) * 1973-10-05 1975-05-29
US4230715A (en) * 1979-09-04 1980-10-28 Richardson-Merrell Inc. 1,2,4-Triazole-3-thiols as antisecretory agents
EP0036711B1 (en) * 1980-03-22 1985-12-04 Fbc Limited Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use
DD205549A1 (de) * 1982-06-23 1983-12-28 Wolfen Filmfab Veb Diazotypiematerial
US4775688A (en) * 1985-12-11 1988-10-04 Merrell Dow Pharmaceuticals Inc. 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and their use as antidepressants
US4946856A (en) * 1986-12-19 1990-08-07 Merrell Dow Pharmaceuticals Inc. 5-phenyl-3H-1,2,4-triazol-3-ones and their use as anticonvulsants
US5436252A (en) * 1986-12-19 1995-07-25 Merrell Dow Pharmaceuticals Inc. 5-aryl-3H-1,2,4-triazol-3-ones and their use in the treatment of neurodegenerative disorders
US5143933A (en) * 1987-01-27 1992-09-01 Merrell Dow Pharmaceuticals Inc. 3-aryl-5-alkylthio-4H-1,2,4-triazoles
US4981863A (en) * 1987-01-27 1991-01-01 Merrell Dow Pharmaceuticals 3-aryl-5-alkylthio-4H-1,2,4-triazoles
US5158968A (en) * 1987-01-27 1992-10-27 Merrell Dow Pharmaceuticals Inc. 3-aryl-5-alkylthio-4H-1,2,4-traizoles for treatment of hyperreflexia due to spinal trauma
US4847276A (en) * 1988-09-06 1989-07-11 Merrell Dow Pharmaceuticals Inc. Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione
US4966909A (en) * 1989-12-20 1990-10-30 Merrell Dow Pharmaceuticals 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants
US5331002A (en) * 1990-04-19 1994-07-19 Merrell Dow Pharmaceuticals Inc. 5-aryl-4-alkyl-3H-1,2,4-triazole-3-thiones useful as memory enhancers
DE4230466A1 (de) * 1992-09-11 1994-03-17 Basf Ag Verfahren zur katalytischen Herstellung von Kondensationsprodukten des Formaldehyds

Also Published As

Publication number Publication date
NO974810L (no) 1997-12-18
DK0821676T3 (da) 2000-11-20
EP0821676B1 (en) 2000-07-05
HUP9800976A2 (hu) 1998-08-28
IL117941A0 (en) 1996-08-04
PT821676E (pt) 2000-10-31
HUP9800976A3 (en) 2000-07-28
US5856350A (en) 1999-01-05
NZ305657A (en) 1998-05-27
WO1996033177A1 (en) 1996-10-24
GR3034345T3 (en) 2000-12-29
KR19990007807A (ko) 1999-01-25
KR100385380B1 (ko) 2003-10-10
CN1182422A (zh) 1998-05-20
AU704798B2 (en) 1999-05-06
EP0821676A1 (en) 1998-02-04
TW362097B (en) 1999-06-21
MX9708031A (es) 1997-11-29
DE69609172T2 (de) 2001-03-22
ZA962983B (en) 1996-10-22
JP3717185B2 (ja) 2005-11-16
JPH11503759A (ja) 1999-03-30
ATE194334T1 (de) 2000-07-15
AR002733A1 (es) 1998-04-29
CA2216787C (en) 2001-05-22
CA2216787A1 (en) 1996-10-24
AU5371996A (en) 1996-11-07
DE69609172D1 (de) 2000-08-10
NO974810D0 (no) 1997-10-17

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