ZA962983B - 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants - Google Patents

3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants

Info

Publication number
ZA962983B
ZA962983B ZA962983A ZA962983A ZA962983B ZA 962983 B ZA962983 B ZA 962983B ZA 962983 A ZA962983 A ZA 962983A ZA 962983 A ZA962983 A ZA 962983A ZA 962983 B ZA962983 B ZA 962983B
Authority
ZA
South Africa
Prior art keywords
antidepressants
dialkyl
phenyl
triazolium salts
triazolium
Prior art date
Application number
ZA962983A
Inventor
Christopher Robin Dalton
John Michael Kane
John Herr Kehne
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of ZA962983B publication Critical patent/ZA962983B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA962983A 1995-04-20 1996-04-15 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants ZA962983B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42674495A 1995-04-20 1995-04-20

Publications (1)

Publication Number Publication Date
ZA962983B true ZA962983B (en) 1996-10-22

Family

ID=23692036

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA962983A ZA962983B (en) 1995-04-20 1996-04-15 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants

Country Status (22)

Country Link
US (1) US5856350A (en)
EP (1) EP0821676B1 (en)
JP (1) JP3717185B2 (en)
KR (1) KR100385380B1 (en)
CN (1) CN1182422A (en)
AR (1) AR002733A1 (en)
AT (1) ATE194334T1 (en)
AU (1) AU704798B2 (en)
CA (1) CA2216787C (en)
DE (1) DE69609172T2 (en)
DK (1) DK0821676T3 (en)
ES (1) ES2149463T3 (en)
GR (1) GR3034345T3 (en)
HU (1) HUP9800976A3 (en)
IL (1) IL117941A0 (en)
MX (1) MX9708031A (en)
NO (1) NO974810L (en)
NZ (1) NZ305657A (en)
PT (1) PT821676E (en)
TW (1) TW362097B (en)
WO (1) WO1996033177A1 (en)
ZA (1) ZA962983B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6362342B1 (en) * 1999-06-29 2002-03-26 Lion Bioscience Ag Triazole compounds and methods of making same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1481761A (en) * 1965-06-03 1967-05-19 Basf Ag Triazolium salts and process for their preparation
JPS5063119A (en) * 1973-10-05 1975-05-29
US4230715A (en) * 1979-09-04 1980-10-28 Richardson-Merrell Inc. 1,2,4-Triazole-3-thiols as antisecretory agents
EP0036711B1 (en) * 1980-03-22 1985-12-04 Fbc Limited Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use
DD205549A1 (en) * 1982-06-23 1983-12-28 Wolfen Filmfab Veb diazotype
US4775688A (en) * 1985-12-11 1988-10-04 Merrell Dow Pharmaceuticals Inc. 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and their use as antidepressants
US4946856A (en) * 1986-12-19 1990-08-07 Merrell Dow Pharmaceuticals Inc. 5-phenyl-3H-1,2,4-triazol-3-ones and their use as anticonvulsants
US5436252A (en) * 1986-12-19 1995-07-25 Merrell Dow Pharmaceuticals Inc. 5-aryl-3H-1,2,4-triazol-3-ones and their use in the treatment of neurodegenerative disorders
US4981863A (en) * 1987-01-27 1991-01-01 Merrell Dow Pharmaceuticals 3-aryl-5-alkylthio-4H-1,2,4-triazoles
US5158968A (en) * 1987-01-27 1992-10-27 Merrell Dow Pharmaceuticals Inc. 3-aryl-5-alkylthio-4H-1,2,4-traizoles for treatment of hyperreflexia due to spinal trauma
US5143933A (en) * 1987-01-27 1992-09-01 Merrell Dow Pharmaceuticals Inc. 3-aryl-5-alkylthio-4H-1,2,4-triazoles
US4847276A (en) * 1988-09-06 1989-07-11 Merrell Dow Pharmaceuticals Inc. Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione
US4966909A (en) * 1989-12-20 1990-10-30 Merrell Dow Pharmaceuticals 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants
US5331002A (en) * 1990-04-19 1994-07-19 Merrell Dow Pharmaceuticals Inc. 5-aryl-4-alkyl-3H-1,2,4-triazole-3-thiones useful as memory enhancers
DE4230466A1 (en) * 1992-09-11 1994-03-17 Basf Ag Process for the catalytic production of condensation products of formaldehyde

Also Published As

Publication number Publication date
PT821676E (en) 2000-10-31
TW362097B (en) 1999-06-21
EP0821676B1 (en) 2000-07-05
KR100385380B1 (en) 2003-10-10
CA2216787C (en) 2001-05-22
AU5371996A (en) 1996-11-07
DE69609172D1 (en) 2000-08-10
ATE194334T1 (en) 2000-07-15
NZ305657A (en) 1998-05-27
HUP9800976A2 (en) 1998-08-28
DE69609172T2 (en) 2001-03-22
DK0821676T3 (en) 2000-11-20
JP3717185B2 (en) 2005-11-16
GR3034345T3 (en) 2000-12-29
JPH11503759A (en) 1999-03-30
IL117941A0 (en) 1996-08-04
AR002733A1 (en) 1998-04-29
MX9708031A (en) 1997-11-29
CA2216787A1 (en) 1996-10-24
WO1996033177A1 (en) 1996-10-24
HUP9800976A3 (en) 2000-07-28
NO974810D0 (en) 1997-10-17
NO974810L (en) 1997-12-18
AU704798B2 (en) 1999-05-06
US5856350A (en) 1999-01-05
KR19990007807A (en) 1999-01-25
ES2149463T3 (en) 2000-11-01
EP0821676A1 (en) 1998-02-04
CN1182422A (en) 1998-05-20

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