HUP9702459A3 - Fused tricyclic diazepine and quinoxaline derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents
Fused tricyclic diazepine and quinoxaline derivatives, process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- HUP9702459A3 HUP9702459A3 HU9702459A HUP9702459A HUP9702459A3 HU P9702459 A3 HUP9702459 A3 HU P9702459A3 HU 9702459 A HU9702459 A HU 9702459A HU P9702459 A HUP9702459 A HU P9702459A HU P9702459 A3 HUP9702459 A3 HU P9702459A3
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- quinoxaline derivatives
- fused tricyclic
- Prior art date
Links
- LRANPJDWHYRCER-UHFFFAOYSA-N 1,2-diazepine Chemical compound N1C=CC=CC=N1 LRANPJDWHYRCER-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000001567 quinoxalinyl group Chemical class N1=C(C=NC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/373,125 US5521173A (en) | 1995-01-17 | 1995-01-17 | Tricyclic benzazepine vasopressin antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9702459A2 HUP9702459A2 (hu) | 1998-05-28 |
HUP9702459A3 true HUP9702459A3 (en) | 2000-08-28 |
Family
ID=23471074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9702459A HUP9702459A3 (en) | 1995-01-17 | 1996-01-16 | Fused tricyclic diazepine and quinoxaline derivatives, process for their preparation and pharmaceutical compositions containing them |
Country Status (24)
Country | Link |
---|---|
US (2) | US5521173A (hu) |
EP (1) | EP0805813B1 (hu) |
JP (2) | JP4156664B2 (hu) |
CN (1) | CN1052725C (hu) |
AR (1) | AR002021A1 (hu) |
AT (1) | ATE217625T1 (hu) |
AU (1) | AU707881B2 (hu) |
BR (1) | BR9607177A (hu) |
CA (1) | CA2210708C (hu) |
CZ (1) | CZ224797A3 (hu) |
DE (1) | DE69621225T2 (hu) |
DK (1) | DK0805813T3 (hu) |
EA (1) | EA000056B1 (hu) |
ES (1) | ES2175066T3 (hu) |
HK (1) | HK1003891A1 (hu) |
HU (1) | HUP9702459A3 (hu) |
IL (1) | IL116774A (hu) |
MX (1) | MX9705414A (hu) |
NZ (1) | NZ301198A (hu) |
PT (1) | PT805813E (hu) |
TW (1) | TW472056B (hu) |
UA (1) | UA48960C2 (hu) |
WO (1) | WO1996022292A1 (hu) |
ZA (1) | ZA96303B (hu) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5736540A (en) * | 1993-07-29 | 1998-04-07 | American Cyanamid Company | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists |
US5753648A (en) * | 1995-01-17 | 1998-05-19 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
US5700796A (en) * | 1995-01-17 | 1997-12-23 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
US5880122A (en) * | 1996-11-01 | 1999-03-09 | American Home Products Corporation | 3-Carboxamide derivatives of 5H-pyrrolo 2,1-c! 1,4!-benzodiazepines |
AU732214C (en) | 1997-03-31 | 2001-10-25 | Wakamoto Pharmaceutical Co., Ltd. | Biphenyl derivatives and drug composition |
US6194407B1 (en) | 1997-07-30 | 2001-02-27 | American Home Products Corporation | Tricyclic pyrido vasopressin agonists |
US6511974B1 (en) | 1997-07-30 | 2003-01-28 | Wyeth | Tricyclic vasopressin agonists |
EP1000062B1 (en) * | 1997-07-30 | 2004-09-22 | Wyeth | Tricyclic vasopressin agonists |
US7138393B2 (en) * | 1998-07-24 | 2006-11-21 | Wyeth | Biologically active vasopressin agonist metabolites |
US6090803A (en) * | 1998-07-24 | 2000-07-18 | American Home Products Corporation | Tricyclic vasopressin agonists |
HU229074B1 (en) | 1999-01-19 | 2013-07-29 | Ortho Mcneil Pharm Inc | Tricyclic benzodiazepines as vasopressin receptor antagonists |
CA2358891A1 (en) * | 1999-02-04 | 2000-08-10 | Amedeo Arturo Failli | Thienylbenzoylbenzazepines as vasopressin agonists |
US6235900B1 (en) | 1999-02-04 | 2001-05-22 | American Home Products Corporation | Tricyclic pyridine N-oxides vasopressin agonists |
US6620807B1 (en) | 1999-02-04 | 2003-09-16 | Wyeth | Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists |
US6344451B1 (en) | 1999-02-04 | 2002-02-05 | American Home Products | Pyrrolobenzodiazepine carboxyamide vasopressin agonists |
US6297234B1 (en) * | 1999-02-04 | 2001-10-02 | American Home Products Corporation | Arylthiophene vasopressin agonists |
JP2003510280A (ja) * | 1999-09-27 | 2003-03-18 | アメリカン・サイアナミド・カンパニー | バソプレッシンアゴニスト処方および製法 |
EP1829861A3 (en) * | 2001-03-20 | 2009-01-21 | Laboratoires Serono SA | Pyrrolidine ester derivatives active as oxytocin antagonists |
WO2002083145A1 (en) * | 2001-04-12 | 2002-10-24 | Wyeth | N-biphenylcarbonyl- and n-phenylpyridylcarbonyl substituted bi- and tricyclic azepines and diazepines as vasopressing agonists |
US6900200B2 (en) * | 2001-04-12 | 2005-05-31 | Wyeth | Tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists |
US7202239B2 (en) * | 2001-04-12 | 2007-04-10 | Wyeth | Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists |
US7109193B2 (en) | 2001-04-12 | 2006-09-19 | Wyeth | Tricyclic diazepines tocolytic oxytocin receptor antagonists |
US7326700B2 (en) * | 2001-04-12 | 2008-02-05 | Wyeth | Cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists |
US7064120B2 (en) * | 2001-04-12 | 2006-06-20 | Wyeth | Tricyclic pyridyl carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists |
US6977254B2 (en) * | 2001-04-12 | 2005-12-20 | Wyeth | Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists |
US6903087B2 (en) * | 2001-04-12 | 2005-06-07 | Wyeth | Pyrido cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists |
US7022699B2 (en) * | 2001-04-12 | 2006-04-04 | Wyeth | Cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators |
EP1381608B1 (en) * | 2001-04-12 | 2007-10-10 | Wyeth | Cyclohexylphenyl vasopressin agonists |
CA2465497A1 (en) * | 2001-10-29 | 2003-05-08 | Ortho-Mcneil Pharmaceutical, Inc. | Bridged bicyclic amino acid-derived (1,4) benzodiazepine vasopressin receptor antagonists |
US7119088B2 (en) * | 2003-02-19 | 2006-10-10 | Pfizer Inc. | Triazole compounds useful in therapy |
EP2061795B1 (en) * | 2006-08-14 | 2014-01-15 | Council of Scientific & Industrial Research | Pyrrolo[2,1-c][1,4]benzodiazepine hybrids and a process for the preparation thereof |
CN102118968A (zh) * | 2008-06-10 | 2011-07-06 | 雅培制药有限公司 | 新的三环化合物 |
KR101348499B1 (ko) | 2008-11-13 | 2014-01-06 | 에프. 호프만-라 로슈 아게 | 스피로-5,6-다이하이드로-4h-2,3,5,10b-테트라아자-벤조〔e〕아줄렌 |
PL2358714T3 (pl) | 2008-11-18 | 2012-12-31 | Hoffmann La Roche | Etery alkilocykloheksylowe dihydrotetraazabenzoazulenu |
UA103504C2 (ru) | 2008-11-28 | 2013-10-25 | Ф. Хоффманн-Ля Рош Аг | Арилциклогексилэфиры дигидротетраазабензоазуленов для применения как антагонистов рецептора вазопрессина v1a |
RU2012127368A (ru) | 2009-12-01 | 2014-01-10 | Эбботт Лэборетриз | Новые трициклические соединения |
WO2011068881A1 (en) | 2009-12-01 | 2011-06-09 | Abbott Laboratories | Novel tricyclic compounds |
US8420633B2 (en) | 2010-03-31 | 2013-04-16 | Hoffmann-La Roche Inc. | Aryl-cyclohexyl-tetraazabenzo[e]azulenes |
US8461151B2 (en) | 2010-04-13 | 2013-06-11 | Hoffmann-La Roche Inc. | Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes |
US8492376B2 (en) | 2010-04-21 | 2013-07-23 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes |
US8481528B2 (en) | 2010-04-26 | 2013-07-09 | Hoffmann-La Roche Inc. | Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes |
US9199976B2 (en) | 2010-06-01 | 2015-12-01 | The University Of Queensland | Haematopoietic-prostaglandin D2 synthase inhibitors |
CN103288829A (zh) * | 2012-02-24 | 2013-09-11 | 中国科学院大连化学物理研究所 | 一种合成手性二氢-5H-吡咯并[2,1-c][1,4]-苯并二氮杂卓-5-酮的方法 |
WO2014060381A1 (de) | 2012-10-18 | 2014-04-24 | Bayer Cropscience Ag | Heterocyclische verbindungen als schädlingsbekämpfungsmittel |
WO2014067962A1 (de) | 2012-10-31 | 2014-05-08 | Bayer Cropscience Ag | Neue heterocylische verbindungen als schädlingsbekämpfungsmittel |
CA2905993C (en) | 2013-03-14 | 2022-12-06 | Tolero Pharmaceuticals, Inc. | Substituted 4-amino-pyrimidinyl-2-amino-phenyl derivatives and pharmaceutical compositions thereof for use as jak2 and alk2 inhibitors |
US11512092B2 (en) | 2015-10-16 | 2022-11-29 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
US11524964B2 (en) | 2015-10-16 | 2022-12-13 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
US11365198B2 (en) | 2015-10-16 | 2022-06-21 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
CN116270645A (zh) | 2015-10-16 | 2023-06-23 | 艾伯维公司 | 制备咪唑并[1,2-a]吡咯并[2,3-e]吡嗪类化合物及其固态形式的方法 |
US10550126B2 (en) | 2015-10-16 | 2020-02-04 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
US11780848B2 (en) | 2015-10-16 | 2023-10-10 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1- carboxamide and solid state forms thereof |
US11040038B2 (en) | 2018-07-26 | 2021-06-22 | Sumitomo Dainippon Pharma Oncology, Inc. | Methods for treating diseases associated with abnormal ACVR1 expression and ACVR1 inhibitors for use in the same |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3763183A (en) * | 1972-07-10 | 1973-10-02 | Sterling Drug Inc | 1,2,3,10,11,11a-hexahydro-5h-pyrrolo (2,1-c)(1,4)benzodiazepines |
US4766108A (en) * | 1986-12-04 | 1988-08-23 | Smith Kline Beckman Corporation | Tyr-Arg-vasopressin antagonists |
US5055448A (en) * | 1987-06-25 | 1991-10-08 | Medical College Of Ohio | Linear derivatives of arginine vasopressin antagonists |
DK0382185T3 (da) * | 1989-02-10 | 1994-07-04 | Otsuka Pharma Co Ltd | Carbostyrilderivater |
US5258510A (en) * | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
ES2089033T3 (es) * | 1989-10-20 | 1996-10-01 | Otsuka Pharma Co Ltd | Compuestos benzoheterociclicos. |
US5070187A (en) * | 1989-11-03 | 1991-12-03 | Trustees Of Boston University | Pharmacologically effective antagonists of arginine-vasopressin |
TW199153B (hu) * | 1990-08-07 | 1993-02-01 | Dtsuka Seiyaku Kk | |
TW198715B (hu) * | 1991-04-19 | 1993-01-21 | Dtsuka Seiyaku Kk | |
US5204349A (en) * | 1991-09-16 | 1993-04-20 | Merck & Co., Inc. | Amide-substituted derivatives of spiroindanylcamphorsulfonyl oxytocin antagonists |
EP0533240A3 (en) * | 1991-09-16 | 1993-09-29 | Merck & Co. Inc. | Substituted amine derivatives of piperazinylcamphorsulfonyl oxytocin antagonists |
DE69223573D1 (de) * | 1991-09-16 | 1998-01-29 | Merck & Co Inc | Hydantoin und Succinimid-substituierte Spiroindanylcamphorsulfonyl als Oxytocin-Antagonisten |
EP0533242A3 (en) * | 1991-09-16 | 1993-09-15 | Merck & Co. Inc. | Substituted derivatives of piperazinylcamphorsulfonyl oxytocin antagonists |
TW250481B (hu) * | 1992-08-20 | 1995-07-01 | Otsuka Pharma Co Ltd | |
AU5533894A (en) * | 1992-11-25 | 1994-06-22 | Yamanouchi Pharmaceutical Co., Ltd. | Benzanilide derivative |
WO1994014796A1 (en) * | 1992-12-21 | 1994-07-07 | Yamanouchi Pharmaceutical Co., Ltd. | Novel n-(pyridylcarbonyl)benzazepine derivative and intermediate therefor |
WO1994020473A1 (en) * | 1993-03-11 | 1994-09-15 | Yamanouchi Pharmaceutical Co., Ltd. | Compound with vasopressin antagonism |
GB9307527D0 (en) * | 1993-04-13 | 1993-06-02 | Fujisawa Pharmaceutical Co | New venzamide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
US5516774A (en) * | 1993-07-29 | 1996-05-14 | American Cyanamid Company | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists |
-
1995
- 1995-01-17 US US08/373,125 patent/US5521173A/en not_active Expired - Lifetime
-
1996
- 1996-01-15 AR ARP960101024A patent/AR002021A1/es unknown
- 1996-01-15 ZA ZA96303A patent/ZA96303B/xx unknown
- 1996-01-16 CZ CZ972247A patent/CZ224797A3/cs unknown
- 1996-01-16 MX MX9705414A patent/MX9705414A/es not_active IP Right Cessation
- 1996-01-16 IL IL11677496A patent/IL116774A/xx not_active IP Right Cessation
- 1996-01-16 TW TW085100471A patent/TW472056B/zh not_active IP Right Cessation
- 1996-01-16 JP JP52234496A patent/JP4156664B2/ja not_active Expired - Fee Related
- 1996-01-16 CA CA002210708A patent/CA2210708C/en not_active Expired - Fee Related
- 1996-01-16 AU AU46566/96A patent/AU707881B2/en not_active Ceased
- 1996-01-16 EP EP96902143A patent/EP0805813B1/en not_active Expired - Lifetime
- 1996-01-16 WO PCT/US1996/000515 patent/WO1996022292A1/en not_active Application Discontinuation
- 1996-01-16 CN CN96192570A patent/CN1052725C/zh not_active Expired - Fee Related
- 1996-01-16 NZ NZ301198A patent/NZ301198A/xx unknown
- 1996-01-16 DK DK96902143T patent/DK0805813T3/da active
- 1996-01-16 EA EA199700118A patent/EA000056B1/ru not_active IP Right Cessation
- 1996-01-16 HU HU9702459A patent/HUP9702459A3/hu unknown
- 1996-01-16 BR BR9607177A patent/BR9607177A/pt not_active IP Right Cessation
- 1996-01-16 DE DE69621225T patent/DE69621225T2/de not_active Expired - Fee Related
- 1996-01-16 AT AT96902143T patent/ATE217625T1/de not_active IP Right Cessation
- 1996-01-16 ES ES96902143T patent/ES2175066T3/es not_active Expired - Lifetime
- 1996-01-16 UA UA97084248A patent/UA48960C2/uk unknown
- 1996-01-16 PT PT96902143T patent/PT805813E/pt unknown
- 1996-05-23 US US08/652,198 patent/US5780471A/en not_active Expired - Lifetime
-
1998
- 1998-04-16 HK HK98103196A patent/HK1003891A1/xx not_active IP Right Cessation
-
2007
- 2007-11-21 JP JP2007301897A patent/JP2008069176A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DE69621225T2 (de) | 2002-11-14 |
CN1178532A (zh) | 1998-04-08 |
AR002021A1 (es) | 1998-01-07 |
JP2008069176A (ja) | 2008-03-27 |
NZ301198A (en) | 1999-08-30 |
ES2175066T3 (es) | 2002-11-16 |
ZA96303B (en) | 1997-07-15 |
AU4656696A (en) | 1996-08-07 |
EA199700118A1 (ru) | 1997-12-30 |
CA2210708C (en) | 2005-05-24 |
IL116774A0 (en) | 1996-05-14 |
CZ224797A3 (cs) | 1998-03-18 |
IL116774A (en) | 2000-12-06 |
UA48960C2 (uk) | 2002-09-16 |
JPH11500424A (ja) | 1999-01-12 |
EA000056B1 (ru) | 1998-04-30 |
PT805813E (pt) | 2002-10-31 |
DE69621225D1 (de) | 2002-06-20 |
EP0805813B1 (en) | 2002-05-15 |
WO1996022292A1 (en) | 1996-07-25 |
TW472056B (en) | 2002-01-11 |
CA2210708A1 (en) | 1996-07-25 |
JP4156664B2 (ja) | 2008-09-24 |
DK0805813T3 (da) | 2002-08-05 |
CN1052725C (zh) | 2000-05-24 |
MX9705414A (es) | 1997-11-29 |
EP0805813A1 (en) | 1997-11-12 |
HUP9702459A2 (hu) | 1998-05-28 |
HK1003891A1 (en) | 1998-11-13 |
AU707881B2 (en) | 1999-07-22 |
ATE217625T1 (de) | 2002-06-15 |
US5521173A (en) | 1996-05-28 |
US5780471A (en) | 1998-07-14 |
BR9607177A (pt) | 1997-11-11 |
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