HUP1000565A2 - Process for the preparation of pharmaceutically active compound and intermediers - Google Patents

Process for the preparation of pharmaceutically active compound and intermediers

Info

Publication number
HUP1000565A2
HUP1000565A2 HU1000565A HUP1000565A HUP1000565A2 HU P1000565 A2 HUP1000565 A2 HU P1000565A2 HU 1000565 A HU1000565 A HU 1000565A HU P1000565 A HUP1000565 A HU P1000565A HU P1000565 A2 HUP1000565 A2 HU P1000565A2
Authority
HU
Hungary
Prior art keywords
intermediers
preparation
active compound
pharmaceutically active
pharmaceutically
Prior art date
Application number
HU1000565A
Other languages
English (en)
Inventor
Balint Nyulasi
Marta Porcs-Makkay
Gabor Dr Numeth
Tamas Dr Gregor
Jozsef Dr Barkoczy
Balazs Volk
Kalman Dr Nagy
Gyorgy Ruzsics
Zsofia Papp-Fuezfai
Enik Molnar
Angula Pandur
Adrienn Keszthelyi
Tibor Dr Mezei
David Frigyes
Original Assignee
Egis Gyogyszergyar Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyogyszergyar Nyrt filed Critical Egis Gyogyszergyar Nyrt
Priority to HU1000565A priority Critical patent/HUP1000565A2/hu
Publication of HU1000565D0 publication Critical patent/HU1000565D0/hu
Priority to PCT/HU2011/000099 priority patent/WO2012052788A1/en
Publication of HUP1000565A2 publication Critical patent/HUP1000565A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
HU1000565A 2010-10-22 2010-10-22 Process for the preparation of pharmaceutically active compound and intermediers HUP1000565A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU1000565A HUP1000565A2 (en) 2010-10-22 2010-10-22 Process for the preparation of pharmaceutically active compound and intermediers
PCT/HU2011/000099 WO2012052788A1 (en) 2010-10-22 2011-10-21 Method for preparing pharmaceutically active ingredient and intermediates thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU1000565A HUP1000565A2 (en) 2010-10-22 2010-10-22 Process for the preparation of pharmaceutically active compound and intermediers

Publications (2)

Publication Number Publication Date
HU1000565D0 HU1000565D0 (en) 2010-12-28
HUP1000565A2 true HUP1000565A2 (en) 2012-05-02

Family

ID=89990017

Family Applications (1)

Application Number Title Priority Date Filing Date
HU1000565A HUP1000565A2 (en) 2010-10-22 2010-10-22 Process for the preparation of pharmaceutically active compound and intermediers

Country Status (2)

Country Link
HU (1) HUP1000565A2 (hu)
WO (1) WO2012052788A1 (hu)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014114964A2 (en) 2013-01-24 2014-07-31 Egis Pharmaceuticals Public Limited Company Improved process for the preparation of prasugrel and intermediate thereof

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU231079B1 (hu) 2016-06-23 2020-06-29 Richter Gedeon Nyrt. Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával
CN112047959A (zh) * 2020-10-21 2020-12-08 深圳市祥根生物科技有限公司 一种普拉格雷开环氯代杂质的制备方法
CN114216990B (zh) * 2021-12-24 2023-04-07 珠海润都制药股份有限公司 一种溴代三苯甲基四氮唑联苯中二溴海因的检测方法
CN116183772B (zh) * 2023-03-03 2023-09-15 华夏生生药业(北京)有限公司 一种原料药中致突变杂质检测方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101150B (fi) 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
EP0785205B1 (en) 1994-10-07 2002-04-17 Ube Industries, Ltd. 2-silyloxytetrahydrothienopyridine, salt thereof, and process for producing the same
CA2415558C (en) 2000-07-06 2010-09-14 Sankyo Company, Limited Acid addition salts of hydropyridine derivatives
WO2007115305A2 (en) 2006-04-04 2007-10-11 Cogentus Pharmaceuticals, Inc. Oral dosage forms including an antiplatelet agent and an acid inhibitor
TWI392681B (zh) 2006-04-06 2013-04-11 Daiichi Sankyo Co Ltd 高純度普拉格雷及其酸加成鹽之製法
NZ579993A (en) 2007-03-02 2012-06-29 Daiichi Sankyo Co Ltd Process for production of prasugrel hydrochloride having high purity
CZ302135B6 (cs) 2007-07-09 2010-11-10 Zentiva, A. S. Zpusob výroby 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4, 5, 6, 7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu (prasugrelu)
US20100261908A1 (en) 2007-11-09 2010-10-14 Dr. Reddy's Laboratories Ltd. Processes for the preparation of prasugrel , and its salts and polymorphs
WO2009066326A2 (en) 2007-11-19 2009-05-28 Msn Laboratories Limited Improved process for the preparation of prasugrel and its pharmaceutically acceptable salts
HU230261B1 (hu) 2007-11-27 2015-11-30 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Eljárás gyógyszeripari intermedierek előállítására
CN101245072B (zh) 2008-03-21 2011-03-30 上海医药工业研究院 制备普拉格雷的中间体及其制备方法
CN101245073B (zh) 2008-03-21 2011-03-23 上海医药工业研究院 一种医药中间体及其制备方法
CN101250192B (zh) 2008-03-24 2010-08-11 上海医药工业研究院 5-(α-环丙基羰基-2-氟苄基)-2-氧-2,4,5,6,7,7a-六氢噻吩并[3,2-c]吡啶的制备方法
CN101250193B (zh) 2008-03-28 2010-09-08 上海医药工业研究院 2-烷氧基-5-(α-环丙基羰基-2-氟苄基)-4,5,6,7-四氢噻吩并[3,2-c]吡啶的制备方法
WO2009122440A1 (en) 2008-03-31 2009-10-08 Torrent Pharmaceuticals Ltd. PROCESS FOR THE PREPARATION OF 2-ACETOXY-5-(α -CYCLOPRPYLCARBONYL -2-FLUOROBENZYL)-4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE
CN101531667A (zh) 2009-04-16 2009-09-16 上海立科药物化学有限公司 普拉格雷中间体的合成方法及合成普拉格雷的方法
CN102101827B (zh) * 2010-11-15 2013-07-03 山东新华制药股份有限公司 一种普拉格雷中间体α-环丙羰基-2-氟苄基卤的制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014114964A2 (en) 2013-01-24 2014-07-31 Egis Pharmaceuticals Public Limited Company Improved process for the preparation of prasugrel and intermediate thereof

Also Published As

Publication number Publication date
WO2012052788A1 (en) 2012-04-26
HU1000565D0 (en) 2010-12-28

Similar Documents

Publication Publication Date Title
IL238337A (en) A process for preparing pharmaceutical active compounds
ZA201306237B (en) Solid forms of a pharmaceutically active substance
IL224544B (en) Compound useful for the treatment of nonsense-mutation-mediated diseases and pharmaceutical composition comprising said compound
PL2632889T3 (pl) Związki pośrednie i sposób wytwarzania fingolimodu
ZA201207397B (en) Process for the preparation of dexlansoprazole
SI2736909T1 (sl) Proces za pripravo sitagliptina in njegovih farmacevtsko sprejemljivih soli
HUP1000565A2 (en) Process for the preparation of pharmaceutically active compound and intermediers
EP2596007A4 (en) PROCESS FOR THE PREPARATION OF 17-DEOXY-CORTICOSTEROIDS
ZA201300546B (en) Process for the preparation of 3-haloalkylpyrazoles
PT2593423E (pt) Processo para a preparação de agentes de contraste
PT2603319E (pt) Processo para a preparação de uretanos
HUP1000444A2 (en) Process for the preparation of a pharmaceutical active ingredient
GB201001203D0 (en) Use of pharmaceutically active compounds
PT2390246T (pt) Processo para a preparação de aminaftona
PL2607354T3 (pl) Nowy sposób syntezy iwabradyny i jej soli addycyjnych z kwasem farmaceutycznie dopuszczalnym
GB201301307D0 (en) Crystalline form of prulifloxacin and processes for its preparation
PL2598504T3 (pl) Sposób otrzymywania dimiracetamu
PL391702A1 (pl) Sposób otrzymywania 5-hydroksykreatyniny i N-metyloguanidyny
ZA201303371B (en) Crystalline pharmaceutically active ingredients
RS20100352A3 (en) METHOD OF PREPARATION AND USE OF PHARMACOLOGICAL ACTIVE N-CARBAMYLMETHYL-4 (R) -Phenyl-2-Pyrrolidinone
PL391303A1 (pl) Nowa pochodna pirymidopirymidyny i sposób wytwarzania nowej pochodnej pirymidopirymidyny
PL391316A1 (pl) Nowa pochodna pirymidopirymidyny i sposób wytwarzania nowej pochodnej pirymidopirymidyny
IL226042A (en) Intermediates and methods for making pingolimod
PL391137A1 (pl) Sposób wytwarzania aktywnych nanowłókien węglowych o zwiększonej powierzchni właściwej
IL224304A (en) A process for making dichlorobulben

Legal Events

Date Code Title Description
FC4A Lapse of provisional application due to refusal