HUP0900482A2 - Pharmaceutical formulation for oral administration - Google Patents

Pharmaceutical formulation for oral administration

Info

Publication number
HUP0900482A2
HUP0900482A2 HU0900482A HUP0900482A HUP0900482A2 HU P0900482 A2 HUP0900482 A2 HU P0900482A2 HU 0900482 A HU0900482 A HU 0900482A HU P0900482 A HUP0900482 A HU P0900482A HU P0900482 A2 HUP0900482 A2 HU P0900482A2
Authority
HU
Hungary
Prior art keywords
oral administration
pharmaceutical formulation
formulation
pharmaceutical
oral
Prior art date
Application number
HU0900482A
Other languages
English (en)
Inventor
Zoltan Dr Szilvassy
Barna Dr Peitl
Jozsef Dr Nemeth
Original Assignee
Cera Med Kft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cera Med Kft filed Critical Cera Med Kft
Priority to HU0900482A priority Critical patent/HUP0900482A2/hu
Publication of HU0900482D0 publication Critical patent/HU0900482D0/hu
Priority to JP2012523416A priority patent/JP2013501043A/ja
Priority to US13/387,212 priority patent/US20120129769A1/en
Priority to EP10757272A priority patent/EP2461820A1/en
Priority to PCT/IB2010/053499 priority patent/WO2011015984A1/en
Priority to CA2769620A priority patent/CA2769620A1/en
Priority to UAA201202346A priority patent/UA106506C2/uk
Priority to KR1020127005524A priority patent/KR20120088660A/ko
Priority to CN201080038764XA priority patent/CN102791282A/zh
Priority to AU2010280418A priority patent/AU2010280418B2/en
Priority to BR112012002413A priority patent/BR112012002413A2/pt
Priority to RU2012109006/15A priority patent/RU2012109006A/ru
Priority to MX2012001461A priority patent/MX2012001461A/es
Publication of HUP0900482A2 publication Critical patent/HUP0900482A2/hu
Priority to IL217856A priority patent/IL217856A0/en
Priority to ZA2012/01519A priority patent/ZA201201519B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
HU0900482A 2009-08-03 2009-08-03 Pharmaceutical formulation for oral administration HUP0900482A2 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
HU0900482A HUP0900482A2 (en) 2009-08-03 2009-08-03 Pharmaceutical formulation for oral administration
MX2012001461A MX2012001461A (es) 2009-08-03 2010-08-02 Preparacion farmaceutica, de administracion oral, que contiene insulina.
UAA201202346A UA106506C2 (uk) 2009-08-03 2010-08-02 Інсулінвмісний фармацевтичний препарат для перорального застосування
CN201080038764XA CN102791282A (zh) 2009-08-03 2010-08-02 可口服给予的含有胰岛素的药物制剂
EP10757272A EP2461820A1 (en) 2009-08-03 2010-08-02 Orally administerable pharmaceutical preparation containing insulin
PCT/IB2010/053499 WO2011015984A1 (en) 2009-08-03 2010-08-02 Orally administerable pharmaceutical preparation containing insulin
CA2769620A CA2769620A1 (en) 2009-08-03 2010-08-02 Orally administerable pharmaceutical preparation containing insulin
JP2012523416A JP2013501043A (ja) 2009-08-03 2010-08-02 経口投与可能な医薬製剤
KR1020127005524A KR20120088660A (ko) 2009-08-03 2010-08-02 경구투여가능한 인슐린 함유 약제학적 조성물
US13/387,212 US20120129769A1 (en) 2009-08-03 2010-08-02 Orally administerable pharmaceutical preparation containing insulin
AU2010280418A AU2010280418B2 (en) 2009-08-03 2010-08-02 Orally administerable pharmaceutical preparation containing insulin
BR112012002413A BR112012002413A2 (pt) 2009-08-03 2010-08-02 preparação farmacêutica administrável oralmente contendo insulina
RU2012109006/15A RU2012109006A (ru) 2009-08-03 2010-08-02 Инсулинсодержащий фармацевтический препарат для перорального применения
IL217856A IL217856A0 (en) 2009-08-03 2012-01-31 Orally administerable pharmaceutical preparation containing insulin
ZA2012/01519A ZA201201519B (en) 2009-08-03 2012-02-29 Orally administerable pharmaceutical preparation containing insulin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0900482A HUP0900482A2 (en) 2009-08-03 2009-08-03 Pharmaceutical formulation for oral administration

Publications (2)

Publication Number Publication Date
HU0900482D0 HU0900482D0 (en) 2009-10-28
HUP0900482A2 true HUP0900482A2 (en) 2011-03-28

Family

ID=89989155

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0900482A HUP0900482A2 (en) 2009-08-03 2009-08-03 Pharmaceutical formulation for oral administration

Country Status (15)

Country Link
US (1) US20120129769A1 (hu)
EP (1) EP2461820A1 (hu)
JP (1) JP2013501043A (hu)
KR (1) KR20120088660A (hu)
CN (1) CN102791282A (hu)
AU (1) AU2010280418B2 (hu)
BR (1) BR112012002413A2 (hu)
CA (1) CA2769620A1 (hu)
HU (1) HUP0900482A2 (hu)
IL (1) IL217856A0 (hu)
MX (1) MX2012001461A (hu)
RU (1) RU2012109006A (hu)
UA (1) UA106506C2 (hu)
WO (1) WO2011015984A1 (hu)
ZA (1) ZA201201519B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2726091T3 (pl) * 2011-06-29 2020-08-10 Rani Therapeutics, Llc Preparaty lecznicze dostarczane do kanału przewodu jelitowego za pomocą połykalnego urządzenia dostarczającego lek
US20200126671A1 (en) * 2017-06-28 2020-04-23 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Method for determining the risk to develop type 1 diabetes

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3172814A (en) 1962-04-06 1965-03-09 Jr Edgar A Ferguson Oral blood sugar lowering compositions
JPS5428807A (en) 1977-08-09 1979-03-03 Hiroyuki Sumi Oral insulin
IL68769A (en) * 1983-05-23 1986-02-28 Hadassah Med Org Pharmaceutical compositions containing insulin for oral administration
ES2045276T3 (es) 1988-07-21 1994-01-16 Hoffmann La Roche Preparacion de insulina
CA2125284C (en) 1991-12-05 2000-06-20 Jens-Christian Wunderlich Peroral administration form for peptidic medicaments, in particular insulin
JP3047948B2 (ja) * 1992-12-07 2000-06-05 株式会社ツムラ ペプチド類経鼻投与用組成物
US5359030A (en) 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
US5968899A (en) * 1994-06-03 1999-10-19 Tsumura & Co. Medicinal compositions of peptides with EACA or tranexamic acid for enhanced mucosal absorption
US5461031A (en) * 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
US5653987A (en) 1995-05-16 1997-08-05 Modi; Pankaj Liquid formulations for proteinic pharmaceuticals
US5970193A (en) 1996-10-24 1999-10-19 Nortel Networks Corporation Data communications structures relating to data shelf configurations
NZ500075A (en) 1997-04-02 2001-03-30 Purdue Research Foundation Method for the oral delivery of a protein encapsulated within a hydrogel matrix
CN1329502A (zh) 1998-12-04 2002-01-02 普罗瓦利斯英国有限公司 含有胰岛素的药物组合物
US6375975B1 (en) 1998-12-21 2002-04-23 Generex Pharmaceuticals Incorporated Pharmaceutical compositions for buccal and pulmonary application
PT1454630E (pt) 2003-03-04 2010-12-15 Technology Dev Company Ltd Composição de insulina injectável de acção prolongada e métodos para o seu fabrico e utilização
JP5103748B2 (ja) * 2005-02-16 2012-12-19 東レ株式会社 医薬組成物
EP2722054B1 (en) * 2005-09-06 2018-03-21 Oramed Pharmaceuticals Inc. Methods and compositions for oral administration of proteins
US8927015B2 (en) 2006-04-12 2015-01-06 Emisphere Technologies, Inc. Formulations for delivering insulin
CN101062408B (zh) * 2006-04-27 2010-12-08 深圳市隆阳生物科技有限公司 口服胰岛素复合制剂及其制备方法
JP2008266179A (ja) * 2007-04-19 2008-11-06 Fujifilm Corp 経肺用組成物
EP2164466A1 (en) * 2007-06-01 2010-03-24 Novo Nordisk A/S Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier
NZ591497A (en) * 2008-08-18 2012-11-30 Entera Bio Ltd A compositions comprising a protein, a protease inhibitor and N-(8-[2-hydroxybenzoyl]amino)caprylate (SNAC) or N-(10[2-hydroxybenzoyl]amino)decanoate (SNAD) for diabetes mellitus treatment

Also Published As

Publication number Publication date
KR20120088660A (ko) 2012-08-08
AU2010280418A1 (en) 2012-03-22
RU2012109006A (ru) 2013-09-10
UA106506C2 (uk) 2014-09-10
AU2010280418B2 (en) 2015-04-09
EP2461820A1 (en) 2012-06-13
JP2013501043A (ja) 2013-01-10
ZA201201519B (en) 2013-05-29
MX2012001461A (es) 2012-05-22
IL217856A0 (en) 2012-03-29
US20120129769A1 (en) 2012-05-24
WO2011015984A1 (en) 2011-02-10
CA2769620A1 (en) 2011-02-10
BR112012002413A2 (pt) 2016-03-01
CN102791282A (zh) 2012-11-21
HU0900482D0 (en) 2009-10-28

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Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished