HUP0400386A2 - Cetirizint és pszeudoefedrint tartalmazó tabletta és alkalmazása gyógyszerkészítmények előállítására - Google Patents
Cetirizint és pszeudoefedrint tartalmazó tabletta és alkalmazása gyógyszerkészítmények előállításáraInfo
- Publication number
- HUP0400386A2 HUP0400386A2 HU0400386A HUP0400386A HUP0400386A2 HU P0400386 A2 HUP0400386 A2 HU P0400386A2 HU 0400386 A HU0400386 A HU 0400386A HU P0400386 A HUP0400386 A HU P0400386A HU P0400386 A2 HUP0400386 A2 HU P0400386A2
- Authority
- HU
- Hungary
- Prior art keywords
- tablet
- cetirizine
- pseudoephedrine
- preparation
- pharmaceutical compositions
- Prior art date
Links
- ZKLPARSLTMPFCP-UHFFFAOYSA-N Cetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001803 cetirizine Drugs 0.000 title abstract 3
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 title abstract 3
- KWGRBVOPPLSCSI-WCBMZHEXSA-N pseudoephedrine Chemical compound CN[C@@H](C)[C@@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WCBMZHEXSA-N 0.000 title abstract 3
- 229960003908 pseudoephedrine Drugs 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 2
- 230000003113 alkalizing effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A találmány tárgya tabletta, amely legalább két elkülönített szegmensttartalmaz, az egyik szegmensben a hatóanyag túlnyomó részt cetirizin,a második szegmens hatóanyag túlnyomó részt pszeudoefedrin és aszegmensek úgy vannak kialakítva, hogy a kapott tabletta lényegébenmentes a cetirizin és pszeudoefedrin közötti reakcióból származószennyeződésektől, továbbá azzal a megkötéssel, hogy a tablettaössztömegére számítva kevesebb mint 5 tömeg% lúgosítószert tartalmaz.A találmány vonatkozik továbbá a találmány szerinti tablettaalkalmazására többek között nátha, megfázás, influenza, influenzaszerűés náthaszerű betegségek és ennek tüneteinek kezelésére szolgálógyógyszerkészítmények előállítására is. Ó
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30125001P | 2001-06-28 | 2001-06-28 | |
| EP01115807 | 2001-06-28 | ||
| PCT/EP2002/006342 WO2003002098A1 (en) | 2001-06-28 | 2002-06-10 | Tablet comprising cetirizine and pseudoephedrine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HUP0400386A2 true HUP0400386A2 (hu) | 2004-08-30 |
| HUP0400386A3 HUP0400386A3 (en) | 2006-02-28 |
| HU229803B1 HU229803B1 (en) | 2014-07-28 |
Family
ID=56290291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0400386A HU229803B1 (en) | 2001-06-28 | 2002-06-10 | Tablet comprising cetirizine and pseudoephedrine |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1404304B1 (hu) |
| JP (1) | JP4041460B2 (hu) |
| KR (1) | KR100926410B1 (hu) |
| CN (1) | CN100490809C (hu) |
| AT (1) | ATE432068T1 (hu) |
| AU (1) | AU2002345024B2 (hu) |
| BR (1) | BR0210650A (hu) |
| CA (1) | CA2451519C (hu) |
| CZ (1) | CZ20033454A3 (hu) |
| DK (1) | DK1404304T3 (hu) |
| EE (1) | EE05357B1 (hu) |
| ES (1) | ES2324769T3 (hu) |
| HU (1) | HU229803B1 (hu) |
| MX (1) | MXPA03010430A (hu) |
| NZ (1) | NZ530289A (hu) |
| PL (1) | PL206069B1 (hu) |
| PT (1) | PT1404304E (hu) |
| RO (1) | RO122476B1 (hu) |
| RU (1) | RU2286784C2 (hu) |
| SI (1) | SI1404304T1 (hu) |
| SK (1) | SK287645B6 (hu) |
| WO (1) | WO2003002098A1 (hu) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL159287A0 (en) * | 2001-06-28 | 2004-06-01 | Ucb Farchim Sa | Tablet comprising cetirizine and pseudoephedrine |
| KR100698400B1 (ko) | 2004-04-14 | 2007-03-23 | 이은주 | 탈모증 및 전립선비대증 치료를 위한 약제학적 조성물 |
| WO2007141743A2 (en) * | 2006-06-06 | 2007-12-13 | Ranbaxy Laboratories Limited | A tablet dosage form comprising cetirizine and pseudoephedrine |
| PT2099442E (pt) | 2006-12-26 | 2015-02-10 | Pharmacyclics Inc | Métodos de utilização de inibidores de histona desacetilase e monitorização de biomarcadores em terapia de combinação |
| US8439033B2 (en) | 2007-10-09 | 2013-05-14 | Microdose Therapeutx, Inc. | Inhalation device |
| CN104338219B (zh) | 2010-01-05 | 2017-10-24 | 微剂量治疗技术公司 | 吸入设备和方法 |
| KR101193495B1 (ko) | 2010-02-01 | 2012-10-23 | 한미사이언스 주식회사 | 슈도에페드린 및 레보세티리진을 포함하는 경구용 복합 조성물 |
| EP2582373A4 (en) | 2010-06-16 | 2013-10-30 | Bruce Chandler May | USE OF LEVOCETIRIZIN AND MONTELUKAST IN THE TREATMENT OF INFLUENZA, COLLECTIONS AND INFLAMMATION |
| CN102302497A (zh) * | 2011-05-18 | 2012-01-04 | 天圣制药集团股份有限公司 | 一种治疗过敏性鼻炎的制剂及其制备方法 |
| KR20130009553A (ko) | 2011-07-15 | 2013-01-23 | 한미약품 주식회사 | 몬테루카스트 또는 이의 약학적으로 허용가능한 염 및 레보세티리진 또는 이의 약학적으로 허용가능한 염을 함유하는 캡슐 제제 |
| MX365393B (es) | 2011-09-13 | 2019-05-31 | Pharmacyclics Llc | Formulaciones de inhibidor de histona deacetilasa en combinación con bendamustina y usos de las mismas. |
| KR101372324B1 (ko) * | 2012-02-09 | 2014-03-13 | 동국대학교 경주캠퍼스 산학협력단 | 알러지성 비염 치료를 위한 한방 치료제 및 슈도에페드린을 함유한 복합서방형의 약제학적 조성물 |
| ES2770760T3 (es) | 2013-03-13 | 2020-07-03 | Inflammatory Response Res Inc | Uso de levocetirizina y montelukast en el tratamiento de lesiones traumáticas |
| CA2901413A1 (en) | 2013-03-13 | 2014-10-09 | Bruce Chandler May | Use of levocetirizine and montelukast in the treatment of vasculitis |
| EP3300734B1 (en) | 2013-03-13 | 2019-08-14 | Inflammatory Response Research, Inc. | Use of levocetirizine and montelukast in the treatment of autoimmune disorders |
| WO2016044095A1 (en) | 2014-09-15 | 2016-03-24 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| WO2016140630A1 (en) | 2015-03-05 | 2016-09-09 | PHARMACTIVE ILAÇ SANAYI VE TlCARET A. Ş. | An effervescent composition comprising levocetirizine and pseudoephedrine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0811374A1 (en) * | 1996-05-29 | 1997-12-10 | Pfizer Inc. | Combination dosage form comprising cetirizine and pseudoephedrine |
| BE1011045A3 (fr) * | 1997-03-14 | 1999-04-06 | Ucb Sa | Compositions pharmaceutiques pour la liberation controlee de substances actives. |
| US6267986B1 (en) * | 1999-09-24 | 2001-07-31 | Ranbaxy Laboratories Limited | Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine |
-
2002
- 2002-06-10 EE EEP200400005A patent/EE05357B1/xx unknown
- 2002-06-10 KR KR1020037017054A patent/KR100926410B1/ko active IP Right Grant
- 2002-06-10 RO ROA200301062A patent/RO122476B1/ro unknown
- 2002-06-10 HU HU0400386A patent/HU229803B1/hu unknown
- 2002-06-10 AT AT02743173T patent/ATE432068T1/de active
- 2002-06-10 MX MXPA03010430A patent/MXPA03010430A/es active IP Right Grant
- 2002-06-10 PT PT02743173T patent/PT1404304E/pt unknown
- 2002-06-10 WO PCT/EP2002/006342 patent/WO2003002098A1/en active Application Filing
- 2002-06-10 SK SK1550-2003A patent/SK287645B6/sk not_active IP Right Cessation
- 2002-06-10 SI SI200230844T patent/SI1404304T1/sl unknown
- 2002-06-10 NZ NZ530289A patent/NZ530289A/en unknown
- 2002-06-10 ES ES02743173T patent/ES2324769T3/es not_active Expired - Lifetime
- 2002-06-10 JP JP2003508337A patent/JP4041460B2/ja not_active Expired - Fee Related
- 2002-06-10 AU AU2002345024A patent/AU2002345024B2/en not_active Ceased
- 2002-06-10 BR BR0210650-7A patent/BR0210650A/pt not_active Application Discontinuation
- 2002-06-10 RU RU2004101231/15A patent/RU2286784C2/ru active
- 2002-06-10 PL PL366800A patent/PL206069B1/pl unknown
- 2002-06-10 EP EP02743173A patent/EP1404304B1/en not_active Expired - Lifetime
- 2002-06-10 CZ CZ20033454A patent/CZ20033454A3/cs unknown
- 2002-06-10 CN CNB02812975XA patent/CN100490809C/zh not_active Expired - Lifetime
- 2002-06-10 CA CA002451519A patent/CA2451519C/en not_active Expired - Lifetime
- 2002-06-10 DK DK02743173T patent/DK1404304T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004536829A (ja) | 2004-12-09 |
| EP1404304B1 (en) | 2009-05-27 |
| CA2451519A1 (en) | 2003-01-09 |
| SI1404304T1 (sl) | 2009-10-31 |
| MXPA03010430A (es) | 2004-12-06 |
| PT1404304E (pt) | 2009-06-26 |
| CN100490809C (zh) | 2009-05-27 |
| HUP0400386A3 (en) | 2006-02-28 |
| KR100926410B1 (ko) | 2009-11-12 |
| DK1404304T3 (da) | 2009-07-13 |
| HU229803B1 (en) | 2014-07-28 |
| ATE432068T1 (de) | 2009-06-15 |
| WO2003002098A1 (en) | 2003-01-09 |
| PL366800A1 (en) | 2005-02-07 |
| PL206069B1 (pl) | 2010-06-30 |
| SK15502003A3 (sk) | 2004-05-04 |
| RO122476B1 (ro) | 2009-07-30 |
| EP1404304A1 (en) | 2004-04-07 |
| CA2451519C (en) | 2007-11-06 |
| RU2286784C2 (ru) | 2006-11-10 |
| CZ20033454A3 (cs) | 2004-08-18 |
| NZ530289A (en) | 2004-11-26 |
| JP4041460B2 (ja) | 2008-01-30 |
| KR20040007756A (ko) | 2004-01-24 |
| ES2324769T3 (es) | 2009-08-14 |
| EE200400005A (et) | 2004-02-16 |
| SK287645B6 (sk) | 2011-05-06 |
| EE05357B1 (et) | 2010-12-15 |
| RU2004101231A (ru) | 2005-04-20 |
| CN1520285A (zh) | 2004-08-11 |
| BR0210650A (pt) | 2004-10-05 |
| AU2002345024B2 (en) | 2006-09-07 |
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