HUP0302481A2 - Virulencia gének, fehérjék és alkalmazásuk - Google Patents

Virulencia gének, fehérjék és alkalmazásuk

Info

Publication number
HUP0302481A2
HUP0302481A2 HU0302481A HUP0302481A HUP0302481A2 HU P0302481 A2 HUP0302481 A2 HU P0302481A2 HU 0302481 A HU0302481 A HU 0302481A HU P0302481 A HUP0302481 A HU P0302481A HU P0302481 A2 HUP0302481 A2 HU P0302481A2
Authority
HU
Hungary
Prior art keywords
peptides
proteins
virulence genes
nucleotide sequences
relates
Prior art date
Application number
HU0302481A
Other languages
English (en)
Inventor
Christoph Tang
Original Assignee
Microscience Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microscience Limited filed Critical Microscience Limited
Publication of HUP0302481A2 publication Critical patent/HUP0302481A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/36—Neisseria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A találmány olyan génekre és fehérjékre/peptidekre vonatkozik, amelyeka Neisseria meningitidisből származnak. A találmány tárgyát képeziktovábbá a peptideket kifejező gazdasejtek, valamint a peptideketkódoló nukleotidszekvenciákban mutációt hordozó gyengítettmikroorganizmusok. A találmány a fenti nukleotidszekvenciák, peptidekés mikroorganizmusok terápiás alkalmazásra és gyógyszerkészítményekszkrínelésére való felhasználására is vonatkozik. Ó
HU0302481A 2000-05-08 2001-05-08 Virulencia gének, fehérjék és alkalmazásuk HUP0302481A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0011108.8A GB0011108D0 (en) 2000-05-08 2000-05-08 Virulence gene and protein and their use
PCT/GB2001/002003 WO2001085772A2 (en) 2000-05-08 2001-05-08 Virulence genes, proteins, and their use

Publications (1)

Publication Number Publication Date
HUP0302481A2 true HUP0302481A2 (hu) 2003-10-28

Family

ID=9891203

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302481A HUP0302481A2 (hu) 2000-05-08 2001-05-08 Virulencia gének, fehérjék és alkalmazásuk

Country Status (16)

Country Link
US (2) US20040087770A1 (hu)
EP (2) EP1287024B1 (hu)
JP (1) JP2003532404A (hu)
KR (3) KR20030032948A (hu)
CN (2) CN1427892A (hu)
AT (1) ATE382056T1 (hu)
AU (1) AU776508B2 (hu)
CA (1) CA2408738A1 (hu)
CZ (1) CZ20023642A3 (hu)
DE (1) DE60132084T2 (hu)
GB (1) GB0011108D0 (hu)
HU (1) HUP0302481A2 (hu)
NO (1) NO20025329L (hu)
NZ (3) NZ522277A (hu)
RU (2) RU2252224C2 (hu)
WO (1) WO2001085772A2 (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ502020A (en) 1994-12-09 2001-06-29 Imp College Innovations Ltd Identification of virulence gene cluster from Salmonella typhimurium called virulence gene cluster 2 ( VGC2 )
DK1108034T3 (da) 1998-09-04 2008-11-10 Emergent Product Dev Uk Ltd Svækkede salmonella SPI2-mutanter som antigenbærere
EP2270169A3 (en) 1999-03-12 2011-06-15 GlaxoSmithKline Biologicals SA Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies
GB9910812D0 (en) 1999-05-10 1999-07-07 Microscience Ltd Vaccine composition
US20060240045A1 (en) * 2002-08-02 2006-10-26 Francois-Xavier Berthet Neisserial vaccine compositions comprising a combination of antigens
GB0330007D0 (en) * 2003-12-23 2004-01-28 Imp College Innovations Ltd Vaccines
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
ATE548051T1 (de) 2005-04-08 2012-03-15 Wyeth Llc Multivalente pneumokokken- polysaccharidproteinkonjugatzusammensetzung
EP2215074B1 (en) * 2007-09-27 2014-02-19 The United States of America, as Represented by the Secretary, Department of Health and Human Services Isoindoline compounds for the treatment of spinal muscular atrophy and other uses
WO2009158240A1 (en) 2008-06-16 2009-12-30 Emergent Product Development Uk Limited Salmonella vectored vaccines against chlamydia and methods of use
GB0816447D0 (en) * 2008-09-08 2008-10-15 Glaxosmithkline Biolog Sa Vaccine
ES2663872T3 (es) * 2010-03-11 2018-04-17 Glaxosmithkline Biologicals S.A. Composición inmunogénica o vacuna contra infección o enfermedad bacteriana gramnegativa, por ejemplo, por Neisseria
CN111118043B (zh) * 2020-01-13 2022-07-05 吉林大学 一种苦豆子SaMET6基因克隆及其应用
CN116042562B (zh) * 2022-03-11 2023-10-20 山东恒鲁生物科技有限公司 重组酵母菌及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2047043A1 (en) * 1990-07-19 1992-01-20 Allen I. Oliff Class ii protein of the outer membrane of neisseria meningitidis having immune enhancement properties
US5338664A (en) * 1992-12-04 1994-08-16 American Cyanamid Company Assay for detection of bacterial iron transport inhibitors
US6121037A (en) * 1994-10-18 2000-09-19 Stojiljkovic; Igor Bacterial hemoglobin receptor genes
NZ502020A (en) * 1994-12-09 2001-06-29 Imp College Innovations Ltd Identification of virulence gene cluster from Salmonella typhimurium called virulence gene cluster 2 ( VGC2 )
FR2751000B1 (fr) * 1996-07-12 1998-10-30 Inst Nat Sante Rech Med Adn specifiques des bacteries de l'espece neisseria meningitidis, leurs procedes d'obtention et leurs applications biologiques
US6472518B1 (en) * 1996-10-24 2002-10-29 Centers For Disease Control And Prevention, As Represented By The Secretary, Department Of Health And Human Services Invasion associated genes from Neisseria meningitidis serogroup B
GB9711964D0 (en) * 1997-06-09 1997-08-06 Medical Res Council Live attenuated vaccines
EP1003874B1 (en) * 1997-08-15 2006-11-02 Rijksuniversiteit Utrecht Neisseria lactoferrin binding protein
WO1999024578A2 (en) * 1997-11-06 1999-05-20 Chiron S.P.A. Neisserial antigens
EP1073748A2 (en) * 1998-04-29 2001-02-07 American Cyanamid Company Vaccines containing recombinant pilin against neisseria gonorrhoeae or neisseria meningitidis
GB9811260D0 (en) * 1998-05-26 1998-07-22 Smithkline Beecham Biolog Novel compounds
WO2000022430A2 (en) * 1998-10-09 2000-04-20 Chiron Corporation Neisseria genomic sequences and methods of their use
US6610836B1 (en) * 1999-01-29 2003-08-26 Genome Therapeutics Corporation Nucleic acid amino acid sequences relating to Klebsiella pneumoniae for diagnostics and therapeutics
ATE430207T1 (de) * 1999-04-30 2009-05-15 Novartis Vaccines & Diagnostic Genomische sequenzen von neisseria und verfahren zu ihrer verwendung

Also Published As

Publication number Publication date
EP1908839A3 (en) 2008-07-16
KR20030032948A (ko) 2003-04-26
DE60132084T2 (de) 2008-12-11
ATE382056T1 (de) 2008-01-15
CZ20023642A3 (cs) 2003-04-16
NZ522277A (en) 2004-05-28
AU776508B2 (en) 2004-09-09
NO20025329L (no) 2003-01-06
RU2252224C2 (ru) 2005-05-20
CA2408738A1 (en) 2001-11-15
CN1427892A (zh) 2003-07-02
NZ532297A (en) 2005-07-29
EP1908839A2 (en) 2008-04-09
GB0011108D0 (en) 2000-06-28
WO2001085772A2 (en) 2001-11-15
KR20070102447A (ko) 2007-10-18
US20080241151A1 (en) 2008-10-02
EP1287024A2 (en) 2003-03-05
DE60132084D1 (de) 2008-02-07
AU5242201A (en) 2001-11-20
WO2001085772A3 (en) 2002-03-28
KR20080080069A (ko) 2008-09-02
RU2005101623A (ru) 2006-07-10
EP1287024B1 (en) 2007-12-26
US20040087770A1 (en) 2004-05-06
NZ549068A (en) 2008-03-28
CN1840665A (zh) 2006-10-04
JP2003532404A (ja) 2003-11-05
NO20025329D0 (no) 2002-11-06

Similar Documents

Publication Publication Date Title
HUP0203409A2 (hu) Gamma-interferon-konjugátumok
HUP0302481A2 (hu) Virulencia gének, fehérjék és alkalmazásuk
HUP0101734A2 (hu) Béta-amiloid prekurzor protein és ubiquitin-B kereteltolódásos mutánsok és alkalmazásuk
Hwang et al. Kinetic and mutational dissection of the two ATPase activities of terminase, the DNA packaging enzyme of bacteriophage λ
HUP0202882A2 (en) Novel b7-4 molecules and uses therefor
DE69738581D1 (de) Menschliche dnase i hyperaktive varianten
HUP0300814A2 (hu) Peptidszelekciós módszer
HUP0302965A2 (hu) Vakcina
HUP0302585A2 (hu) Egy egyén allergiás reakcióra való hajlamának csökkentésére képes tejsavbaktériumok
NZ515936A (en) Antigenic Neisserial peptides
HUP0102302A2 (hu) Heliomicint kódoló gén és alkalmazása
DE60203692D1 (de) Latency associated peptide von tgf-beta um pharmazeutisch aktive proteine latent zu machen
NO20052216L (no) Smertestillende midler
IL138615A0 (en) Alphaviral gene expression system and dna molecules for use therein
EP1100815A4 (en) PROTEASE TYPE II CLEAVABLE PEPTIDE
DE69736276D1 (de) Menschliche dnase resistent gegen actininhibitoren
HUP0100267A2 (hu) Helicobacter pylori eredetű nukleinsav- és aminosav-szekvenciák és a megfelelő nukleinsavakat vagy peptideket tartalmazó vakcina-készítmények
HUP0300813A2 (hu) Gének, fehérjék és alkalmazásuk
WO2001072977A3 (en) Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
HUP0304053A2 (hu) Új expressziós vektorok és azok alkalmazása
HUP0300997A2 (hu) A MIA-fehérje alkalmazása immunterápiában
ATE278011T1 (de) Human dnase ii
HUP0004739A1 (hu) Presenilinekkel kölcsönhatásra képes fehérjéket kódoló nukleinsavak
HUP0200162A2 (hu) Haemophilus somnus transzferrin-kötő fehérjék klónozása és expresszálása
HUP0203801A2 (hu) Eljárás rekombináns adenovírusok előállítására és adenovírus-könyvtárak

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees