HUP0302479A2 - NF-kappa B gátló gyógyszerkészítmény, amely hatóanyagként helyettesített benzoesavszármazékot tartalmaz - Google Patents

NF-kappa B gátló gyógyszerkészítmény, amely hatóanyagként helyettesített benzoesavszármazékot tartalmaz

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Publication number
HUP0302479A2
HUP0302479A2 HU0302479A HUP0302479A HUP0302479A2 HU P0302479 A2 HUP0302479 A2 HU P0302479A2 HU 0302479 A HU0302479 A HU 0302479A HU P0302479 A HUP0302479 A HU P0302479A HU P0302479 A2 HUP0302479 A2 HU P0302479A2
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Hungary
Prior art keywords
group
substituted
active ingredient
benzoic acid
acid derivative
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HU0302479A
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English (en)
Inventor
Yoichi Nunokawa
Naohisa Ogou
Kenji Suzuki
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Daiichi Suntory Biomedical Research Limited
Daiichi Suntory Pharma Co., Ltd.
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Publication date
Application filed by Daiichi Suntory Biomedical Research Limited, Daiichi Suntory Pharma Co., Ltd. filed Critical Daiichi Suntory Biomedical Research Limited
Publication of HUP0302479A2 publication Critical patent/HUP0302479A2/hu

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Abstract

A találmány (I) általános képletű új, helyettesített benzoesav-származékra - a képletben R1 jelentése (II) általános képletű vagy(III) általános képletű csoport (amelyekben R3, R4 és R5 jelentéseegymástól függetlenül hidrogénatom, 1-6 szénatomos alkilcsoport vagy1-6 szénatomos alkoxicsoport, és R9 és R10 jelentése egymástólfüggetlenül hidrogénatom, 1-6 szénatomos alkilcsoport vagy 2-11szénatomos acilcsoport); R2 jelentése hidrogénatom, 1-6 szénatomosalkilcsoport, amely helyettesített lehet, 6-12 szénatomos arilcsoport,amely helyettesített lehet, 4-11 szénatomos heteroaril-csoport, amelyhelyettesített lehet, 7-14 szénatomos aralkilcsoport, amelyhelyettesített lehet, 5-13 szénatomos heteroarilalkil-csoport, amelyhelyettesített lehet, vagy 2-11 szénatomos acilcsoport; és X jelentésekarboxilcsoport, amely észterezett vagy amidált lehet, és a vegyületethatóanyagként tartalmazó NF-kB gátló készítményekre vonatkozik. Ó
HU0302479A 2001-03-27 2002-03-27 NF-kappa B gátló gyógyszerkészítmény, amely hatóanyagként helyettesített benzoesavszármazékot tartalmaz HUP0302479A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001091003 2001-03-27
PCT/JP2002/003017 WO2002076918A1 (en) 2001-03-27 2002-03-27 NF-λB INHIBITOR CONTAINING SUBSTITUTED BENZOIC ACID DERIVATIVE AS ACTIVE INGREDIENT

Publications (1)

Publication Number Publication Date
HUP0302479A2 true HUP0302479A2 (hu) 2003-11-28

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HU0302479A HUP0302479A2 (hu) 2001-03-27 2002-03-27 NF-kappa B gátló gyógyszerkészítmény, amely hatóanyagként helyettesített benzoesavszármazékot tartalmaz

Country Status (9)

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US (1) US7064124B2 (hu)
EP (1) EP1314712A4 (hu)
JP (1) JPWO2002076918A1 (hu)
KR (1) KR20030005417A (hu)
CN (1) CN1460097A (hu)
BR (1) BR0204678A (hu)
CA (1) CA2410816A1 (hu)
HU (1) HUP0302479A2 (hu)
WO (1) WO2002076918A1 (hu)

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WO2013058613A2 (ko) * 2011-10-21 2013-04-25 한국생명공학연구원 2-하이드록시아릴아마이드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 암 예방 또는 치료용 약학적 조성물
KR101434461B1 (ko) 2011-10-21 2014-09-01 한국생명공학연구원 2-하이드록시아릴아마이드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 암 예방 또는 치료용 약학적 조성물
EP3362436B1 (en) * 2015-09-14 2021-06-30 Universiteit Antwerpen Process for the catalytic directed cleavage of amide-containing compounds
JP6860551B2 (ja) * 2016-03-11 2021-04-14 武田薬品工業株式会社 芳香環化合物

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KR20030005417A (ko) 2003-01-17
BR0204678A (pt) 2003-04-29
EP1314712A4 (en) 2004-12-15
US20040122244A1 (en) 2004-06-24
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