HUP0301847A2 - Adatanszerin alkalmazása neurodegeneratív állapotok megelżzésére és kezelésére alkalmas gyógyszerkészítmények elżállítására - Google Patents
Adatanszerin alkalmazása neurodegeneratív állapotok megelżzésére és kezelésére alkalmas gyógyszerkészítmények elżállításáraInfo
- Publication number
- HUP0301847A2 HUP0301847A2 HU0301847A HUP0301847A HUP0301847A2 HU P0301847 A2 HUP0301847 A2 HU P0301847A2 HU 0301847 A HU0301847 A HU 0301847A HU P0301847 A HUP0301847 A HU P0301847A HU P0301847 A2 HUP0301847 A2 HU P0301847A2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- adatanserin
- prevention
- pharmaceutical compositions
- neurodegenerative conditions
- Prior art date
Links
- HPFLVTSWRFCPCV-UHFFFAOYSA-N adatanserin Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)NCCN(CC1)CCN1C1=NC=CC=N1 HPFLVTSWRFCPCV-UHFFFAOYSA-N 0.000 title 1
- 229950008881 adatanserin Drugs 0.000 title 1
- 230000000626 neurodegenerative effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- ORILYTVJVMAKLC-UHFFFAOYSA-N adamantane Chemical compound C1C(C2)CC3CC1CC2C3 ORILYTVJVMAKLC-UHFFFAOYSA-N 0.000 abstract 1
- 229910001573 adamantine Inorganic materials 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Processing Of Meat And Fish (AREA)
Abstract
A találmány neurodegeneratív rendellenességek, mégpedig krónikusfájdalom és más, rendellenes glutamát felszabadulással kapcsolatosrendellenesség kezelésére alkalmas gyógyszerkészítmények előállításáravonatkozik, A kezelés során adatanszerin vagy gyógyászatilagelfogadható sója terápiásan hatásos mennyiségét adják be az ilyenkezelésre szoruló betegnek. A találmány kiterjed az adamantinalkalmazására a fenti neurodegeneratív rendellenességek kezelésérealkalmas gyógyszerkészítmény előállítására is. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43921999A | 1999-11-12 | 1999-11-12 | |
PCT/US2000/030973 WO2001034136A2 (en) | 1999-11-12 | 2000-11-10 | Use of adatanserin for the treatment of neurodegenerative conditions |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0301847A2 true HUP0301847A2 (hu) | 2003-09-29 |
HUP0301847A3 HUP0301847A3 (en) | 2004-01-28 |
Family
ID=23743796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0301847A HUP0301847A3 (en) | 1999-11-12 | 2000-11-10 | Use of adatanserin for producing pharmaceutical compositions for the treatment and prevention of neurodegenerative conditions |
Country Status (22)
Country | Link |
---|---|
EP (2) | EP1547597A3 (hu) |
JP (1) | JP2003513915A (hu) |
KR (1) | KR100757226B1 (hu) |
CN (1) | CN100469368C (hu) |
AT (1) | ATE291919T1 (hu) |
AU (1) | AU773733B2 (hu) |
BR (1) | BR0015523A (hu) |
CA (1) | CA2390797A1 (hu) |
CZ (1) | CZ298535B6 (hu) |
DE (1) | DE60019166T2 (hu) |
EA (1) | EA006099B1 (hu) |
ES (1) | ES2235998T3 (hu) |
HK (1) | HK1046505B (hu) |
HU (1) | HUP0301847A3 (hu) |
IL (1) | IL149264A0 (hu) |
MX (1) | MXPA02004654A (hu) |
NO (1) | NO322371B1 (hu) |
NZ (1) | NZ518814A (hu) |
PL (1) | PL355014A1 (hu) |
PT (1) | PT1242089E (hu) |
WO (1) | WO2001034136A2 (hu) |
ZA (1) | ZA200204682B (hu) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60019166T2 (de) * | 1999-11-12 | 2006-05-11 | Wyeth | Verwendung von adatanserin zur behandlung von akuten neurodegenerativen erkrankungen |
WO2009082268A2 (ru) | 2007-12-21 | 2009-07-02 | Alla Chem, Llc | ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5441961A (en) * | 1992-08-27 | 1995-08-15 | Eli Lilly And Company | Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines |
US5877173A (en) * | 1996-08-28 | 1999-03-02 | Washington University | Preventing neuronal degeneration in Alzheimer's disease |
US5902815A (en) * | 1996-09-03 | 1999-05-11 | Washington University | Use of 5HT-2A serotonin agonists to prevent adverse effects of NMDA receptor hypofunction |
DE60019166T2 (de) * | 1999-11-12 | 2006-05-11 | Wyeth | Verwendung von adatanserin zur behandlung von akuten neurodegenerativen erkrankungen |
-
2000
- 2000-11-10 DE DE60019166T patent/DE60019166T2/de not_active Expired - Fee Related
- 2000-11-10 AU AU16567/01A patent/AU773733B2/en not_active Ceased
- 2000-11-10 JP JP2001536136A patent/JP2003513915A/ja not_active Withdrawn
- 2000-11-10 EA EA200200559A patent/EA006099B1/ru not_active IP Right Cessation
- 2000-11-10 IL IL14926400A patent/IL149264A0/xx unknown
- 2000-11-10 NZ NZ518814A patent/NZ518814A/en unknown
- 2000-11-10 PT PT00979157T patent/PT1242089E/pt unknown
- 2000-11-10 ES ES00979157T patent/ES2235998T3/es not_active Expired - Lifetime
- 2000-11-10 BR BR0015523-3A patent/BR0015523A/pt not_active Application Discontinuation
- 2000-11-10 CA CA002390797A patent/CA2390797A1/en not_active Abandoned
- 2000-11-10 HU HU0301847A patent/HUP0301847A3/hu unknown
- 2000-11-10 PL PL00355014A patent/PL355014A1/xx not_active IP Right Cessation
- 2000-11-10 EP EP05001510A patent/EP1547597A3/en not_active Withdrawn
- 2000-11-10 CZ CZ20021629A patent/CZ298535B6/cs not_active IP Right Cessation
- 2000-11-10 WO PCT/US2000/030973 patent/WO2001034136A2/en active IP Right Grant
- 2000-11-10 EP EP00979157A patent/EP1242089B1/en not_active Expired - Lifetime
- 2000-11-10 CN CNB008156085A patent/CN100469368C/zh not_active Expired - Fee Related
- 2000-11-10 AT AT00979157T patent/ATE291919T1/de not_active IP Right Cessation
- 2000-11-10 MX MXPA02004654A patent/MXPA02004654A/es active IP Right Grant
- 2000-11-10 KR KR1020027006067A patent/KR100757226B1/ko not_active IP Right Cessation
-
2002
- 2002-05-07 NO NO20022187A patent/NO322371B1/no not_active IP Right Cessation
- 2002-06-11 ZA ZA200204682A patent/ZA200204682B/en unknown
- 2002-11-08 HK HK02108123.1A patent/HK1046505B/zh not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |