HUP0204347A3 - Compounds having antitumor activity: process for their preparation and pharmaceutical compositions containing them and their use - Google Patents
Compounds having antitumor activity: process for their preparation and pharmaceutical compositions containing them and their useInfo
- Publication number
- HUP0204347A3 HUP0204347A3 HU0204347A HUP0204347A HUP0204347A3 HU P0204347 A3 HUP0204347 A3 HU P0204347A3 HU 0204347 A HU0204347 A HU 0204347A HU P0204347 A HUP0204347 A HU P0204347A HU P0204347 A3 HUP0204347 A3 HU P0204347A3
- Authority
- HU
- Hungary
- Prior art keywords
- compounds
- preparation
- pharmaceutical compositions
- compositions containing
- antitumor activity
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- AIDS & HIV (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN89MA2000 | 2000-02-03 | ||
| PCT/IB2001/000127 WO2001057026A1 (en) | 2000-02-03 | 2001-02-02 | Compounds having antitumor activity: process for their preparation and pharmaceutical compositions containing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0204347A2 HUP0204347A2 (en) | 2003-05-28 |
| HUP0204347A3 true HUP0204347A3 (en) | 2005-04-28 |
Family
ID=11097156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0204347A HUP0204347A3 (en) | 2000-02-03 | 2001-02-02 | Compounds having antitumor activity: process for their preparation and pharmaceutical compositions containing them and their use |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6410590B1 (hu) |
| EP (1) | EP1261604A1 (hu) |
| JP (1) | JP2003522166A (hu) |
| KR (1) | KR20030004342A (hu) |
| CN (1) | CN1416428A (hu) |
| AU (1) | AU3043101A (hu) |
| BG (1) | BG106985A (hu) |
| BR (1) | BR0108064A (hu) |
| CA (1) | CA2398996A1 (hu) |
| CZ (1) | CZ20022655A3 (hu) |
| HU (1) | HUP0204347A3 (hu) |
| IL (1) | IL150905A0 (hu) |
| MX (1) | MXPA02007513A (hu) |
| NO (1) | NO20023643L (hu) |
| NZ (1) | NZ520521A (hu) |
| RU (1) | RU2002123576A (hu) |
| WO (1) | WO2001057026A1 (hu) |
| ZA (1) | ZA200206112B (hu) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6576662B2 (en) * | 2000-05-05 | 2003-06-10 | Dr. Reddy's Laboratories Limited | Compounds having anticancer activity : process for their preparation and pharmaceutical compositions containing them |
| CN100430054C (zh) * | 2002-12-31 | 2008-11-05 | 北京大学第一医院 | 穿心莲二萜内酯在制备抑制血管生成药物中的应用 |
| CN100408571C (zh) * | 2003-02-25 | 2008-08-06 | 北京医工生物技术研究所 | 穿心莲内酯三马来酸半酯及其盐和它们的药物组合物 |
| KR20070026398A (ko) * | 2004-02-03 | 2007-03-08 | 우니베르시다드 오스뜨랄 데 칠레 | Ｐｐａｒ-감마 수용체의 활성화에 의한 자가면역 질환 및알츠하이머병의 치료에 유용한, 천심련으로부터 추출된랍단 디테르펜을 포함하는 조성물 |
| JP5049788B2 (ja) * | 2004-11-08 | 2012-10-17 | コーネル リサーチ ファンデーション インコーポレーティッド | ウイルス感染症を処置するためのアンドログラフォライド（ａｎｄｒｏｇｒａｐｈｏｌｉｄｅ）誘導体 |
| CN101129354B (zh) * | 2005-06-06 | 2011-02-02 | 河南大学 | 含有三乙酰穿心莲内酯的药物组合物及其医药用途 |
| JP2007176934A (ja) * | 2005-11-30 | 2007-07-12 | Kose Corp | 血小板活性化因子アセチルヒドロラーゼ機能調整剤 |
| CN101481375B (zh) * | 2005-12-07 | 2011-06-01 | 郑州大学 | 穿心莲内酯c15位取代系列衍生物及其制备方法 |
| CN100999520B (zh) * | 2007-01-05 | 2010-12-01 | 郑州大学 | 异穿心莲内酯类似物及其制备方法 |
| AU2008258958B2 (en) * | 2007-05-31 | 2013-05-16 | Suntory Holdings Limited | Anti-fatigue Agents and Oral Compositions Containing Andrographolide as Active Ingredient |
| CN100584841C (zh) | 2007-08-08 | 2010-01-27 | 暨南大学 | 穿心莲内酯衍生物及其在制药中的应用 |
| US20090117209A1 (en) * | 2007-11-02 | 2009-05-07 | Hutchison Medipharma Enterprises Limited | Andrographis paniculata extract |
| US9060994B2 (en) | 2011-12-21 | 2015-06-23 | Inno Biosciences, S.p.A. | Combination therapy with interferon and andrographolides for Multiple Sclerosis |
| CN102526026B (zh) * | 2012-02-10 | 2013-07-03 | 郑州大学 | 15-苄亚基-14-脱氧-11,12-脱氢穿心莲内酯衍生物在制备保肝药物中的用途 |
| EP3209658A1 (en) * | 2014-10-24 | 2017-08-30 | Biogen MA Inc. | Diterpenoid derivatives and methods of use thereof |
| CN106606506A (zh) * | 2015-10-21 | 2017-05-03 | 复旦大学 | 对映半日花烷型二萜在制备抗补体药物中的用途 |
| CN105954457A (zh) * | 2016-06-24 | 2016-09-21 | 广西灵峰药业有限公司 | 一种金香胶囊的生产质量控制方法 |
| CN109942520B (zh) * | 2019-04-10 | 2023-08-01 | 大理金明动物药业有限公司 | 穿心莲内酯磺化物及其制备方法与应用 |
| CN116898841A (zh) * | 2023-09-11 | 2023-10-20 | 中国中医科学院广安门医院 | 一种穿心莲内酯改构化合物l8或其衍生物的用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6388124A (ja) | 1986-09-30 | 1988-04-19 | Toyo Jozo Co Ltd | 抗腫瘍剤 |
| GB8917295D0 (en) | 1989-07-28 | 1989-09-13 | Ruffles Graham K | Anti-viral compositions |
| AU4376396A (en) | 1994-12-06 | 1996-06-26 | Paracelsian, Inc. | Use of andrographolide compounds to treat or prevent pathogenicity of diseases |
-
2001
- 2001-02-01 US US09/775,533 patent/US6410590B1/en not_active Expired - Fee Related
- 2001-02-02 HU HU0204347A patent/HUP0204347A3/hu unknown
- 2001-02-02 CN CN01806413A patent/CN1416428A/zh active Pending
- 2001-02-02 AU AU30431/01A patent/AU3043101A/en not_active Abandoned
- 2001-02-02 BR BR0108064-4A patent/BR0108064A/pt not_active IP Right Cessation
- 2001-02-02 MX MXPA02007513A patent/MXPA02007513A/es unknown
- 2001-02-02 KR KR1020027009978A patent/KR20030004342A/ko not_active Application Discontinuation
- 2001-02-02 EP EP01902573A patent/EP1261604A1/en not_active Withdrawn
- 2001-02-02 CA CA002398996A patent/CA2398996A1/en not_active Abandoned
- 2001-02-02 IL IL15090501A patent/IL150905A0/xx unknown
- 2001-02-02 NZ NZ520521A patent/NZ520521A/en unknown
- 2001-02-02 WO PCT/IB2001/000127 patent/WO2001057026A1/en not_active Application Discontinuation
- 2001-02-02 CZ CZ20022655A patent/CZ20022655A3/cs unknown
- 2001-02-02 JP JP2001557858A patent/JP2003522166A/ja active Pending
- 2001-02-02 RU RU2002123576/04A patent/RU2002123576A/ru not_active Application Discontinuation
-
2002
- 2002-07-31 NO NO20023643A patent/NO20023643L/no not_active Application Discontinuation
- 2002-07-31 ZA ZA200206112A patent/ZA200206112B/en unknown
- 2002-08-07 BG BG106985A patent/BG106985A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2002123576A (ru) | 2004-01-10 |
| CN1416428A (zh) | 2003-05-07 |
| AU3043101A (en) | 2001-08-14 |
| MXPA02007513A (es) | 2004-08-23 |
| BG106985A (en) | 2003-04-30 |
| KR20030004342A (ko) | 2003-01-14 |
| CZ20022655A3 (cs) | 2003-04-16 |
| WO2001057026A1 (en) | 2001-08-09 |
| IL150905A0 (en) | 2003-02-12 |
| CA2398996A1 (en) | 2001-08-09 |
| NO20023643L (no) | 2002-09-30 |
| ZA200206112B (en) | 2003-10-31 |
| NZ520521A (en) | 2004-05-28 |
| HUP0204347A2 (en) | 2003-05-28 |
| US6410590B1 (en) | 2002-06-25 |
| BR0108064A (pt) | 2002-10-29 |
| EP1261604A1 (en) | 2002-12-04 |
| NO20023643D0 (no) | 2002-07-31 |
| JP2003522166A (ja) | 2003-07-22 |
| US20020032229A1 (en) | 2002-03-14 |
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