HUP0202339A2 - Kortizol antagonisták alkalmazása szívelégtelenség kezelésére - Google Patents

Kortizol antagonisták alkalmazása szívelégtelenség kezelésére

Info

Publication number
HUP0202339A2
HUP0202339A2 HU0202339A HUP0202339A HUP0202339A2 HU P0202339 A2 HUP0202339 A2 HU P0202339A2 HU 0202339 A HU0202339 A HU 0202339A HU P0202339 A HUP0202339 A HU P0202339A HU P0202339 A2 HUP0202339 A2 HU P0202339A2
Authority
HU
Hungary
Prior art keywords
treatment
heat failure
cortisol
cortisol antagonists
antagonists
Prior art date
Application number
HU0202339A
Other languages
English (en)
Inventor
Rebecca Gardner
Per Marin
Sten Sorensen
Original Assignee
Cortendo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortendo Ab filed Critical Cortendo Ab
Publication of HUP0202339A2 publication Critical patent/HUP0202339A2/hu
Publication of HUP0202339A3 publication Critical patent/HUP0202339A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgya kortizol antagonista - péládul ketokonazol -alkalmazása szívelégtelenséggel kapcsolatos egy vagy több tünetkezelésére szolgáló gyógyszer előállítása, ahol a tünet az alábbicsoportból kerül ki: alsó végtagi ödéma, tüdőödéma, nehézlégzés,májnagyobbodás, szívfrekvencia-növekedés, csökkent kilököttvértérfogat, légszomj és a fizikai terhelés intoleranciája. Ó
HU0202339A 1999-07-02 2000-07-03 Use of cortisol antagonists in the treatment of heat failure HUP0202339A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9915625.9A GB9915625D0 (en) 1999-07-02 1999-07-02 Method

Publications (2)

Publication Number Publication Date
HUP0202339A2 true HUP0202339A2 (hu) 2002-11-28
HUP0202339A3 HUP0202339A3 (en) 2004-12-28

Family

ID=10856599

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202339A HUP0202339A3 (en) 1999-07-02 2000-07-03 Use of cortisol antagonists in the treatment of heat failure

Country Status (16)

Country Link
US (1) US6881739B1 (hu)
EP (1) EP1196152A1 (hu)
JP (1) JP4039482B2 (hu)
KR (1) KR100623166B1 (hu)
AU (1) AU780152B2 (hu)
CA (1) CA2375751A1 (hu)
CZ (1) CZ300888B6 (hu)
GB (1) GB9915625D0 (hu)
HU (1) HUP0202339A3 (hu)
MX (1) MXPA01013465A (hu)
NO (1) NO324395B1 (hu)
NZ (1) NZ516239A (hu)
PL (1) PL202859B1 (hu)
RU (1) RU2245712C2 (hu)
SK (1) SK285845B6 (hu)
WO (1) WO2001001971A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6642236B1 (en) * 1998-12-14 2003-11-04 Cortendo Ab Methods for prophylactic treatment of cardiovascular disease with inhibitor of cortisol synthesis
SE0001899D0 (sv) 2000-05-22 2000-05-22 Pharmacia & Upjohn Ab New compounds
GB0118300D0 (en) * 2001-07-26 2001-09-19 Cortendo Ab Formulations
RS44304A (en) 2001-11-22 2007-06-04 Biovitrum Ab., Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
ATE419037T1 (de) * 2002-09-04 2009-01-15 Fraunhofer Ges Forschung Verwendung eines mittel zur therapie der herzhypertrophie
CA2594433C (en) * 2005-01-10 2014-12-30 Cortendo Invest Ab Compositions comprising the 2s,4r ketoconazole enantiomer for treating diabetes, metabolic syndrome and other conditions
WO2008042898A2 (en) 2006-10-02 2008-04-10 Cortendo Invest, Ab Ketoconazole enantiomer in humans
US20150005269A1 (en) * 2012-01-03 2015-01-01 Rhode Island Hospital Treatment of Heart Failure and Sudden Cardiac Death

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US460314A (en) * 1891-09-29 George a
US4603141A (en) * 1984-11-30 1986-07-29 Giles Thomas D Oral clonidine treatment of congestive heart failure
US5175144A (en) * 1988-11-29 1992-12-29 The Johns Hopkins University Method of retarding the progression of chronic renal failure
GB9014221D0 (en) 1990-06-26 1990-08-15 Janssen Pharmaceutica Nv Method of treating alopecia
WO1994016710A1 (en) 1993-01-21 1994-08-04 Janssen Pharmaceutica N.V. Topical ketoconazole compositions
US5565478A (en) * 1994-03-14 1996-10-15 The United States Of America As Represented By The Department Of Health & Human Services Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs
US5756469A (en) * 1996-07-26 1998-05-26 Beale; Paxton K. Composition of pyruvate and anti-cortisol compounds and method for increasing protein concentration in a mammal
WO1999017779A1 (en) * 1997-10-06 1999-04-15 The Board Of Trustees Of Leland Stanford Jr. University Methods for treating psychosis associated with glucocorticoid related dysfunction
SE9803272D0 (sv) * 1998-09-25 1998-09-25 Kerstin Uvnaes Moberg A drug for cell regeneration
WO2000024402A1 (fr) * 1998-10-27 2000-05-04 Roumen Antonov Utilisation d'antifongiques dans le traitement des scleroses

Also Published As

Publication number Publication date
AU780152B2 (en) 2005-03-03
PL202859B1 (pl) 2009-07-31
HUP0202339A3 (en) 2004-12-28
US6881739B1 (en) 2005-04-19
PL352479A1 (en) 2003-08-25
NO20020008L (no) 2002-02-27
KR100623166B1 (ko) 2006-09-11
NO324395B1 (no) 2007-10-01
RU2245712C2 (ru) 2005-02-10
NZ516239A (en) 2004-04-30
CZ300888B6 (cs) 2009-09-02
AU5695600A (en) 2001-01-22
NO20020008D0 (no) 2002-01-02
SK285845B6 (sk) 2007-09-06
JP4039482B2 (ja) 2008-01-30
GB9915625D0 (en) 1999-09-01
CA2375751A1 (en) 2001-01-11
JP2003503448A (ja) 2003-01-28
MXPA01013465A (es) 2003-09-04
SK19332001A3 (sk) 2002-12-03
WO2001001971A1 (en) 2001-01-11
CZ20014684A3 (cs) 2002-11-13
KR20020038600A (ko) 2002-05-23
EP1196152A1 (en) 2002-04-17

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