HUP0201686A3 - Multilayered tablet for administration of a fixed combination of tramadol and diclofenac - Google Patents

Multilayered tablet for administration of a fixed combination of tramadol and diclofenac

Info

Publication number
HUP0201686A3
HUP0201686A3 HU0201686A HUP0201686A HUP0201686A3 HU P0201686 A3 HUP0201686 A3 HU P0201686A3 HU 0201686 A HU0201686 A HU 0201686A HU P0201686 A HUP0201686 A HU P0201686A HU P0201686 A3 HUP0201686 A3 HU P0201686A3
Authority
HU
Hungary
Prior art keywords
tramadol
diclofenac
administration
fixed combination
multilayered tablet
Prior art date
Application number
HU0201686A
Other languages
English (en)
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7911585&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0201686(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of HUP0201686A2 publication Critical patent/HUP0201686A2/hu
Publication of HUP0201686A3 publication Critical patent/HUP0201686A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
HU0201686A 1999-06-17 2000-06-13 Multilayered tablet for administration of a fixed combination of tramadol and diclofenac HUP0201686A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19927688A DE19927688A1 (de) 1999-06-17 1999-06-17 Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac

Publications (2)

Publication Number Publication Date
HUP0201686A2 HUP0201686A2 (en) 2002-09-28
HUP0201686A3 true HUP0201686A3 (en) 2005-07-28

Family

ID=7911585

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0201686A HUP0201686A3 (en) 1999-06-17 2000-06-13 Multilayered tablet for administration of a fixed combination of tramadol and diclofenac

Country Status (12)

Country Link
US (1) US6558701B2 (hu)
EP (1) EP1183015B1 (hu)
JP (1) JP4945041B2 (hu)
AT (1) ATE279915T1 (hu)
AU (1) AU770777B2 (hu)
CA (1) CA2377167C (hu)
DE (2) DE19927688A1 (hu)
ES (1) ES2231221T3 (hu)
HU (1) HUP0201686A3 (hu)
MX (1) MXPA01013047A (hu)
PT (1) PT1183015E (hu)
WO (1) WO2000078289A1 (hu)

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US8173164B2 (en) * 1999-06-17 2012-05-08 Gruenenthal Gmbh Oral administration forms for administering a fixed tramadol and diclofenac combination
HUP0203623A2 (hu) * 1999-08-31 2003-02-28 Grünenthal GmbH Tramadol-szacharinátot tartalmazó, késleltetett hatású adagolási forma és alkalmazása
DE19940944B4 (de) 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen
WO2003013245A1 (en) 2001-08-07 2003-02-20 Wisconsin Alumni Research Foundation Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
US20050027016A1 (en) 2002-02-07 2005-02-03 Fahl Kathleen L Polyamine compounds and compositions for use in conjection with cancer therapy
US8679533B2 (en) 2002-07-25 2014-03-25 Pharmacia Corporation Pramipexole once-daily dosage form
US20050226926A1 (en) * 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
JP4343948B2 (ja) 2003-04-29 2009-10-14 オレキシジェン・セラピューティクス・インコーポレーテッド 体重減少に影響を及ぼすための組成物
US20050013863A1 (en) 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
WO2005014524A2 (en) 2003-08-07 2005-02-17 Wisconsin Alumni Research Foundation Amino thiol compounds and compositions for use in conjunction with cancer therapy
PL1667664T3 (pl) * 2003-09-24 2017-06-30 Novartis Consumer Health S.A. Powlekane tabletki diklofenaku
US8157788B2 (en) * 2003-11-06 2012-04-17 Paolo L. Manfredi Multi-site drug delivery platform
US7318935B2 (en) * 2004-05-21 2008-01-15 Accu-Break Technologies, Inc. Pharmaceutical tablets with active and inactive segments
US7838031B2 (en) 2004-05-21 2010-11-23 Lawrence Solomon Method of administering a partial dose using a segmented pharmaceutical tablet
US7713547B2 (en) 2004-05-21 2010-05-11 Accu-Break Pharmaceuticals, Inc. Method of administering a partial dose of a segmented pharmaceutical tablet
CA2566310C (en) * 2004-05-21 2014-05-13 Lawrence Solomon Scored pharmaceutical tablets comprising a plurality of segments
US20060003000A1 (en) * 2004-07-01 2006-01-05 Lawrence Solomon Adhesively bonded dosage form
US7329418B2 (en) * 2004-05-21 2008-02-12 Accu Break Technologies, Inc. Pharmaceutical tablets having height greater than width
US7780985B2 (en) * 2005-07-12 2010-08-24 Accu-Break Technologies, Inc. Tablets having a printed separation mark to guide breaking
US7622137B2 (en) * 2004-05-21 2009-11-24 Accu-Break Technologies, Inc. Dosage forms contained within a capsule or sachet
WO2006015943A2 (en) * 2004-08-13 2006-02-16 Boehringer Ingelheim International Gmbh Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
EP2345407A1 (en) * 2004-08-13 2011-07-20 Boehringer Ingelheim International GmbH Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
AR051950A1 (es) * 2004-11-10 2007-02-21 Osmotica Pharmaceutical Argent Comprimido multicapa con capas que se separan
KR100714616B1 (ko) * 2005-06-23 2007-05-07 삼성전기주식회사 지수 함수 발생기 및 이를 이용한 가변 이득 증폭기
WO2007008752A2 (en) * 2005-07-07 2007-01-18 Farnam Companies, Inc. Sustained release pharmaceutical compositions for highly water soluble drugs
CA2616204C (en) * 2005-09-09 2015-12-01 Labopharm Inc. Sustained drug release composition
JP5259413B2 (ja) * 2005-11-18 2013-08-07 エーシーシーユー−ブレイク テクノロジーズ，インク． セグメント化した薬の剤形
US8691272B2 (en) * 2005-12-30 2014-04-08 Intelgenx Corp. Multilayer tablet
WO2007090881A2 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Modified release formulation
US20090098202A1 (en) * 2006-02-10 2009-04-16 Boehringer Ingelheim International Gmbh Extended Release Formulation
US20070237815A1 (en) * 2006-04-06 2007-10-11 Lawrence Solomon Dosage forms and methods comprising amlodipine and chlorthalidone
US20090280171A1 (en) * 2006-04-13 2009-11-12 Accu-Break Technologies, Inc. Method of treatment with predictably breakable pharmaceutical tablets
BRPI0602179A (pt) * 2006-06-08 2008-01-22 Biolab Sanus Farmaceutica Ltda composição farmacêutica compreendendo ciclobenzaprina e aceclofenaco em combinação
WO2007149860A1 (en) * 2006-06-19 2007-12-27 Accu-Break Technologies, Inc. Segmented pharmaceutical dosage forms
WO2008021875A2 (en) * 2006-08-08 2008-02-21 Accu-Break Technologies, Inc. Pharmaceutical tablets containing a plurality of active segments
DK2089005T3 (da) * 2006-11-09 2010-07-19 Orexigen Therapeutics Inc Lagdelte farmaceutiske formuleringer omfattende et hurtigt opløsende mellemlag
JP2010511627A (ja) * 2006-11-30 2010-04-15 エーシーシーユー−ブレイク テクノロジーズ，インク． 分割可能な浸透性剤形及びその使用方法
EP2057984B1 (de) * 2007-11-09 2010-01-20 Acino Pharma AG Retardtabletten mit Hydromorphon
CA2725930A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
EP2177215A1 (en) 2008-10-17 2010-04-21 Laboratorios Del. Dr. Esteve, S.A. Co-crystals of tramadol and NSAIDs
US20100247586A1 (en) * 2009-03-27 2010-09-30 Andreas Hugerth Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties
EP2266948A1 (en) 2009-06-16 2010-12-29 Laboratorios Del. Dr. Esteve, S.A. Salts of tramadol and diflunisal and their crystal form in the treatment of pain
EP2281558A1 (en) 2009-08-06 2011-02-09 Laboratorios Del. Dr. Esteve, S.A. Pharmaceutical compounds of O-Desmethyl-Tramadol and COX-inhibitors
EP2311446A1 (en) 2009-10-16 2011-04-20 Laboratorios Del. Dr. Esteve, S.A. Compositions comprising Tramadol and Celecoxib in the treatment of pain
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
CN102724878A (zh) 2010-01-11 2012-10-10 奥雷西根治疗公司 在重度抑郁症患者中提供体重减轻疗法的方法
EP2353594A1 (en) 2010-02-09 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Compositions comprising tramadol and the co-crystal of celecoxib and L-proline in the treatment of pain
EP2593096A4 (en) * 2010-07-12 2014-02-26 Yung Shin Pharm Ind Co Ltd DICLOFENAC SALT OF TRAMADOL
US20120015031A1 (en) 2010-07-14 2012-01-19 Grunenthal Gmbh Novel gastro-retentive dosage forms
US20120040008A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
EA201492175A1 (ru) 2012-06-06 2015-10-30 Орексиджен Терапьютикс, Инк. Способы лечения избыточного веса и ожирения
JP7174441B2 (ja) * 2017-09-15 2022-11-17 クリスタルジェノミクス・インコーポレイテッド ポルマコキシブ及びトラマドールを含有する急性・慢性疼痛治療用薬剤学的組成物
KR102631399B1 (ko) 2018-03-30 2024-02-01 씨지인바이츠 주식회사 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물
WO2020039456A1 (en) * 2018-08-20 2020-02-27 Mylan Laboratories Limited Tramadol hbr-celecoxib co-crystal

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8521350D0 (en) * 1985-08-28 1985-10-02 Euro Celtique Sa Analgesic composition
AU661723B2 (en) * 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
IT1282576B1 (it) * 1996-02-06 1998-03-31 Jagotec Ag Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
JP3049483B2 (ja) * 1996-05-02 2000-06-05 和夫 小笠原 ストレッチ器具
DE19710008A1 (de) * 1997-03-12 1998-09-17 Basf Ag Feste, mindestens zweiphasige Zubereitungsformen eines Opioid-Analgeticums mit verzögerter Freisetzung
DE19732928C2 (de) * 1997-07-31 2000-05-18 Gruenenthal Gmbh Verwendung substituierter Imidazolidin-2,4-dion-Verbindungen als Schmerzmittel
RS49982B (sr) * 1997-09-17 2008-09-29 Euro-Celtique S.A., Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
US6284273B1 (en) * 1998-02-24 2001-09-04 Vincent Lenaerts Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds

Also Published As

Publication number Publication date
HUP0201686A2 (en) 2002-09-28
JP4945041B2 (ja) 2012-06-06
US6558701B2 (en) 2003-05-06
EP1183015B1 (de) 2004-10-20
US20020132850A1 (en) 2002-09-19
JP2003502358A (ja) 2003-01-21
PT1183015E (pt) 2005-02-28
DE19927688A1 (de) 2000-12-21
CA2377167A1 (en) 2000-12-28
CA2377167C (en) 2009-06-09
EP1183015A1 (de) 2002-03-06
AU770777B2 (en) 2004-03-04
ES2231221T3 (es) 2005-05-16
ATE279915T1 (de) 2004-11-15
MXPA01013047A (es) 2002-06-04
DE50008336D1 (de) 2004-11-25
WO2000078289A1 (de) 2000-12-28
AU5972200A (en) 2001-01-09

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees