HUP0201083A2 - Új atorvastatinsók és az azokat tartalmazó gyógyszerkészítmények - Google Patents

Új atorvastatinsók és az azokat tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0201083A2
HUP0201083A2 HU0201083A HUP0201083A HUP0201083A2 HU P0201083 A2 HUP0201083 A2 HU P0201083A2 HU 0201083 A HU0201083 A HU 0201083A HU P0201083 A HUP0201083 A HU P0201083A HU P0201083 A2 HUP0201083 A2 HU P0201083A2
Authority
HU
Hungary
Prior art keywords
atorvastatin
salt
lysine
characteristic bands
shows characteristic
Prior art date
Application number
HU0201083A
Other languages
English (en)
Hungarian (hu)
Inventor
Péter Erdélyi
János Fischer
Krisztina Vukics
Béla Hegedűs
Károly Tihanyi
Mónika Vastag
Sándorné dr. Bálint
Krisztina Lánczos
Sándor Lévai
Original Assignee
Richter Gedeon Vegyészeti Gyár Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyészeti Gyár Rt. filed Critical Richter Gedeon Vegyészeti Gyár Rt.
Priority to HU0201083A priority Critical patent/HUP0201083A2/hu
Publication of HU0201083D0 publication Critical patent/HU0201083D0/hu
Priority to AU2003241060A priority patent/AU2003241060A1/en
Priority to PT03730380T priority patent/PT1490333E/pt
Priority to AT03730380T priority patent/ATE455761T1/de
Priority to DK03730380.7T priority patent/DK1490333T3/da
Priority to SI200331777T priority patent/SI1490333T1/sl
Priority to DE60331051T priority patent/DE60331051D1/de
Priority to ES03730380T priority patent/ES2339935T3/es
Priority to EP03730380A priority patent/EP1490333B1/en
Priority to PCT/HU2003/000024 priority patent/WO2003082816A1/en
Publication of HUP0201083A2 publication Critical patent/HUP0201083A2/hu
Priority to CY20101100235T priority patent/CY1109882T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU0201083A 2002-03-28 2002-03-28 Új atorvastatinsók és az azokat tartalmazó gyógyszerkészítmények HUP0201083A2 (hu)

Priority Applications (11)

Application Number Priority Date Filing Date Title
HU0201083A HUP0201083A2 (hu) 2002-03-28 2002-03-28 Új atorvastatinsók és az azokat tartalmazó gyógyszerkészítmények
PCT/HU2003/000024 WO2003082816A1 (en) 2002-03-28 2003-03-27 New atorvastatin salts and pharmaceutical compositions containing them
DK03730380.7T DK1490333T3 (da) 2002-03-28 2003-03-27 Nye atorvastatinsalte og farmaceutiske sammensætninger indeholdende dem
PT03730380T PT1490333E (pt) 2002-03-28 2003-03-27 Novos sais de atorvastatina e composições farmacêuticas que os contêm
AT03730380T ATE455761T1 (de) 2002-03-28 2003-03-27 Neue atorvastatinsalze und pharmazeutische zusammensetzungen, die diese enthalten
AU2003241060A AU2003241060A1 (en) 2002-03-28 2003-03-27 New atorvastatin salts and pharmaceutical compositions containing them
SI200331777T SI1490333T1 (sl) 2002-03-28 2003-03-27 Nove soli atorvastatina in farmacevtski sestavki, ki jih vsebujejo
DE60331051T DE60331051D1 (de) 2002-03-28 2003-03-27 Neue atorvastatinsalze und pharmazeutische zusammensetzungen, die diese enthalten
ES03730380T ES2339935T3 (es) 2002-03-28 2003-03-27 Nuevas sales de atorvastatina y composiciones farmaceuticas que las contienen.
EP03730380A EP1490333B1 (en) 2002-03-28 2003-03-27 New atorvastatin salts and pharmaceutical compositions containing them
CY20101100235T CY1109882T1 (el) 2002-03-28 2010-03-11 Νεα αλατα ατορβαστατινης και φαρμακευτικες συνθεσεις που τα περιεχουν

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0201083A HUP0201083A2 (hu) 2002-03-28 2002-03-28 Új atorvastatinsók és az azokat tartalmazó gyógyszerkészítmények

Publications (2)

Publication Number Publication Date
HU0201083D0 HU0201083D0 (enExample) 2002-05-29
HUP0201083A2 true HUP0201083A2 (hu) 2004-06-28

Family

ID=89980299

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0201083A HUP0201083A2 (hu) 2002-03-28 2002-03-28 Új atorvastatinsók és az azokat tartalmazó gyógyszerkészítmények

Country Status (11)

Country Link
EP (1) EP1490333B1 (enExample)
AT (1) ATE455761T1 (enExample)
AU (1) AU2003241060A1 (enExample)
CY (1) CY1109882T1 (enExample)
DE (1) DE60331051D1 (enExample)
DK (1) DK1490333T3 (enExample)
ES (1) ES2339935T3 (enExample)
HU (1) HUP0201083A2 (enExample)
PT (1) PT1490333E (enExample)
SI (1) SI1490333T1 (enExample)
WO (1) WO2003082816A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227041B1 (en) * 2003-03-24 2010-05-28 Richter Gedeon Nyrt Process for the synthesis of amorphous atorvastatin calcium
US20040248957A1 (en) 2003-05-16 2004-12-09 Ambit Biosciences Corporation Heterocyclic compounds and uses thereof
CA2551549A1 (en) 2003-12-29 2005-07-14 Lek Pharmaceuticals D.D. Process for preparing amorphous (4r-cis)-6-[2-[3-phenyl-4-(phenylcarbamoyl)-2-(4-fluorophenyl)-5-(1-methylethyl)-pyrrol-1-yl]-ethyl]-2,2-dimethyl-[1,3]-dioxane-4-yl-acetic acid
FR2869539B1 (fr) * 2004-04-29 2008-08-08 Univ Paris Descartes Compositions pharmaceutiques pour la prevention et le traitement de l'atherosclerose
EP3581564A1 (en) * 2004-05-05 2019-12-18 Pfizer Products Inc. Diethylamine salt forms of [r-(r*,r*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid
WO2006054308A2 (en) * 2004-11-22 2006-05-26 Dexcel Pharma Technologies Ltd. Stable atorvastatin formulations
EP1898922A4 (en) * 2005-07-04 2012-03-14 Ramu Krishnan MEDICINE OR IMPROVED PHARMACEUTICAL COMPOUNDS AND PREPARATION THEREOF
US8080672B2 (en) 2005-12-13 2011-12-20 Teva Pharmaceutical Industries Ltd. Crystal form of atorvastatin hemi-calcium and processes for preparation thereof
WO2011089559A1 (en) * 2010-01-22 2011-07-28 Orchid Chemicals And Pharmaceuticals Limited A novel polymorphic form of atorvastatin salts
MX2010011006A (es) * 2010-10-06 2012-04-18 Senosiain S A De C V Lab Nueva sal de un derivado de pirimidina.
CN103274985B (zh) * 2010-12-03 2016-03-09 上海科州药物研发有限公司 一种阿托伐他汀氨基酸盐
WO2013083674A1 (de) * 2011-12-08 2013-06-13 Hexal Ag Neue pharmazeutische statin-zusammensetzung
CN103232398B (zh) * 2012-04-28 2016-04-06 上海科州药物研发有限公司 一种瑞舒伐他汀氨基酸盐及其制备方法和应用
CN105246472B (zh) * 2013-03-15 2018-10-12 武汉朗来科技发展有限公司 含有鸟氨酸和/或门冬氨酸的组合物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9609872A (pt) * 1995-07-17 1999-03-23 Warner Lambert Co Hemi sal de cálcio de ácido (R-(R*R*)]-2-(4-fluorfenil-)-beta delta-diidróxi-5-(1-metiletil)-3-fenil-4- [(fenilamino) carbonil]-1H- pirrol-1heptanóico (atorvasta-tina)c ristalino
CA2406574C (en) * 2000-04-10 2006-12-05 Teva Pharmaceutical Industries, Ltd. Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids

Also Published As

Publication number Publication date
ATE455761T1 (de) 2010-02-15
ES2339935T3 (es) 2010-05-27
EP1490333A1 (en) 2004-12-29
PT1490333E (pt) 2010-03-04
SI1490333T1 (sl) 2010-04-30
DK1490333T3 (da) 2010-05-25
HU0201083D0 (enExample) 2002-05-29
CY1109882T1 (el) 2014-09-10
WO2003082816A1 (en) 2003-10-09
AU2003241060A1 (en) 2003-10-13
DE60331051D1 (de) 2010-03-11
EP1490333B1 (en) 2010-01-20

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: RICHTER GEDEON NYRT., HU

Free format text: FORMER OWNER(S): RICHTER GEDEON VEGYESZETI GYAR RT., HU

FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished