HUP0103160A2 - Pulmonalis betegségek kezelésére alkalmas PDE4 inhibítort tartalmazó gyógyászati készítmények - Google Patents

Pulmonalis betegségek kezelésére alkalmas PDE4 inhibítort tartalmazó gyógyászati készítmények

Info

Publication number
HUP0103160A2
HUP0103160A2 HU0103160A HUP0103160A HUP0103160A2 HU P0103160 A2 HUP0103160 A2 HU P0103160A2 HU 0103160 A HU0103160 A HU 0103160A HU P0103160 A HUP0103160 A HU P0103160A HU P0103160 A2 HUP0103160 A2 HU P0103160A2
Authority
HU
Hungary
Prior art keywords
pulmonary diseases
pharmaceutical compositions
pde4 inhibitor
treating pulmonary
diseases containing
Prior art date
Application number
HU0103160A
Other languages
English (en)
Inventor
Richard Nieman
Anthony S. Rebuck
Theodore J. Torphy
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of HUP0103160A2 publication Critical patent/HUP0103160A2/hu
Publication of HUP0103160A3 publication Critical patent/HUP0103160A3/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány pulmonalis betegségek tüneteinek kezelésére vagycsökkentésére, illetve a pulmonalis betegségek súlyosságánakkezelésére vagy csökkentésére szolgáló gyógyszerészeti kompozíciókravonatkozik. Közelebbről a találmány foszfodiészteráz-4 (PDE4) általmediált pulmonalis betegségek kezelésére szolgáló kompozíciókravonatkozik. Ó
HU0103160A 1998-08-26 1999-08-24 Pharmaceutical compositions for treating pulmonary diseases containing pde4 inhibitor HUP0103160A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9797398P 1998-08-26 1998-08-26
PCT/US1999/019332 WO2000012078A1 (en) 1998-08-26 1999-08-24 Therapies for treating pulmonary diseases

Publications (2)

Publication Number Publication Date
HUP0103160A2 true HUP0103160A2 (hu) 2002-01-28
HUP0103160A3 HUP0103160A3 (en) 2002-11-28

Family

ID=22266001

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103160A HUP0103160A3 (en) 1998-08-26 1999-08-24 Pharmaceutical compositions for treating pulmonary diseases containing pde4 inhibitor

Country Status (21)

Country Link
US (2) US6288118B1 (hu)
EP (1) EP1107747A4 (hu)
JP (1) JP2002523452A (hu)
KR (1) KR20010072931A (hu)
CN (1) CN1314811A (hu)
AR (1) AR022072A1 (hu)
AU (1) AU754379B2 (hu)
BR (1) BR9913152A (hu)
CA (1) CA2341488A1 (hu)
CZ (1) CZ293735B6 (hu)
DZ (1) DZ2876A1 (hu)
HU (1) HUP0103160A3 (hu)
IL (1) IL141335A0 (hu)
MA (1) MA26302A1 (hu)
MY (1) MY126544A (hu)
NO (1) NO20010882D0 (hu)
NZ (1) NZ527232A (hu)
PE (1) PE20001032A1 (hu)
PL (1) PL346271A1 (hu)
TR (1) TR200100500T2 (hu)
WO (1) WO2000012078A1 (hu)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6525018B1 (en) * 1999-05-17 2003-02-25 The General Hospital Corp. Treating eye disorders using intestinal trefoil proteins
US6624181B1 (en) 1997-02-28 2003-09-23 Altana Pharma Ag Synergistic combination
US20030186882A1 (en) * 2001-07-31 2003-10-02 Podolsky Daniel K. Methods and compositions for treating and preventing distal bowel lesions
US20030185838A1 (en) * 2001-11-28 2003-10-02 Podolsky Daniel K. Methods and compositions for treating lesions of the respiratory epithelium
NZ527232A (en) * 1998-08-26 2005-03-24 Smithkline Beecham Corp A composition contaning a PDE 4 inhibitor and a beta adrenergic bronchodilator useful for treating pulmonary diseases
US8933032B2 (en) 1998-10-20 2015-01-13 Children's Hospital Medical Center Surfactant protein D for the treatment of disorders associated with lung injury
EP2193808A1 (en) * 1999-08-21 2010-06-09 Nycomed GmbH Synergistic combination
SK17052002A3 (sk) 2000-06-05 2003-12-02 Altana Pharma Ag Pyridazinónové zlúčeniny, farmaceutický prostriedok s ich obsahom a ich použitie
US20040171544A1 (en) * 2001-04-24 2004-09-02 Barker Nicholas P. Trefoil domain-containing polypeptides and uses thereof
US20030105016A1 (en) * 2001-09-06 2003-06-05 Podolsky Daniel K. Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions
US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
US20060189526A1 (en) * 2002-04-24 2006-08-24 Podolsky Daniel K Compositions containing an intestinal trefoil peptide and a mucoadhesive
US20030181384A1 (en) * 2001-09-06 2003-09-25 Podolsky Daniel K. Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions
US20030185839A1 (en) * 2001-10-05 2003-10-02 Podolsky Daniel K. Methods and compositions for treating dermal lesions
MXPA04003267A (es) * 2001-10-05 2004-07-08 Gen Hospital Corp Metodos y composiciones para tratar lesiones dermicas.
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
JP2005532988A (ja) * 2001-11-28 2005-11-04 ザ ジェネラル ホスピタル コーポレーション 呼吸上皮の病変を治療するための方法および組成物
GB0129395D0 (en) * 2001-12-07 2002-01-30 Pfizer Ltd Pharmaceutical combination
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
CN1655675A (zh) * 2002-03-26 2005-08-17 综合医院公司 利用三叶肽的联合治疗
NZ536918A (en) * 2002-05-07 2006-09-29 Altana Pharma Ag Combination of pantoprazole and a respiratory agent for the treatment of respiratory diseases
MXPA04011018A (es) * 2002-05-07 2005-01-25 Altana Pharma Ag Nueva combinacion de inhibidores reversibles de la bomba de protones y productos terapueticos para tratar trastornos de las vias respiratorias.
DE10220458A1 (de) * 2002-05-07 2003-11-27 Altana Pharma Ag Kombination zur Behandlung von Atemwegserkrankungen
DE10220459A1 (de) * 2002-05-07 2003-11-27 Byk Gulden Lomberg Chem Fab Neue Kombination zur Behandlung von Atemwegserkrankungen
US20060188471A1 (en) * 2002-10-31 2006-08-24 Podolsky Daniel K Methods of treating epithelial lesions
MXPA05005438A (es) * 2002-11-27 2005-08-03 Altana Pharma Ag Combinacion sinergica que comprende roflumilast y (r, r) -formoterol.
RS51081B (sr) * 2002-11-27 2010-10-31 Nycomed Gmbh. Nova sinergistička kombinacija koja uključuje roflumilast i formoterol
KR101179012B1 (ko) 2003-03-10 2012-09-03 니코메드 게엠베하 로플루미라스트 신규한 제조 방법
WO2004087151A1 (ja) * 2003-03-31 2004-10-14 Kyowa Hakko Kogyo Co., Ltd. 医薬組成物
SE527200C2 (sv) * 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser av formaterol och fluticason
WO2005123072A1 (en) * 2004-06-14 2005-12-29 Sepracor Inc. Methods and compositions for the treatment of pulmonary diseases
US20090035224A1 (en) * 2004-06-14 2009-02-05 Sepracor Inc. Methods of Using Albuterol and Calcium Activated Potassium Channel Openers
AU2006224619B2 (en) 2005-03-16 2012-06-07 Takeda Gmbh Taste masked dosage form containing roflumilast
DE102005030733A1 (de) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
US20090182035A1 (en) * 2007-04-11 2009-07-16 Alcon Research, Ltd. Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
CA2682730A1 (en) * 2007-04-11 2008-10-23 Alcon Research, Ltd. Use of an inhibitor of tnf.alpha. plus an antihistamine to treat allergic rhinitis and allergic conjunctivitis
CN107243076A (zh) * 2009-04-22 2017-10-13 印第安那大学科技研究公司 用于治疗慢性阻塞性肺病和哮喘的组合物和方法
RU2012117141A (ru) * 2009-10-01 2013-11-10 Алькон Рисерч, Лтд. Композиции олопатадина и способы их применения
KR101035488B1 (ko) * 2009-10-05 2011-05-20 숭실대학교산학협력단 자동차 블랙박스 영상물 수집 방법
US8771693B2 (en) 2009-10-27 2014-07-08 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the generation and use of conformation-specific antibodies
WO2011143105A1 (en) * 2010-05-10 2011-11-17 Gilead Sciences, Inc. Bifunctional quinoline derivatives
US8367829B2 (en) 2010-05-10 2013-02-05 Gilead Sciences, Inc. Bi-functional pyrazolopyridine compounds
WO2012149334A2 (en) 2011-04-27 2012-11-01 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the generation and use of conformation-specific antibodies
WO2015063669A1 (en) 2013-10-30 2015-05-07 Wockhardt Limited Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof
US10433624B2 (en) * 2015-03-26 2019-10-08 Nike, Inc. Duffel bag
US11866482B2 (en) 2018-02-07 2024-01-09 Duke University System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791025A (fr) 1971-11-19 1973-05-07 Allen & Hanburys Ltd Composes heterocycliques
GB1457873A (en) 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
FR2390164A1 (fr) 1977-05-13 1978-12-08 Blanie Paul Association a action anti-asthmatique
US5602110A (en) 1994-08-31 1997-02-11 Case Western Reserve University Method and composition for treating cystic fibrosis
FR2753706B1 (fr) 1996-09-20 1998-10-30 Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant
FR2753969B1 (fr) 1996-09-27 1998-10-30 Adir Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ATE386531T1 (de) * 1997-02-28 2008-03-15 Nycomed Gmbh Synergistische kombination von pde-hemmern und adenylatcyclase-agonisten bzw. guanylcyclyse- agonisten
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
NZ527232A (en) * 1998-08-26 2005-03-24 Smithkline Beecham Corp A composition contaning a PDE 4 inhibitor and a beta adrenergic bronchodilator useful for treating pulmonary diseases

Also Published As

Publication number Publication date
BR9913152A (pt) 2001-05-15
AR022072A1 (es) 2002-09-04
IL141335A0 (en) 2002-03-10
JP2002523452A (ja) 2002-07-30
PE20001032A1 (es) 2000-11-10
NZ527232A (en) 2005-03-24
HUP0103160A3 (en) 2002-11-28
MY126544A (en) 2006-10-31
CA2341488A1 (en) 2000-03-09
NO20010882L (no) 2001-02-21
NO20010882D0 (no) 2001-02-21
US20010056122A1 (en) 2001-12-27
CN1314811A (zh) 2001-09-26
KR20010072931A (ko) 2001-07-31
US6555583B2 (en) 2003-04-29
TR200100500T2 (tr) 2001-06-21
EP1107747A4 (en) 2003-04-23
WO2000012078A1 (en) 2000-03-09
AU754379B2 (en) 2002-11-14
CZ293735B6 (cs) 2004-07-14
MA26302A1 (fr) 2004-10-01
EP1107747A1 (en) 2001-06-20
DZ2876A1 (fr) 2003-12-15
CZ2001692A3 (cs) 2002-02-13
AU5493999A (en) 2000-03-21
PL346271A1 (en) 2002-01-28
US6288118B1 (en) 2001-09-11

Similar Documents

Publication Publication Date Title
HUP0103160A2 (hu) Pulmonalis betegségek kezelésére alkalmas PDE4 inhibítort tartalmazó gyógyászati készítmények
NO20052690L (no) Fenylalaninderivater som dipeptidylpeptidaseinhibitorer for behandlingen eller profylaksen av sukkersyke.
EA200501805A1 (ru) Фармацевтическая композиция, содержащая ингибитор фермента дипептидилпептидазы
ATE395912T1 (de) Dipeptidylpeptidase-hemmer für die behandlung oder prävention von diabetes
ATE451369T1 (de) Piperidinopyrimidindipeptidylpeptidaseinhibitor n zur behandlung von diabetes
DE602004026440D1 (de) Kondensierte indole als dipeptidyl-peptidase-hemmer zur behandlung oder prävention von diabetes
NO20052380L (no) Beta-amino-heterosykliske dipeptidylpeptidaseinhibitorer for behandling og forhindring av diabetes
EP1796669A4 (en) AMINOPIPERIDINES AS DIPEPTIDYLPEPTIDASE IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
EP1651623A4 (en) HEXAHYDRODIAZEPINONES AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FOR THE TREATMENT OR PREVENTION OF DIABETES
EP1819674A4 (en) FUSIONED AMINOPIPERIDINES AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV FOR TREATING OR PREVENTING DIABETES
WO2007070434A3 (en) Fused aminopiperidines as dipeptidyl peptidase-4 inhibitors for the treatment or prevention of diabetes
EP1921917A4 (en) CONDENSED AMINOPIPERIDINES AS DIPEPTIDYLPEPTIDASE IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
AP1744A (en) Inhibitors of factor XA and other serine proteases involved in the coagulation cascade
WO2004112701A3 (en) Cyclohexylglycine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
DE60229530D1 (de) Substituierte piperazine als modulatoren des melanocortinrezeptors
NO20070049L (no) Pyrrolotriazinderivater anvendelig for behandling av hyperproliferative forstyrrelser og sykdommer assosiert med angiogenese
EP1784188A4 (en) DIPEPTIDYL-IV DIPEPTIDYL-IV INHIBITORY-CONTAINED TRIAZOLE DERIVATIVES FOR THE TREATMENT OR PREVENTION OF DIABETES
WO2004069162A3 (en) 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
WO2004064778A3 (en) 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
NO20045429L (no) Kombinasjon av organiske forbindelser
WO2004103276A3 (en) 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
WO2004050022A3 (en) Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
MY141528A (en) Anilinopyrazole derivatives useful for the treatment of diabetes
WO2003087062A3 (en) 4-(heterocyclyl)-benzenesulfoximine compounds for the treatment of inflammation
DE60329326D1 (de) Tace inhibitoren

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees