HUP0103160A2 - Pulmonalis betegségek kezelésére alkalmas PDE4 inhibítort tartalmazó gyógyászati készítmények - Google Patents
Pulmonalis betegségek kezelésére alkalmas PDE4 inhibítort tartalmazó gyógyászati készítményekInfo
- Publication number
- HUP0103160A2 HUP0103160A2 HU0103160A HUP0103160A HUP0103160A2 HU P0103160 A2 HUP0103160 A2 HU P0103160A2 HU 0103160 A HU0103160 A HU 0103160A HU P0103160 A HUP0103160 A HU P0103160A HU P0103160 A2 HUP0103160 A2 HU P0103160A2
- Authority
- HU
- Hungary
- Prior art keywords
- pulmonary diseases
- pharmaceutical compositions
- pde4 inhibitor
- treating pulmonary
- diseases containing
- Prior art date
Links
- 208000019693 Lung disease Diseases 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 title 1
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 title 1
- MSYGAHOHLUJIKV-UHFFFAOYSA-N 3,5-dimethyl-1-(3-nitrophenyl)-1h-pyrazole-4-carboxylic acid ethyl ester Chemical compound CC1=C(C(=O)OCC)C(C)=NN1C1=CC=CC([N+]([O-])=O)=C1 MSYGAHOHLUJIKV-UHFFFAOYSA-N 0.000 abstract 2
- 102000011017 Type 4 Cyclic Nucleotide Phosphodiesterases Human genes 0.000 abstract 2
- 108010037584 Type 4 Cyclic Nucleotide Phosphodiesterases Proteins 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A találmány pulmonalis betegségek tüneteinek kezelésére vagycsökkentésére, illetve a pulmonalis betegségek súlyosságánakkezelésére vagy csökkentésére szolgáló gyógyszerészeti kompozíciókravonatkozik. Közelebbről a találmány foszfodiészteráz-4 (PDE4) általmediált pulmonalis betegségek kezelésére szolgáló kompozíciókravonatkozik. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9797398P | 1998-08-26 | 1998-08-26 | |
PCT/US1999/019332 WO2000012078A1 (en) | 1998-08-26 | 1999-08-24 | Therapies for treating pulmonary diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0103160A2 true HUP0103160A2 (hu) | 2002-01-28 |
HUP0103160A3 HUP0103160A3 (en) | 2002-11-28 |
Family
ID=22266001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0103160A HUP0103160A3 (en) | 1998-08-26 | 1999-08-24 | Pharmaceutical compositions for treating pulmonary diseases containing pde4 inhibitor |
Country Status (21)
Country | Link |
---|---|
US (2) | US6288118B1 (hu) |
EP (1) | EP1107747A4 (hu) |
JP (1) | JP2002523452A (hu) |
KR (1) | KR20010072931A (hu) |
CN (1) | CN1314811A (hu) |
AR (1) | AR022072A1 (hu) |
AU (1) | AU754379B2 (hu) |
BR (1) | BR9913152A (hu) |
CA (1) | CA2341488A1 (hu) |
CZ (1) | CZ293735B6 (hu) |
DZ (1) | DZ2876A1 (hu) |
HU (1) | HUP0103160A3 (hu) |
IL (1) | IL141335A0 (hu) |
MA (1) | MA26302A1 (hu) |
MY (1) | MY126544A (hu) |
NO (1) | NO20010882D0 (hu) |
NZ (1) | NZ527232A (hu) |
PE (1) | PE20001032A1 (hu) |
PL (1) | PL346271A1 (hu) |
TR (1) | TR200100500T2 (hu) |
WO (1) | WO2000012078A1 (hu) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
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US6525018B1 (en) * | 1999-05-17 | 2003-02-25 | The General Hospital Corp. | Treating eye disorders using intestinal trefoil proteins |
US6624181B1 (en) | 1997-02-28 | 2003-09-23 | Altana Pharma Ag | Synergistic combination |
US20030186882A1 (en) * | 2001-07-31 | 2003-10-02 | Podolsky Daniel K. | Methods and compositions for treating and preventing distal bowel lesions |
US20030185838A1 (en) * | 2001-11-28 | 2003-10-02 | Podolsky Daniel K. | Methods and compositions for treating lesions of the respiratory epithelium |
NZ527232A (en) * | 1998-08-26 | 2005-03-24 | Smithkline Beecham Corp | A composition contaning a PDE 4 inhibitor and a beta adrenergic bronchodilator useful for treating pulmonary diseases |
US8933032B2 (en) | 1998-10-20 | 2015-01-13 | Children's Hospital Medical Center | Surfactant protein D for the treatment of disorders associated with lung injury |
EP2193808A1 (en) * | 1999-08-21 | 2010-06-09 | Nycomed GmbH | Synergistic combination |
SK17052002A3 (sk) | 2000-06-05 | 2003-12-02 | Altana Pharma Ag | Pyridazinónové zlúčeniny, farmaceutický prostriedok s ich obsahom a ich použitie |
US20040171544A1 (en) * | 2001-04-24 | 2004-09-02 | Barker Nicholas P. | Trefoil domain-containing polypeptides and uses thereof |
US20030105016A1 (en) * | 2001-09-06 | 2003-06-05 | Podolsky Daniel K. | Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions |
US7538082B2 (en) | 2001-04-24 | 2009-05-26 | The General Hospital Corporation | Methods and compositions for treating oral and esophageal lesions |
US20060189526A1 (en) * | 2002-04-24 | 2006-08-24 | Podolsky Daniel K | Compositions containing an intestinal trefoil peptide and a mucoadhesive |
US20030181384A1 (en) * | 2001-09-06 | 2003-09-25 | Podolsky Daniel K. | Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions |
US20030185839A1 (en) * | 2001-10-05 | 2003-10-02 | Podolsky Daniel K. | Methods and compositions for treating dermal lesions |
MXPA04003267A (es) * | 2001-10-05 | 2004-07-08 | Gen Hospital Corp | Metodos y composiciones para tratar lesiones dermicas. |
US7931022B2 (en) * | 2001-10-19 | 2011-04-26 | Respirks, Inc. | Method and apparatus for dispensing inhalator medicament |
JP2005532988A (ja) * | 2001-11-28 | 2005-11-04 | ザ ジェネラル ホスピタル コーポレーション | 呼吸上皮の病変を治療するための方法および組成物 |
GB0129395D0 (en) * | 2001-12-07 | 2002-01-30 | Pfizer Ltd | Pharmaceutical combination |
MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
CN1655675A (zh) * | 2002-03-26 | 2005-08-17 | 综合医院公司 | 利用三叶肽的联合治疗 |
NZ536918A (en) * | 2002-05-07 | 2006-09-29 | Altana Pharma Ag | Combination of pantoprazole and a respiratory agent for the treatment of respiratory diseases |
MXPA04011018A (es) * | 2002-05-07 | 2005-01-25 | Altana Pharma Ag | Nueva combinacion de inhibidores reversibles de la bomba de protones y productos terapueticos para tratar trastornos de las vias respiratorias. |
DE10220458A1 (de) * | 2002-05-07 | 2003-11-27 | Altana Pharma Ag | Kombination zur Behandlung von Atemwegserkrankungen |
DE10220459A1 (de) * | 2002-05-07 | 2003-11-27 | Byk Gulden Lomberg Chem Fab | Neue Kombination zur Behandlung von Atemwegserkrankungen |
US20060188471A1 (en) * | 2002-10-31 | 2006-08-24 | Podolsky Daniel K | Methods of treating epithelial lesions |
MXPA05005438A (es) * | 2002-11-27 | 2005-08-03 | Altana Pharma Ag | Combinacion sinergica que comprende roflumilast y (r, r) -formoterol. |
RS51081B (sr) * | 2002-11-27 | 2010-10-31 | Nycomed Gmbh. | Nova sinergistička kombinacija koja uključuje roflumilast i formoterol |
KR101179012B1 (ko) | 2003-03-10 | 2012-09-03 | 니코메드 게엠베하 | 로플루미라스트 신규한 제조 방법 |
WO2004087151A1 (ja) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co., Ltd. | 医薬組成物 |
SE527200C2 (sv) * | 2003-06-19 | 2006-01-17 | Microdrug Ag | Inhalatoranordning samt kombinerade doser av formaterol och fluticason |
WO2005123072A1 (en) * | 2004-06-14 | 2005-12-29 | Sepracor Inc. | Methods and compositions for the treatment of pulmonary diseases |
US20090035224A1 (en) * | 2004-06-14 | 2009-02-05 | Sepracor Inc. | Methods of Using Albuterol and Calcium Activated Potassium Channel Openers |
AU2006224619B2 (en) | 2005-03-16 | 2012-06-07 | Takeda Gmbh | Taste masked dosage form containing roflumilast |
DE102005030733A1 (de) * | 2005-07-01 | 2007-01-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff |
US20090182035A1 (en) * | 2007-04-11 | 2009-07-16 | Alcon Research, Ltd. | Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis |
CA2682730A1 (en) * | 2007-04-11 | 2008-10-23 | Alcon Research, Ltd. | Use of an inhibitor of tnf.alpha. plus an antihistamine to treat allergic rhinitis and allergic conjunctivitis |
CN107243076A (zh) * | 2009-04-22 | 2017-10-13 | 印第安那大学科技研究公司 | 用于治疗慢性阻塞性肺病和哮喘的组合物和方法 |
RU2012117141A (ru) * | 2009-10-01 | 2013-11-10 | Алькон Рисерч, Лтд. | Композиции олопатадина и способы их применения |
KR101035488B1 (ko) * | 2009-10-05 | 2011-05-20 | 숭실대학교산학협력단 | 자동차 블랙박스 영상물 수집 방법 |
US8771693B2 (en) | 2009-10-27 | 2014-07-08 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the generation and use of conformation-specific antibodies |
WO2011143105A1 (en) * | 2010-05-10 | 2011-11-17 | Gilead Sciences, Inc. | Bifunctional quinoline derivatives |
US8367829B2 (en) | 2010-05-10 | 2013-02-05 | Gilead Sciences, Inc. | Bi-functional pyrazolopyridine compounds |
WO2012149334A2 (en) | 2011-04-27 | 2012-11-01 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the generation and use of conformation-specific antibodies |
WO2015063669A1 (en) | 2013-10-30 | 2015-05-07 | Wockhardt Limited | Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof |
US10433624B2 (en) * | 2015-03-26 | 2019-10-08 | Nike, Inc. | Duffel bag |
US11866482B2 (en) | 2018-02-07 | 2024-01-09 | Duke University | System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE791025A (fr) | 1971-11-19 | 1973-05-07 | Allen & Hanburys Ltd | Composes heterocycliques |
GB1457873A (en) | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
FR2390164A1 (fr) | 1977-05-13 | 1978-12-08 | Blanie Paul | Association a action anti-asthmatique |
US5602110A (en) | 1994-08-31 | 1997-02-11 | Case Western Reserve University | Method and composition for treating cystic fibrosis |
FR2753706B1 (fr) | 1996-09-20 | 1998-10-30 | Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant | |
FR2753969B1 (fr) | 1996-09-27 | 1998-10-30 | Adir | Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
ATE386531T1 (de) * | 1997-02-28 | 2008-03-15 | Nycomed Gmbh | Synergistische kombination von pde-hemmern und adenylatcyclase-agonisten bzw. guanylcyclyse- agonisten |
US5858694A (en) * | 1997-05-30 | 1999-01-12 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of cancerous lesions |
NZ527232A (en) * | 1998-08-26 | 2005-03-24 | Smithkline Beecham Corp | A composition contaning a PDE 4 inhibitor and a beta adrenergic bronchodilator useful for treating pulmonary diseases |
-
1999
- 1999-08-24 NZ NZ527232A patent/NZ527232A/en unknown
- 1999-08-24 CA CA002341488A patent/CA2341488A1/en not_active Abandoned
- 1999-08-24 CZ CZ2001692A patent/CZ293735B6/cs not_active IP Right Cessation
- 1999-08-24 WO PCT/US1999/019332 patent/WO2000012078A1/en not_active Application Discontinuation
- 1999-08-24 US US09/763,516 patent/US6288118B1/en not_active Expired - Fee Related
- 1999-08-24 CN CN99810111A patent/CN1314811A/zh active Pending
- 1999-08-24 DZ DZ990176A patent/DZ2876A1/xx active
- 1999-08-24 EP EP99941248A patent/EP1107747A4/en not_active Withdrawn
- 1999-08-24 PL PL99346271A patent/PL346271A1/xx unknown
- 1999-08-24 IL IL14133599A patent/IL141335A0/xx unknown
- 1999-08-24 JP JP2000567196A patent/JP2002523452A/ja active Pending
- 1999-08-24 HU HU0103160A patent/HUP0103160A3/hu unknown
- 1999-08-24 AU AU54939/99A patent/AU754379B2/en not_active Ceased
- 1999-08-24 BR BR9913152-8A patent/BR9913152A/pt not_active IP Right Cessation
- 1999-08-24 MY MYPI99003615A patent/MY126544A/en unknown
- 1999-08-24 KR KR1020017002358A patent/KR20010072931A/ko not_active Application Discontinuation
- 1999-08-24 TR TR2001/00500T patent/TR200100500T2/xx unknown
- 1999-08-25 PE PE1999000856A patent/PE20001032A1/es not_active Application Discontinuation
- 1999-08-25 MA MA25745A patent/MA26302A1/fr unknown
- 1999-09-03 AR ARP990104234A patent/AR022072A1/es not_active Application Discontinuation
-
2001
- 2001-02-21 NO NO20010882A patent/NO20010882D0/no not_active Application Discontinuation
- 2001-08-20 US US09/933,455 patent/US6555583B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
BR9913152A (pt) | 2001-05-15 |
AR022072A1 (es) | 2002-09-04 |
IL141335A0 (en) | 2002-03-10 |
JP2002523452A (ja) | 2002-07-30 |
PE20001032A1 (es) | 2000-11-10 |
NZ527232A (en) | 2005-03-24 |
HUP0103160A3 (en) | 2002-11-28 |
MY126544A (en) | 2006-10-31 |
CA2341488A1 (en) | 2000-03-09 |
NO20010882L (no) | 2001-02-21 |
NO20010882D0 (no) | 2001-02-21 |
US20010056122A1 (en) | 2001-12-27 |
CN1314811A (zh) | 2001-09-26 |
KR20010072931A (ko) | 2001-07-31 |
US6555583B2 (en) | 2003-04-29 |
TR200100500T2 (tr) | 2001-06-21 |
EP1107747A4 (en) | 2003-04-23 |
WO2000012078A1 (en) | 2000-03-09 |
AU754379B2 (en) | 2002-11-14 |
CZ293735B6 (cs) | 2004-07-14 |
MA26302A1 (fr) | 2004-10-01 |
EP1107747A1 (en) | 2001-06-20 |
DZ2876A1 (fr) | 2003-12-15 |
CZ2001692A3 (cs) | 2002-02-13 |
AU5493999A (en) | 2000-03-21 |
PL346271A1 (en) | 2002-01-28 |
US6288118B1 (en) | 2001-09-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |