HUP0102929A2 - Levozimendan alkalmazása pulmonáris hipertenzió kezelésére alkalmas gyógyszerkészítmény előállítására - Google Patents
Levozimendan alkalmazása pulmonáris hipertenzió kezelésére alkalmas gyógyszerkészítmény előállításáraInfo
- Publication number
- HUP0102929A2 HUP0102929A2 HU0102929A HUP0102929A HUP0102929A2 HU P0102929 A2 HUP0102929 A2 HU P0102929A2 HU 0102929 A HU0102929 A HU 0102929A HU P0102929 A HUP0102929 A HU P0102929A HU P0102929 A2 HUP0102929 A2 HU P0102929A2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- pulmonary hypertension
- levosimendan
- medicament
- manufacture
- Prior art date
Links
- 208000002815 pulmonary hypertension Diseases 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- WHXMKTBCFHIYNQ-SECBINFHSA-N levosimendan Chemical compound C[C@@H]1CC(=O)NN=C1C1=CC=C(NN=C(C#N)C#N)C=C1 WHXMKTBCFHIYNQ-SECBINFHSA-N 0.000 title 1
- 229960000692 levosimendan Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)-phenyl]-hydrazino]-propanenitrile Chemical compound 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Abstract
A tal lm ny t rgya (-)-[[4-(1,4,5,6-tetrahidro-4-metil-6-oxo-3-piridazinil)-fenil]-hidrazino]-prop ndinitril vagy gyógyszerészetilegelfogadható sója alkalmaz sa pulmon ris hipertenzió kezelésérealkalmas gyógyszerkészítmény elő llít s ra. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI981473A FI981473A (fi) | 1998-06-25 | 1998-06-25 | Menetelmä pulmonaalihypertension hoitamiseksi |
PCT/FI1999/000540 WO1999066912A2 (en) | 1998-06-25 | 1999-06-18 | Method of treating pulmonary hypertension |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0102929A2 true HUP0102929A2 (hu) | 2002-04-29 |
HUP0102929A3 HUP0102929A3 (en) | 2002-07-29 |
HU226021B1 HU226021B1 (en) | 2008-03-28 |
Family
ID=8552079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0102929A HU226021B1 (en) | 1998-06-25 | 1999-06-18 | Use of levosimendan in the manufacture of a medicament for the treatment of pulmonary hypertension |
Country Status (24)
Country | Link |
---|---|
US (1) | US6462045B1 (hu) |
EP (1) | EP1089737B1 (hu) |
JP (1) | JP4536922B2 (hu) |
KR (1) | KR100661769B1 (hu) |
AT (1) | ATE226076T1 (hu) |
AU (1) | AU748883B2 (hu) |
BR (1) | BR9911422A (hu) |
CA (1) | CA2335280C (hu) |
CZ (1) | CZ300844B6 (hu) |
DE (1) | DE69903546T2 (hu) |
DK (1) | DK1089737T3 (hu) |
EA (1) | EA003055B1 (hu) |
EE (1) | EE04355B1 (hu) |
ES (1) | ES2186375T3 (hu) |
FI (1) | FI981473A (hu) |
HU (1) | HU226021B1 (hu) |
MX (1) | MXPA00012618A (hu) |
NO (1) | NO317593B1 (hu) |
NZ (1) | NZ508833A (hu) |
PL (1) | PL193055B1 (hu) |
PT (1) | PT1089737E (hu) |
SK (1) | SK284581B6 (hu) |
WO (1) | WO1999066912A2 (hu) |
ZA (1) | ZA200007462B (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI20001542A (fi) * | 2000-06-29 | 2001-12-30 | Orion Yhtymae Oyj | Menetelmä septisen sokin hoitamiseksi |
FI20002755A0 (fi) | 2000-12-15 | 2000-12-15 | Orion Yhtymae Oyj | Menetelmä erektiilin dysfunktion hoitamiseen |
FI20010233A0 (fi) | 2001-02-08 | 2001-02-08 | Orion Corp | Menetelmä sydämen vajaatoiminnan hoitoon |
FI20040675A0 (fi) * | 2004-05-12 | 2004-05-12 | Orion Corp | Menetelmä sydämen hypertrofian hoitoon ja estoon |
WO2006087420A2 (en) * | 2005-02-18 | 2006-08-24 | Orion Corporation | A method for treating heart failure |
CA3161960A1 (en) | 2019-12-16 | 2021-06-24 | Tenax Therapeutics, Inc. | Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (ph-hfpef) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0302595B1 (en) * | 1987-07-07 | 1994-02-02 | Beecham Group Plc | Pinacidil for treatment of pulmonary hypertension or right heart failure |
GB2251615B (en) * | 1991-01-03 | 1995-02-08 | Orion Yhtymae Oy | (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile |
RO113612B1 (ro) * | 1991-04-17 | 1998-09-30 | Merck & Co Inc | Compozitie oftalmica |
GB2266841A (en) | 1992-05-06 | 1993-11-17 | Orion Yhtymae Oy | Compounds for use as anti-ischemic medicaments |
GB9614098D0 (en) * | 1996-07-05 | 1996-09-04 | Orion Yhtymae Oy | Transdermal delivery of levosimendan |
-
1998
- 1998-06-25 FI FI981473A patent/FI981473A/fi unknown
-
1999
- 1999-06-18 SK SK1925-2000A patent/SK284581B6/sk not_active IP Right Cessation
- 1999-06-18 US US09/720,198 patent/US6462045B1/en not_active Expired - Lifetime
- 1999-06-18 AT AT99931313T patent/ATE226076T1/de active
- 1999-06-18 BR BR9911422-4A patent/BR9911422A/pt not_active Application Discontinuation
- 1999-06-18 EP EP99931313A patent/EP1089737B1/en not_active Expired - Lifetime
- 1999-06-18 DE DE69903546T patent/DE69903546T2/de not_active Expired - Lifetime
- 1999-06-18 MX MXPA00012618A patent/MXPA00012618A/es not_active IP Right Cessation
- 1999-06-18 EA EA200100074A patent/EA003055B1/ru not_active IP Right Cessation
- 1999-06-18 PT PT99931313T patent/PT1089737E/pt unknown
- 1999-06-18 HU HU0102929A patent/HU226021B1/hu not_active IP Right Cessation
- 1999-06-18 CA CA002335280A patent/CA2335280C/en not_active Expired - Fee Related
- 1999-06-18 JP JP2000555598A patent/JP4536922B2/ja not_active Expired - Fee Related
- 1999-06-18 AU AU47864/99A patent/AU748883B2/en not_active Ceased
- 1999-06-18 NZ NZ508833A patent/NZ508833A/xx not_active IP Right Cessation
- 1999-06-18 DK DK99931313T patent/DK1089737T3/da active
- 1999-06-18 PL PL345467A patent/PL193055B1/pl not_active IP Right Cessation
- 1999-06-18 EE EEP200000775A patent/EE04355B1/xx not_active IP Right Cessation
- 1999-06-18 WO PCT/FI1999/000540 patent/WO1999066912A2/en active IP Right Grant
- 1999-06-18 KR KR1020007014765A patent/KR100661769B1/ko not_active IP Right Cessation
- 1999-06-18 ES ES99931313T patent/ES2186375T3/es not_active Expired - Lifetime
- 1999-06-18 CZ CZ20004663A patent/CZ300844B6/cs not_active IP Right Cessation
-
2000
- 2000-12-13 ZA ZA200007462A patent/ZA200007462B/en unknown
- 2000-12-22 NO NO20006652A patent/NO317593B1/no not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69201640D1 (de) | (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-hydrazono]propandinitril. | |
NO952309D0 (no) | Anvendelse av riluzol ved behandling av Parkinsons sykdom og Parkinsonske syndromer | |
IL165264A (en) | Protein kinase inhibitors, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for treating protein kinase-associated diseases | |
TW237452B (hu) | ||
WO2002000209A3 (en) | Gabapentin analogues for sleep disorders | |
MX9701329A (es) | Metodos para la inhibicion de la replicacion viral. | |
ATE196086T1 (de) | Anti-ischaemisches arzneimittel | |
CY1107616T1 (el) | Καινοτομος χρηση της 2-[5-(4-φθοροφαινυλο)-3-πυριδυλομεθυλαμινομεθυλο]-χρωμανης και των φυσιολογικα αποδεκτων αλατων της | |
HUP0102929A2 (hu) | Levozimendan alkalmazása pulmonáris hipertenzió kezelésére alkalmas gyógyszerkészítmény előállítására | |
NO981856L (no) | Anvendelse av 1-(2-naft-2-yletyl)-4-(3-trifluormetylfenyl)-1,2,3,6-tetrahydropyridin for fremstilling av legemidler for behandling av amyotrof lateral sclerose | |
NO994257D0 (no) | Anvendelse av levobupivakain ved ansiktskirurgi | |
HUP0300298A2 (hu) | 4-[Piperazinil-8-(kinolinil-metil)]benzamid-származékok, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények | |
NZ513851A (en) | Use of saredutant and the pharmaceutically acceptable salts thereof to produce medicaments used to treat or prevent mood disorders, adjustment disorders or mixed anxiety-depression disorders | |
HUP0300863A2 (hu) | N-(3,5-diklór-2-metoxi-fenil)-4-metoxi-3-(1-piperazinil)-benzolszulfonamid, eljárás elżállítására és a vegyületet tartalmazó gyógyszerkészítmény | |
FI956269A (fi) | Ropivakaiinin käyttö kipua lievittävän vaikutuksen omaavan ja häviävän vähäisen motoriikan estymisen aikaansaavan farmaseuttisen tuotteen valmistukseen | |
BR0109119A (pt) | Uso de (r)-(-)-2-[5-(4-fluorofenil)-3-piridilmetil-aminometil]-cr omano e seus sais fisiologicamente aceitáveis | |
HUP0402654A2 (hu) | 2-[(2'-Halogén-3',5'-dialkoxi-fenil)-imino]-imidazolidin-származékok, alkalmazásuk és az ezeket tartalmazó gyógyszerkészítmények | |
HUP0203161A2 (hu) | Benzamidinszármazékok, eljárás az előállításukra, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk | |
NZ543709A (en) | Use of tyrosine kinase inhibitor to treat diabetes | |
AU7928700A (en) | A new use of levosimendan | |
NO20010984D0 (no) | Anvendelse av R(+)-<alfa>-(2,3-dimetoksyfenyl)-1-[2-(4- fluorfenyl)etyl]-4-piperidinmetanol for behandling av søvnforstyrrelser | |
NO974840L (no) | Ny form av (E)-3-[6-[[(2,6-diklorfenyl)-tio]metyl]-3-(2-fenyletoksy)-2-pyridinyl]-2-propensyre |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC9A | Change of name, address |
Owner name: ORION CORPORATION ID NO.1999212-6, FI Free format text: FORMER OWNER(S): ORION CORP., FI |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |