HUP0102412A2 - 2"-Dezoxi-higromicin-származékok - Google Patents

2"-Dezoxi-higromicin-származékok

Info

Publication number
HUP0102412A2
HUP0102412A2 HU0102412A HUP0102412A HUP0102412A2 HU P0102412 A2 HUP0102412 A2 HU P0102412A2 HU 0102412 A HU0102412 A HU 0102412A HU P0102412 A HUP0102412 A HU P0102412A HU P0102412 A2 HUP0102412 A2 HU P0102412A2
Authority
HU
Hungary
Prior art keywords
compounds
general formula
derivatives
relates
protozoal infections
Prior art date
Application number
HU0102412A
Other languages
English (en)
Inventor
Robert Gerald II. Linde
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of HUP0102412A2 publication Critical patent/HUP0102412A2/hu
Publication of HUP0102412A3 publication Critical patent/HUP0102412A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

(57) A találmány tárgya 2<-dezoxi-higromicin-származékok. A találmány(1) általános képletű vegyületekre és gyógyászatilag elfogadhatósóira, prodrugjaira és szolvátjaira vonatkozik, ahol R1 és R2jelentése a leírásban megadott. Az (1) általános képletű vegyületekantibakteriális és antiprotozoális szerek, melyeket különbözőbakteriális és protozoális fertőzések és az ezekkel kapcsolatosrendellenességek kezelésére lehet használni. A találmány kiterjed az(1) általános képletű vegyületeket tartalmazó gyógyászatikészítményekre és a vegyületek alkalmazására bakteriális ésprotozoális fertőzések kezelésére alkalmas gyógyszerek előállításárais. Ó
HU0102412A 1998-05-04 1999-04-08 2"-deoxy hygromycin derivatives HUP0102412A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8405898P 1998-05-04 1998-05-04
PCT/IB1999/000611 WO1999057127A1 (en) 1998-05-04 1999-04-08 2'-deoxy hygromycin derivatives

Publications (2)

Publication Number Publication Date
HUP0102412A2 true HUP0102412A2 (hu) 2001-11-28
HUP0102412A3 HUP0102412A3 (en) 2003-07-28

Family

ID=22182624

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102412A HUP0102412A3 (en) 1998-05-04 1999-04-08 2"-deoxy hygromycin derivatives

Country Status (38)

Country Link
US (1) US6342497B1 (hu)
EP (1) EP1077984B1 (hu)
JP (1) JP2002513798A (hu)
KR (1) KR100396099B1 (hu)
CN (1) CN1299367A (hu)
AP (1) AP1069A (hu)
AR (1) AR015776A1 (hu)
AT (1) ATE243218T1 (hu)
AU (1) AU762302B2 (hu)
BG (1) BG104995A (hu)
BR (1) BR9910232A (hu)
CA (1) CA2331261C (hu)
DE (1) DE69908936T2 (hu)
DK (1) DK1077984T3 (hu)
DZ (1) DZ2779A1 (hu)
EA (1) EA004374B1 (hu)
ES (1) ES2199559T3 (hu)
GT (1) GT199900058A (hu)
HN (1) HN1999000064A (hu)
HR (1) HRP20000748A2 (hu)
HU (1) HUP0102412A3 (hu)
ID (1) ID26368A (hu)
IL (1) IL139020A0 (hu)
IS (1) IS5680A (hu)
MA (1) MA26626A1 (hu)
NO (1) NO20005551L (hu)
NZ (1) NZ507450A (hu)
OA (1) OA11507A (hu)
PA (1) PA8471901A1 (hu)
PE (1) PE20000440A1 (hu)
PL (1) PL344085A1 (hu)
PT (1) PT1077984E (hu)
SK (1) SK16442000A3 (hu)
TN (1) TNSN99084A1 (hu)
TR (1) TR200003249T2 (hu)
WO (1) WO1999057127A1 (hu)
YU (1) YU64300A (hu)
ZA (1) ZA993063B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0104949A3 (en) * 1998-12-02 2003-12-29 Pfizer Prod Inc Hygromycin a derivatives as antibacterial agents process for preparing them and pharmaceutical compositions comprising them
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
PL359179A1 (en) 2000-06-02 2004-08-23 Pfizer Products Inc. Hygromycin a derivatives for the treatment of bacterial and protozoal infections
CN102168034B (zh) * 2010-11-29 2012-12-05 中国科学院南海海洋研究所 一种海洋链霉菌以及利用该菌制备替达霉素a和b的方法
EP3840743A4 (en) * 2018-08-20 2022-08-17 Northeastern University HYGROMYCIN A COMPOUNDS AND METHODS OF TREATING SPIROCHETE DISEASES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2832356B2 (ja) * 1988-03-31 1998-12-09 武田薬品工業株式会社 ハイグロマイシン類の合成中間体および製造法

Also Published As

Publication number Publication date
YU64300A (sh) 2003-07-07
AP9901525A0 (en) 1999-06-30
EP1077984A1 (en) 2001-02-28
OA11507A (en) 2004-05-13
DK1077984T3 (da) 2003-09-15
NO20005551L (no) 2001-01-02
BG104995A (bg) 2001-07-31
PL344085A1 (en) 2001-09-24
GT199900058A (es) 2000-10-07
KR20010043267A (ko) 2001-05-25
PT1077984E (pt) 2003-09-30
HN1999000064A (es) 2000-01-12
ES2199559T3 (es) 2004-02-16
SK16442000A3 (sk) 2001-07-10
KR100396099B1 (ko) 2003-08-27
WO1999057127A1 (en) 1999-11-11
HRP20000748A2 (en) 2001-06-30
TR200003249T2 (tr) 2001-03-21
DZ2779A1 (fr) 2005-04-23
AU2850899A (en) 1999-11-23
AR015776A1 (es) 2001-05-16
DE69908936D1 (en) 2003-07-24
IS5680A (is) 2000-10-24
PE20000440A1 (es) 2000-05-26
US6342497B1 (en) 2002-01-29
AU762302B2 (en) 2003-06-19
TNSN99084A1 (fr) 2005-11-10
DE69908936T2 (de) 2004-05-19
NO20005551D0 (no) 2000-11-03
EA200001028A1 (ru) 2001-04-23
CA2331261A1 (en) 1999-11-11
NZ507450A (en) 2003-08-29
ID26368A (id) 2000-12-14
IL139020A0 (en) 2001-11-25
HUP0102412A3 (en) 2003-07-28
JP2002513798A (ja) 2002-05-14
CN1299367A (zh) 2001-06-13
PA8471901A1 (es) 2000-09-29
CA2331261C (en) 2004-07-27
ZA993063B (en) 2000-11-03
BR9910232A (pt) 2001-01-09
MA26626A1 (fr) 2004-12-20
EA004374B1 (ru) 2004-04-29
ATE243218T1 (de) 2003-07-15
EP1077984B1 (en) 2003-06-18
AP1069A (en) 2002-05-14

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