HUP0101355A3 - Genomic sequences upstream of the coding region of the g-csf gene for protein production and delivery - Google Patents
Genomic sequences upstream of the coding region of the g-csf gene for protein production and deliveryInfo
- Publication number
- HUP0101355A3 HUP0101355A3 HU0101355A HUP0101355A HUP0101355A3 HU P0101355 A3 HUP0101355 A3 HU P0101355A3 HU 0101355 A HU0101355 A HU 0101355A HU P0101355 A HUP0101355 A HU P0101355A HU P0101355 A3 HUP0101355 A3 HU P0101355A3
- Authority
- HU
- Hungary
- Prior art keywords
- delivery
- coding region
- protein production
- genomic sequences
- sequences upstream
- Prior art date
Links
- 108091026890 Coding region Proteins 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000014616 translation Effects 0.000 title 1
- 238000011144 upstream manufacturing Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8464998P | 1998-05-07 | 1998-05-07 | |
| PCT/US1999/009924 WO1999057291A1 (en) | 1998-05-07 | 1999-05-05 | Genomic sequences upstream of the coding region of the g-csf gene for protein production and delivery |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0101355A2 HUP0101355A2 (hu) | 2001-08-28 |
| HUP0101355A3 true HUP0101355A3 (en) | 2003-08-28 |
Family
ID=22186313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0101355A HUP0101355A3 (en) | 1998-05-07 | 1999-05-05 | Genomic sequences upstream of the coding region of the g-csf gene for protein production and delivery |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US6242218B1 (hu) |
| EP (1) | EP1075530A1 (hu) |
| JP (1) | JP2002513579A (hu) |
| KR (1) | KR20010071207A (hu) |
| CN (1) | CN1308680A (hu) |
| AR (1) | AR016263A1 (hu) |
| AU (1) | AU762969B2 (hu) |
| CA (1) | CA2328476A1 (hu) |
| CZ (1) | CZ299460B6 (hu) |
| GC (1) | GC0000172A (hu) |
| HU (1) | HUP0101355A3 (hu) |
| IL (1) | IL139431A0 (hu) |
| NO (1) | NO20005586L (hu) |
| NZ (1) | NZ507451A (hu) |
| PL (1) | PL344391A1 (hu) |
| TR (1) | TR200003272T2 (hu) |
| WO (1) | WO1999057291A1 (hu) |
| ZA (1) | ZA200005744B (hu) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001042442A2 (en) | 1999-12-10 | 2001-06-14 | Cytos Biotechnology Ag | Activation of endogenous genes by genomic introduction of a replicon |
| JP2002017357A (ja) * | 2000-07-04 | 2002-01-22 | Calpis Co Ltd | アンカーペプチド、融合蛋白質、及び蛋白質の固定化方法 |
| US20030082511A1 (en) * | 2001-09-25 | 2003-05-01 | Brown Steven J. | Identification of modulatory molecules using inducible promoters |
| JP5570677B2 (ja) | 2002-04-25 | 2014-08-13 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | α−ガラクトシダーゼＡ欠損症の治療 |
| JP4896745B2 (ja) * | 2004-02-02 | 2012-03-14 | アンブレツクス・インコーポレイテツド | 修飾されたヒトインターフェロンポリペプチドおよびこれらの使用 |
| JP2010524467A (ja) | 2007-04-16 | 2010-07-22 | モメンタ ファーマシューティカルズ インコーポレイテッド | 規定の糖タンパク質産物および関連の方法 |
| WO2008137471A2 (en) | 2007-05-02 | 2008-11-13 | Ambrx, Inc. | Modified interferon beta polypeptides and their uses |
| CA2712606A1 (en) | 2008-02-08 | 2009-08-13 | Ambrx, Inc. | Modified leptin polypeptides and their uses |
| JP2011518555A (ja) * | 2008-04-14 | 2011-06-30 | サンガモ バイオサイエンシーズ， インコーポレイテッド | 標的組込みのための線形ドナーコンストラクト |
| NZ600382A (en) | 2008-07-23 | 2013-11-29 | Ambrx Inc | Modified bovine G-CSF polypeptides and their uses |
| TWI480288B (zh) | 2010-09-23 | 2015-04-11 | Lilly Co Eli | 牛顆粒細胞群落刺激因子及其變體之調配物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641670A (en) * | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
| US5968502A (en) | 1991-11-05 | 1999-10-19 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
-
1999
- 1999-05-05 CN CN99808187A patent/CN1308680A/zh active Pending
- 1999-05-05 EP EP99920374A patent/EP1075530A1/en not_active Withdrawn
- 1999-05-05 NZ NZ507451A patent/NZ507451A/en unknown
- 1999-05-05 TR TR2000/03272T patent/TR200003272T2/xx unknown
- 1999-05-05 US US09/305,384 patent/US6242218B1/en not_active Expired - Fee Related
- 1999-05-05 CZ CZ20003807A patent/CZ299460B6/cs not_active IP Right Cessation
- 1999-05-05 AU AU37887/99A patent/AU762969B2/en not_active Ceased
- 1999-05-05 IL IL13943199A patent/IL139431A0/xx unknown
- 1999-05-05 HU HU0101355A patent/HUP0101355A3/hu unknown
- 1999-05-05 CA CA002328476A patent/CA2328476A1/en not_active Abandoned
- 1999-05-05 WO PCT/US1999/009924 patent/WO1999057291A1/en not_active Application Discontinuation
- 1999-05-05 PL PL99344391A patent/PL344391A1/xx not_active Application Discontinuation
- 1999-05-05 KR KR1020007012303A patent/KR20010071207A/ko not_active Application Discontinuation
- 1999-05-05 JP JP2000547245A patent/JP2002513579A/ja active Pending
- 1999-05-06 AR ARP990102132A patent/AR016263A1/es not_active Application Discontinuation
- 1999-05-08 GC GCP1999147 patent/GC0000172A/en active
-
2000
- 2000-10-17 ZA ZA200005744A patent/ZA200005744B/en unknown
- 2000-11-06 NO NO20005586A patent/NO20005586L/no not_active Application Discontinuation
-
2001
- 2001-04-27 US US09/845,020 patent/US20030022850A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AR016263A1 (es) | 2001-06-20 |
| CN1308680A (zh) | 2001-08-15 |
| IL139431A0 (en) | 2001-11-25 |
| AU762969B2 (en) | 2003-07-10 |
| US6242218B1 (en) | 2001-06-05 |
| CZ20003807A3 (cs) | 2001-04-11 |
| HUP0101355A2 (hu) | 2001-08-28 |
| WO1999057291A1 (en) | 1999-11-11 |
| CZ299460B6 (cs) | 2008-08-06 |
| NZ507451A (en) | 2003-12-19 |
| ZA200005744B (en) | 2001-05-16 |
| CA2328476A1 (en) | 1999-11-11 |
| TR200003272T2 (tr) | 2001-03-21 |
| EP1075530A1 (en) | 2001-02-14 |
| AU3788799A (en) | 1999-11-23 |
| KR20010071207A (ko) | 2001-07-28 |
| NO20005586D0 (no) | 2000-11-06 |
| PL344391A1 (en) | 2001-11-05 |
| GC0000172A (en) | 2006-03-29 |
| US20030022850A1 (en) | 2003-01-30 |
| JP2002513579A (ja) | 2002-05-14 |
| NO20005586L (no) | 2001-01-03 |
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