HUP0100489A2 - Új piperidin-4-szulfonamid-vegyületek, eljárás előállításukra és ezeket tartalmazó gyógyászati készítmények - Google Patents
Új piperidin-4-szulfonamid-vegyületek, eljárás előállításukra és ezeket tartalmazó gyógyászati készítményekInfo
- Publication number
- HUP0100489A2 HUP0100489A2 HU0100489A HUP0100489A HUP0100489A2 HU P0100489 A2 HUP0100489 A2 HU P0100489A2 HU 0100489 A HU0100489 A HU 0100489A HU P0100489 A HUP0100489 A HU P0100489A HU P0100489 A2 HUP0100489 A2 HU P0100489A2
- Authority
- HU
- Hungary
- Prior art keywords
- group
- hydrogen atom
- optionally
- vascular
- prevention
- Prior art date
Links
- SMXMELMJCICPJG-UHFFFAOYSA-N piperidine-4-sulfonamide Chemical class NS(=O)(=O)C1CCNCC1 SMXMELMJCICPJG-UHFFFAOYSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 230000002792 vascular Effects 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 206010048554 Endothelial dysfunction Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 206010034576 Peripheral ischaemia Diseases 0.000 abstract 1
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000003143 atherosclerotic effect Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000008694 endothelial dysfunction Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 230000002107 myocardial effect Effects 0.000 abstract 1
- 208000031225 myocardial ischemia Diseases 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
- 125000004385 trihaloalkyl group Chemical group 0.000 abstract 1
- 230000024883 vasodilation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
A találmány tárgyát az új (I) általános képletű piperidin-4-szulfonamid-vegyületek, izomerjeik, hidrátjaik, szolvátjaik ésgyógyászati szempontból elfogadható savval vagy bázissal alkotottaddíciós sóik, ezek előállítása és ezeket tartalmazó gyógyászatikészítmények képezik. Az (I) általános képletben R1 jelentésehidrogénatom vagy alkilcsoport, R2a és R2b azonos vagy különböző,jelentésük hidrogénatom, halogénatom, alkilcsoport, hidroxilcsoport,alkoxicsoport, trihalogénalkil-csoport, cianocsoport, nitrocsoport,aminocsoport, alkilaminocsoport és dialkilaminocsoport, R3 jelentésehidrogénatom vagy hidroxilcsoport, X jelentése oxigénatom vagymetiléncsoport, V jelentése alkiléncsoport, amely adott esetben egyvagy több telítetlenséggel bír, és adott esetben helyettesített lehet,U jelentése vegyértékkötés, vagy alkiléncsoport, W jelentése aril-vagy heteroarilcsoport, amelyek mindegyike adott esetbenhelyettesített tehet. A találmány tárgyát képezik még a fentigyógyászati készítmények endoteliális diszfunkcióval kapcsolatosmegbetegedések vagy patológiás állapotok kezelésére szolgálógyógyszerként való alkalmazásra, különösen ateroszklerotikuskárosodások kifejlődésének, kiterjedésének és ezzel kapcsolatoskomplikációknak a megelőzésére, ér-bypasst, értágítást, ér-repermeabilizálást és szívátültetést követő ér-komplikációkmegelőzésére vagy miokardiális vagy perifériás isémia,szívelégtelenség és tüdő artériás hipertenzió kezelésére szolgálógyógyszerként való alkalmazásra. Ó
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0001171A FR2804429B1 (fr) | 2000-01-31 | 2000-01-31 | Nouveaux derives de 4-sulfonamides piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU0100489D0 HU0100489D0 (en) | 2001-04-28 |
| HUP0100489A2 true HUP0100489A2 (hu) | 2002-05-29 |
| HUP0100489A3 HUP0100489A3 (en) | 2002-10-28 |
Family
ID=8846469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0100489A HUP0100489A3 (en) | 2000-01-31 | 2001-01-30 | New piperidine-4-sulphonamide compounds, process for their preparation and pharmaceutical compositions containing them |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6323217B2 (hu) |
| EP (1) | EP1122254B1 (hu) |
| JP (1) | JP3513493B2 (hu) |
| KR (1) | KR100463369B1 (hu) |
| CN (1) | CN1298705C (hu) |
| AR (1) | AR027335A1 (hu) |
| AT (1) | ATE294175T1 (hu) |
| AU (1) | AU774808B2 (hu) |
| BR (1) | BR0100234A (hu) |
| CA (1) | CA2332513C (hu) |
| DE (1) | DE60110278T2 (hu) |
| DK (1) | DK1122254T3 (hu) |
| EA (1) | EA003096B1 (hu) |
| ES (1) | ES2241757T3 (hu) |
| FR (1) | FR2804429B1 (hu) |
| HK (1) | HK1039117B (hu) |
| HU (1) | HUP0100489A3 (hu) |
| MX (1) | MXPA01000945A (hu) |
| NO (1) | NO320387B1 (hu) |
| NZ (1) | NZ509636A (hu) |
| PL (1) | PL345528A1 (hu) |
| PT (1) | PT1122254E (hu) |
| SI (1) | SI1122254T1 (hu) |
| ZA (1) | ZA200100864B (hu) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60109148T2 (de) * | 2000-04-28 | 2006-01-05 | Acadia Pharmaceuticals Inc., San Diego | Muscarinrezeptoren |
| EP1535912A1 (en) * | 2000-04-28 | 2005-06-01 | Arcadia Pharmaceuticals Inc. | Muscarinic agonists |
| AR040336A1 (es) * | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto |
| WO2004046110A1 (ja) * | 2002-11-15 | 2004-06-03 | Yamanouchi Pharmaceutical Co., Ltd. | メラニン凝集ホルモン受容体拮抗剤 |
| JP2008507492A (ja) * | 2004-07-23 | 2008-03-13 | バイエル・クロツプサイエンス・エス・アー | 殺菌剤としてのｎ−［２−（４−ピリジニル）エチル］ベンズアミド誘導体 |
| JP4977465B2 (ja) * | 2004-07-28 | 2012-07-18 | 武田薬品工業株式会社 | ピロロ［２，３−ｃ］ピリジン化合物、その製造方法および用途 |
| TW200630337A (en) * | 2004-10-14 | 2006-09-01 | Euro Celtique Sa | Piperidinyl compounds and the use thereof |
| EP1852421B1 (en) * | 2005-02-25 | 2011-05-04 | Kowa Company, Ltd. | Process for production of 4-fluoroisoquinoline-5-sulfonyl halide or salt thereof |
| WO2007110449A1 (en) | 2006-03-29 | 2007-10-04 | Euro-Celtique S.A. | Benzenesulfonamide compounds and their use |
| WO2007118854A1 (en) | 2006-04-13 | 2007-10-25 | Euro-Celtique S.A. | Benzenesulfonamide compounds and the use thereof |
| WO2007118853A1 (en) | 2006-04-13 | 2007-10-25 | Euro-Celtique S.A. | Benzenesulfonamide compounds and their use as blockers of calcium channels |
| CL2007003223A1 (es) * | 2006-11-10 | 2008-01-11 | Wyeth Corp | Compuestos derivados de piperidinil 4-arilsulfonamidas n-sustituidas, que actuan como moduladores de la proteina sfrp-1; proceso para preparar los compuestos; co mposicion farmaceutica que comprende a dichos copmpuestos y uso de los compuestos para preparar medicamentos para el tratamiento de enfermedades. |
| US8399486B2 (en) * | 2007-04-09 | 2013-03-19 | Purdue Pharma L.P. | Benzenesulfonyl compounds and the use thereof |
| US8765736B2 (en) | 2007-09-28 | 2014-07-01 | Purdue Pharma L.P. | Benzenesulfonamide compounds and the use thereof |
| AR080375A1 (es) | 2010-03-05 | 2012-04-04 | Sanofi Aventis | Procedimiento para la preparacion de 2-(cicloheximetil)-n-{2-[(2s)-1-metilpirrolidin-2-il] etil}-1,2,3,4-tetrahidroisoquinolina- 7-sulfonamida |
| PL395470A1 (pl) | 2011-06-29 | 2013-01-07 | Adamed Spólka Z Ograniczona Odpowiedzialnoscia | Sulfonamidowe pochodne amin alicyklicznych do leczenia chorób osrodkowego ukladu nerwowego |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4956382A (en) * | 1987-02-07 | 1990-09-11 | Pfizer Inc. | Sulfonamide anti-arrhythmic agents |
| US4857301A (en) * | 1987-09-25 | 1989-08-15 | Schering Corporation | Sulfonamide compounds, compositions and method of use |
| FR2679906B1 (fr) * | 1991-07-31 | 1995-01-20 | Adir | Nouvelles (isoquinolein-5 yl) sulfonamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| DK148392D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Heterocykliske forbindelser |
| AU6971794A (en) * | 1993-05-26 | 1994-12-20 | Smithkline Beecham Laboratoires Pharmaceutiques | Novel compounds |
| FR2716679B1 (fr) * | 1994-02-25 | 1996-04-05 | Adir | Nouvelles sulfonamides substituées, leur procédé de préparation et les compositions pharmaceutiques les renfermant. |
| HN1997000027A (es) * | 1996-12-06 | 1997-06-05 | Pfizer Prod Inc | Derivados de 6-fenil piridil - 2 amina |
-
2000
- 2000-01-31 FR FR0001171A patent/FR2804429B1/fr not_active Expired - Fee Related
-
2001
- 2001-01-23 CN CNB011123346A patent/CN1298705C/zh not_active Expired - Fee Related
- 2001-01-26 MX MXPA01000945A patent/MXPA01000945A/es unknown
- 2001-01-30 DE DE60110278T patent/DE60110278T2/de not_active Expired - Fee Related
- 2001-01-30 EP EP01400225A patent/EP1122254B1/fr not_active Expired - Lifetime
- 2001-01-30 SI SI200130342T patent/SI1122254T1/xx unknown
- 2001-01-30 HU HU0100489A patent/HUP0100489A3/hu unknown
- 2001-01-30 US US09/772,569 patent/US6323217B2/en not_active Expired - Fee Related
- 2001-01-30 NZ NZ509636A patent/NZ509636A/en unknown
- 2001-01-30 AT AT01400225T patent/ATE294175T1/de not_active IP Right Cessation
- 2001-01-30 CA CA002332513A patent/CA2332513C/fr not_active Expired - Fee Related
- 2001-01-30 NO NO20010522A patent/NO320387B1/no unknown
- 2001-01-30 DK DK01400225T patent/DK1122254T3/da active
- 2001-01-30 EA EA200100090A patent/EA003096B1/ru unknown
- 2001-01-30 PT PT01400225T patent/PT1122254E/pt unknown
- 2001-01-30 ES ES01400225T patent/ES2241757T3/es not_active Expired - Lifetime
- 2001-01-31 ZA ZA200100864A patent/ZA200100864B/xx unknown
- 2001-01-31 AR ARP010100429A patent/AR027335A1/es not_active Application Discontinuation
- 2001-01-31 PL PL01345528A patent/PL345528A1/xx unknown
- 2001-01-31 BR BR0100234-1A patent/BR0100234A/pt not_active IP Right Cessation
- 2001-01-31 JP JP2001022954A patent/JP3513493B2/ja not_active Expired - Fee Related
- 2001-01-31 AU AU16747/01A patent/AU774808B2/en not_active Ceased
- 2001-01-31 KR KR10-2001-0004591A patent/KR100463369B1/ko not_active IP Right Cessation
-
2002
- 2002-01-16 HK HK02100331.6A patent/HK1039117B/zh not_active IP Right Cessation
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