HUP0100270A3 - Peptids for inhibiting betha-amyloid peptide release and/or its synthesis, pharmaceutical compositions comprising thereof and their use - Google Patents
Peptids for inhibiting betha-amyloid peptide release and/or its synthesis, pharmaceutical compositions comprising thereof and their useInfo
- Publication number
- HUP0100270A3 HUP0100270A3 HU0100270A HUP0100270A HUP0100270A3 HU P0100270 A3 HUP0100270 A3 HU P0100270A3 HU 0100270 A HU0100270 A HU 0100270A HU P0100270 A HUP0100270 A HU P0100270A HU P0100270 A3 HUP0100270 A3 HU P0100270A3
- Authority
- HU
- Hungary
- Prior art keywords
- betha
- peptids
- inhibiting
- synthesis
- pharmaceutical compositions
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75544296A | 1996-11-22 | 1996-11-22 | |
| US80742797A | 1997-02-28 | 1997-02-28 | |
| US80852897A | 1997-02-28 | 1997-02-28 | |
| US80752897A | 1997-02-28 | 1997-02-28 | |
| PCT/US1997/020804 WO1998022494A2 (en) | 1996-11-22 | 1997-11-21 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0100270A2 HUP0100270A2 (hu) | 2001-08-28 |
| HUP0100270A3 true HUP0100270A3 (en) | 2001-09-28 |
Family
ID=27505670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0100270A HUP0100270A3 (en) | 1996-11-22 | 1997-11-21 | Peptids for inhibiting betha-amyloid peptide release and/or its synthesis, pharmaceutical compositions comprising thereof and their use |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0942924A2 (sh) |
| JP (1) | JP2001503782A (sh) |
| KR (1) | KR20000069064A (sh) |
| CN (1) | CN1238779A (sh) |
| AR (1) | AR016751A1 (sh) |
| AU (1) | AU5356198A (sh) |
| BR (1) | BR9713400A (sh) |
| CA (1) | CA2267634A1 (sh) |
| CO (1) | CO4910156A1 (sh) |
| CZ (1) | CZ122899A3 (sh) |
| EA (1) | EA199900490A1 (sh) |
| HR (1) | HRP970627A2 (sh) |
| HU (1) | HUP0100270A3 (sh) |
| ID (1) | ID22044A (sh) |
| IL (1) | IL129083A0 (sh) |
| NO (1) | NO992368L (sh) |
| NZ (1) | NZ334690A (sh) |
| PE (1) | PE16999A1 (sh) |
| TR (3) | TR199901133T2 (sh) |
| WO (1) | WO1998022494A2 (sh) |
| YU (1) | YU46097A (sh) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19616486C5 (de) | 1996-04-25 | 2016-06-30 | Royalty Pharma Collection Trust | Verfahren zur Senkung des Blutglukosespiegels in Säugern |
| US6191166B1 (en) * | 1997-11-21 | 2001-02-20 | Elan Pharmaceuticals, Inc. | Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis |
| US6635632B1 (en) | 1996-12-23 | 2003-10-21 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| DE19823831A1 (de) | 1998-05-28 | 1999-12-02 | Probiodrug Ges Fuer Arzneim | Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen |
| AU4707999A (en) * | 1998-06-22 | 2000-01-10 | Elan Pharmaceuticals, Inc. | Compounds for inhibiting beta-amyloid peptide release and/or its synthesis |
| AU4710499A (en) * | 1998-06-22 | 2000-01-10 | Elan Pharmaceuticals, Inc. | Cyclic amino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use ofsuch compounds |
| US6958330B1 (en) | 1998-06-22 | 2005-10-25 | Elan Pharmaceuticals, Inc. | Polycyclic α-amino-ε-caprolactams and related compounds |
| AU4710199A (en) * | 1998-06-22 | 2000-01-10 | Elan Pharmaceuticals, Inc. | Compounds for inhibiting beta-amyloid peptide release and/or its synthesis |
| US6552013B1 (en) | 1998-06-22 | 2003-04-22 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| DE19828114A1 (de) | 1998-06-24 | 2000-01-27 | Probiodrug Ges Fuer Arzneim | Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV |
| DE19828113A1 (de) * | 1998-06-24 | 2000-01-05 | Probiodrug Ges Fuer Arzneim | Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV |
| DE19834591A1 (de) | 1998-07-31 | 2000-02-03 | Probiodrug Ges Fuer Arzneim | Verfahren zur Steigerung des Blutglukosespiegels in Säugern |
| US6486350B1 (en) | 1998-09-30 | 2002-11-26 | Elan Pharmaceuticals Inc. | Biological reagents and methods for determining the mechanism in the generation of β-amyloid peptide |
| US6737038B1 (en) | 1998-11-12 | 2004-05-18 | Bristol-Myers Squibb Company | Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging |
| AU772575B2 (en) | 1998-12-10 | 2004-04-29 | F. Hoffmann-La Roche Ag | Procollagen C-proteinase inhibitors |
| US6723711B2 (en) | 1999-05-07 | 2004-04-20 | Texas Biotechnology Corporation | Propanoic acid derivatives that inhibit the binding of integrins to their receptors |
| TR200103427T2 (tr) * | 1999-05-07 | 2002-10-21 | Texas Biotechnology Corporation | Integrinlerin reseptörlerine bağlanmasını engelleyen propanoik asit türevleri. |
| US6972296B2 (en) | 1999-05-07 | 2005-12-06 | Encysive Pharmaceuticals Inc. | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors |
| DE19926233C1 (de) | 1999-06-10 | 2000-10-19 | Probiodrug Ges Fuer Arzneim | Verfahren zur Herstellung von Thiazolidin |
| DE19940130A1 (de) | 1999-08-24 | 2001-03-01 | Probiodrug Ges Fuer Arzneim | Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung |
| CA2388750A1 (en) * | 1999-11-09 | 2001-05-17 | James Edmund Audia | .beta.-aminoacid compounds useful for inhibiting .beta.-amyloid peptide release and/or its synthesis |
| DE60137216D1 (de) | 2000-03-31 | 2009-02-12 | Prosidion Ltd | Verbesserung der aktivität der inselzellen bei diabetes mellitus und dessen prävention |
| WO2001087354A2 (en) | 2000-05-17 | 2001-11-22 | Bristol-Myers Squibb Pharma Company | Use of small molecule radioligands for diagnostic imaging |
| BR0106717A (pt) | 2000-06-01 | 2002-04-16 | Bristol Myers Squibb Pharma Co | Compostos, composição farmacêutica e usos dos compostos de lactama inovadora |
| FR2832152A1 (fr) * | 2001-11-09 | 2003-05-16 | Aventis Pharma Sa | Utilisation de derives de 2-amino-thiazoline comme inhibiteurs de no-synthase inductible |
| GB0016681D0 (en) | 2000-07-06 | 2000-08-23 | Merck Sharp & Dohme | Therapeutic compounds |
| US6432944B1 (en) | 2000-07-06 | 2002-08-13 | Bristol-Myers Squibb Company | Benzodiazepinone β-amyloid inhibitors: arylacetamidoalanyl derivatives |
| US7132104B1 (en) | 2000-10-27 | 2006-11-07 | Probiodrug Ag | Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders |
| US6890905B2 (en) | 2001-04-02 | 2005-05-10 | Prosidion Limited | Methods for improving islet signaling in diabetes mellitus and for its prevention |
| DE10150203A1 (de) | 2001-10-12 | 2003-04-17 | Probiodrug Ag | Peptidylketone als Inhibitoren der DPIV |
| US20030130199A1 (en) | 2001-06-27 | 2003-07-10 | Von Hoersten Stephan | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents |
| US7368421B2 (en) | 2001-06-27 | 2008-05-06 | Probiodrug Ag | Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis |
| AR039059A1 (es) | 2001-08-06 | 2005-02-09 | Sanofi Aventis | Compuesto derivado de acilaminotiazol, su utilizacion, procedimientos para prepararlo, composicion farmaceutica que lo comprende, y compuestos intermediarios |
| FR2840899B1 (fr) * | 2002-06-12 | 2005-02-25 | Sanofi Synthelabo | Derives d'acylaminothiazole, leur preparation et leur utilisation en therapeutique |
| US6844316B2 (en) | 2001-09-06 | 2005-01-18 | Probiodrug Ag | Inhibitors of dipeptidyl peptidase I |
| DE10143840A1 (de) * | 2001-09-06 | 2003-03-27 | Probiodrug Ag | Neue Inhibitoren der Dipeptidylpeptidase I |
| ES2256583T3 (es) | 2001-11-09 | 2006-07-16 | Aventis Pharma S.A. | Derivados de 2-amino-tiazolina y su uso como inhibidores de la no-sintasa inducible. |
| DE20220238U1 (de) | 2002-02-28 | 2003-05-08 | Probiodrug AG, 06120 Halle | Glutaminyl basierte DPIV Inhibitoren |
| KR101145252B1 (ko) * | 2003-01-08 | 2012-05-24 | 유니버시티 오브 워싱톤 | 항균제 |
| KR20100106630A (ko) | 2003-05-05 | 2010-10-01 | 프로비오드룩 아게 | 글루타미닐 및 글루타메이트 사이클라제의 이펙터의 용도 |
| JP4806628B2 (ja) | 2003-05-05 | 2011-11-02 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤 |
| EP1666068A4 (en) * | 2003-09-24 | 2010-08-04 | Santen Pharmaceutical Co Ltd | REMEDY FOR EYE DISEASES ACCOMPANIED BY OPTICAL NERVE INJURIES |
| BRPI0415409A (pt) | 2003-10-15 | 2006-12-05 | Probiodrug Ag | uso de efetuadores de ciclases de glutaminila e glutamato |
| EP2662353A3 (en) | 2007-06-12 | 2014-04-02 | Achaogen, Inc. | Antibacterial agents |
| EP2062909A1 (en) * | 2007-11-21 | 2009-05-27 | SOLVAY (Société Anonyme) | Peptide production and purification process |
| BG110141A (en) | 2008-05-23 | 2009-12-31 | "Софарма" Ад | GALANTAMINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND USE |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| WO2017004560A1 (en) * | 2015-07-02 | 2017-01-05 | The Regents Of The University Of California | Methods and compositions for amyloid aggregates |
| WO2022150314A1 (en) * | 2021-01-05 | 2022-07-14 | Southern Research Institute | Modulators of programmed death-ligand-1 |
| WO2024076635A2 (en) * | 2022-10-05 | 2024-04-11 | Buck Institute For Research On Aging | Suppressors of site iq electron leak and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL97428A0 (en) * | 1990-03-05 | 1992-06-21 | Cephalon Inc | Chymotrypsin-like proteases and their inhibitors |
| WO1995013084A1 (en) * | 1992-05-11 | 1995-05-18 | Miles Inc. | Cathepsin d is an amyloidogenic protease in alzheimer's disease |
| CZ184194A3 (en) * | 1993-08-09 | 1995-03-15 | Lilly Co Eli | Aspartylprotease inhibitor and method of identifying thereof |
| PT721449E (pt) * | 1993-10-01 | 2002-06-28 | Merrell Pharma Inc | Inibidores da producao da proteina beta-amiloide |
| US5804560A (en) * | 1995-01-06 | 1998-09-08 | Sibia Neurosciences, Inc. | Peptide and peptide analog protease inhibitors |
| US6017887A (en) * | 1995-01-06 | 2000-01-25 | Sibia Neurosciences, Inc. | Peptide, peptide analog and amino acid analog protease inhibitors |
| JPH11506923A (ja) * | 1995-06-06 | 1999-06-22 | アセナ ニューロサイエンシーズ，インコーポレイテッド | 新しいカテプシンならびにその阻害のための方法および組成物 |
-
1997
- 1997-11-18 AR ARP970105393A patent/AR016751A1/es not_active Application Discontinuation
- 1997-11-19 HR HR08/808,528A patent/HRP970627A2/hr not_active Application Discontinuation
- 1997-11-20 PE PE1997001056A patent/PE16999A1/es not_active Application Discontinuation
- 1997-11-21 CN CN97199803A patent/CN1238779A/zh active Pending
- 1997-11-21 HU HU0100270A patent/HUP0100270A3/hu unknown
- 1997-11-21 TR TR1999/01133T patent/TR199901133T2/xx unknown
- 1997-11-21 EA EA199900490A patent/EA199900490A1/ru unknown
- 1997-11-21 EP EP97950601A patent/EP0942924A2/en not_active Withdrawn
- 1997-11-21 CO CO97068215A patent/CO4910156A1/es unknown
- 1997-11-21 YU YU46097A patent/YU46097A/sh unknown
- 1997-11-21 WO PCT/US1997/020804 patent/WO1998022494A2/en not_active Application Discontinuation
- 1997-11-21 CA CA002267634A patent/CA2267634A1/en not_active Abandoned
- 1997-11-21 AU AU53561/98A patent/AU5356198A/en not_active Abandoned
- 1997-11-21 NZ NZ334690A patent/NZ334690A/en unknown
- 1997-11-21 KR KR1019997004486A patent/KR20000069064A/ko not_active Application Discontinuation
- 1997-11-21 BR BR9713400-7A patent/BR9713400A/pt not_active IP Right Cessation
- 1997-11-21 TR TR1999/02937T patent/TR199902937T2/xx unknown
- 1997-11-21 JP JP52375698A patent/JP2001503782A/ja active Pending
- 1997-11-21 ID IDW990394A patent/ID22044A/id unknown
- 1997-11-21 CZ CZ991228A patent/CZ122899A3/cs unknown
- 1997-11-21 IL IL12908397A patent/IL129083A0/xx unknown
- 1997-11-21 TR TR1999/02938T patent/TR199902938T2/xx unknown
-
1999
- 1999-05-14 NO NO992368A patent/NO992368L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0100270A2 (hu) | 2001-08-28 |
| CN1238779A (zh) | 1999-12-15 |
| JP2001503782A (ja) | 2001-03-21 |
| CZ122899A3 (cs) | 1999-10-13 |
| WO1998022494A3 (en) | 1998-11-26 |
| TR199902938T2 (xx) | 2002-06-21 |
| TR199902937T2 (xx) | 2001-01-22 |
| AU5356198A (en) | 1998-06-10 |
| EP0942924A2 (en) | 1999-09-22 |
| NO992368L (no) | 1999-06-21 |
| IL129083A0 (en) | 2000-02-17 |
| PE16999A1 (es) | 1999-02-19 |
| CA2267634A1 (en) | 1998-05-28 |
| YU46097A (sh) | 2000-10-30 |
| NO992368D0 (no) | 1999-05-14 |
| ID22044A (id) | 1999-08-26 |
| NZ334690A (en) | 2001-09-28 |
| EA199900490A1 (ru) | 2000-02-28 |
| AR016751A1 (es) | 2001-08-01 |
| TR199901133T2 (xx) | 1999-07-21 |
| WO1998022494A2 (en) | 1998-05-28 |
| HRP970627A2 (en) | 1998-08-31 |
| KR20000069064A (ko) | 2000-11-25 |
| BR9713400A (pt) | 2000-01-25 |
| CO4910156A1 (es) | 2000-04-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0100270A3 (en) | Peptids for inhibiting betha-amyloid peptide release and/or its synthesis, pharmaceutical compositions comprising thereof and their use | |
| ZA981627B (en) | Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting ß-amyloid peptide release and/or its synthesis by use of such compounds. | |
| HUP0400887A3 (en) | Glycopeptide derivatives and pharmaceutical compositions containing the same | |
| HU0500549D0 (en) | Azolo-pyridimidines, pharmaceutical compositions containing the same and use thereof | |
| HUP0101130A3 (en) | Aminoindan derivatives and pharmaceutical compositions comprising them | |
| HUP9901199A3 (en) | Tropane-derivatives, inhibiting neurotransmitter re-uptake, their preparation, pharmaceutical compositions containing them and use of the compounds | |
| HUP0001107A3 (en) | Monocyclic l-nucleosides, analogs and pharmaceutical compositions thereof | |
| HUP0100100A3 (en) | Hepatitis c inhibitor peptide analogues, pharmaceutical compositions comprising thereof and their use | |
| HUP0100149A3 (en) | Antipicornaviral peptide derivatives pharmaceutical compositions comprising thereof and their use | |
| IL138533A0 (en) | Pharmaceutical compositions for prolonged peptide release and preparation method | |
| HUP0000733A3 (en) | Aminoguanidines and alkoxyguanidines as and pharmaceutical compositions containing them | |
| HUP0103265A3 (en) | Cyclic prosaposin-derived peptides, pharmaceutical compositions comprising thereof and their use | |
| AU4133701A (en) | Methods and compositions for peptide synthesis | |
| HUP0102579A3 (en) | Peptide antiangiogenic drugs, pharmaceutical compositions comprising thereof and their use | |
| HUP0103884A3 (en) | Arylsulfonanilide urea-derivatives, pharmaceutical compositions containing them and their use | |
| HUP0003592A3 (en) | Lh-rh peptide analogues, their use and pharmaceutical compositions containing them | |
| HUP0102255A3 (en) | Vla-4 inhibitor omepupa-v, pharmaceutical compositions comprising thereof and their use | |
| HUP9904694A3 (en) | Spiropyrrolidine derivatives, their use and pharmaceutical compositions containing them | |
| AU5204799A (en) | Compounds for inhibiting beta-amyloid peptide release and/or its synthesis | |
| HUP0100082A3 (en) | Thrombin inhibitor, peptide derivatives, pharmaceutical compositions comprising thereof and their use | |
| EG24463A (en) | Modified release pharmaceutical composition | |
| HUP0000460A3 (en) | Imidazopyridazines and pharmaceutical compositions thereof | |
| HUP0101733A3 (en) | Pharmaceutical compositions containing sulfonyl-dipeptides and their use | |
| IL125908A0 (en) | Peptides and pharmaceutical compositions comprising same | |
| IL125262A0 (en) | Synthetic peptides and pharmaceutical compositions comprising them |