HUP0004580A2 - Kapacitív affinitási szenzor - Google Patents

Kapacitív affinitási szenzor

Info

Publication number
HUP0004580A2
HUP0004580A2 HU0004580A HUP0004580A HUP0004580A2 HU P0004580 A2 HUP0004580 A2 HU P0004580A2 HU 0004580 A HU0004580 A HU 0004580A HU P0004580 A HUP0004580 A HU P0004580A HU P0004580 A2 HUP0004580 A2 HU P0004580A2
Authority
HU
Hungary
Prior art keywords
affinity sensor
subject
compounds
monolayer
detected
Prior art date
Application number
HU0004580A
Other languages
English (en)
Inventor
Christine Berggren
Gillis Johansson
Original Assignee
Ab Sangtec Medical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab Sangtec Medical filed Critical Ab Sangtec Medical
Publication of HUP0004580A2 publication Critical patent/HUP0004580A2/hu
Publication of HUP0004580A3 publication Critical patent/HUP0004580A3/hu

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2610/00—Assays involving self-assembled monolayers [SAMs]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

A találmány tárgya eljárás kapacitív ellenállás mérése alapjánkimutatni kívánt vegyületek jelenlétének kimutatására alkalmasaffinitási szenzor előállítására. A találmány szerinti eljárás során adetektort úgy alakítják ki, hogy nemesfémfelszínen kapcsolócsoportottartalmazó, SAM-létrehozó molekulákból önszerveződő monoréteget hoznaklétre, és a kialakított monotréteghez a kimutatni kívánt molekulátspecifikusan kötni képes ligandumot kapcsolnak, majd a monorétegetismételten SAM-létrehozó molekulákkal érintkeztetik. A találmánytárgyát képezi a találmány szerinti eljárással előállított kapacitívaffinitási szenzor is. A találmány tárgyát képezi továbbá egy eljáráskimutatni kívánt vegyületek kimutatására, a találmány szerintiaffinitási szenzor alkalmazásával. A találmány szerinti megoldásalkalmas kiválasztott vegyületek gyors, hatékony és specifikuskimutatására. Ó
HU0004580A 1997-09-15 1998-09-02 Capacity affinity sensor HUP0004580A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9703314A SE9703314D0 (sv) 1997-09-15 1997-09-15 Capacity affinity sensor
PCT/SE1998/001562 WO1999014596A1 (en) 1997-09-15 1998-09-02 Capacity affinity sensor

Publications (2)

Publication Number Publication Date
HUP0004580A2 true HUP0004580A2 (hu) 2001-04-28
HUP0004580A3 HUP0004580A3 (en) 2003-05-28

Family

ID=20408243

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004580A HUP0004580A3 (en) 1997-09-15 1998-09-02 Capacity affinity sensor

Country Status (12)

Country Link
US (1) US6436699B1 (hu)
EP (1) EP1018010A1 (hu)
JP (1) JP2001516881A (hu)
AU (1) AU742122B2 (hu)
CA (1) CA2303461A1 (hu)
HU (1) HUP0004580A3 (hu)
NO (1) NO20001326D0 (hu)
NZ (1) NZ502798A (hu)
PL (1) PL339263A1 (hu)
SE (1) SE9703314D0 (hu)
WO (1) WO1999014596A1 (hu)
ZA (1) ZA988077B (hu)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824473A (en) 1993-12-10 1998-10-20 California Institute Of Technology Nucleic acid mediated electron transfer
US6071699A (en) 1996-06-07 2000-06-06 California Institute Of Technology Nucleic acid mediated electron transfer
US7045285B1 (en) 1996-11-05 2006-05-16 Clinical Micro Sensors, Inc. Electronic transfer moieties attached to peptide nucleic acids
US6096273A (en) 1996-11-05 2000-08-01 Clinical Micro Sensors Electrodes linked via conductive oligomers to nucleic acids
US6686150B1 (en) 1998-01-27 2004-02-03 Clinical Micro Sensors, Inc. Amplification of nucleic acids with electronic detection
EP1055004A2 (de) * 1998-02-20 2000-11-29 Wolfbeis, Otto Samuel Vorrichtung zur detektion von oligo- und/oder polynukleotid-hybridisierungen
US6290839B1 (en) 1998-06-23 2001-09-18 Clinical Micro Sensors, Inc. Systems for electrophoretic transport and detection of analytes
US6761816B1 (en) 1998-06-23 2004-07-13 Clinical Micro Systems, Inc. Printed circuit boards with monolayers and capture ligands
US6740518B1 (en) 1998-09-17 2004-05-25 Clinical Micro Sensors, Inc. Signal detection techniques for the detection of analytes
AU1241000A (en) * 1998-10-27 2000-05-15 Clinical Micro Sensors, Inc. Detection of target analytes using particles and electrodes
US6942771B1 (en) 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
EP1218541B1 (en) 1999-07-26 2008-12-10 Clinical Micro Sensors, Inc. Sequence determination of nucleic acids using electronic detection
DE10048997A1 (de) * 2000-09-27 2002-04-11 Santron Ag Vorrichtung zum Nachweis geladener Makromoleküle
AU2002241803A1 (en) * 2000-10-20 2002-06-18 The Board Of Trustees Of The Leland Stanford Junior University Transient electrical signal based methods and devices for characterizing molecular interaction and/or motion in a sample
US6821529B2 (en) 2001-09-05 2004-11-23 Deanna Jean Nelson Oligo(ethylene glycoll)-terminated 1,2-dithiolanes and their conjugates useful for preparing self-assembled monolayers
US6756354B2 (en) * 2001-09-05 2004-06-29 Deanna Jean Nelson Therapeutic compositions containing oligo (ethylene glycol)-terminated 1,2-dithiolanes and their conjugates
WO2003093406A2 (en) * 2002-05-01 2003-11-13 Massachusetts Institute Of Technology Microfermentors for rapid screening and analysis of biochemical processes
US20060199260A1 (en) * 2002-05-01 2006-09-07 Zhiyu Zhang Microbioreactor for continuous cell culture
US6893966B2 (en) * 2002-11-27 2005-05-17 International Business Machines Corporation Method of patterning the surface of an article using positive microcontact printing
US7138121B2 (en) 2003-01-23 2006-11-21 Spangler Brenda D Biosensors utilizing dendrimer-immobilized ligands and there use thereof
AT413214B (de) * 2003-01-24 2005-12-15 Sy Lab Vgmbh Messanordnung und verfahren zur detektion einer dna-sequenz
US7015011B2 (en) * 2003-04-18 2006-03-21 Electronic Biosciences, Llc Circuit and method to non-invasively detect the electrical potential of a cell or neuron
KR100547015B1 (ko) * 2003-05-23 2006-01-26 주식회사 올메디쿠스 일정한 크기 이상의 분석물질을 정량 분석하기 위한바이오센서 및 그 제조방법
US7682833B2 (en) * 2003-09-10 2010-03-23 Abbott Point Of Care Inc. Immunoassay device with improved sample closure
US7723099B2 (en) * 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
JP2007526452A (ja) * 2003-11-20 2007-09-13 バイオワーン・エルエルシー 生物学的物質を検出する方法及び装置
US20080176341A1 (en) * 2004-08-19 2008-07-24 Reverse Protemics Research Institute Co., Ltd. Method for Suppressing Intermolecular Nonspecific Interaction and for Intensifying Intermolecular Specific Interaction on Metal Surface
JP4742339B2 (ja) * 2005-06-14 2011-08-10 独立行政法人産業技術総合研究所 シアル酸含有３糖化合物、それを用いるサーズウイルスまたはサーズスパイク蛋白質の検出
JP4742340B2 (ja) * 2005-06-14 2011-08-10 独立行政法人産業技術総合研究所 硫酸基含有糖化合物、それを用いるサーズウイルスまたはインフルエンザウイルスの検出
US20090259217A1 (en) * 2008-04-09 2009-10-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems associated with delivery of one or more agents to an individual
US20100204936A1 (en) * 2009-02-11 2010-08-12 Midorion Ab Probing Electrode/Solution Interfaces
WO2011075663A1 (en) * 2009-12-18 2011-06-23 Abbott Point Of Care Inc. Integrated hinged cartridge housings for sample analysis
WO2012060758A1 (en) * 2010-11-01 2012-05-10 Capsenze A method of measuring a capacitance and a use
JP5202761B2 (ja) * 2011-06-10 2013-06-05 パナソニック株式会社 抗体を自己組織化膜上に固定する方法
CN105190310B (zh) 2013-03-11 2018-04-10 托莱多大学 用于体内原位和/或实时靶定分析物的生物感应器装置及其制造与使用方法
WO2014159615A2 (en) 2013-03-14 2014-10-02 Abbott Point Of Care Inc Thermal control system for controlling the temperature of a fluid
EP3080294B1 (en) 2013-12-12 2018-06-13 Altratech Limited A capacitive sensor and method of use
CN105980558B (zh) 2013-12-12 2021-08-24 阿尔查技术有限公司 样品制备方法和设备
US9702847B2 (en) * 2014-12-30 2017-07-11 Avails Medical, Inc. Systems and methods for detecting a substance in bodily fluid
US11459601B2 (en) 2017-09-20 2022-10-04 Altratech Limited Diagnostic device and system
KR102316080B1 (ko) * 2019-10-25 2021-10-21 가천대학교 산학협력단 혈청내 IgM 류마티즘 인자를 민감하게 검출하기 위한 비표지 전기화학 임피던스 측정 면역센서 및 그 제조방법
KR102352618B1 (ko) * 2019-12-31 2022-01-19 프리시젼바이오 주식회사 정전 용량 센서를 이용한 면역 분석 검사 스트립
KR102349583B1 (ko) * 2020-02-07 2022-01-10 가천대학교 산학협력단 빗살 체인형 전극 형태의 아밀로이드 베타 펩타이드 검출 센서

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822566A (en) * 1985-11-19 1989-04-18 The Johns Hopkins University Optimized capacitive sensor for chemical analysis and measurement
FR2609474B1 (fr) * 1987-01-09 1991-04-26 Poudres & Explosifs Ste Nale Procede de synthese electrochimique d'acides carboxyliques
DE3852036T2 (de) * 1987-07-27 1995-03-09 Commw Scient Ind Res Org Rezeptormembranen.
WO1993008464A1 (en) * 1991-10-21 1993-04-29 Holm Kennedy James W Method and device for biochemical sensing
DE4430023A1 (de) * 1994-08-24 1996-02-29 Boehringer Mannheim Gmbh Elektrochemischer Sensor
SE9403245D0 (sv) * 1994-09-26 1994-09-26 Pharmacia Biosensor Ab Improvements relating to bilayer lipid membranes

Also Published As

Publication number Publication date
US6436699B1 (en) 2002-08-20
ZA988077B (en) 1999-03-04
NO20001326L (no) 2000-03-14
AU9099698A (en) 1999-04-05
NZ502798A (en) 2001-04-27
SE9703314D0 (sv) 1997-09-15
EP1018010A1 (en) 2000-07-12
JP2001516881A (ja) 2001-10-02
AU742122B2 (en) 2001-12-20
PL339263A1 (en) 2000-12-04
CA2303461A1 (en) 1999-03-25
NO20001326D0 (no) 2000-03-14
HUP0004580A3 (en) 2003-05-28
WO1999014596A1 (en) 1999-03-25

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