HUP0001458A2 - Specifikus hasnyálmirigy lipáz inhibitor hatású peptidek, ezeket tartalmazó gyógyszerkészítmények és diagnosztikai reagensek, valamint ezek alkalmazása - Google Patents

Specifikus hasnyálmirigy lipáz inhibitor hatású peptidek, ezeket tartalmazó gyógyszerkészítmények és diagnosztikai reagensek, valamint ezek alkalmazása

Info

Publication number
HUP0001458A2
HUP0001458A2 HU0001458A HUP0001458A HUP0001458A2 HU P0001458 A2 HUP0001458 A2 HU P0001458A2 HU 0001458 A HU0001458 A HU 0001458A HU P0001458 A HUP0001458 A HU P0001458A HU P0001458 A2 HUP0001458 A2 HU P0001458A2
Authority
HU
Hungary
Prior art keywords
diagnostical
reagents
pancreatic lipase
applications
pharmaceutical compositions
Prior art date
Application number
HU0001458A
Other languages
English (en)
Inventor
Catherine Chapus
Original Assignee
Laboratoire Laphal (Laboratoire De Pharmacologie Appliquee)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Laphal (Laboratoire De Pharmacologie Appliquee) filed Critical Laboratoire Laphal (Laboratoire De Pharmacologie Appliquee)
Publication of HUP0001458A2 publication Critical patent/HUP0001458A2/hu
Publication of HUP0001458A3 publication Critical patent/HUP0001458A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A találmány hasnyálmirigy lipáz C-terminális fragmensét tartalmazópeptidre - amely magában foglalja a kolipáz felismerésére szolgálóhelyet - és ilyen peptidet hatóanyagként tartalmazógyógyszerkészítményre és diagnosztikai reagensre vonatkozik. Atalálmány szerinti peptidek alkalmasak a lipidfelesleg jelenlétévelösszefüggő betegségek kezelésére és megelőzésére. Ó
HU0001458A 1997-01-07 1998-01-06 Specific pancreatic lipase inhibitor peptides, pharmaceutical compositions and diagnostical reagents comprising thereof and their applications HUP0001458A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9700071A FR2758143B1 (fr) 1997-01-07 1997-01-07 Inhibiteurs specifiques de la lipase pancreatique et leurs applications
PCT/FR1998/000009 WO1998030588A1 (fr) 1997-01-07 1998-01-06 Inhibiteurs specifiques de la lipase pancreatique et leurs applications

Publications (2)

Publication Number Publication Date
HUP0001458A2 true HUP0001458A2 (hu) 2000-10-28
HUP0001458A3 HUP0001458A3 (en) 2001-04-28

Family

ID=9502405

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001458A HUP0001458A3 (en) 1997-01-07 1998-01-06 Specific pancreatic lipase inhibitor peptides, pharmaceutical compositions and diagnostical reagents comprising thereof and their applications

Country Status (14)

Country Link
US (1) US6432400B1 (hu)
EP (1) EP0970118B1 (hu)
CN (1) CN1248264A (hu)
AT (1) ATE273995T1 (hu)
AU (1) AU727469B2 (hu)
BR (1) BR9806857A (hu)
CA (1) CA2277778C (hu)
CZ (1) CZ294206B6 (hu)
DE (1) DE69825733T2 (hu)
FR (1) FR2758143B1 (hu)
HU (1) HUP0001458A3 (hu)
NZ (1) NZ337087A (hu)
WO (1) WO1998030588A1 (hu)
ZA (1) ZA9894B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000226335A (ja) * 1998-12-04 2000-08-15 Amano Pharmaceut Co Ltd 経口用酵素製剤、酵素含有食材及び酵素製剤の服用方法
US6697668B2 (en) 2001-01-25 2004-02-24 Iomed, Inc. Ocular iontophoretic device and method for using the same
FR2824334B1 (fr) * 2001-05-03 2003-10-10 Coletica Procede pour tester une substance eventuellement active dans le domaine de la lipolyse et son utilisation principalement cosmetique
US20040018197A1 (en) * 2002-04-26 2004-01-29 Promega Corporation Treatment for weight loss
US20040077530A1 (en) * 2002-10-18 2004-04-22 Robert Portman Composition for reducing caloric intake
WO2004090551A2 (en) * 2003-04-08 2004-10-21 Genova, Ltd. Secreted polypeptide species associated with cardiovascular disorders
SE0302253D0 (sv) 2003-08-21 2003-08-21 Forskarpatent I Syd Ab Lipase-colipase inhibitor
GB0920633D0 (en) * 2009-11-25 2010-01-13 Rdbiomed Ltd Inhibition of pancreatic lipase
FR2966734B1 (fr) * 2010-10-29 2014-07-18 Max Rombi Composition comprenant au moins une enzyme proteolytique pour son utilisation pour empecher la synthese des triglycerides
US20130144540A1 (en) * 2011-12-06 2013-06-06 Palo Alto Research Center Incorporated Constrained de novo sequencing of peptides
WO2017079299A1 (en) * 2015-11-03 2017-05-11 Mayo Foundation For Medical Education And Research Using colipase inhibitors to treat pancreatitis
EP4218753A3 (en) 2017-07-12 2023-10-11 Mayo Foundation for Medical Education and Research Compounds for the reducing lipotoxic damage
CN114621336A (zh) * 2020-12-14 2022-06-14 西北农林科技大学 一种酪蛋白源胰脂肪酶抑制肽及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248598A (en) * 1989-05-25 1993-09-28 Ivan E. Modrovich Lipase single reagent system

Also Published As

Publication number Publication date
CZ294206B6 (cs) 2004-10-13
AU727469B2 (en) 2000-12-14
CA2277778A1 (fr) 1998-07-16
EP0970118B1 (fr) 2004-08-18
CA2277778C (fr) 2013-07-02
NZ337087A (en) 2001-01-26
DE69825733T2 (de) 2005-09-01
FR2758143B1 (fr) 1999-02-19
HUP0001458A3 (en) 2001-04-28
ZA9894B (en) 1998-07-08
ATE273995T1 (de) 2004-09-15
BR9806857A (pt) 2000-03-14
EP0970118A1 (fr) 2000-01-12
WO1998030588A1 (fr) 1998-07-16
CZ241499A3 (cs) 2000-01-12
US6432400B1 (en) 2002-08-13
DE69825733D1 (de) 2004-09-23
AU5868698A (en) 1998-08-03
CN1248264A (zh) 2000-03-22
FR2758143A1 (fr) 1998-07-10

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