HUE066196T2 - 2,3,5-trimetil-6-nonilciklohexa-2,5-dién-1,4-dion alfa-szinukleinopátiák, tauopátiák és egyéb rendellenességek szuppresszálására és kezelésére - Google Patents
2,3,5-trimetil-6-nonilciklohexa-2,5-dién-1,4-dion alfa-szinukleinopátiák, tauopátiák és egyéb rendellenességek szuppresszálására és kezeléséreInfo
- Publication number
- HUE066196T2 HUE066196T2 HUE19801443A HUE19801443A HUE066196T2 HU E066196 T2 HUE066196 T2 HU E066196T2 HU E19801443 A HUE19801443 A HU E19801443A HU E19801443 A HUE19801443 A HU E19801443A HU E066196 T2 HUE066196 T2 HU E066196T2
- Authority
- HU
- Hungary
- Prior art keywords
- nonylcyclohexa
- synucleinopathies
- tauopathies
- dione
- diene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/02—Quinones with monocyclic quinoid structure
- C07C50/04—Benzoquinones, i.e. C6H4O2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
- C07C39/08—Dihydroxy benzenes; Alkylated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/02—Quinones with monocyclic quinoid structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862747080P | 2018-10-17 | 2018-10-17 | |
| US201862771570P | 2018-11-26 | 2018-11-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE066196T2 true HUE066196T2 (hu) | 2024-07-28 |
Family
ID=68503208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE19801443A HUE066196T2 (hu) | 2018-10-17 | 2019-10-17 | 2,3,5-trimetil-6-nonilciklohexa-2,5-dién-1,4-dion alfa-szinukleinopátiák, tauopátiák és egyéb rendellenességek szuppresszálására és kezelésére |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US11174212B2 (https=) |
| EP (2) | EP4257190A3 (https=) |
| JP (2) | JP7586815B2 (https=) |
| KR (1) | KR20210076956A (https=) |
| CN (2) | CN113365616A (https=) |
| AU (1) | AU2019362010A1 (https=) |
| BR (1) | BR112021007153A2 (https=) |
| CA (2) | CA3116866A1 (https=) |
| CL (1) | CL2021000948A1 (https=) |
| CO (1) | CO2021006356A2 (https=) |
| DK (1) | DK3866772T3 (https=) |
| EC (1) | ECSP21034596A (https=) |
| ES (1) | ES2968957T3 (https=) |
| FI (1) | FI3866772T3 (https=) |
| HU (1) | HUE066196T2 (https=) |
| IL (1) | IL282375A (https=) |
| MX (2) | MX2021004329A (https=) |
| MY (1) | MY210324A (https=) |
| PE (1) | PE20211600A1 (https=) |
| PH (1) | PH12021550859A1 (https=) |
| PL (1) | PL3866772T3 (https=) |
| SG (1) | SG11202103887VA (https=) |
| TN (1) | TN2021000075A1 (https=) |
| WO (1) | WO2020081879A2 (https=) |
| ZA (1) | ZA202102619B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EA038941B1 (ru) | 2007-11-06 | 2021-11-12 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | ПРОИЗВОДНЫЕ 4-(п-ХИНОНИЛ)-2-ГИДРОКСИБУТАНАМИДА ДЛЯ ЛЕЧЕНИЯ МИТОХОНДРИАЛЬНЫХ ЗАБОЛЕВАНИЙ |
| WO2017106786A1 (en) | 2015-12-16 | 2017-06-22 | Bioelectron Technology Corporation | Improved methods for enriching alpha-tocotrienol from mixed tocol compositions |
| US10703701B2 (en) | 2015-12-17 | 2020-07-07 | Ptc Therapeutics, Inc. | Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| TN2021000075A1 (en) | 2018-10-17 | 2023-01-05 | Ptc Therapeutics Inc | 2,3,5-TRIMETHYL-6-NONYLCYCLOHEXA-2,5-DIENE-1,4-DIONE FOR SUPPRESSING AND TREATING α-SYNUCLEINOPATHIES, TAUOPATHIES, AND OTHER DISORDERS |
| WO2021077034A1 (en) * | 2019-10-18 | 2021-04-22 | Ptc Therapeutics, Inc. | 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione for suppressing and treating hemoglobinopathy, thalassemia, sickle cell disease and other disorders |
| MX2024000445A (es) * | 2021-07-08 | 2024-04-05 | Ptc Therapeutics Inc | Composiciones farmaceuticas que comprenden 2,3,5-trimetil-6-nonilc iclohexa-2,5-dieno-1,4-diona. |
| WO2024050725A1 (en) | 2022-09-07 | 2024-03-14 | Ptc Therapeutics, Inc. | Methods of producing 2, 3, 5, 6-alkyl-1, 4-benzoquinones |
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2019
- 2019-10-17 TN TNP/2021/000075A patent/TN2021000075A1/en unknown
- 2019-10-17 CA CA3116866A patent/CA3116866A1/en active Pending
- 2019-10-17 ES ES19801443T patent/ES2968957T3/es active Active
- 2019-10-17 MX MX2021004329A patent/MX2021004329A/es unknown
- 2019-10-17 EP EP23193936.4A patent/EP4257190A3/en not_active Withdrawn
- 2019-10-17 SG SG11202103887VA patent/SG11202103887VA/en unknown
- 2019-10-17 AU AU2019362010A patent/AU2019362010A1/en not_active Abandoned
- 2019-10-17 EP EP19801443.3A patent/EP3866772B1/en active Active
- 2019-10-17 BR BR112021007153-9A patent/BR112021007153A2/pt unknown
- 2019-10-17 WO PCT/US2019/056836 patent/WO2020081879A2/en not_active Ceased
- 2019-10-17 CA CA3255913A patent/CA3255913A1/en active Pending
- 2019-10-17 KR KR1020217014520A patent/KR20210076956A/ko active Pending
- 2019-10-17 PE PE2021000524A patent/PE20211600A1/es unknown
- 2019-10-17 CN CN201980083477.1A patent/CN113365616A/zh active Pending
- 2019-10-17 HU HUE19801443A patent/HUE066196T2/hu unknown
- 2019-10-17 CN CN202411357523.1A patent/CN119185268A/zh active Pending
- 2019-10-17 JP JP2021521219A patent/JP7586815B2/ja active Active
- 2019-10-17 DK DK19801443.3T patent/DK3866772T3/da active
- 2019-10-17 PL PL19801443.3T patent/PL3866772T3/pl unknown
- 2019-10-17 MY MYPI2021002086A patent/MY210324A/en unknown
- 2019-10-17 FI FIEP19801443.3T patent/FI3866772T3/fi active
-
2021
- 2021-03-30 US US17/218,042 patent/US11174212B2/en active Active
- 2021-04-15 MX MX2024005493A patent/MX2024005493A/es unknown
- 2021-04-16 CL CL2021000948A patent/CL2021000948A1/es unknown
- 2021-04-16 PH PH12021550859A patent/PH12021550859A1/en unknown
- 2021-04-18 IL IL282375A patent/IL282375A/en unknown
- 2021-04-20 ZA ZA2021/02619A patent/ZA202102619B/en unknown
- 2021-05-14 CO CONC2021/0006356A patent/CO2021006356A2/es unknown
- 2021-05-14 EC ECSENADI202134596A patent/ECSP21034596A/es unknown
- 2021-11-10 US US17/523,880 patent/US11667596B2/en active Active
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2022
- 2022-01-25 US US17/584,362 patent/US11746077B2/en active Active
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2023
- 2023-07-05 US US18/347,068 patent/US20230339835A1/en active Pending
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2024
- 2024-08-16 JP JP2024136955A patent/JP2024161510A/ja active Pending
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