HUE057218T2 - Plazmonikus chip, és fluoreszcens képet, illetve Raman spektroszkópiát alkalmazó rákbetegség-diagnosztikai eljárás - Google Patents
Plazmonikus chip, és fluoreszcens képet, illetve Raman spektroszkópiát alkalmazó rákbetegség-diagnosztikai eljárásInfo
- Publication number
- HUE057218T2 HUE057218T2 HUE15789355A HUE15789355A HUE057218T2 HU E057218 T2 HUE057218 T2 HU E057218T2 HU E15789355 A HUE15789355 A HU E15789355A HU E15789355 A HUE15789355 A HU E15789355A HU E057218 T2 HUE057218 T2 HU E057218T2
- Authority
- HU
- Hungary
- Prior art keywords
- raman spectroscopy
- fluorescent image
- disease diagnosis
- cancer disease
- methods respectively
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
- G01N21/553—Attenuated total reflection and using surface plasmons
- G01N21/554—Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57473—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen, i.e. CEA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Ecology (AREA)
- Biophysics (AREA)
- Nanotechnology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Microscoopes, Condenser (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2014/062318 WO2014181816A1 (ja) | 2013-05-08 | 2014-05-08 | 癌関連物質のラマン定量方法 |
| JP2015036645 | 2015-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE057218T2 true HUE057218T2 (hu) | 2022-04-28 |
Family
ID=54392561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE15789355A HUE057218T2 (hu) | 2014-05-08 | 2015-05-07 | Plazmonikus chip, és fluoreszcens képet, illetve Raman spektroszkópiát alkalmazó rákbetegség-diagnosztikai eljárás |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10215700B2 (hu) |
| EP (1) | EP3141888B1 (hu) |
| JP (2) | JP6492066B2 (hu) |
| KR (1) | KR102232197B1 (hu) |
| CN (1) | CN106461556B (hu) |
| AU (1) | AU2015256932B2 (hu) |
| CA (1) | CA2948353C (hu) |
| ES (1) | ES2905092T3 (hu) |
| HU (1) | HUE057218T2 (hu) |
| IL (1) | IL248760B (hu) |
| MY (1) | MY193573A (hu) |
| NZ (1) | NZ726748A (hu) |
| SG (1) | SG11201609331XA (hu) |
| WO (1) | WO2015170711A1 (hu) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017156104A (ja) * | 2016-02-29 | 2017-09-07 | 西松建設株式会社 | 光増強素子とその製造方法ならびに分光分析用キットおよび分光分析方法 |
| GB201704128D0 (en) * | 2017-03-15 | 2017-04-26 | Univ Swansea | Method and apparatus for use in diagnosis and monitoring of colorectal cancer |
| CN108169184B (zh) * | 2017-09-05 | 2021-01-05 | 哈尔滨工业大学 | 一种肿瘤分类鉴别模型的建立方法及其应用 |
| CN108469429B (zh) * | 2018-02-06 | 2020-11-24 | 西安电子科技大学 | 一种双模态拉曼-光学投影断层成像系统 |
| JP2021156576A (ja) * | 2018-06-21 | 2021-10-07 | 有限会社マイテック | 疾病関連タンパク結合体を標的とする自家蛍光によるリキッド・バイオプシィ法 |
| EP4083223A4 (en) * | 2019-12-25 | 2024-01-17 | MYTECH Co., Ltd. | AUTOFLUORESCENCE-BASED LIQUID BIOPSY METHOD TARGETING NUCLEOSOMES FRAGMENTED BY APOPTOSIS |
| US11609229B2 (en) * | 2020-04-30 | 2023-03-21 | Mytech Co. Ltd. | Fluorescence counting system for quantifying viruses or antibodies on an immobilized metal substrate by using an antigen-antibody reaction |
| CN111624186B (zh) * | 2020-06-24 | 2021-03-16 | 江南大学 | 一种基于荧光和拉曼双信号增强的肠毒素光谱分析方法 |
| TWI818278B (zh) * | 2020-11-20 | 2023-10-11 | 日商米特奇有限公司 | 透過自體螢光的液態生檢法 |
| KR20220091408A (ko) * | 2020-12-22 | 2022-06-30 | 두에이아이(주) | 인공지능 라만 분석 기법을 이용한 췌장암 조기진단 방법 |
| KR102530499B1 (ko) * | 2021-08-26 | 2023-05-10 | 한밭대학교 산학협력단 | 플라즈몬 금속 나노입자를 이용한 세포핵 내 단백질 검출방법 |
| CN114550816B (zh) * | 2022-03-01 | 2022-11-04 | 上海图灵智算量子科技有限公司 | 基于光子芯片病毒变异概率的预测方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5255067A (en) * | 1990-11-30 | 1993-10-19 | Eic Laboratories, Inc. | Substrate and apparatus for surface enhanced Raman spectroscopy |
| JP2010517582A (ja) | 2007-02-12 | 2010-05-27 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 結腸癌の早期検出および予後診断の方法 |
| EP2755031B1 (en) * | 2007-03-20 | 2017-05-03 | Becton, Dickinson and Company | Assay using surface-enhanced raman spectroscopy (sers)-active particles |
| US8243271B2 (en) * | 2009-02-26 | 2012-08-14 | Pchem Associates, Inc. | Methods for fabricating analytical substrates using metallic nanoparticles |
| JP5466226B2 (ja) | 2009-03-04 | 2014-04-09 | 有限会社マイテック | 表面増強ラマン散乱活性測定基板 |
| BR112012001333A2 (pt) | 2009-07-21 | 2015-09-01 | Hills Pet Nutrition Inc | Sistema de nutrição, sistema de perda de peso para um animal de companhia em necessidade de perder peso, e, método para administrar a absorção nutricional de um animal de companhia. |
| CN102072891B (zh) * | 2009-11-20 | 2012-04-25 | 中国科学院化学研究所 | 金属修饰的光子晶体生物检测薄膜及其制备方法和用途 |
| JP5544653B2 (ja) | 2010-02-02 | 2014-07-09 | 独立行政法人産業技術総合研究所 | 抗原抗体反応の検出方法 |
| EP2615059B1 (en) * | 2010-09-06 | 2017-11-08 | Mytech Co., Ltd. | Method for producing metal complex quantum crystals |
| JP6091417B2 (ja) | 2011-09-13 | 2017-03-08 | 国立大学法人九州大学 | 金属ナノ粒子を用いた呈色膜および呈色方法 |
| WO2013065747A1 (ja) * | 2011-10-31 | 2013-05-10 | 有限会社マイテック | 金属錯体量子結晶及びそれを用いる生化学物質の表面増強ラマン散乱（ｓｅｒｓ）分析法 |
| US8810789B2 (en) * | 2011-11-07 | 2014-08-19 | University Of Georgia Research Foundation, Inc. | Thin layer chromatography-surfaced enhanced Raman spectroscopy chips and methods of use |
| US9134248B2 (en) * | 2011-11-29 | 2015-09-15 | Ondavia, Inc. | Systems for analyte detection |
| JP6054030B2 (ja) * | 2011-12-23 | 2016-12-27 | 有限会社マイテック | 金属錯体量子結晶の作成方法 |
| JP5975480B2 (ja) | 2012-01-31 | 2016-08-23 | 国立研究開発法人産業技術総合研究所 | バイオチップ、バイオアッセイ用キット、及びバイオアッセイ方法 |
| JP6294614B2 (ja) * | 2013-05-08 | 2018-03-14 | 有限会社マイテック | 癌関連物質の定量方法 |
| JP2014219623A (ja) | 2013-05-10 | 2014-11-20 | ソニー株式会社 | 観測システム、観測プログラム及び観測方法 |
-
2015
- 2015-05-07 JP JP2016517920A patent/JP6492066B2/ja active Active
- 2015-05-07 EP EP15789355.3A patent/EP3141888B1/en active Active
- 2015-05-07 SG SG11201609331XA patent/SG11201609331XA/en unknown
- 2015-05-07 KR KR1020167034270A patent/KR102232197B1/ko active IP Right Grant
- 2015-05-07 AU AU2015256932A patent/AU2015256932B2/en active Active
- 2015-05-07 ES ES15789355T patent/ES2905092T3/es active Active
- 2015-05-07 NZ NZ726748A patent/NZ726748A/en unknown
- 2015-05-07 MY MYPI2016704066A patent/MY193573A/en unknown
- 2015-05-07 WO PCT/JP2015/063219 patent/WO2015170711A1/ja active Application Filing
- 2015-05-07 CN CN201580023965.5A patent/CN106461556B/zh active Active
- 2015-05-07 CA CA2948353A patent/CA2948353C/en active Active
- 2015-05-07 HU HUE15789355A patent/HUE057218T2/hu unknown
- 2015-07-09 JP JP2015137686A patent/JP2016208959A/ja active Pending
-
2016
- 2016-11-06 IL IL248760A patent/IL248760B/en active IP Right Grant
- 2016-11-08 US US15/346,078 patent/US10215700B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2948353C (en) | 2021-12-14 |
| JPWO2015170711A1 (ja) | 2017-04-20 |
| EP3141888A4 (en) | 2018-03-14 |
| CA2948353A1 (en) | 2015-11-12 |
| US20170115216A1 (en) | 2017-04-27 |
| EP3141888B1 (en) | 2021-11-03 |
| KR102232197B1 (ko) | 2021-03-25 |
| NZ726748A (en) | 2020-05-29 |
| IL248760A0 (en) | 2017-01-31 |
| KR20170007774A (ko) | 2017-01-20 |
| SG11201609331XA (en) | 2016-12-29 |
| AU2015256932B2 (en) | 2019-11-07 |
| ES2905092T3 (es) | 2022-04-07 |
| JP6492066B2 (ja) | 2019-03-27 |
| AU2015256932A1 (en) | 2016-12-08 |
| US10215700B2 (en) | 2019-02-26 |
| CN106461556A (zh) | 2017-02-22 |
| JP2016208959A (ja) | 2016-12-15 |
| EP3141888A1 (en) | 2017-03-15 |
| MY193573A (en) | 2022-10-19 |
| CN106461556B (zh) | 2019-12-27 |
| IL248760B (en) | 2021-01-31 |
| WO2015170711A1 (ja) | 2015-11-12 |
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